C H And C X Bond Functionalization PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download C H And C X Bond Functionalization PDF full book. Access full book title C H And C X Bond Functionalization.
| Author | : Xavi Ribas |
| Publisher | : Royal Society of Chemistry |
| Total Pages | : 489 |
| Release | : 2013-05-24 |
| Genre | : Science |
| ISBN | : 1849737169 |
Download C-H and C-X Bond Functionalization Book in PDF, ePub and Kindle
Cross-coupling reactions involving C-H and C-X bond functionalisation are commonplace in natural product synthesis and natural products, therapeutic agents, biological probes, and advanced materials. Much attention has been given to understanding the mechanistic strategies used to achieve this, making this a hot topic in recent years. In this edited book, contributions from across the globe examine these strategies, with a particular focus on palladium and copper, as well as iron – an emerging element in this field. Reviewing the recent literature, the book presents an in-depth understanding of the field, guiding the reader to achieving the best synthetic strategies for aromatic functionalisation. Organic and Organometallic chemists, as well as natural product and pharmaceutical scientists, will find this an essential guide to a major transformation currently underway in synthetic chemistry.
| Author | : Xavi Ribas |
| Publisher | : Royal Society of Chemistry |
| Total Pages | : 489 |
| Release | : 2013 |
| Genre | : Science |
| ISBN | : 1849735700 |
Download C-H and C-X Bond Functionalization Book in PDF, ePub and Kindle
Cross-coupling reactions involving C-H and C-X bond functionalisation are commonplace in natural product synthesis and natural products, therapeutic agents, biological probes, and advanced materials. Much attention has been given to understanding the mechanistic strategies used to achieve this, making this a hot topic in recent years. In this edited book, contributions from across the globe examine these strategies, with a particular focus on palladium and copper, as well as iron û an emerging element in this field. Reviewing the recent literature, the book presents an in-depth understanding of the field, guiding the reader to achieving the best synthetic strategies for aromatic functionalisation. Organic and Organometallic chemists, as well as natural product and pharmaceutical scientists, will find this an essential guide to a major transformation currently underway in synthetic chemistry.
| Author | : Steven Michael Bischof |
| Publisher | : |
| Total Pages | : 846 |
| Release | : 2012 |
| Genre | : Activation (Chemistry) |
| ISBN | : |
Download Developing New Methods to Functionalize C-H Bonds Using a C-H Activation/M-R Functionalization Approach Book in PDF, ePub and Kindle
The conversion of hydrocarbon resources (oil and natural gas) to useful products constitutes a major portion of industrial chemistry; wherein, the products of such processes are utilized in the manufacture of materials, commodity chemicals, and pharmaceuticals. One possible method for overcoming this challenge is the design of new catalysts that operate via the C-H activation reaction coupled to an efficient M-R functionalization using transition metal catalysts. However, very few efficient C-H functionalization catalysts have been reported in the literature. The development of new methods to functionalize M-R intermediates and their coupling to C-H activation may meet this challenge. This thesis presents work focused on two core areas related to C-H bond functionalization, C-H activation and M-R functionalization. C-H activation involves the formation of an activated of metal-carbon intermediate by scission of a hydrocarbon C-H bond. This is followed by functionalization of the incipient metal-carbon intermediate to generate C-X bonds. The concepts related to choosing such a two-step, C-H activation/M-R functionalization, approach are presented in Chapter 1. Following chapters focus on independent study of C-H activation and M-R functionalization reactions, with a final emphasis on combining working M-R functionalization reactions to known C-H activation catalysts to complete the catalytic cycle. Chapter 2 focuses on Baeyer-Villiger and related functionalization reactions of an aryl-rheniumtrioxide complex. Work on M-R functionalization reactions is extended in Chapter 3 with a study on low oxidation state Re-CH3 compounds for oxy-functionalization reactions. Examination of an iridium catalyst that undergoes extraordinarily facile C-H activation and the mechanistic basis for the observed catalytic rates is presented in Chapter 4. Chapter 5 extends our examination on the C-H activation reaction using iridium and rhodium catalysts and finds that both arenes and alkanes are activated. Most significantly, oxy-functionalization of benzene is observed in the presence of Cu II salts using either family of catalysts. Finally, Chapter 6 makes concluding remarks on this work and what lies in store for the future.
