Brain Imaging In Substance Abuse PDF Download
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| Author | : Marc J. Kaufman |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 455 |
| Release | : 2000-09-29 |
| Genre | : Medical |
| ISBN | : 1592590217 |
Download Brain Imaging in Substance Abuse Book in PDF, ePub and Kindle
The last two decades have seen prodigious growth in the application of brain imaging methods to questions of substance abuse and addiction. Despite considerable advances in our understanding of the central effects of drugs provided by preclinical data, relatively little direct evidence was known of how substances of abuse affect the brain and other eNS processes in humans. Brain imaging techniques have allowed access to the human brain and enabled the asking of questions never before imagined. The positron emission tomography (PET) data ofVolkow and her colleagues in the late 1980s, showing the uptake and time course of cocaine's binding in the human brain, revealed for the first time the distinct sites of action of this drug. This work was extremely important because it showed clearly, through imaging a drug in the brain of a living human, that the time course of its action paralleled the behavioral state of "high. " This study marked a turning point in our understanding of drug-brain-behav ior interactions in humans. Many more investigations of drug effects on the structure and function of the human brain were soon to follow, leading to much better insights into brain systems. Brain imaging allowed for the direct assessment of structural and functional anatomy, biology, and chemistry in substance abusers.
| Author | : Philip Seeman |
| Publisher | : Elsevier |
| Total Pages | : 534 |
| Release | : 2013-11-15 |
| Genre | : Science |
| ISBN | : 012418684X |
Download Imaging of the Human Brain in Health and Disease Book in PDF, ePub and Kindle
Brain imaging technology remains at the forefront of advances in both our understanding of the brain and our ability to diagnose and treat brain disease and disorders. Imaging of the Human Brain in Health and Disease examines the localization of neurotransmitter receptors in the nervous system of normal, healthy humans and compares that with humans who are suffering from various neurologic diseases. Opening chapters introduce the basic science of imaging neurotransmitters, including sigma, acetylcholine, opioid, and dopamine receptors. Imaging the healthy and diseased brain includes brain imaging of anger, pain, autism, the release of dopamine, the impact of cannabinoids, and Alzheimer's disease. This book is a valuable companion to a wide range of scholars, students, and researchers in neuroscience, clinical neurology, and psychiatry, and provides a detailed introduction to the application of advanced imaging to the treatment of brain disorders and disease. A focused introduction to imaging healthy and diseased brains Focuses on the primary neurotransmitter release Includes sigma, acetylcholine, opioid, and dopamine receptors Presents the imaging of healthy and diseased brains via anger, pain, autism, and Alzheimer's disease
| Author | : Bryon Adinoff |
| Publisher | : John Wiley & Sons |
| Total Pages | : 539 |
| Release | : 2011-11-02 |
| Genre | : Medical |
| ISBN | : 1119972701 |
Download Neuroimaging in Addiction Book in PDF, ePub and Kindle
Neuroimaging in Addiction presents an up-to-date, comprehensive review of the functional and structural imaging human studies that have greatly advanced our understanding of this complex disorder. Approaching addiction from a conceptual rather than a substance-specific perspective, this book integrates broad neuropsychological constructs that consider addiction as a neuroplastic process with genetic, developmental, and substance-induced contributions. The internationally recognized contributors to this volume are leaders in clinical imaging with expertise that spans the addiction spectrum. Following a general introduction, an overview of neural circuitry and modern non-invasive imaging techniques provides the framework for subsequent chapters on reward salience, craving, stress, impulsivity and cognition. Additional topics include the use of neuroimaging for the assessment of acute drug effects, drug-induced neurotoxicity, non-substance addictive behaviors, and the application of imaging genetics to identify unique intermediate phenotypes. The book concludes with an exploration of the future promise for functional imaging as guide to the diagnosis and treatment of addictive disorders. Scientists and clinicians will find the material in this volume invaluable in their work towards understanding the addicted brain, with the overall goal of improved prevention and treatment outcomes for patients. Features a Foreword by Edythe London, Director of the Center for Addictive Behaviors, University of California at Los Angeles.
