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| Author | : José Luis Sardina |
| Publisher | : Frontiers Media SA |
| Total Pages | : 171 |
| Release | : 2021-10-20 |
| Genre | : Science |
| ISBN | : 2889715108 |
| Author | : Chin-Hsing Annie Lin |
| Publisher | : Frontiers Media SA |
| Total Pages | : 104 |
| Release | : 2016-06-24 |
| Genre | : Genetics |
| ISBN | : 2889198529 |
The fundamental question of how an undifferentiated progenitor cell adopts a more specialized cell fate that then contributes to the development of specialized tissues, organs, organ systems and ultimately a unique individual of a given species has intrigued cell and developmental biologists for many years. Advances in molecular and cell biology have enabled investigators to identify genetic and epigenetic factors that contribute to these processes with increasing detail and also to define the various molecular characteristics of each cell fate with greater precision. Understanding these processes have also provided greater insights into disorders in which the normal mechanisms of cell fate determination are altered, such as in cancer and inherited malformations. With these advances have come techniques that facilitate the manipulation of cell fate, which have the potential to revolutionize the field of medicine by facilitating the repair and/or regeneration of diseased organs. Given the rapid advances that are occurring in the field, the articles in this eBook are both relevant and timely. These articles originally appeared online as part of the Research Topic “Cell Fate” overseen by my colleagues Dr. Lin, Dr. Buttitta, Dr. Maves, Dr. Dilworth, Dr. Paladini and myself and have been viewed extensively. Because of their popularity, they are now made available as an eBook, in a more easily downloadable form. Michael T. Chin
| Author | : Simon M. Cool |
| Publisher | : |
| Total Pages | : 129 |
| Release | : 2007 |
| Genre | : |
| ISBN | : |
| Author | : Junren Sia |
| Publisher | : |
| Total Pages | : 77 |
| Release | : 2016 |
| Genre | : |
| ISBN | : |
| Author | : Cheryl Chang |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2015-01-19 |
| Genre | : |
| ISBN | : 9781632422866 |
This book presents an insight into the understanding of neural stem cell fate decisions. Over the past few decades, several studies on regenerative medicine and stem cells have emphasized on novel therapeutic techniques for treatment of many neurological disorders. It has been observed that the present optimism over potential stem cell therapies has propagated from novel comprehensions of stem cell biology leading to particular cell fate decision. This book aims at providing a basic understanding of signaling pathways underlying the ability of differentiation of various types of stem cells into neurons at the time of development; elucidating progress in cellular therapy that could be employed to recover central nervous system dysfunction in pathological conditions; and helping readers to comprehend the changes in signaling pathways under pathological conditions.
| Author | : Chunhe Li |
| Publisher | : Frontiers Media SA |
| Total Pages | : 253 |
| Release | : 2022-11-21 |
| Genre | : Science |
| ISBN | : 2832506550 |
| Author | : Patrick Cahan |
| Publisher | : Humana |
| Total Pages | : 0 |
| Release | : 2019-05-07 |
| Genre | : Science |
| ISBN | : 9781493992232 |
This volume details methods and protocols to further the study of stem cells within the computational stem cell biology (CSCB) field. Chapters are divided into four sections covering the theory and practice of modeling of stem cell behavior, analyzing single cell genome-scale measurements, reconstructing gene regulatory networks, and metabolomics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Computational Stem Cell Biology: Methods and Protocols will be an invaluable guide to researchers as they explore stem cells from the perspective of computational biology.
| Author | : C.H. Waddington |
| Publisher | : Routledge |
| Total Pages | : 231 |
| Release | : 2014-04-29 |
| Genre | : History |
| ISBN | : 1317657543 |
First published in 1957, this essential classic work bridged the gap between analytical and theoretical biology, thus setting the insights of the former in a context which more sensitively reflects the ambiguities surrounding many of its core concepts and objectives. Specifically, these five essays are concerned with some of the major problems of classical biology: the precise character of biological organisation, the processes which generate it, and the specifics of evolution. With regard to these issues, some thinkers suggest that biological organisms are not merely distinguishable from inanimate ‘things’ in terms of complexity, but are in fact radically different qualitatively: they exemplify some constitutive principle which is not elsewhere manifested. It is the desire to bring such ideas into conformity with our understanding of analytical biology which unifies these essays. They explore the contours of a conceptual framework sufficiently wide to embrace all aspects of living systems.
| Author | : Michal K. Stachowiak |
| Publisher | : World Scientific |
| Total Pages | : 394 |
| Release | : 2012 |
| Genre | : Medical |
| ISBN | : 9814317934 |
Fast-moving and ever-changing, stem cell science and research presents ongoing ethical and legal challenges in many countries. Each development and innovation throws up new challenges. This is the case even where new developments initially seem to solve old dilemmas. Sometimes it becomes evident that new science does not in fact solve old problems and, for that reason, the ethical issues remain. In recognition of this, this book presents innovative and creative analyses of a range of ethical and legal challenges raised by stem cell research and its potential and actual application. The editors.
| Author | : Michael Floßdorf |
| Publisher | : |
| Total Pages | : 103 |
| Release | : 2013 |
| Genre | : |
| ISBN | : |
