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Cardiovascular Pharmacotherapeutics

Cardiovascular Pharmacotherapeutics
Author: Edmund H. Sonnenblick
Publisher: McGraw-Hill Professional
Total Pages: 1112
Release: 2003
Genre: Medical
ISBN:

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EVERYTHING PRACTICING PHYSICIANS AND PHARMACISTS NEED TO KNOW ABOUT DRUG THERAPY FOR HEART CONDITIONS The updated Second Edition of this classic brings you fully up to speed on… All the cardiovascular agents now available Mechanisms of action of cardiovascular pharmacotherapeutics Specific drug treatments Drugs in development Molecular biological advances More A compendium of valuable, updated pharmacotherapeutic information for managing patients with cardiovascular disease Cardiovascular Pharmacotherapeutics has long been considered the primary reference for practicing physicians and pharmacists who need to know about drug therapy for heart conditions. This new Second Edition keeps pace with the latest drug discoveries and new therapeutic agents -- a task that challenges even specialists in the field. Contributions from many of the leading investigators in cardiovascular pathophysiology and drug development This timely second edition, primarily oriented toward specific drugs and drug classes, is co-edited and co-authored by three distinguished physician-scientists with important research accomplishments in cardiovascular pharmacology and pathophysiology. They provide you with: An understanding of all presently available cardiovascular agents The scientific basis behind every pharmacotherapy advance Hands-on discussions of how to utilize specific drugs for treatment of various cardiovascular disorders and for the prevention of disease Information about recently approved drugs that were only pharmacologic concepts in the previous edition Detailed discussion of drugs in development and potential drug targets for innovative drug discovery – outgrowths of advances in knowledge of receptor and ion channel biology, cell growth, neurohumoral control, biochemistry and pathophysiology More Significant Features of the Second Edition New section on New Drug Classes in Development keeps you abreast of this fast-evolving therapeutic area Special Topics section provides additional information on drug-drug interactions, the use of cardiovascular drugs in children, the treatment of peripheral vascular disease, complementary medicine, and quality of life issues Appendices provide you with practical, hands-on information on drug utilization in clinical practice


Cardiovascular Pharmacotherapeutics

Cardiovascular Pharmacotherapeutics
Author: William H. Frishman
Publisher: Cardiotext Pub
Total Pages: 775
Release: 2011
Genre: Medical
ISBN: 9780979016431

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A critically acclaimed classic reference now in its third edition, Cardiovascular Pharmacotherapeutics provides current information regarding the contemporary use of all available cardiovascular medications for adults and children. Strongly emphasizing the scientific rationale behind the use of such therapies in cardiac disease, it discusses new drugs and novel compounds that are under development and may emerge as the cardiac therapies of the future. This edition also addresses special considerations for drug therapy use in the elderly, during pregnancy, and in those with hepatic or renal disease. A generous assortment of tables, figures, and appendices guides readers in their investigations of each drug group and various disease states.


Drugs for the Heart

Drugs for the Heart
Author: Lionel H. Opie
Publisher: Saunders
Total Pages: 0
Release: 2009
Genre: Medical
ISBN: 9781416061588

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Drugs for the Heart presents highly portable, up-to-date information on every drug class used to treat cardiovascular disease. Drs. Lionel H. Opie and Bernard J. Gersh put the latest dosages, interactions, indications and contraindications, side effects, and more at your fingertips, equipping you to make effective clinical decisions on behalf of your patients Quickly check when to use each drug for any condition with the popular "Which Drug for Which Disease" chapter. Get expert advice from the practice-proven experience of two well-known editors who represent the best possible combination of clinical and research expertise in cardiovascular therapeutics. Expedite your reference with summaries of each drug class at the end of chapters. Carry it with you anywhere thanks to a highly compact, pocket-sized format. Navigate the latest pharmacologic advances through coverage of the newest drugs and drug classes, as well as all the latest clinical trial results and evidence used to treat heart disease. Effectively manage comorbid diseases. Apply international insights into cardiac drugs, thanks to new global contributors. Visualize key pharmacologic and physiologic actions thanks to dynamic new full-color drawings. Access the complete contents online at Expert Consult, with regular online updates posted by leading cardiologist, Dr. Opie. Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. If the next edition is published less than one year after your purchase, you will be entitled to online access for one year from your date of purchase. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should access to the web site be discontinued.