| Author | : Arkadi Vigalok |
| Publisher | : Springer |
| Total Pages | : 198 |
| Release | : 2010-06-30 |
| Genre | : Science |
| ISBN | : 3642120733 |
Download C-X Bond Formation Book in PDF, ePub and Kindle
Contents: Kilian Muñiz: Transition Metal Catalyzed Electrophilic Halogenation of C-H bonds in alpha-Position to Carbonyl Groups; Arkadi Vigalok * and Ariela W Kaspi: Late Transition Metal-Mediated Formation of Carbon-Halogen Bonds; Paul Bichler and Jennifer A. Love*: Organometallic Approaches to Carbon-Sulfur Bond Formation; David S. Glueck: Recent Advances in Metal-Catalyzed C-P Bond Formation; Andrei N. Vedernikov: C-O Reductive Elimination from High Valent Pt and Pd Centers; Lukas Hintermann: Recent Developments in Metal-Catalyzed Additions of Oxygen Nucleophiles to Alkenes and Alkynes; Moris S. Eisen: Catalytic C-N, C-O and C-S bond formation promoted by organoactinide complexes.
| Author | : Shu-Li You |
| Publisher | : Royal Society of Chemistry |
| Total Pages | : 433 |
| Release | : 2015-08-13 |
| Genre | : Science |
| ISBN | : 1782621024 |
Download Asymmetric Functionalization of C-H Bonds Book in PDF, ePub and Kindle
Asymmetric C-H direct functionalization reactions are one of the most active and fascinating areas of research in organic chemistry due to their significance in the construction of molecular complexity without pre-activation, and the step economy and atom economy features in potential synthetic application. Distinguishing the reactivity among numerous C–H bonds in one single molecule represents one of the most challenging issues in organic synthesis and requires precise reaction design. As such, this field is now receiving increasing attention from researchers. This book provides the first comprehensive review of this field, summarizing the origin, mechanism, scope and applications of the asymmetric C-H bond functionalization reaction. It covers organocatalytic reactions and transition-metal-catalyzed reactions, as well as asymmetric C-H functionalization reactions not described in other books. Written by a leading expert in this field, the book is ideal for postgraduates and researchers working in organic synthesis, catalysis, and organometallic chemistry.
| Author | : Karen I. Goldberg |
| Publisher | : ACS Symposium |
| Total Pages | : 0 |
| Release | : 2004 |
| Genre | : Science |
| ISBN | : 9780841238497 |
Download Activation and Functionalization of C-H Bonds Book in PDF, ePub and Kindle
Activation and Functionalization of C-H Bonds explores recent developments in the reaction chemistry of solution-phase transition-metal based systems with simple hydrocarbons and with more complex organic molecules. More than 20 internationally leading research groups contributed to this volume, and their chapters cover such topics as fundamental theoretical and mechanistic studies of C-H bond activation by metal complexes, catalytic systems for alkane functionalization, and new applications in synthetic organic chemistry. An introductory chapter offers an overview of stoichiometric and catalytic reactions of C-H bonds with transition metal complexes. The C-H bond is the most widespread linkage in organic chemistry, present in virtually every organic molecule. Unfortunately, C-H bonds are famously resistant to selective chemical transformations. The development of methods for their selective transformations has enormous potential value in fields ranging from the chemistry of fuels (for example, the conversion of methane to methanol) to the synthesis of the most complex organic molecules.
