Cell Surface Grp78 A New Paradigm In Signal Transduction Biology PDF Download
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| Author | : Salvatore V. Pizzo |
| Publisher | : Academic Press |
| Total Pages | : 146 |
| Release | : 2018-03-20 |
| Genre | : Science |
| ISBN | : 0128123524 |
Download Cell Surface GRP78, a New Paradigm in Signal Transduction Biology Book in PDF, ePub and Kindle
Cell Surface GRP78, a New Paradigm in Signal Transduction Biology presents a new paradigm that has emerged in the past decade with the discovery that various intracellular proteins may acquire new functions as cell surface receptors. Two very prominent examples are ATP synthase and GRP78. While the role of cell surface ATP synthase has been reviewed in various books, this book directs its attention to the story of cell surface GRP78. Edited by the researcher who identified cell surface expression of the molecular chaperone GRP78 as a major factor in prostate cancer and other malignancies Presents an in-depth treatment of the biological underpinnings of GRP78 and its connection to disease Provides four-color illustrations that facilitate the narrative
| Author | : Michel Goldberg |
| Publisher | : Springer Nature |
| Total Pages | : 305 |
| Release | : 2021-09-30 |
| Genre | : Medical |
| ISBN | : 3030762831 |
Download Extracellular Matrix Biomineralization of Dental Tissue Structures Book in PDF, ePub and Kindle
This book addresses the structural and biological properties of dental and peridental tissue structures and covers their mineralization process. The book contains a description of dentines, cementum, enamel and bone, including collagens, as well as non-collagenous proteins (SIBLINGs, SLRPs, GAGs, PGs, lipids, and MMPs). The mechanisms of mineralization are described in detail and the book is focused on matrix vesicles, collagen mineralization and the role of non-collagenous extracellular matrix components either as promoters or inhibitors of mineralization. In addition, the matrix components (non-collagenous) of enamel (amelogenin, ameloblastin, enamelin, MMP4, MMP20 and other proteases) are reviewed and their respective roles in dental tissues biomineralizations and tissue turnover are discussed. Additionally, environmental factors involved in enamel / dentin defects are adressed. With state-of-the-art contributions from experts in the respective domains, the book is a useful introduction to the field for junior scientists, interested in dental and peridental tissue biomineralization. It is also an interesting read for advanced scientists and clinicians working in dental research, giving them a broader view of the topic beyond their area of specialization. The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology.
| Author | : Ramasamy Paulmurugan |
| Publisher | : Academic Press |
| Total Pages | : 832 |
| Release | : 2021-06-25 |
| Genre | : Science |
| ISBN | : 0128215682 |
Download Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies Book in PDF, ePub and Kindle
Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies brings current knowledge from an international team of experts on the science and clinical management of glioblastoma chemoresistance. The book discusses topics such as molecular mechanisms of chemoresistance, experimental models to study chemoresistance, chemoresistance to drugs other than Temozolomide, and specific strategies to reverse chemoresistance. Additionally, it encompasses information on how to mitigate chemoresistance by targeted enhancement of p53 function. This book is a valuable resource for cancer researchers, oncologists, neuro-oncologists and other members of the biomedical field. Glioblastoma (GBM) is the most invasive and malignant primary brain tumor in humans with poor survival after diagnosis, therefore it is imperative that molecular and cellular mechanisms behind therapy resistant GBM cells, as well as the therapeutic strategies available to counter the resistance are comprehensively understood. Provides comprehensive, core knowledge related to the entire discipline of glioblastoma chemoresistance, from its many etiological mechanisms, to specific strategies to reverse resistance Presents current information from an international team of experts on the basic science, pre-clinical research, and clinical management of glioblastoma chemoresistance Discusses molecular and cellular mechanisms behind therapy resistant glioblastoma cells, as well as the therapeutic strategies available to counter this resistance
| Author | : Alan R. Saltiel |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 223 |
| Release | : 2007-10-05 |
| Genre | : Medical |
| ISBN | : 0387722041 |
Download Mechanisms of Insulin Action Book in PDF, ePub and Kindle
More than 18 million people in the United States have diabetes mellitus, and about 90% of these have the type 2 form of the disease. This book attempts to dissect the complexity of the molecular mechanisms of insulin action with a special emphasis on those features of the system that are subject to alteration in type 2 diabetes and other insulin resistant states. It explores insulin action at the most basic levels, through complex systems.
