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Cell Movement in Health and Disease

Cell Movement in Health and Disease
Author: Michael Schnoor
Publisher: Academic Press
Total Pages: 386
Release: 2022-03-30
Genre: Science
ISBN: 0323901964

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Cell Movement in Health and Disease brings the several scientific domains related to the phenomena together, establishing a consistent foundation for researchers in this exciting field. The content is presented in four main section. The first explores the foundations of Cell Movement, including overviews of cellular structure, signaling, physiology, motion-related proteins, and the interface with the cellular membrane. The second part covers the biological aspects of cellular movement, starting with chemical and mechanical sensing, describing the types of cell movement, mechanics at cell level, cell physiology, collective behavior, and the connections with the extracellular matrix. The following chapters provide an overview of the molecular machinery involved and cell-type specific movement. The third part of the book is dedicated to the translational aspects of cell movement, highlighting the key conditions associated with cell movement dysfunction, like cell invasion in cancer, wound healing, developmental issues, neurological dysfunctions, and immune response. The final part of the book covers key methods and modeling tools for cell movement research, including predictive mathematical models, in vitro and in vivo methods, biophysical and bioinformatics tools. Cell Movement in Health and Disease is the ideal reference for scientists from different backgrounds converging to expand the understanding of this key cellular process. Cellular and molecular biologists will gain a better understanding of the physical principals operating at cellular level while biophysicist and biomedical engineers will benefit from the solid biology foundation provided by the book. Combines Biology, Physics and Modeling of cellular movement in one single source Updated with the current understanding of the field Includes key research methods for cell movement investigation Cover translational aspects of cellular movement


The Cytoskeleton in Health and Disease

The Cytoskeleton in Health and Disease
Author: Heide Schatten
Publisher: Springer
Total Pages: 395
Release: 2015-08-21
Genre: Science
ISBN: 1493929046

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This volume addresses the structural and functional roles of the cytoskeleton and its dysfunctions which often lead to disease. It provides thorough discussion of microtubules, microfilaments, intermediate filaments, and cytoskeletal functions and dysfunctions in different organ systems. Comprehensive yet concise. The Cytoskeleton In Health And Disease presents cutting-edge discoveries balanced with background information and highlights the new aspects of the research and its impact on the design of new strategies or the identification of new targets for therapeutic intervention. There is a significant need for a book on this topic, as interest in the cytoskeleton continues to grow as causes and cures for cytoskeletal diseases are further explored in biomedical research. This book is essential reading for scientists, students, and teachers interested in expanding their knowledge related to the cytoskeleton. New researchers entering the field will find classic and well as contemporary information not easily found in the current literature or internet resources.


Mechanobiology in Health and Disease

Mechanobiology in Health and Disease
Author: Stefaan Verbruggen
Publisher: Academic Press
Total Pages: 527
Release: 2018-08-09
Genre: Technology & Engineering
ISBN: 0128129530

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Mechanobiology in Health and Disease brings together contributions from leading biologists, clinicians, physicists and engineers in one convenient volume, providing a unified source of information for researchers in this highly multidisciplinary area. Opening chapters provide essential background information on cell mechanotransduction and essential mechanobiology methods and techniques. Other sections focus on the study of mechanobiology in healthy systems, including bone, tendons, muscles, blood vessels, the heart and the skin, as well as mechanobiology studies of pregnancy. Final chapters address the nascent area of mechanobiology in disease, from the study of bone conditions, skin diseases and heart diseases to cancer. A discussion of future perspectives for research completes each chapter in the volume. This is a timely resource for both early-career and established researchers working on mechanobiology. Provides an essential digest of primary research from many fields and disciplines in one convenient volume Covers both experimental approaches and descriptions of mechanobiology problems from mathematical and numerical perspectives Addresses the hot topic of mechanobiology in disease, a particularly dynamic field of frontier science


Cell Migration

Cell Migration
Author: Frank Entschladen
Publisher: Karger Medical and Scientific Publishers
Total Pages: 185
Release: 2010
Genre: Science
ISBN: 380559321X

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Cell migration is a highly complex process which involves several compartments of the cell, including surface receptors, signalling elements and the cytoskeleton. It plays an essential role in embryogenesis, wound healing and inflammatory responses, and a dysregulation of cell movement can cause pathological states such as developmental defects, chronic inflammation, cancer invasion and metastasis. Covering extracellular regulatory signals and intracellular signal transduction pathways as well as the molecular mechanisms of migration in stem cells, leukocytes and tumor cells in the adult human organism, this book summarizes the current state of knowledge about cell migration. In the first part, the major aspects of different migratory cells in health and disease are covered, with special emphasis on T lymphocytes. The second part provides a comprehensive overview of the principal molecular mechanisms of migration such as adhesion receptors, cytoskeletal rearrangements and locomotor force generation, which, together, can be referred to as a cell's 'migrosome'.With contributions by eminent international scientists from different disciplines this book will serve as a valuable resource not only for researchers in cell biology, immunology and oncology, but also for clinicians who wish to learn more about the role of migratory processes in health and disease.


