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Bone Research in Biomechanics

Bone Research in Biomechanics
Author: G. Lowet
Publisher: IOS Press
Total Pages: 234
Release: 1997
Genre: Biomechanics
ISBN: 9789051993271

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This book focuses on the structure of bone, and its consequences for the mechanical behaviour of the bone structure. The first part of this book focuses on the development of models to predict the adaptation of bone due to changes on the mechanical loading situation (such as provoked by an implant). But far more important than the computer power presently available, the incorporation of knowledge on the biological processes have led to new kinds of models. Next to the development of models itself, the issue of model validation though comparison with clinical data is a main issue addressed in the papers of this symposium. The second part, dealing with the relationship between bone architecture and competence of bone, focuses on the morphology of trabecular bone structure. This work is mainly carried out in the context of research on osteoporosis, and look for the relation between bone structure and fracture risk. The last part is devoted to ultrasound research in bone biomechanics. Several methods have been described for the in vitro and in vivo measurement of ultrasound velocity and attenuation, both on cortical and on trabecular bone. The reader will not only discover the state-of-the-art when reading though this book. This book can give a taste of the fascinating perspectives the research in bone biomechanics still have to offer, even after more than 100 years.


Skeletal Aging and Osteoporosis

Skeletal Aging and Osteoporosis
Author: Matthew J. Silva
Publisher: Springer Science & Business Media
Total Pages: 261
Release: 2012-08-30
Genre: Technology & Engineering
ISBN: 3642180531

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The focus of this book is on mechanical aspects of skeletal fragility related to aging and osteoporosis. Topics include: Age-related changes in trabecular structure and strength; age-related changes in cortical material properties; age-related changes in whole-bone structure; predicting bone strength and fracture risk using image-based methods and finite element analysis; animal models of osteoporosis and aging; age-related changes in skeletal mechano responsiveness; exercise and physical interventions for osteoporosis.


Bone Cell Biomechanics, Mechanobiology and Bone Diseases

Bone Cell Biomechanics, Mechanobiology and Bone Diseases
Author: Airong Qian
Publisher: Elsevier
Total Pages: 422
Release: 2023-08-28
Genre: Reference
ISBN: 0323994849

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Bone Cell Biomechanics, Mechanobiology and Bone Diseases provides a comprehensive overview of recent knowledge and advances of bone cell biomechanics and related bone diseases, highlighting the cellular basis for bone responding to mechanical stimuli. The book not only provides a general overview of bone cell biology, but also the most recent advances of bone cell biomechanics, mechanobiology, the relationship between bone cell biomechanics and bone diseases, as well as the underlying mechanism. This will be useful in understanding the role of mechanobiology in bone health and bone diseases, as well for investigating novel strategies for diagnosis and therapy of bone diseases. Cells covered in the book include osteocyte, BM-MSC, osteoblast, osteoclast and chondrocyte. Cone diseases covered are osteoporosis, scoliosis and osteoarthritis. This comprehensive reference is written for researchers, scientists, clinicians and students. Presents a comprehensive introduction of current knowledge and recent advances of bone cell biomechanics Introduces new technologies for bone cell research Discusses the bone cell mechanotransduction, mechanism and bone diseases


Clinical Biomechanics and Related Research

Clinical Biomechanics and Related Research
Author: Yasusuke Hirasawa
Publisher: Springer Science & Business Media
Total Pages: 422
Release: 2012-12-06
Genre: Medical
ISBN: 4431668594

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Clinical biomechanics is a rapidly changing field with an increasingly wide appeal. While the core subjects of biomechanics remain the behavior of bones, joints, ligaments, and muscles, this book focuses on more clinical aspects such as artificial joints, tissue transplantations, and the effects of disease on biomechanical properties. Also featured are special studies of the hand, spine, vascular system, and the analysis of three-dimensional motion. Based on the 20th Annual Meeting of the Japanese Society for Clinical Biomechanics and Related Research, this book provides an overview of the subject as well as describing many exciting new concepts and innovative methods for analyzing biomechanical systems. It should appeal across a wide spectrum of professions, proving indispensable to everyone from orthopedic surgeons to engineers with an interest in biology.


Bone Remodeling Process

Bone Remodeling Process
Author: Rabeb Ben Kahla
Publisher: Academic Press
Total Pages: 238
Release: 2021-08-14
Genre: Technology & Engineering
ISBN: 0323902057

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Bone Remodeling Process: Mechanics, Biology, and Numerical Modeling provides a literature review. The first part of the book discusses bones in a normal physiological condition, bringing together the involved actors and factors reported over the past two decades, and the second discusses pathological conditions, highlighting the attack vectors of each bone disease. The third part is devoted to the mathematical descriptions of bone remodeling, formulated to develop models able to provide information that is not amenable to direct measurement, while the last part focuses on models using the finite element method in investigating bone biomechanics.This book creates an overall image of the complex communication network established between the diverse remodeling actors, based on overwhelming control evidence revealed over recent years, as well as visualizes the remodeling defects and possible treatments in each case. It also regroups the models allowing readers to analyze and assess bone mechanical and biological properties. This book details the cellular mechanisms allowing the bone to adapt its microarchitecture to the requirements of the human body, which is the main issue in bone biology and presents the evolution of mathematical modeling used in a bone computer simulation. Each chapter covers a core topic in bone biomechanics Provides a multidisciplinary view that effectively links orthopaedics, cellular biology, mechanics, and computer simulation Draws an overall image about bone biology and cell interactions, for identifying cell populations that are crucial for the remodeling process