| Author | : Sergio Cimerman |
| Publisher | : Frontiers Media SA |
| Total Pages | : 242 |
| Release | : 2023-09-28 |
| Genre | : Medical |
| ISBN | : 2832534430 |
Download New therapeutic approaches for SARS-CoV-2/COVID-19 Book in PDF, ePub and Kindle
| Author | : Kjell Fuxe |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 577 |
| Release | : 2013-03-13 |
| Genre | : Computers |
| ISBN | : 1468454153 |
Download Receptor-Receptor Interactions Book in PDF, ePub and Kindle
| Author | : Saman Warnakulasuriya |
| Publisher | : Springer Nature |
| Total Pages | : 449 |
| Release | : 2020-02-22 |
| Genre | : Medical |
| ISBN | : 3030323161 |
Download Textbook of Oral Cancer Book in PDF, ePub and Kindle
This comprehensive multidisciplinary book examines all aspects of cancers of the mouth and oropharynx with the aim of equipping advanced students and practitioners in the early stages of specialist training with an up-to-date guide and reference. A multinational team of authors – all experts in the field of oral oncology – provide illuminating contributions on the full range of relevant topics: epidemiology, risk factors, clinical features, staging and prognostic factors, pathology, diagnostic techniques, disease prevention, surgery, radiotherapy, and chemotherapy. Molecular biology, molecular targeted therapies for advanced cases, and future diagnostic and prognostic applications of new technologies also receive careful attention. In providing a wealth of essential information and guidance in a practical format, the book will be a superb asset for senior graduate students in dentistry and specialist trainees in head and neck oncology. It will also be of high value for the many physicians, surgeons, pathologists, dentists, and specialists involved in the prevention, diagnosis, and management of squamous cell carcinomas of the oral cavity and oropharynx.
| Author | : Nava Segev |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 459 |
| Release | : 2010-05-30 |
| Genre | : Science |
| ISBN | : 038793877X |
Download Trafficking Inside Cells Book in PDF, ePub and Kindle
This book covers the past, present and future of the intra-cellular trafficking field, which has made a quantum leap in the last few decades. It details how the field has developed and evolved as well as examines future directions.
| Author | : Dong-Hee Lee |
| Publisher | : Springer |
| Total Pages | : 1181 |
| Release | : 2017-08-28 |
| Genre | : Science |
| ISBN | : 9402410791 |
Download Taurine 10 Book in PDF, ePub and Kindle
Taurine 10 contains original articles and critical reviews based on the oral and poster presentations of XX International Taurine Meeting held in Seoul, Korea in May 2016. The purpose of the book is to present current ideas, new avenues and research regarding biological functions and clinical applications of taurine and taurine derivatives. It focuses on all aspects of taurine research including the cardiovascular system, the immune system, diabetes, the central nervous system, endocrine system and the role of taurine supplements in nutrition. It also includes presentations of novel animal experimental models using Cdo1 and CSAD knock-out mice.
| Author | : Seyed Ehtesham Hasnain |
| Publisher | : Springer |
| Total Pages | : 514 |
| Release | : 2019-12-11 |
| Genre | : Medical |
| ISBN | : 9789813294127 |
Download Mycobacterium Tuberculosis: Molecular Infection Biology, Pathogenesis, Diagnostics and New Interventions Book in PDF, ePub and Kindle
This book reviews recent advances in the molecular and infection biology, pathology, and molecular epidemiology of Mycobacterium tuberculosis, as well as the identification and validation of novel molecular drug targets for the treatment of this mycobacterial disease. Despite being completely curable, tuberculosis is still one of the leading global causes of death. M. tuberculosis, the causative organism – one of the smartest pathogens known – adopts highly intelligent strategies for survival and pathogenesis. Presenting a wealth of information on the molecular infection biology of M. tuberculosis, as well as nontuberculous mycobacteria (NTM), the book provides an overview of the functional role of the PE/PPE group of proteins, which is exclusive to the genus Mycobacteria, of host-pathogen interactions, and virulence. It also explores the pathogenesis of the infection, pathology, epidemiology, and diagnosis of NTM. Finally it discusses current and novel approaches in vaccine development against tuberculosis, including the role of nanotechnology. With state-of-the-art contributions from experts in the respective domains, this book is an informative resource for practitioners as well as medical postgraduate students and researchers.
