Brain Insulin Resistance In Neurodevelopmental And Neurodegenerative Disorders Mind The Gap PDF Download
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| Author | : Eugenio Barone |
| Publisher | : Frontiers Media SA |
| Total Pages | : 157 |
| Release | : 2021-10-04 |
| Genre | : Science |
| ISBN | : 2889634574 |
Download Brain Insulin Resistance in Neurodevelopmental and Neurodegenerative Disorders: Mind the Gap! Book in PDF, ePub and Kindle
The failure of insulin signaling – a condition known as insulin resistance – is a key pathological feature of both type 2 diabetes (T2DM, systemic insulin resistance) and Alzheimer’s disease and related dementias (ADRDs, brain insulin resistance) and greatly contribute to their development. Considerable overlap has been identified in the risk factors, comorbidities and putative pathophysiological mechanisms of ADRDs and T2DM, thus proposing AD as type 3 diabetes.
| Author | : Donald L. Schomer |
| Publisher | : Lippincott Williams & Wilkins |
| Total Pages | : 1308 |
| Release | : 2012-10-18 |
| Genre | : Medical |
| ISBN | : 1451153155 |
Download Niedermeyer's Electroencephalography Book in PDF, ePub and Kindle
The leading reference on electroencephalography since 1982, Niedermeyer's Electroencephalography is now in its thoroughly updated Sixth Edition. An international group of experts provides comprehensive coverage of the neurophysiologic and technical aspects of EEG, evoked potentials, and magnetoencephalography, as well as the clinical applications of these studies in neonates, infants, children, adults, and older adults. This edition's new lead editor, Donald Schomer, MD, has updated the technical information and added a major new chapter on artifacts. Other highlights include complete coverage of EEG in the intensive care unit and new chapters on integrating other recording devices with EEG; transcranial electrical and magnetic stimulation; EEG/TMS in evaluation of cognitive and mood disorders; and sleep in premature infants, children and adolescents, and the elderly. A companion website includes fully searchable text and image bank.
| Author | : Sudhir Kumar |
| Publisher | : Pergamon |
| Total Pages | : 642 |
| Release | : 1980 |
| Genre | : Medical |
| ISBN | : |
Download Biochemistry of Brain Book in PDF, ePub and Kindle
Biochemistry of Brain is a collection of articles dealing with the developments in the biochemistry of the brain. This book gives a comprehensive and critical discussion of important developments in studies concerning the above subject. This text discusses the structure, function, and metabolism of glycosphingolipids, which are related to the study of sphingolipid storage diseases. Inborn defects of metabolism are found in Gaucher's and Fabry's disease, which are characterized by lipid accumulation in the brain. Another paper reviews the chemical and genetics of critically lysosomal hydrolase ...
| Author | : |
| Publisher | : Elsevier |
| Total Pages | : 570 |
| Release | : 2002-11-04 |
| Genre | : Medical |
| ISBN | : 0080491596 |
Download Glucose Metabolism in the Brain Book in PDF, ePub and Kindle
Regulation of glucose at the biochemical level affects every area of the brain, and has impact from cellular to behavioral brain function. It plays an important role in diseases such as diabetes, stroke, schizophrenia and drug abuse as well as in normal and dysfunctional memory and cognition. This volume represents a thorough examination of all the major issues that are relevant to glucose metabolism by brain cells in relation to disease, combining basic research and clinical findings in a single, indispensable reference. Serves as an essential reference on glucose metabolism in the brain Presents authoritative accounts by leading researchers in the field Includes thorough reviews with provocative sections on future directions
| Author | : Paul J. Harrison |
| Publisher | : |
| Total Pages | : 402 |
| Release | : 2000-08-24 |
| Genre | : Medical |
| ISBN | : |
Download The Neuropathology of Schizophrenia Book in PDF, ePub and Kindle
What is schizophrenia? This is one of the most controversial questions in psychiatry and mental health research; however, in the last twenty years, there have been significant advances in our understanding of the topic. This book provides a balanced, comprehensive and up-to-date overview of the neuropathology of schizophrenia and its interpretation, covering the latest evidence derived from all fields of research, from brain scans to microscopy. The authors include many of the foremost international authorities in this rapidly developing field.
| Author | : Institute of Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 358 |
| Release | : 2008-03-12 |
| Genre | : Medical |
| ISBN | : 0309108810 |
Download Autism and the Environment Book in PDF, ePub and Kindle
Autism spectrum disorders (ASD) constitute a major public health problem, affecting one in every 150 children and their families. Unfortunately, there is little understanding of the causes of ASD, and, despite their broad societal impact, many people believe that the overall research program for autism is incomplete, particularly as it relates to the role of environmental factors. The Institute of Medicine's Forum on Neuroscience and Nervous System Disorders, in response to a request from the U.S. Secretary of Health and Human Services, hosted a workshop called "Autism and the Environment: Challenges and Opportunities for Research." The focus was on improving the understanding of the ways in which environmental factors such as chemicals, infectious agents, or physiological or psychological stress can affect the development of the brain. Autism and the Environment documents the concerted effort which brought together the key public and private stakeholders to discuss potential ways to improve the understanding of the ways that environmental factors may affect ASD. The presentations and discussions from the workshop that are described in this book identify a number of promising directions for research on the possible role of different environmental agents in the etiology of autism.