| Author | : Robertus J. M. Klein Gebbink |
| Publisher | : John Wiley & Sons |
| Total Pages | : 709 |
| Release | : 2018-12-31 |
| Genre | : Technology & Engineering |
| ISBN | : 3527699104 |
Download Non-Noble Metal Catalysis Book in PDF, ePub and Kindle
An expert overview of current research, applications, and economic and environmental advantages The study and development of new homogeneous catalysts based on first-row metals (Mn, Fe, Co, Ni, and Cu) has grown significantly due to the economic and environmental advantages that non-noble metals present. Base metals offer reduced cost, greater supply, and lower toxicity levels than noble metals?enabling greater opportunity for scientific investigation and increased development of practical applications. Non-Noble Metal Catalysis provides an authoritative survey of the field, from fundamental concepts and computational methods to industrial applications and reaction classes. Recognized experts in organometallic chemistry and homogeneous catalysis, the authors present a comprehensive overview of the conceptual and practical aspects of non-noble metal catalysts. Examination of topics including non-innocent ligands, proton-coupled electron transfer, and multi-nuclear complexes provide essential background information, while areas such as kinetic lability and lifetimes of intermediates reflect current research and shifting trends in the field. This timely book demonstrates the efficacy of base metal catalysts in the pharmaceutical, fine-chemical, and agrochemical industries, addressing both environmental and economic concerns. Providing essential conceptual and practical exploration, this valuable resource: -Illustrates how unravelling new reactivity patterns can lead to new catalysts and new applications -Highlights the multiple advantages of using non-noble metals in homogenous catalysis -Demonstrates how the availability of non-noble metal catalysis reduces costs and leads to immense savings for the chemical industry -Reveals how non-noble metal catalysis are more sustainable than noble metals such as palladium or platinum Non-Noble Metal Catalysis: Molecular Approaches and Reactions is an indispensable source of up-to-date information for catalytic chemists, organic chemists, industrial chemists, organometallic chemists, and those seeking to broaden their knowledge of catalytic chemistry.
| Author | : Aiwen Lei |
| Publisher | : John Wiley & Sons |
| Total Pages | : 240 |
| Release | : 2016-08-17 |
| Genre | : Technology & Engineering |
| ISBN | : 3527681000 |
Download Oxidative Cross-Coupling Reactions Book in PDF, ePub and Kindle
The first handbook on this emerging field provides a comprehensive overview of transition metal-catalyzed coupling reactions in the presence of an oxidant. Following an introduction to the general concept and mechanism of this reaction class, the team of authors presents chapters on C-C cross-coupling reactions using organometallic partners, C-Heteroatom bond forming reactions via oxidative couplings, and C-H couplings via C-H activation. The text also covers such groundbreaking topics as recent achievements in the fields of C-C and C-X bond formation reactions as well as C-H activation involving oxidative couplings. With its novel and concise approach towards important building blocks in organic chemistry and its focus on synthetic applications, this handbook is of great interest to all synthetic chemists in academia and industry alike.
| Author | : Pierre H. Dixneuf |
| Publisher | : Springer |
| Total Pages | : 264 |
| Release | : 2016-01-06 |
| Genre | : Science |
| ISBN | : 9783319246284 |
Download C-H Bond Activation and Catalytic Functionalization I Book in PDF, ePub and Kindle
The series Topics in Organometallic Chemistry presents critical overviews of research results in organometallic chemistry. As our understanding of organometallic structure, properties and mechanisms increases, new ways are opened for the design of organometallic compounds and reactions tailored to the needs of such diverse areas as organic synthesis, medical research, biology and materials science. Thus the scope of coverage includes a broad range of topics of pure and applied organometallic chemistry, where new breakthroughs are being achieved that are of significance to a larger scientific audience. The individual volumes of Topics in Organometallic Chemistry are thematic. Review articles are generally invited by the volume editors. All chapters from Topics in Organometallic Chemistry are published OnlineFirst with an individual DOI. In references, Topics in Organometallic Chemistry is abbreviated as Top Organomet Chem and cited as a journal.
| Author | : Jin Xie |
| Publisher | : Springer |
| Total Pages | : 91 |
| Release | : 2016-02-29 |
| Genre | : Science |
| ISBN | : 3662494965 |
Download Sustainable C(sp3)-H Bond Functionalization Book in PDF, ePub and Kindle
This book highlights major achievements made in the last five years concerning sustainable C(sp3)-H bond functionalization and offers a promising and emerging tool-kit for organic synthesis. The book is divided into three chapters demonstrating key advances in C(sp3)-H bond functionalization. Chapter 1 reviews transition-metal-catalyzed C(sp3)-H bond functionalization using different directing groups, while Chapter 2 addresses the new methods of transition-metal-catalyzed and metal-free C(sp3)-H bond functionalization without directing groups, in addition to briefly highlighting redox-neutral C(sp3)-H bond functionalization. In closing, Chapter 3 examines visible-light photoredox catalysis, an emerging and highly sustainable C(sp3)-H bond functionalization strategy. The book offers an intriguing and useful reference guide for a broad readership working and/or interested in the fields of organic, organometallic, and green chemistry.
