Cancer Chemoprevention PDF Download
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| Author | : John M. Pezzuto |
| Publisher | : Springer Nature |
| Total Pages | : 639 |
| Release | : 2020-04-03 |
| Genre | : Medical |
| ISBN | : 3030398552 |
Download Natural Products for Cancer Chemoprevention Book in PDF, ePub and Kindle
This book discusses the efficacy of various naturally occurring chemopreventive agents in preventing or delaying cancer. It focuses on the holistic chemopreventive concept, demonstrating the relevant response is the combined effect of a series of compounds that alone have been shown to have some effect in different experimental models. Written by leading experts in the field, the contributions provide details of research on various chemopreventive agents. Offering insights into the unique molecular targets and mechanisms, safety issues, molecular efficacy, and occurrence in nature of these compounds, the book is a valuable resource for all scientists working in biomedicine, and specifically in cancer research.
| Author | : Robert C. Bast, Jr. |
| Publisher | : John Wiley & Sons |
| Total Pages | : 2004 |
| Release | : 2017-03-10 |
| Genre | : Medical |
| ISBN | : 111900084X |
Download Holland-Frei Cancer Medicine Book in PDF, ePub and Kindle
Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
| Author | : Manish Kumar |
| Publisher | : Springer Nature |
| Total Pages | : 344 |
| Release | : 2020-07-20 |
| Genre | : Medical |
| ISBN | : 9811559996 |
Download Pharmacotherapeutic Botanicals for Cancer Chemoprevention Book in PDF, ePub and Kindle
The book presents a comprehensive and up-to-date overview of phytochemicals as efficient cancer therapeutics. Over the last few decades there has been a paradigm shift from conventional cancer therapeutic approaches to alternative and complementary medicinal approaches especially using phytoconstituents from natural products. As such, the book provides an in-depth understanding of phytochemicals targeting diverse signaling pathways involved in cancer along with the evaluation of the cancer modulatory effects of phytochemicals. It also highlights the potential modulatory effect of single nucleotide polymorphisms (SNPs) on the cancer-associated cellular pathways and their interactions with the phytochemicals. Further, it analyzes the drug delivery methods, bioavailability of active components of botanicals, and toxicity of phytochemicals. Lastly, the book elucidates the 3D cell culture and animal models systems to analyze the beneficial effects of phytochemicals in cancer.
| Author | : H.-J. Senn |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 205 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 3642599451 |
Download Chemoprevention of Cancer Book in PDF, ePub and Kindle
Pharmacologic interventions to prevent the evolution of human cancers are still in its infancy, although a good number o- mostly controlled - clinical studies have been performed in the past two decades. However, regarding the partially stagnating therapeutic results of major epithelial cancer types such as breast-, lung-, colon- and ENT-cancer types, the problem of in terference with the evolution of disease at a preclinical level is an intriguing one, and the field seems to develop into one of the fastest growing domaines of modern oncology. This process is fa cilitated by the developments of molecular on co-genetics and the gowing existence of family cancer units, allowing to better identi fy and inform respective high risk groups, thus enabling re searchers and clinicians to more realistically target their chemo preventive efforts to the true populations at risk. On this changing background, the newly formed International Society of Cancer Chemoprevention (ISCaC) together with the Swiss Cancer League and the Interdisciplinary Oncology Center of St. Gallen/Switzerland organized an international Symposium in September 1997, inviting basic researchers, epidemiologists and clinical oncologists of related disciplines to discuss pertinent issues of experimental and clinical chemo- and bio-prevention in a scientific workshop.
| Author | : Gary J. Kelloff |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 537 |
| Release | : 2008-08-17 |
| Genre | : Medical |
| ISBN | : 1592597688 |
Download Cancer Chemoprevention Book in PDF, ePub and Kindle
Despite significant advances in cancer treatment and measures of neoplastic progression, drug effect (or early detection, overall cancer incidence has increased, pharmacodynamic markers), and markers that measure cancer-associated morbidity is considerable, and overall prognosis as well as predict responses to specific therapy. cancer survival has remained relatively flat over the past All these biomarkers have the potential to greatly augment several decades (1,2). However, new technology the development of successful chemoprevention therapies, allowing exploration of signal transduction pathways, but two specific types of biomarkers will have the most identification of cancer-associated genes, and imaging of immediate impact on successful chemopreventive drug tissue architecture and molecular and cellular function is development—those that measure the risk of developing increasing our understanding of carcinogenesis and cancer invasive life-threatening disease, and those whose mo- progression. This knowledge is moving the focus of cancer lation can “reasonably predict” clinical benefit and, therapeutics, including cancer preventive treatments, to therefore, serve as surrogate endpoints for later-occurring drugs that take advantage of cellular control mechanisms clinical disease. Thus far, the biomarker that best measures to selectively suppress cancer progression. these two phenomena is intraepithelial neoplasia (IEN) Carcinogenesis is now visualized as a multifocal, because it is a near obligate precursor to cancer.