| Author | : Cameron S. Carter |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 395 |
| Release | : 2011-11-04 |
| Genre | : Medical |
| ISBN | : 3642287115 |
Download Brain Imaging in Behavioral Neuroscience Book in PDF, ePub and Kindle
This volume highlights the remarkable new developments in brain imaging, including those that apply magnetic resonance imaging (MRI) and Positron Emission Tomography (PET), that allow us to non invasively study the living human brain in health and in disease. These technological advances have allowed us to obtain new and powerful insights into the structure and function of the healthy brain as it develops across the life cycle, as well as the molecular make up of brain systems and circuits as they develop and change with age. New brain imaging technologies have also given us new insights into the causes of many common brain disorders, including ADHD, schizophrenia, depression and Alzheimer’s disease, which collectively affect a large segment of the population. These new insights have major implications for understanding and treating these brain disorders, and are providing clinicians with the first ever set of biomarkers that can be used to guide diagnosis and monitor treatment effects. The advances in brain imaging over the last 20 years, summarized in this volume, represent a major advance in modern biomedical sciences.
| Author | : Louis Teresi, MD |
| Publisher | : Author House |
| Total Pages | : 311 |
| Release | : 2011-10 |
| Genre | : Medical |
| ISBN | : 1463444842 |
Download Hijacking the Brain Book in PDF, ePub and Kindle
Hijacking the Brain provides the first-ever scientific explanation for the success of Twelve-Step programs. Hijacking the Brain examines data provided by recent rapid growth in the fields of neuroscience, neuroimaging, psychology, sociobiology and interpersonal neurobiology that have given us new, dramatic insights into the neural and hormonal correlates of stress and addiction, cognitive decline with addiction, as well as for the relative success of Twelve-Step Programs of recovery. Addiction is recognized by experts as an organic brain disease, and most experts promote Twelve-Step programs (AA, NA, CA, etc.) which invoke a 'spiritual solution' for recovery. To date, no one has described why these programs work. 'Hijack' tells us why. In 'Hijack, ' the role of 'working The Steps' for reducing stress and becoming emotionally centered is discussed in depth. A full chapter is devoted to the rewarding and comforting physiology of meditation and the spiritual experience. The author uses examples from animal sociobiology, as well as sophisticated human brain-imaging studies, to demonstrate that empathic socialization and altruism are instinctive and 'naturally rewarding' and, along with Step Work, act as a substitute for the 'synthetic rewards' of drugs of abuse. 'Hijack' does not challenge the Steps or the Traditions of Twelve-Step programs. The sole intention of Hijacking the Brain is to 'connect the dots' between an 'organic brain disease' and a 'spiritual solution' with sound physical, scientific evidence. Avoiding strict scientific language as much as possible, 'Hijack' is written for the layperson and abundantly illustrated.
| Author | : Institute of Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 330 |
| Release | : 1996-11-01 |
| Genre | : Medical |
| ISBN | : 0309055334 |
Download Pathways of Addiction Book in PDF, ePub and Kindle
Drug abuse persists as one of the most costly and contentious problems on the nation's agenda. Pathways of Addiction meets the need for a clear and thoughtful national research agenda that will yield the greatest benefit from today's limited resources. The committee makes its recommendations within the public health framework and incorporates diverse fields of inquiry and a range of policy positions. It examines both the demand and supply aspects of drug abuse. Pathways of Addiction offers a fact-filled, highly readable examination of drug abuse issues in the United States, describing findings and outlining research needs in the areas of behavioral and neurobiological foundations of drug abuse. The book covers the epidemiology and etiology of drug abuse and discusses several of its most troubling health and social consequences, including HIV, violence, and harm to children. Pathways of Addiction looks at the efficacy of different prevention interventions and the many advances that have been made in treatment research in the past 20 years. The book also examines drug treatment in the criminal justice setting and the effectiveness of drug treatment under managed care. The committee advocates systematic study of the laws by which the nation attempts to control drug use and identifies the research questions most germane to public policy. Pathways of Addiction provides a strategic outline for wise investment of the nation's research resources in drug abuse. This comprehensive and accessible volume will have widespread relevanceâ€"to policymakers, researchers, research administrators, foundation decisionmakers, healthcare professionals, faculty and students, and concerned individuals.
