Calcium Signaling From Physiology To Diseases PDF Download
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| Author | : Senthilkumar Rajagopal |
| Publisher | : Springer |
| Total Pages | : 106 |
| Release | : 2017-09-28 |
| Genre | : Science |
| ISBN | : 9811051607 |
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This book focuses on disorders of calcium channels and the use of drugs to treat calcium-related disorders and their associated toxicities. In particular, it discusses the role of various natural products and their attributes in preventing problems associated with calcium imbalances. In addition, the book analyzes trends in the processing of natural products using nanotechnology and their implications in calcium-related disorders. Lastly, it explores some of the most promising aspects of research into calcium signalling disorders – which is especially important, given the wide variety of cellular processes that are controlled by calcium ions – and provides a trustworthy source of up-to-date information in this area of research.
| Author | : Ernesto Carafoli |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 591 |
| Release | : 2007-09-29 |
| Genre | : Medical |
| ISBN | : 1402061919 |
Download Calcium Signalling and Disease Book in PDF, ePub and Kindle
Authors highlight several promising discoveries in the field of calcium signaling that provide new information about both genetic and acquired pathologies. Their discussions will give you new insights into the underlying causes of congenital and acquired diseases and point the way to new, even more promising research and therapies.
| Author | : Roman Brown |
| Publisher | : Murphy & Moore Publishing |
| Total Pages | : 240 |
| Release | : 2021-11-16 |
| Genre | : Science |
| ISBN | : 9781639870912 |
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The usage of calcium ions to drive intracellular processes and for communication is called calcium signaling. It is generally a step in signal transduction. Calcium can also function as second messengers wherein they fulfill tasks such as neuronal transmission, cellular motility, muscle contraction and cell growth. Within neurons, concomitant rise in mitochondrial and cytosolic calcium ions are integral to the synchronization of mitochondrial energy metabolism and neuronal electrical activity. However, high level of cytoplasmic calcium ion can cause the cell apostosis. The influx of calcium ions also triggers the development of the oocyte in numerous species. In the case of fish and echinoderms, this influx takes place as a single rise in concentration, while in mammals, the concentration oscillates. This book provides comprehensive insights into the research on calcium signaling. It presents researches and studies performed by experts across the globe. This book will serve as a reference to a broad spectrum of readers.
| Author | : Francesco Moccia |
| Publisher | : MDPI |
| Total Pages | : 463 |
| Release | : 2019-01-21 |
| Genre | : Biochemistry |
| ISBN | : 3038975370 |
Download Calcium Signaling in Human Health and Diseases Book in PDF, ePub and Kindle
This book is a printed edition of the Special Issue "Calcium Signaling in Human Health and Diseases" that was published in IJMS
| Author | : Lars Kaestner |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 247 |
| Release | : 2012-12-02 |
| Genre | : Medical |
| ISBN | : 3642346170 |
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The book combines general concepts and methods to investigate calcium signalling in cells ranging from molecular biology approaches to manipulation of calcium in living cells. The focus within these methods in on the broad range of fluorescence imaging technology, in particular on optical sectioning techniques and fast image acquisition. In addition to these general guidelines there are application examples in a context beyond calcium signalling in two major fields: investigations of isolated cardiac myocytes and red blood cell related research. While the cellular cardiology section provides snapshots of certain calcium signalling aspects, the red blood cell part presents an overview from the functional identification of calcium-channels to a concept of physiological and pathophysiological relevance.
| Author | : Francesco Moccia |
| Publisher | : |
| Total Pages | : 1 |
| Release | : 2019 |
| Genre | : Electronic books |
| ISBN | : 9783038975380 |
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Intracellular Ca2+ signaling is witnessing an amazing resurgence of interest. In addition to traditional Ca2+ aficionados, an astonishing (and growing) number of colleagues from all around the world have started to devote a large part of their research to gain insights into the role of Ca2+ signaling in health and disease. This is why calcium ions interact with virtually every signal transduction pathway not only in mammalian cells, but also across the phylogenetic tree, thereby, driving or modulating most, if not all, cellular functions, ranging from fertilization to apoptosis, passing through learning and memory, cardiac contractility, and immune response. This book gathers a collection of original research articles and reviews by a number of renowned experts who aim to present the state of the art of many pathophysiological aspects of intracellular Ca2+ signaling, such as embryonic development, immune response, extracellular Ca2+ signaling, neoplastic transformation, muscle hypertrophy, pulmonary inflammation, and P2X receptor gating.
