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Biopsy Diagnosis of Peripheral Neuropathy E-Book

Biopsy Diagnosis of Peripheral Neuropathy E-Book
Author: Gyl Midroni
Publisher: Elsevier Health Sciences
Total Pages: 400
Release: 2015-01-28
Genre: Health & Fitness
ISBN: 1483292436

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This is a standard reference for residents in neurology and neuropathology, and is also a useful book in the electron microscopy laboratory. It provides a practical approach to interpretation of nerve biopsy, and has outstanding micrographs covering both light and electron microscopy. New disease entities are discussed with advances in the understanding of the pathogenesis of each neuropathy. A complete literature review on the subject of subcutaneous nerve biopsy is accompanied by clinical features, and histogenesis of all human polyneuropathies. * Standard reference for residents in neurology and neuropathology * Book useful in electron microscopy laboratory * Outstanding micrographs covering both light and electron microscopy


Biopsy Diagnosis of Peripheral Neuropathy

Biopsy Diagnosis of Peripheral Neuropathy
Author: Juan M Bilbao
Publisher: Springer
Total Pages: 499
Release: 2014-11-05
Genre: Medical
ISBN: 3319073117

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Peripheral nerve analysis is a challenging task for pathologists, given the advent of new diagnoses and techniques of analysis and the impact of molecular genetics. This book presents a simple, logical method for constructing a differential diagnosis based on pathology and clinical presentation. It also provides advice on the selection of ancillary molecular, immunohistochemical and genetic techniques to establish a definitive diagnosis. Clear, authoritative guidance is offered on diagnosis of the full range of neuropathies with the aid of a wealth of high-quality color photomicrographs and electron micrographs. The pathologist will benefit greatly from the identification of a variety of artifacts and normal structures occasionally encountered in nerve biopsies that need to be distinguished from specific pathologic alterations. This user-friendly, practical text will be an invaluable aid in achieving the most specific diagnosis possible.


Biopsy Diagnosis of Peripheral Neuropathy

Biopsy Diagnosis of Peripheral Neuropathy
Author: Gyl Midroni
Publisher: Butterworth-Heinemann
Total Pages: 504
Release: 1995
Genre: Health & Fitness
ISBN:

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A highly illustrated (bandw) monograph directed to neurologists and pathologists, combining a practical approach to nerve biopsy interpretation in peripheral neuropathy with an overview of the progress of the past two decades in the understanding of peripheral nerve pathobiology. Also covered are clinical features of polyneuropathy and the microscopic anatomy of nerves. Emphasis is placed on the usefulness and limitations of nerve biopsy as a diagnostic tool. The material examined consists of some 700 nerve biopsies collected over a 22-year period at St. Michael's Hospital in Toronto. Annotation copyright by Book News, Inc., Portland, OR


Color Atlas of Nerve Biopsy Pathology

Color Atlas of Nerve Biopsy Pathology
Author: Shin J. Oh
Publisher: CRC Press
Total Pages: 233
Release: 2001-08-29
Genre: Medical
ISBN: 1420039806

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As a professional working in the frontlines of tissue diagnosis and in everyday practice, you need a reference that gives you practical information in an easy-to-use format. Containing over 300 photographs, micrographs, and line drawings, including over 60 color illustrations, Color Atlas of Nerve Biopsy Pathology supplies a clear picture of common


Peripheral Nerve Disorders

Peripheral Nerve Disorders
Author: Rosalind King
Publisher: Elsevier Inc. Chapters
Total Pages: 41
Release: 2013-08-17
Genre: Medical
ISBN: 0128078405

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This chapter discusses the indications for biopsying a peripheral nerve and the factors involved in justifying this decision and then deciding which nerve to take. There is a table summarizing some of the causes of neuropathy and attempting to relate these to the probability that nerve biopsy would be helpful in diagnosis. The surgical procedure for the nerve biopsy is described including aftercare and possible complications. The techniques involved in processing and staining the nerve are discussed. This section includes the possibilities of creating artefactual damage by mishandling or poor technique, and how to avoid these. Modification to the standard resin processing schedule to allow the teasing out of individual nerve fibers is briefly described, as are methods for measuring fiber density, fiber size and myelin thickness. There is also a brief discussion of the applications of immunohistochemistry. This is followed by a section on interpretation by light and electron microscopy in which some of the more important diagnostic features are described and illustrated, as are nonspecific morphological findings. Interpretation of teased fiber preparations is discussed. Finally, some common causes of incorrect interpretation are mentioned.