| Author | : K. Whaley |
| Publisher | : Springer |
| Total Pages | : 0 |
| Release | : 2012-10-29 |
| Genre | : Medical |
| ISBN | : 9789401049818 |
Download Complement in Health and Disease Book in PDF, ePub and Kindle
Since the first edition of Complement in Health and Disease was published in 1986, significant advances have been made. The cDNAs for all of the components and some of the receptors have been cloned and sequenced. The chromosomal localization and the structural organization of a number of these genes have now been determined. These advances are now facilitating research into the structure of the complement proteins, the nature of the complement deficiency syndromes, the regulation of complement gene expression and the role of complement in different diseases. This edition contains contributions from both basic and clinical scientists in a format which we hope will appeal to both immunologists and physicians who wish to know more about this fascinating and important host defence system. The introductory chapter by John Weiler presents a historical background to research on the complement system and describes the biochemical events occurring during activation of the system. In Chapter 2 Alastair Dodds and Tony Day discuss the phylogeny and evolution of the complement system. The techniques of protein chemistry and molecular biology have provided powerful insights into the modular structure of complement proteins and the evolution of the complement system. The structure and organisation of the complement genes is described in Chapter 3 by Ken Reid and Duncan Campbell. This chapter describes the modular structure of the complement proteins and some of the mutations which are responsible for deficiencies of individual components.
| Author | : Patrick D. McGorry |
| Publisher | : Cambridge University Press |
| Total Pages | : 301 |
| Release | : 2019-08-29 |
| Genre | : Medical |
| ISBN | : 1108718841 |
Download Clinical Staging in Psychiatry Book in PDF, ePub and Kindle
Clinical staging is a solution to transform psychiatric diagnosis and improve mental health outcomes.
| Author | : Robert Howard |
| Publisher | : Routledge |
| Total Pages | : 296 |
| Release | : 1999 |
| Genre | : Medical |
| ISBN | : |
Download Late Onset Schizophrenia Book in PDF, ePub and Kindle
Schizophrenia, which starts in middle age or late life, has been described as 'the darkest area of psychiatry.' It is certainly controversial, with much disagreement about cut-off ages, diagnostic criteria and nomenclature. The contributors to this unique and very important book represent views from Europe and North America as well as Australia, Japan, and Nepal; they come from backgrounds of clinical practice and research. The contributors and editors were motivated by common aims: to review current international knowledge about late onset schizophrenia, to debate issues of heterogenity, gender, brain maturation and aging, putative structural and functional cerebral substrates for psychosis, to reach consensus on diagnosis and terminology, and to future research directions. The resulting book is an unqualified success which as well as being invaluable in old age psychiatry, sheds light on all aspects of schizophrenia treatment and research.
| Author | : J.W.G. Jacobs |
| Publisher | : IOS Press |
| Total Pages | : 370 |
| Release | : 2018-08-14 |
| Genre | : Medical |
| ISBN | : 1614998787 |
Download Ehlers-Danlos Syndrome: A Multidisciplinary Approach Book in PDF, ePub and Kindle
Generalized hypermobility has been known since ancient times, and a clinical description of Ehlers-Danlos syndrome (EDS) is said to have first been recorded by Hippocrates in 400 BC. Hypermobility syndromes occur frequently, but the wide spectrum of possible symptoms, coupled with a relative lack of awareness and recognition, are the reason that they are frequently not recognized, or remain undiagnosed. This book is an international, multidisciplinary guide to hypermobility syndromes, and EDS in particular. It aims to create better awareness of hypermobility syndromes among health professionals, including medical specialists, and to be a guide to the management of such syndromes for patients and practitioners. It is intended for use in daily clinical practice rather than as a reference book for research or the latest developments, and has been written to be understandable for any healthcare worker or educated patient without compromise to the scientific content. The book is organized as follows: chapters on classifications and genetics are followed by chapters on individual types, organ (system) manifestations and complications, and finally ethics and therapeutic strategies, with an appendix on surgery and the precautions which should attend it. A special effort has been made to take account of the perspective of the patient; two of the editors have EDS. The book will be of interest to patients with hypermobility syndromes and their families, as well as to all those healthcare practitioners who may encounter such syndromes in the course of their work.