Trabecular and Cortical Bone

Trabecular and Cortical Bone
Author: Varsha Subramanium
Publisher: Nova Science Publishers
Total Pages: 0
Release: 2013-10
Genre: Bone
ISBN: 9781628087666

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In this book, the authors present topical research in the study of the morphology, biomechanics and clinical implications of trabecular and cortical bone. Topics discussed include trabecular bone biomechanics and morphology; cortical bone as an enduring depot of bone-seeking contaminants and the evaluation of cortical bone resportion rate on the basis of a contaminant (90SR) measurement in humans; evaluation of apparent stress and strain at fracture of human trabecular bone under quasi-static compression load using micro-CT finite elements simulation; application of computational modelling to predict the effect of exercise on whole bone strength; advancements in cortical bone imaging; morphology of the pelvis (acetabulum) and femur; the release kinetics of bone morphogenetic proteins from demineralised cortical bone grafts; and preservation of cortical bone in oral and maxillofacial surgery procedures.


Mechanical Testing of Bone and the Bone-Implant Interface

Mechanical Testing of Bone and the Bone-Implant Interface
Author: Yuehuei H. An
Publisher: CRC Press
Total Pages: 650
Release: 1999-11-29
Genre: Medical
ISBN: 1420073567

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The mechanical properties of whole bones, bone tissue, and the bone-implant interfaces are as important as their morphological and structural aspects. Mechanical Testing of Bone and the Bone-Implant Interface helps you assess these properties by explaining how to do mechanical testing of bone and the bone-implant interface for bone-related research


Multiscale Biomechanics

Multiscale Biomechanics
Author: Jean-Francois Ganghoffer
Publisher: Elsevier
Total Pages: 584
Release: 2018-02-03
Genre: Science
ISBN: 0081021151

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Multiscale Biomechanics provides new insights on multiscale static and dynamic behavior of both soft and hard biological tissues, including bone, the intervertebral disk, biological membranes and tendons. The physiological aspects of bones and biological membranes are introduced, along with micromechanical models used to compute mechanical response. A modern account of continuum mechanics of growth and remodeling, generalized continuum models to capture internal lengths scales, and dedicated homogenization methods are provided to help the reader with the necessary theoretical foundations. Topics discussed include multiscale methods for fibrous media based on discrete homogenization, generalized continua constitutive models for bone, and a presentation of recent theoretical and numerical advances. In addition, a refresher on continuum mechanics and more advanced background related to differential geometry, configurational mechanics, mechanics of growth, thermodynamics of open systems and homogenization methods is given in separate chapters. Numerical aspects are treated in detail, and simulations are presented to illustrate models. This book is intended for graduate students and researchers in biomechanics interested in the latest research developments, as well as those who wish to gain insight into the field of biomechanics. Provides a clear exposition of multiscale methods for fibrous media based on discrete homogenization and the consideration of generalized continua constitutive models for bone Presents recent theoretical and numerical advances for bone remodeling and growth Includes the necessary theoretical background that is exposed in a clear and self-contained manner Covers continuum mechanics and more advanced background related to differential geometry, configurational mechanics, mechanics of growth, thermodynamics of open systems and homogenization methods


Fundamental Biomechanics in Bone Tissue Engineering

Fundamental Biomechanics in Bone Tissue Engineering
Author: Xiaodu Wang
Publisher: Morgan & Claypool Publishers
Total Pages: 216
Release: 2010
Genre: Technology & Engineering
ISBN: 1608451690

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Bone repair presents a unique challenge to tissue engineering strategies because bone defects often occur at sites that withstand significant mechanical loading. Thus, the design and fabrication of bone tissue engineering products often require both sufficient mechanical competence and adequate architecture that promotes osteogenesis. To help reconcile these opposing needs, this book provides basic knowledge on both the biomechanics of bone and the biomechanics of scaffolds currently employed in bone tissue engineering. The intent of this information is to assist tissue engineers not only in design and fabrication of bone tissue engineering products, but also in the evaluation of such products and outcomes.


Bone Mechanics

Bone Mechanics
Author: Stephen C. Cowin
Publisher: CRC Press
Total Pages: 328
Release: 1989
Genre: Medical
ISBN:

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This informative volume summarizes what is known about bone mechanics. It describes the methods used to acquire that knowledge and suggests the nature of future research on this topic. This easy-to-read book keeps mathematical notation simple and minimal and presents data in summary form. Bone Mechanics is concerned with the mechanical behavior and functional stress adaptation of whole bones as structural elements, the mechanical behavior and functional adaptation of bone tissue as material, and the physiological significance of the mechanical properties of bone and the biological response of bone to applied stress. Orthopaedic surgeons, dentists, anatomists, biologists, biomedical engineers and physiologists are among those who will find this volume to be of interest.