Companion to Peripheral Neuropathy

Companion to Peripheral Neuropathy
Author: Peter James Dyck
Publisher: Elsevier Health Sciences
Total Pages: 385
Release: 2010
Genre: Medical
ISBN: 1437700012

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"An excellent companion volume to Dyck and Thomas' authoritative and comprehensive Peripheral Neuropathy, this visually rich resource features illustrated case studies that explore the evaluation and management of the most common peripheral nerve disorders. Leading authorities in the field contribute clues to the diagnosis, clinical features, imaging studies, histopathology, and more for each, case. You'll benefit from new perspectives on the causes of peripheral nerve disorders, helping you to diagnose and treat every condition you're likely to encounter." --Book Jacket.


Diagnosis and Management of Peripheral Nerve Disorders

Diagnosis and Management of Peripheral Nerve Disorders
Author: Jerry R. Mendell
Publisher: Oxford University Press
Total Pages: 718
Release: 2001-03-08
Genre: Medical
ISBN: 0195133013

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Peripheral neuropathies represent a challenging subject for most physicians. This is an up-to-date, comprehensive, and readable book on peripheral neuropathies that includes concise information on the clinical, electrophysiological, pathological, pathogenic, and treatment aspects of the most important disorders. New molecular and serologic diagnostic tests are discussed. Sections are devoted to nerve and skin biopsy techniques and findings, quantitative sensory and autonomic reflex tests. Case examples are used liberally throughout the text. The editors: Mendell, Kissel, and Cornblath are experienced clinicians that bring complementary knowledge to each of the subjects. Additional authors have been handpicked for specific topics which add to the value of the edition.


Textbook of Peripheral Neuropathy

Textbook of Peripheral Neuropathy
Author: Peter D. Donofrio, MD
Publisher: Demos Medical Publishing
Total Pages: 469
Release: 2012-04-17
Genre: Medical
ISBN: 1617050342

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Textbook of Peripheral Neuropathy is a practical but authoritative reference for clinicians in anymedical specialty who are evaluating and treating patients with signs and symptoms of a peripheralneuropathy. Reviewing the full spectrum of clinically significant neuropathies, the book contains chapterson common and rare forms including mononeuropathy in the upper and lower extremities, mononeuritismultiplex, diffuse and symmetric polyneuropathies, brachial and lumbrosacral plexopathies, and spinalroot disordersódisorders that can mimic diffuse and/or focal neuropathies, complicating diagnosis andevaluation. Coverage encompasses both inherited and acquired diseases, including neuropathies arisingfrom physical injury, diabetes, alcoholism, toxins, autoimmune responses, nutritional deficiencies, vascularand metabolic disorders, medication-induced neuropathies, and idiopathic conditions. The textbookprovides an evidence-based approach to testing, differential diagnosis, and treatment, and should serveas a trusted resource for healthcare professionals confronting the many manifestations of peripheralneuropathy in clinical practice. The chapters are written by internationally renowned expert contributors with deep clinical experienceand contain numerous tables, figures, and algorithms providing clear diagnostic and managementguidelines. Boxed Clinical Pearls and Key Points allow for quick access to pertinent information, making evaluation and review easy and rewarding. Features of Textbook of Peripheral Neuropathy Include: ̈ Practical yet comprehensiveóan accessible ìgo-toî reference for clinicians ̈ Covers all clinically relevant peripheral neuropathies ̈ Clinical Pearls and Key Points are set off from the text for quick reference ̈ Contains clear diagnostic and management guidelines from expert contributors ̈ Structured chapters make it easy to find essential point-of-careinformation


Peripheral Neuropathy & Neuropathic Pain

Peripheral Neuropathy & Neuropathic Pain
Author: Professor Gérard Said
Publisher: tfm Publishing Limited
Total Pages: 219
Release: 2014-09-01
Genre: Medical
ISBN: 1910079022