Immune Cell Migration in Health and Disease

Immune Cell Migration in Health and Disease
Author: Hélène D. Moreau
Publisher: Frontiers Media SA
Total Pages: 178
Release: 2022-05-04
Genre: Medical
ISBN: 288976088X

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Exercise Physiology

Exercise Physiology
Author: Stanley P. Brown
Publisher: Lippincott Williams & Wilkins
Total Pages: 695
Release: 2006
Genre: Medical
ISBN: 0781777305

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Bridging the gap between exercise physiology principles and clinical practice, this text provides comprehensive coverage of both traditional basic science and clinical exercise physiology principles. The book presents clinical applications and examples that connect theory to practice. More than 500 full-color illustrations and numerous graphs and tables complement the text. Reader-friendly features including Perspective Boxes, Research Highlights, Biography Boxes, and Case Studies engage readers and reinforce key concepts. A bonus three-dimensional interactive anatomy CD-ROM from Primal Pictures and a Student Resource CD-ROM accompany the book. LiveAdvise online faculty support and student tutoring services are available free with the text.


Cellular Trafficking of Cell Stress Proteins in Health and Disease

Cellular Trafficking of Cell Stress Proteins in Health and Disease
Author: Brian Henderson
Publisher: Springer
Total Pages: 298
Release: 2012-11-20
Genre: Medical
ISBN: 9789400747418

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Since the beginning of the 21st Century there has been a rapid increase in our understanding of the cellular trafficking mechanisms of molecular chaperones in eukaryotes and in prokaryotes. In the former, molecular chaperone trafficking can occur between the various cellular compartments, with concomitant movement of other proteins. Such events can also result in the release of molecular chaperones from cells. In bacteria, molecular chaperones are involved in the trafficking of other proteins and are themselves released into the external milieu. The increasing appreciation of the role of molecular chaperones and Protein-Folding Catalysts in the interplay between bacteria and the cells of their hosts is now an important area of research for understanding the mechanisms of infectious diseases. This volume brings together experts in the biochemistry, cellular biology, immunology and molecular biology of molecular chaperones and Protein-Folding Catalysts with a focus on the mechanisms of cellular trafficking of these proteins and the role of these variegated trafficking mechanisms in both human and animal health and disease.


Molecular Biology of The Cell

Molecular Biology of The Cell
Author: Bruce Alberts
Publisher:
Total Pages: 0
Release: 2002
Genre: Cytology
ISBN: 9780815332183

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The Lives of a Cell

The Lives of a Cell
Author: Lewis Thomas
Publisher: Penguin
Total Pages: 160
Release: 1978-02-23
Genre: Science
ISBN: 1101667052

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Elegant, suggestive, and clarifying, Lewis Thomas's profoundly humane vision explores the world around us and examines the complex interdependence of all things. Extending beyond the usual limitations of biological science and into a vast and wondrous world of hidden relationships, this provocative book explores in personal, poetic essays to topics such as computers, germs, language, music, death, insects, and medicine. Lewis Thomas writes, "Once you have become permanently startled, as I am, by the realization that we are a social species, you tend to keep an eye out for the pieces of evidence that this is, by and large, good for us."


Tooth Movement

Tooth Movement
Author: Alpdogan Kantarci
Publisher: Karger Medical Scientific
Total Pages: 0
Release: 2016
Genre: Orthodontics
ISBN: 9783318054798

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With the intention of improving the rate, quality, and stability of orthodontic tooth movement, those in the field are now moving toward accomplishing this 'acceleration' with minimally or non-invasive methods. New procedures have been widely tested in humans, animal models, and in vitro. While interest is growing both in the industry and at the clinical level, the understanding of the biology is limited. Considering that a simple increase in force will result in tooth morbidity and arrest of the tooth migration, a multi-disciplinary approach is critical for success. This publication brings together multi-disciplinary expertise on a wide variety of processes related to and involved in orthodontic tooth movement. The premise is that, by better understanding the biological structures and the mechanism through which they respond to biomechanical forces, one can get a better assessment of the 'acceleration'. This work presents research aimed at an improved understanding of conventional and accelerated orthodontic tooth movement from a biological perspective and will be of great value to clinicians, researchers, academics, and students.