Calcium Signalling In Cancer PDF Download
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| Author | : G. V. Sherbet |
| Publisher | : CRC Press |
| Total Pages | : 385 |
| Release | : 2000-11-29 |
| Genre | : Medical |
| ISBN | : 1420041290 |
Download Calcium Signalling in Cancer Book in PDF, ePub and Kindle
Calcium signalling occupies a preeminent position in the signal transduction system of the cell by virtue of its participation in a wide range of physiological functions together with the biological events associated with genetic expression, cell proliferation and apoptosis, as well as cell differentiation and morphogenesis. It is an important feat
| Author | : Hong-Gang Wang |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 267 |
| Release | : 2013-03-30 |
| Genre | : Medical |
| ISBN | : 1461465613 |
Download Autophagy and Cancer Book in PDF, ePub and Kindle
With the explosion of information on autophagy in cancer, this is an opportune time to speed the efforts to translate our current knowledge about autophagy regulation into better understanding of its role in cancer. This book will cover the latest advances in this area from the basics, such as the molecular machinery for autophagy induction and regulation, up to the current areas of interest such as modulation of autophagy and drug discovery for cancer prevention and treatment. The text will include an explanation on how autophagy can function in both oncogenesis and tumor suppression and a description of its function in tumor development and tumor suppression through its roles in cell survival, cell death, cell growth as well as its influences on inflammation, immunity, DNA damage, oxidative stress, tumor microenvironment, etc. The remaining chapters will cover topics on autophagy and cancer therapy. These pages will serve as a description on how the pro-survival function of autophagy may help cancer cells resist chemotherapy and radiation treatment as well as how the pro-death functions of autophagy may enhance cell death in response to cancer therapy, and how to target autophagy for cancer prevention and therapy − what to target and how to target it.
| Author | : Juliusz Ashot Kozak |
| Publisher | : CRC Press |
| Total Pages | : 343 |
| Release | : 2017-07-14 |
| Genre | : Science |
| ISBN | : 149875273X |
Download Calcium Entry Channels in Non-Excitable Cells Book in PDF, ePub and Kindle
Calcium Entry Channels in Non-Excitable Cells focuses on methods of investigating the structure and function of non-voltage gated calcium channels. Each chapter presents important discoveries in calcium entry pathways, specifically dealing with the molecular identification of store-operated calcium channels which were reviewed by earlier volumes in the Methods in Signal Transduction series. Crystallographic and pharmacological approaches to the study of calcium channels of epithelial cells are also discussed. Calcium ion is a messenger in most cell types. Whereas voltage gated calcium channels have been studied extensively, the non-voltage gated calcium entry channel genes have only been identified relatively recently. The book will fill this important niche.
| Author | : Rosalyn D. Blumenthal |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 234 |
| Release | : 2008-02-01 |
| Genre | : Medical |
| ISBN | : 1592598692 |
Download Chemosensitivity Book in PDF, ePub and Kindle
A state-of-the art collection of readily reproducible laboratory methods for assessing chemosensitivity in vitro and in vivo, and for assessing the parameters that modulate chemosensitivity in individual tumors. Chemosensitivity, Volume 1: In Vitro Assays provides a panel of 16 in vitro measures of chemosensitivity in adherent and non-adherent cells for single agents and combinations of agents. In addition to immunohistochemical and imaging approaches, these assays include clonogenic, colorimetric, fluorometric, and physiological assays. Highlights include image analysis to assess drug sensitivity, high throughput approaches using green fluorescent protein, DIMSCAN (a microcomputer fluorescence-based assay), and the ChemoFx assay used in biotechnology. A companion volume, Volume 2: In Vivo Models, Imaging, and Molecular Regulators, provides protocols for classifying tumors into response categories and customizing chemotherapy regimens to individual patients.
| Author | : Senthilkumar Rajagopal |
| Publisher | : Springer |
| Total Pages | : 106 |
| Release | : 2017-09-28 |
| Genre | : Science |
| ISBN | : 9811051607 |
Download Calcium Signaling: From Physiology to Diseases Book in PDF, ePub and Kindle
This book focuses on disorders of calcium channels and the use of drugs to treat calcium-related disorders and their associated toxicities. In particular, it discusses the role of various natural products and their attributes in preventing problems associated with calcium imbalances. In addition, the book analyzes trends in the processing of natural products using nanotechnology and their implications in calcium-related disorders. Lastly, it explores some of the most promising aspects of research into calcium signalling disorders – which is especially important, given the wide variety of cellular processes that are controlled by calcium ions – and provides a trustworthy source of up-to-date information in this area of research.