| Author | : Gary J. Kelloff |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 998 |
| Release | : 2004-06-04 |
| Genre | : Medical |
| ISBN | : 159259767X |
Download Cancer Chemoprevention Book in PDF, ePub and Kindle
Accompanying CD-ROM in pocket at end of v. 2 contains a compact e-book version of v. 2.
| Author | : Mohammad Fahad Ullah |
| Publisher | : Springer |
| Total Pages | : 376 |
| Release | : 2015-10-06 |
| Genre | : Science |
| ISBN | : 3319214616 |
Download Critical Dietary Factors in Cancer Chemoprevention Book in PDF, ePub and Kindle
This book focuses on the prophylactic potential of diet-derived factors in primary prevention of cancer. It is written by a group of highly reputed experts in the area of dietary agents and cancer chemoprevention. The translational potential of dietary factors from epidemiological, laboratory and clinical studies as prevention strategy in normal and risk populations is highlighted. The work presents options of routine inclusion of specific dietary regimens for prevention as well as therapeutic strategy for better management through adjuvant interventions in cancer treatment.
| Author | : Summya Rashid |
| Publisher | : Springer |
| Total Pages | : 174 |
| Release | : 2017-07-05 |
| Genre | : Medical |
| ISBN | : 9811025797 |
Download Cancer and Chemoprevention: An Overview Book in PDF, ePub and Kindle
This book focuses on the most recent, relevant, comprehensive and significant advances in cancer and chemo prevention. It broadly discusses cancer, its hallmarks and classification, molecular mechanisms of outbreak, contributing factors, role of oxidative stress, inflammatory mediators and evading apoptosis, which leads to the progression of disease. Though modern medicine has left us with no option to treat this deadly disease due to drawbacks associated with conventional treatment – like its non-targeted nature, drug resistance, varied organ toxicities and unaffordability – chemoprevention offers a viable therapeutic window. Given chemoprevention’s importance in the present scenario, the book highlights various chemo preventive strategies currently used in the management of cancer; a selection of novel chemo preventive agents used at clinics and in the pre-clinical stage; hurdles to effective chemoprevention; future prospects and the road ahead. It offers a valuable guide for all graduate students and researchers seeking information on cancer and chemoprevention in general, irrespective of the specific type/pathways involved in its onset.
| Author | : Lee Wattenberg |
| Publisher | : CRC Press |
| Total Pages | : 654 |
| Release | : 1992-08-20 |
| Genre | : Medical |
| ISBN | : 9780849347153 |
Download Cancer Chemoprevention Book in PDF, ePub and Kindle
The ultimate goal of cancer chemoprevention research and development is the identification of pharmaceutical or dietary constituents that will prevent cancer. Cancer Chemoprevention presents the proceedings of a large workshop on cancer chemoprevention that highlights the latest knowledge in the field, in addition to issues and ideas concerning future directions. Retinoids, sulfur compounds, and a large number of many naturally occurring cancer inhibitors in the diet are discussed, including green tea, garlic constituents, citrus fruit oils, and beans and seeds containing protease inhibitors. Compounds that may prevent the formation of carcinogens in food are covered, and the mechanisms by which chemical or dietary agencts produce cancer inhibitors are discussed.
| Author | : Raymond C. Bergan |
| Publisher | : Springer |
| Total Pages | : 336 |
| Release | : 2001 |
| Genre | : Medical |
| ISBN | : |
Download Cancer Chemoprevention Book in PDF, ePub and Kindle
Great advances were made in the pharmacologic-based treatment of cancer in prior decades. However, despite a marked increase in our understanding ofcell and molecular mechanisms underlying the neoplastic process, therapy for advanced disease remains limited. While the reasons for this are many, it is generally accepted that advanced neoplasms contain a relatively large number of genetic and molecularalterations contributingto the maintenanceofthe neoplastic process. Such a situation precludes easy pharmacologic intervention. However, our ability to detect cancer at an earlier stage, coupled with our increased understandingofcarcinogenesis, are propellingboth basic and clinical scientiststo pursue early intervention/chemopreventive approaches. This is based upon the notion that fewer molecularaberrations are presentearlyon inthedisease process. It also takes advantage ofthe fact that advances in both technology, and in the field ofcancer biology, coupled with a heightened vigilance, have increased our ability to detect early disease more readily. The chemopreventive approach is highly attractive for a number ofreasons. First, treatment ofpre-neoplastic, or early neoplastic, lesions would prevent the significant mobility and mortality associated with advanced neoplastic disorders.