| Author | : Office of the Surgeon General |
| Publisher | : Createspace Independent Publishing Platform |
| Total Pages | : 420 |
| Release | : 2017-08-15 |
| Genre | : |
| ISBN | : 9781974580620 |
Download Facing Addiction in America Book in PDF, ePub and Kindle
All across the United States, individuals, families, communities, and health care systems are struggling to cope with substance use, misuse, and substance use disorders. Substance misuse and substance use disorders have devastating effects, disrupt the future plans of too many young people, and all too often, end lives prematurely and tragically. Substance misuse is a major public health challenge and a priority for our nation to address. The effects of substance use are cumulative and costly for our society, placing burdens on workplaces, the health care system, families, states, and communities. The Report discusses opportunities to bring substance use disorder treatment and mainstream health care systems into alignment so that they can address a person's overall health, rather than a substance misuse or a physical health condition alone or in isolation. It also provides suggestions and recommendations for action that everyone-individuals, families, community leaders, law enforcement, health care professionals, policymakers, and researchers-can take to prevent substance misuse and reduce its consequences.
| Author | : Marco Catani |
| Publisher | : Oxford University Press, USA |
| Total Pages | : 533 |
| Release | : 2012-06-14 |
| Genre | : Medical |
| ISBN | : 0199541167 |
Download Atlas of Human Brain Connections Book in PDF, ePub and Kindle
One of the major challenges of modern neuroscience is to define the complex pattern of neural connections that underlie cognition and behaviour. This atlas capitalises on novel diffusion MRI tractography methods to provide a comprehensive overview of connections derived from virtual in vivo tractography dissections of the human brain.
| Author | : Michelle Hampson |
| Publisher | : Academic Press |
| Total Pages | : 366 |
| Release | : 2021-10-09 |
| Genre | : Computers |
| ISBN | : 0128224363 |
Download fMRI Neurofeedback Book in PDF, ePub and Kindle
fMRI Neurofeedback provides a perspective on how the field of functional magnetic resonance imaging (fMRI) neurofeedback has evolved, an introduction to state-of-the-art methods used for fMRI neurofeedback, a review of published neuroscientific and clinical applications, and a discussion of relevant ethical considerations. It gives a view of the ongoing research challenges throughout and provides guidance for researchers new to the field on the practical implementation and design of fMRI neurofeedback protocols. This book is designed to be accessible to all scientists and clinicians interested in conducting fMRI neurofeedback research, addressing the variety of different knowledge gaps that readers may have given their varied backgrounds and avoiding field-specific jargon. The book, therefore, will be suitable for engineers, computer scientists, neuroscientists, psychologists, and physicians working in fMRI neurofeedback. Provides a reference on fMRI neurofeedback covering history, methods, mechanisms, clinical applications, and basic research, as well as ethical considerations Offers contributions from international experts—leading research groups are represented, including from Europe, Japan, Israel, and the United States Includes coverage of data analytic methods, study design, neuroscience mechanisms, and clinical considerations Presents a perspective on future translational development
| Author | : David W. Self |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 392 |
| Release | : 2009-12-18 |
| Genre | : Medical |
| ISBN | : 3642030017 |
Download Behavioral Neuroscience of Drug Addiction Book in PDF, ePub and Kindle
Drug addiction is a chronically relapsing mental illness involving severe motivational disturbances and loss of behavioral control leading to personal dev- tation. The disorder af?icts millions of people, often co-occurring with other mental illnesses with enormous social and economic costs to society. Several decades of research have established that drugs of abuse hijack the brain’s natural reward substrates, and that chronic drug use causes aberrant alterations in these rewa- processing systems. Such aberrations may be demonstrated at the cellular, neu- transmitter, and regional levels of information processing using either animal models or neuroimaging in humans following chronic drug exposure. Behaviorally, these neural aberrations manifest as exaggerated, altered or dysfunctional expr- sion of learned behavioral responses related to the pursuit of drug rewards, or to environmental factors that precipitate craving and relapse during periods of drug withdrawal. Current research efforts are aimed at understanding the associative and causal relationships between these neurobiological and behavioral events, such that treatment options will ultimately employ therapeutic amelioration of neural de?cits and restoration of normal brain processing to promote efforts to abstain from further drug use. The Behavioral Neuroscience of Drug Addiction, part of the Springer series on Current Topics in Behavioral Neurosciences, contains scholarly reviews by noted experts on multiple topics from both basic and clinical neuroscience ?elds.
