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Case Studies in Cancer

Case Studies in Cancer
Author: Lee, Richard J.
Publisher: W.W. Norton & Company
Total Pages: 10
Release: 2018-11-15
Genre: Science
ISBN: 0393679519

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Cancer is the focus of intense clinical and scientific interest. This research increasingly leverages our understanding of molecular biology for the development of targeted therapeutics. Well-selected case studies provide an opportunity to explain specific examples of cancers and their management in the context of engaging, patient-centered cases. This text is a clinical companion for WeinbergÕs The Biology of Cancer. However, it includes sufficient background and explanatory detail to be used on its own.


Case Studies in Cancer

Case Studies in Cancer
Author: Richard J. Lee
Publisher: Garland Science
Total Pages: 300
Release: 2018-04
Genre:
ISBN: 9780815345183

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The modern diagnosis and treatment of cancer is intricately tied to the molecular underpinnings of disease. Case Studies in Cancerhighlights the broad range of malignancies in which known molecular pathways contribute to tumorigenesis, as well as susceptibility or resistance to therapy. Carefully selected case studies taken from the literature and practice of oncology explain specific examples of cancers and their management in the context of patient-centered case, which expose readers to the broad biological and clinical spectrum of cancer. Examined against the background of historical observations and concepts emerging from research in the molecular biology of cancer, these case studies provide a set of lessons showing how findings at the bench and bedside inform, direct, and inspire each other. Each case is accompanied by take-home points and review questions. Chapter summaries are followed by thought questions and primary and review literature for further reference on the history, biology, and clinical management of oncological disease. This text is appropriate for students starting medical school and those taking advanced courses in cancer biology with a clinical component, as well as practitioners in the field.


Evaluation of Biomarkers and Surrogate Endpoints in Chronic Disease

Evaluation of Biomarkers and Surrogate Endpoints in Chronic Disease
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 335
Release: 2010-06-25
Genre: Medical
ISBN: 0309157277

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Many people naturally assume that the claims made for foods and nutritional supplements have the same degree of scientific grounding as those for medication, but that is not always the case. The IOM recommends that the FDA adopt a consistent scientific framework for biomarker evaluation in order to achieve a rigorous and transparent process.


Oxford Case Histories in Oncology

Oxford Case Histories in Oncology
Author: Thankamma Ajithkumar
Publisher:
Total Pages: 328
Release: 2014-03
Genre: Medical
ISBN: 0199664536

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Oxford Case Histories in Oncology contains 30 well-structured cases from clinical practice, giving a comprehensive coverage of the diagnostic and management dilemmas in oncology. The cases cover a wide spectrum of oncology including rare presentations and clinical problems of common cancers. Each case comprises a brief clinical history with relevant clinical examination findings. Questions are based on clinical investigations and aspects of management. Detailed answers are based on the best available evidence from the latest research, systematic reviews, meta-analysis and guidelines from national and international academic bodies. The text is complimented by over 50 illustrations, including radiographic images and radiotherapy treatment plans. The format of this book is thought provoking, and it helps to improve critical thinking and interpretative skills. It is a perfect self-assessment tool for oncology and palliative medicine trainees and consultants, and will be useful for those preparing for exit examinations in oncology. It will also be of interest to non-specialist readers who wish to improve their skills in the diagnosis and management of a broad range of cancers.


Cancer Screening in the Developing World

Cancer Screening in the Developing World
Author: Madelon L. Finkel, PhD
Publisher: Dartmouth College Press
Total Pages: 208
Release: 2018-05-01
Genre: Medical
ISBN: 1512602523

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Worldwide, cancer is responsible for one in eight deaths--more than AIDS, tuberculosis, and malaria combined. This global burden starkly illustrates the inequality between the developed and the developing world. While the majority of people living in developed countries receive timely treatment, those living in developing countries are not as fortunate and their survival rates are much lower--not only due to delays in diagnosis, but also to a lack of personnel, a paucity of treatment facilities, and the unavailability of many medications. Routine screening--a mainstay in the developed world--could greatly increase the likelihood of identifying individuals with early stage cancers and thus reduce the number of people who present with advanced disease. This book represents a critical addition to the literature of global health studies. Focusing on cervical, breast, and oral cancers, these case studies highlight innovative strategies in cancer screening in a diverse array of developing countries. The authors discuss common issues and share how obstacles--medical, economic, legal, social, and psychological--were addressed or overcome in specific settings. Each chapter offers an empirical discussion of the nature and scope of a screening program, the methodology used, and its findings, along with a candid discussion of challenges and limitations and suggestions for future efforts.


Improving the Quality of Cancer Clinical Trials

Improving the Quality of Cancer Clinical Trials
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 136
Release: 2008-05-12
Genre: Medical
ISBN: 0309178258

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Scientists and clinicians seek a new paradigm that could improve the efficiency, cost-effectiveness, and overall success rate of cancer clinical trials, while maintaining the highest standards of quality. To explore innovative paradigms for cancer clinical trials and other ways to improve their quality, the National Cancer Policy Forum held a workshop, Improving the Quality of Cancer Clinical Trials, in Washington, DC. The main goals of the workshop were to examine new approaches to clinical trial design and execution that would: (1) better inform decisions and plans of those responsible for developing new cancer therapies (2) more rapidly move new diagnostic tests and treatments toward regulatory approval and use in the clinic (3) be less costly than current trials The resulting workshop summary will serve as input to the deliberations of an Institute of Medicine committee that will develop consensus-based recommendations for moving the field of cancer clinical trials forward.


Advancing the Science of Implementation Across the Cancer Continuum

Advancing the Science of Implementation Across the Cancer Continuum
Author: David A. Chambers
Publisher: Oxford University Press, USA
Total Pages: 441
Release: 2018
Genre: Medical
ISBN: 0190647426

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While many effective interventions have been developed with the potential to significantly reduce morbidity and mortality from cancer, they are of no benefit to the health of populations if they cannot be delivered. In response to this challenge, Advancing the Science of Implementation across the Cancer Continuum provides an overview of research that can improve the delivery of evidence-based interventions in cancer prevention, early detection, treatment, and survivorship. Chapters explore the field of implementation science and its application to practice, a broad synthesis of relevant research and case studies illustrating each cancer-focused topic area, and emerging issues at the intersection of research and practice in cancer. Both comprehensive and accessible, this book is an ideal resource for researchers, clinical and public health practitioners, medical and public health students, and health policymakers.