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Cell Biology of Herpes Viruses

Cell Biology of Herpes Viruses
Author: Klaus Osterrieder
Publisher: Springer
Total Pages: 226
Release: 2017-05-20
Genre: Medical
ISBN: 3319531689

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Herpes viruses are widely distributed in nature, causing disease in organisms as diverse as bivalves and primates, including humans. Each virus appears to have established a long-standing relationship with its host, and the viruses have the ability to manipulate and control the metabolism of host cells, as well as innate and adaptive antiviral immune responses. Herpes viruses maintain themselves within hosts in a latent state resulting in virus persistence for years – usually for the life span of the hosts. Herpes viruses comprise a large number of pathogens with diverse cellular targets and biological consequences of infection. What they have in common is their structure and the fact that they establish a dormant (latent) infection in their hosts that usually persists for life. The reviews here will highlight the general principles of herpes virus infection, with equal attention to overall principle and important difference. Also, the cell type- and life-style dependent differences in the establishment and maintenance of virus persistence will be covered.


Human Herpesviruses

Human Herpesviruses
Author: Ann Arvin
Publisher: Cambridge University Press
Total Pages: 1325
Release: 2007-08-16
Genre: Medical
ISBN: 1139461648

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This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.


Molecular Biology of The Cell

Molecular Biology of The Cell
Author: Bruce Alberts
Publisher:
Total Pages: 0
Release: 2002
Genre: Cytology
ISBN: 9780815332183

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Alpha Herpesviruses

Alpha Herpesviruses
Author: Rozanne M. Sandri-Goldin
Publisher: Caister Academic Press Limited
Total Pages: 0
Release: 2006
Genre: Science
ISBN: 9781904455097

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The alpha herpesviruses are an important group of viruses characterized by a short reproductive cycle, rapid destruction of the host cell, and the ability to replicate in a wide variety of host tissues. A key attribute of these viruses is the ability to establish lifelong latent infection in the peripheral nervous system of the natural host. Research into the molecular and cellular biology of the alpha herpesviruses has advanced greatly in recent years. Written by internationally recognized experts, this book highlights the more provocative and exciting findings in herpesvirus research. Each chapter is a review of a specific area with an emphasis on recent advances and the latest developments. The book examines multifunctional proteins, advances in DNA replication, new information on the regulation of gene expression, the emergence of new technologies, recent technological advances in fluorescent probes, the induction of apoptosis, the disruption of interferon, vaccine development, and drug design. With a specific focus on new and topical herpesvirus research, Alpha Herpesviruses is essential reading for everyone with an interest in herpesviruses and it is recommended reading for other scientists working in viral pathogenesis, viral genomics, and antiviral research.


Scanning Electron Microscopy for the Life Sciences

Scanning Electron Microscopy for the Life Sciences
Author: Heide Schatten
Publisher: Cambridge University Press
Total Pages: 275
Release: 2013
Genre: Science
ISBN: 0521195993

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A guide to modern scanning electron microscopy instrumentation, methodology and techniques, highlighting novel applications to cell and molecular biology.


The Human Herpesviruses

The Human Herpesviruses
Author: Bernard Roizman
Publisher: Raven Press (ID)
Total Pages: 458
Release: 1993
Genre: Medical
ISBN:

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Human Herpesviruses

Human Herpesviruses
Author: Yasushi Kawaguchi
Publisher: Springer
Total Pages: 501
Release: 2018-06-12
Genre: Medical
ISBN: 9811072302

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This book introduces and reviews several topics for each human herpesvirus. One of the most important features of the book is that it covers aspects of both basic research and clinical medicine. Herpesviridae, a family of double-strand DNA viruses, has unique biological features by which these viruses establish latency after primary infection and reactivate in later life. Nine human herpesviruses are known so far, and each of them causes a variety of diseases in both primary infection and reactivation. Since the discovery of each human herpesvirus, an abundance of findings related to them has accumulated in basic research and clinical medicine. However, the vast majority of biological features is still masked in mystery. Furthermore, a strategy of treatment and prevention has not yet been established for most human herpesviruses. A wide range of readers will be interested in this volume with its treatment of problematic points and latest findings in the field.


Pathogenicity of Human Herpesviruses due to Specific Pathogenicity Genes

Pathogenicity of Human Herpesviruses due to Specific Pathogenicity Genes
Author: Yechiel Becker
Publisher: Springer Science & Business Media
Total Pages: 391
Release: 2012-12-06
Genre: Medical
ISBN: 3642850049

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Six members of the Herpesviridae family are human pathogens, including herpes and 2 (HSV-I and 2), Epstein-Barr virus (EBV), varicella zoster simplex virus I virus (VZV), human cytomegalovirus (HCMV), and human herpesvirus 6 (HHV 6). Each of these viruses is capable of causing distinct diseases of varying severity in children, young adults, and the aged. The diseases range from infection of epithelial tissue to the infection of internal organs and white blood cells. A common feature of the six pathogenic human herpesviruses is their ability to latently infect different cell types in which the viral DNA is not integrated and is unable to express its pathogenicity. Reactivation of the herpesviruses is a result of cellular processes which reactivate viral genes, leading to virus progeny and to signs of infection. Due to their ability to become latent after initial infection, once the pathogenic herpesviruses infect children they are maintained throughout life, having the potential of cause various diseases upon reactivation.


Innate Immunity in Health and Disease

Innate Immunity in Health and Disease
Author: Shailendra K. Saxena
Publisher: BoD – Books on Demand
Total Pages: 416
Release: 2021-08-25
Genre: Medical
ISBN: 1838807659

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The book focuses on various aspects and properties of innate immunity, whose deep understanding is integral for safeguarding the human race from further loss of resources and economies due to innate immune response-mediated diseases. Throughout this book, we examine the individual mechanisms by which the innate immune response acts to protect the host from pathogenic infectious agents and other non-communicable diseases. Written by experts in the field, the volume discusses the significance of macrophages in infectious disease, tumor metabolism, and muscular disorders. Chapters cover such topics as the fate of differentiated macrophages and the molecular pathways that are important for the pathologic role of macrophages.


Herpes Simplex Virus

Herpes Simplex Virus
Author: Adrian Mindel
Publisher: Springer Science & Business Media
Total Pages: 166
Release: 2012-12-06
Genre: Medical
ISBN: 1447116836

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Herpes Simplex Virus is the fifth monograph to be published in the Bloomsbury Series of Clinical Science. It provides an authoritative review of the key issues related to this common clinical problem. The characteristics of the virus, its epidemiology and the diag nosis and management of the various forms of infection are all considered. Adrian Mindel is an international authority on this subject; he joined the Academic Department of Genito-urinary Medicine at the Middlesex Hospital in 1980 and has been actively involved in HSV research since that time. His major research interests include the epidemiology and treatment of genital herpes, the epidemi ology of neo-natal herpes and the many and varied features of HSV infections in immuno-compromised patients. The continuing aim of the Bloomsbury Series is to identify the growing areas of clinical research and relate these to current and future medical practice. In Herpes Simplex Virus such aspirations have been successfully achieved. London, May 1989 Jack Tinker Preface There has been considerable interest in herpes simplex viruses (HSV) over recent years. Amongst the many reasons for this are the introduction of safe and efficacious therapy, the recognition that HSV may cause life-threatening infections in neonates and immunocompromised patients, the observation that genital herpes is one of the commonest viral sexually transmitted diseases and the possible association of HSV with cervical cancer.