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Written by one of the world's leading experts — Professor Gérard Said MD FRCP, Dpt de Neurologie, Hôpital de la Salpêtrière, Paris, France Peripheral neuropathy is a common medical condition, the diagnosis of which is often protracted or delayed. It is not always easy to relate a neuropathy to a specific cause. Many people do not receive a full diagnosis, their neuropathy often being described as 'idiopathic' or 'cryptogenic'. It is said that in Europe, one of the most common causes is diabetes mellitus but there are also many other known potential causes. The difficulty of diagnosis, the limited number of treatment options, a perceived lack of knowledge of the subject —except in specialised clinics, the number of which are limited — all add to the difficulties which many neuropathy patients have to face. Another additional problem for many patients is that once having received a full, or even a partial diagnosis, they are then often discharged back to their primary healthcare team who, in many instances, know little about this condition and how it may impact upon their patients' lives. In order to help bridge this gap in medical knowledge and to give healthcare providers a better understanding of this often distressing condition, The Neuropathy Trust has commissioned a new book on this complex topic. Written by one of the world's leading experts on neuropathy, Professor Gérard Said, it is a 'must read' and also a handy reference book for doctors, nurses, physiotherapists, chiropodists/podiatrists and other health professionals.As well as covering the anatomy of the nervous system and the basic pathological processes that may affect the peripheral nerves, the book covers a whole range of neuropathic conditions. These include, for example, Guillain-Barré syndrome, chronic inflammatory demyelinating polyneuropathy, vasculitic neuropathies, infectious neuropathies, diabetic and other metabolic neuropathies, hereditary neuropathies and neuropathies in patients with cancer. Given the almost explosive increase in diabetes predicted over the coming years and the high incidence of HIV infections alone, not to mention all the other possible causes of peripheral neuropathy, no self-respecting medical unit should be without a copy of this new book on their shelves. The author, Professor Gérard Said, is based in the Department of Neurology at the prestigious Hôpital de la Salpêtrière in Paris. He has devoted a lifetime to the study of peripheral neuropathy and — alongside other great neurological names — added much to the world's ever-growing store of knowledge on this complex but fascinating condition which affects so many individuals.


Small Fiber Neuropathy and Related Syndromes: Pain and Neurodegeneration

Small Fiber Neuropathy and Related Syndromes: Pain and Neurodegeneration
Author: Sung-Tsang Hsieh
Publisher: Springer
Total Pages: 184
Release: 2019-04-08
Genre: Medical
ISBN: 981133546X

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This book provides comprehensive coverage of small fiber neuropathy (SFN), from diagnosis to therapy. It focuses on nerve degeneration and neuropathic pain, and their underlying pathology, physiology, psychophysics, genetics and imaging. In particular, this book describes and discusses the major advances in diagnostic techniques for assessing SFN. These include skin biopsy, evoked potentials, quantitative sensory testing and functional studies, as biomarkers of SFN. SFN is a common peripheral nerve disorder, but was often overlooked due to a lack of objective and specific diagnostic tests for the assessment of small nerve fibers. These fibers mediate thermal sensation, pain detection (nociception), and autonomic regulation. Major symptoms of SFN include neuropathic pain, impaired sensation and autonomic dysfunction. Neuropathic pain poses a diagnostic challenge to clinicians, an essential step for selecting appropriate treatment to relieve suffering. SFN frequently develops in systemic diseases such as diabetes mellitus, following chemotherapy, infections etc., or presents as a major feature of various genetic neuropathies (e.g. channelopathy and familial amyloidosis). In addition to describing these conditions which lead to SFN, this book also describes related syndromes of neurodegeneration and pain, including fibromyalgia, visceral pain and hypersensitivity. This definitive book covers both clinical aspects and research progress, which provides in-depth and up-to-date information on SFN. It would be immensely useful for clinicians, neurologists, neuroscientists, diabetologists, and pain specialists. Dr. Sung-Tsang Hsieh is a professor at Department of Neurology and Institute of Anatomy and Cell Biology, College of Medicine, National Taiwan University, Taiwan. He is also the associate dean of College of Medicine, National Taiwan University, Taiwan. Dr. Praveen Anand is a professor at Department of Clinical Neurology and head of Centre for Clinical Translation, Hammersmith Hospital, UK. Dr. Christopher Gibbons is an associate professor of Neurology, Harvard Medical School, Beth Israel Deaconess Medical Center, USA. Dr. Claudia Sommer is a professor of Neurology at the Department of Neurology, Würzburg University Hospital, Germany.