| Author | : Lars Kaestner |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 247 |
| Release | : 2012-12-02 |
| Genre | : Medical |
| ISBN | : 3642346170 |
Download Calcium signalling Book in PDF, ePub and Kindle
The book combines general concepts and methods to investigate calcium signalling in cells ranging from molecular biology approaches to manipulation of calcium in living cells. The focus within these methods in on the broad range of fluorescence imaging technology, in particular on optical sectioning techniques and fast image acquisition. In addition to these general guidelines there are application examples in a context beyond calcium signalling in two major fields: investigations of isolated cardiac myocytes and red blood cell related research. While the cellular cardiology section provides snapshots of certain calcium signalling aspects, the red blood cell part presents an overview from the functional identification of calcium-channels to a concept of physiological and pathophysiological relevance.
| Author | : Laszlo Muszbek |
| Publisher | : CRC Press |
| Total Pages | : 297 |
| Release | : 2019-06-04 |
| Genre | : Medical |
| ISBN | : 1000013308 |
Download Hemostasis and Cancer Book in PDF, ePub and Kindle
First Published in 1987: The book is to give insight into the multisided relationship of hemostatic systems and malignancies and to help biomedical scientists and practicing clinicians obtain a better understanding of cancer research.
| Author | : Md. Shahidul Islam |
| Publisher | : Springer Nature |
| Total Pages | : 1110 |
| Release | : 2019-10-23 |
| Genre | : Medical |
| ISBN | : 3030124576 |
Download Calcium Signaling Book in PDF, ePub and Kindle
This volume contains a unique selection of chapters covering a wealth of contemporary topics in this ubiquitous and diverse system of cell signaling. It offers much more than the accessibility and authority of a primary text book, exploring topics ranging from the fundamental aspects of calcium signaling to its varied clinical implications. It presents comprehensive discussion of cutting-edge research alongside detailed analysis of critical issues, at the same time as setting out testable hypotheses that point the way to future scientific endeavors. The contributions feature material on theoretical and methodological topics as well as related subjects including mathematical modeling and simulations. They examine calcium signaling in a host of contexts, from mammalian cells to bacteria, fruit fly and zebrafish. With much of interest to newcomers to the field as well as seasoned experts, this new publication is both wide-ranging and authoritative. The chapter “Calcium Signaling: From Basic to Bedside” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
| Author | : Mohammed M. Sayeed |
| Publisher | : CRC Press |
| Total Pages | : 186 |
| Release | : 1989-05-31 |
| Genre | : Science |
| ISBN | : 9780849340611 |
Download Cellular Pathophysiology Book in PDF, ePub and Kindle
In recent years, there has been increased research on cellular pathophysiology in animal and tissue models simulating human disease processes. The result of this research, which has been carried out primarily by physiologists, pharmacologists, biochemists, anatomists, pathologists, and clinicians, is now presented in this forum. A better understanding of how cellular, subcellular and molecular mechanisms initiate and progressively intensify organic/systemic disease processes is important in the development of rational therapies against these disease processes.
| Author | : |
| Publisher | : BoD – Books on Demand |
| Total Pages | : 204 |
| Release | : 2018-10-24 |
| Genre | : Science |
| ISBN | : 1789842492 |
Download Calcium and Signal Transduction Book in PDF, ePub and Kindle
Since the development of microelectronic clamping methodology and fluorescent indicators for direct measurement of dynamic intracellular calcium transients, our understanding of biological signal transduction has progressed dramatically since the 1980s. Calcium is a universal signal in biology that modulates gene expression, transmitter and hormone release, muscular movement, and even "programmed" cell death. This book represents a compilation of chapters from a diverse set of expert biologists throughout the world who have conducted research in the general area of calcium signaling in organisms ranging from bacteria to humans. In accord with priorities of resolving human disease, the reader will also benefit from learning calcium's role in cellular signaling pathology relating to acute or chronic conditions such as vomiting, sepsis, obesity, hypertension, and cancer.