| Author | : Md. Shahidul Islam |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 1254 |
| Release | : 2012-04-19 |
| Genre | : Medical |
| ISBN | : 9400728875 |
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Calcium signaling contains a unique selection of chapters that cover a wide range of contemporary topics in this ubiquitous and diverse system of cell signaling. This book has the flavor of a primary text book, but it is much more than that. It covers topics ranging from the fundamental aspects of calcium signaling to its clinical implications, in a thoughtful and comprehensive way. It discusses cutting edge researches, and critical issues at depth, and it presents many testable hypotheses for future research. It includes the theoretical and the methodological topics as well as topics related to mathematical modeling, and simulations. If you want to read about calcium signaling in different mammalian cells, oocytes, Zebrafishes, and even in plants, in one and the same book, then this book will not disappoint you. From the beginners to the experts in the field of calcium signaling, everybody will find something useful in this very timely book.
| Author | : Norbert Weiss |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 725 |
| Release | : 2013-11-09 |
| Genre | : Medical |
| ISBN | : 3642402828 |
Download Pathologies of Calcium Channels Book in PDF, ePub and Kindle
Calcium ions represent Mother Nature’s ‘ion-of-choice’ for regulating fundamental physiological functions, as they initiate a new life at the time of fertilization and guide subsequent developmental and physiological functions of the human body. Calcium channels, which act as gated pathways for the movement of calcium ions across the membranes, play a central part in the initiation of calcium signals, and defects in calcium channel function have been found to result in a plethora of human diseases, referred to as the calcium channelopathies. Pathologies of Calcium Channels brings together leading international experts to discuss our current understanding of human diseases associated with the various calcium channels, from their molecular basis to potential future therapeutic targeting of calcium channels.
| Author | : Martin D. Bootman |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2012 |
| Genre | : Calcium |
| ISBN | : 9780879699031 |
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Calcium ions play a critical role in signaling in a wide variety of cells and tissues, including muscle, immune cells, neurons, the liver, and oocytes. They can enter the cytoplasm from the extracellular environment or from intracellular stores and control the activity of numerous enzymes, other signaling molecules, transcription factors, and cytoskeletal components. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology explores the channels and pumps that transport calcium between different compartments and the regulation of calcium fluxes. The contributors discuss calcium buffers and sensors and how these produce distinct spatiotemporal calcium signals in different circumstances. Including discussions of calcium signaling during development and normal physiology, as well as perturbed signaling in diseases such as diabetes, neurodegeneration, and atherosclerosis, the volume is an indispensable reference for biochemists, cell and developmental biologists, and physiologists seeking a comprehensive treatment of calcium biology.
| Author | : G. V. Sherbet |
| Publisher | : CRC Press |
| Total Pages | : 384 |
| Release | : 2000-11-29 |
| Genre | : Science |
| ISBN | : 9780849309427 |
Download Calcium Signalling in Cancer Book in PDF, ePub and Kindle
Calcium signalling occupies a preeminent position in the signal transduction system of the cell by virtue of its participation in a wide range of physiological functions together with the biological events associated with genetic expression, cell proliferation and apoptosis, as well as cell differentiation and morphogenesis. It is an important feature of cell adhesion and motility; the integrity of the calcium binding proteins themselves is a basic requirement of normal biological function. In fact, the deregulation of calcium signaling is now regarded as the primary event in the pathogenesis, growth, invasion, and secondary spread of cancer. Calcium Signalling in Cancer is a concise up-to-date treatise on the transduction signals induced by calcium that considers how alterations in this calcium-dependent signal transduction pathway are related to a number of human diseases, especially neoplastic transformation. This authoritative text examines a broad range of topics-from mechanisms and significance of calcium homeostasis for normal cell function to calcium signalling pathways and the transduction of the calcium signal, especially in proliferation, cell motility, cancer invasion,, and metastasis. Clearly organized, it covers all aspects of the subject including specific sections on the regulation of the genes whose products are required for signal transduction by calcium, such as Alzheimer's disease, Darier's disease, Duchenne and limb girdle dystrophies, psoriasis and some forms of ichthyosis, and cancer associated retinopathy. With an extensive bibliography and over 2,500 references, Calcium Signalling in Cancer is an invaluable reference source.