Drugs for the Heart E-Book

Drugs for the Heart E-Book
Author: Lionel H. Opie
Publisher: Elsevier Health Sciences
Total Pages: 513
Release: 2011-12-01
Genre: Medical
ISBN: 1455740896

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The new edition of this market-leading cardiac drug resource equips you with the latest advances in cardiovascular pharmacology, one of the most rapidly changing areas of medicine. It not only offers in-depth information on all of the drug classes used to treat heart disease, but also covers new drug classes, drug use for single and multiple problem management, and more. Dynamic full-color drawings illustrate key pharmacological and physiological actions, and a user-friendly organization directs you to the information you need. An increased emphasis on the practical use of drugs saves you valuable time in researching relevant information. Features the practice-proven experience of two well-known editors who represent the best possible combination of clinical and research expertise in cardiovascular therapeutics. Offers easy-to-access, useful information on when to use each drug—and for what conditions—in a chapter entitled “Which Drug for Which Disease. Discusses the management of single diseases and multiple comorbidities. Summarizes each drug class at the end of chapters to expedite reference. Incorporates all-new drugs, preparations, and clinical trial data in each chapter, equipping you to make the most up-to-date, informed clinical decisions. Offers expanded coverage of comorbid diseases through new chapters on metabolic syndrome, hyperglycemia, and diabetes. Features an increased emphasis on the practical use of drugs through highlighted sections and key illustrations, saving you time in searching for relevant information. Presents the work of several new contributors who represent a broad international perspective to equip you with a global view of cardiovascular pharmacology.


Modern Methods of Clinical Investigation

Modern Methods of Clinical Investigation
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 241
Release: 1990-02-01
Genre: Medical
ISBN: 0309042860

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The very rapid pace of advances in biomedical research promises us a wide range of new drugs, medical devices, and clinical procedures. The extent to which these discoveries will benefit the public, however, depends in large part on the methods we choose for developing and testing them. Modern Methods of Clinical Investigation focuses on strategies for clinical evaluation and their role in uncovering the actual benefits and risks of medical innovation. Essays explore differences in our current systems for evaluating drugs, medical devices, and clinical procedures; health insurance databases as a tool for assessing treatment outcomes; the role of the medical profession, the Food and Drug Administration, and industry in stimulating the use of evaluative methods; and more. This book will be of special interest to policymakers, regulators, executives in the medical industry, clinical researchers, and physicians.


The ESC Handbook on Cardiovascular Pharmacotherapy

The ESC Handbook on Cardiovascular Pharmacotherapy
Author: Juan Carlos Kaski
Publisher: European Society of Cardiology
Total Pages: 961
Release: 2019-05-23
Genre: Medical
ISBN: 0198759932

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The ESC Handbook on Cardiovascular Pharmacotherapy, based on the most recent guidelines in cardiovascular pharmacology, and containing a comprehensive A-Z formulary of common and less commonly used cardiac drugs and drug groups, provides practical and accessible guidance on all areas of drugprescribing.Previously published as Drugs in Cardiology, this new edition has been developed by the ESC Working Group on Cardiovascular Pharmacology. Pharmacology is an integral aspect in almost all disciplines within cardiology and all cardiologists use cardiovascular drugs.Completely updated and aligned with the ESC Clinical Practice Guidelines for prescribing, this handbook is essential reading for consultants, registrars in training, general practitioners, specialist cardiac nurses and cardiovascular pharmacologists.


Principles of Safety Pharmacology

Principles of Safety Pharmacology
Author: Michael K. Pugsley
Publisher: Springer
Total Pages: 477
Release: 2015-06-19
Genre: Medical
ISBN: 366246943X

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This book illustrates, in a comprehensive manner, the most current areas of importance to Safety Pharmacology, a burgeoning unique pharmacological discipline with important ties to academia, industry and regulatory authorities. It provides readers with a definitive collection of topics containing essential information on the latest industry guidelines and overviews current and breakthrough topics in both functional and molecular pharmacology. An additional novelty of the book is that it constitutes academic, pharmaceutical and biotechnology perspectives for Safety Pharmacology issues. Each chapter is written by an expert in the area and includes not only a fundamental background regarding the topic but also detailed descriptions of currently accepted, validated models and methods as well as innovative methodologies used in drug discovery.


Improving and Accelerating Therapeutic Development for Nervous System Disorders

Improving and Accelerating Therapeutic Development for Nervous System Disorders
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 107
Release: 2014-02-06
Genre: Medical
ISBN: 0309292492

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Improving and Accelerating Therapeutic Development for Nervous System Disorders is the summary of a workshop convened by the IOM Forum on Neuroscience and Nervous System Disorders to examine opportunities to accelerate early phases of drug development for nervous system drug discovery. Workshop participants discussed challenges in neuroscience research for enabling faster entry of potential treatments into first-in-human trials, explored how new and emerging tools and technologies may improve the efficiency of research, and considered mechanisms to facilitate a more effective and efficient development pipeline. There are several challenges to the current drug development pipeline for nervous system disorders. The fundamental etiology and pathophysiology of many nervous system disorders are unknown and the brain is inaccessible to study, making it difficult to develop accurate models. Patient heterogeneity is high, disease pathology can occur years to decades before becoming clinically apparent, and diagnostic and treatment biomarkers are lacking. In addition, the lack of validated targets, limitations related to the predictive validity of animal models - the extent to which the model predicts clinical efficacy - and regulatory barriers can also impede translation and drug development for nervous system disorders. Improving and Accelerating Therapeutic Development for Nervous System Disorders identifies avenues for moving directly from cellular models to human trials, minimizing the need for animal models to test efficacy, and discusses the potential benefits and risks of such an approach. This report is a timely discussion of opportunities to improve early drug development with a focus toward preclinical trials.