Bioorganic Chemistry Of Signal Transduction PDF Download
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Author | : Herbert Waldmann |
Publisher | : Springer |
Total Pages | : 235 |
Release | : 2003-07-01 |
Genre | : Science |
ISBN | : 3540450351 |
Download Bioorganic Chemistry of Biological Signal Transduction Book in PDF, ePub and Kindle
The transduction of signals from the extracellular space across the plasma membrane into the interior of cells and ultimately to the nucleus, where in - sponse to such external signals the transcription of the genetic code is inf- enced, belongs to the most fundamental and important events in the regulation of the life cycle of cells. During recent years several signal transduction cascades have been elucidated which regulate, for instance, the growth and the prolife- tion of organisms as diverse as mammals, flies, worms and yeast. The general picture which emerged from these investigations is that nature employs a c- bination of non-covalent ligand/protein and protein/protein interactions together with a set of covalent protein modifications to generate the signals and transduce them to their destinations. The ligands which are recognized may be low molecular weight compounds like lipids, inositol derivatives, steroids or microbial products like cyclosporin. They may be proteins like, for instance, growth factors or intracellular adaptor proteins which carry SH2 or SH3 domains, and they may be specific DNA stretches which are selectively rec- nized by transcription factors. These and other aspects of biological signal transduction provide an open and rewarding field for investigations by scientists from various different dis- plines of biology, medical research and chemistry working in academic research institutions or in industry.
Author | : Herbert Waldmann |
Publisher | : Springer |
Total Pages | : 230 |
Release | : 2003-07-01 |
Genre | : Science |
ISBN | : 9783540450351 |
Download Bioorganic Chemistry of Biological Signal Transduction Book in PDF, ePub and Kindle
Author | : |
Publisher | : |
Total Pages | : 215 |
Release | : 1997 |
Genre | : Cellular signal transduction |
ISBN | : |
Download Bioorganic Chemistry of Signal Transduction Book in PDF, ePub and Kindle
Author | : Herbert Waldmann |
Publisher | : |
Total Pages | : 215 |
Release | : 1997 |
Genre | : Cellular signal transduction |
ISBN | : |
Download Bioorganic Chemistry of Signal Transduction Book in PDF, ePub and Kindle
Author | : Gerhard Krauss |
Publisher | : John Wiley & Sons |
Total Pages | : 1024 |
Release | : 2014-02-14 |
Genre | : Science |
ISBN | : 3527667490 |
Download Biochemistry of Signal Transduction and Regulation Book in PDF, ePub and Kindle
Originally based on a graduate course taught by the author, this true classic has once again been extensively updated to incorporate key new findings in biological signaling. With over half of the content re-written, plus 70 brand new and 50 revised figures, this is the most up-to-date textbook on signaling available anywhere. Thanks to its clear structure, hundreds of illustrative drawings, as well as chapter introductions and newly added study questions, this text excels as a companion for a course on biological signaling, and equally as an introductory reference to the field for students and researchers. Generations of students and junior researchers have relied on "the Krauss" to find their way through the bewildering complexity of biological signaling pathways.
Author | : Jonathan W. Boyd |
Publisher | : John Wiley & Sons |
Total Pages | : 336 |
Release | : 2019-04-16 |
Genre | : Science |
ISBN | : 1119060265 |
Download Cellular Signal Transduction in Toxicology and Pharmacology Book in PDF, ePub and Kindle
Covering a key topic due to growing research into the role of signaling mechanisms in toxicology, this book focuses on practical approaches for informatics, big data, and complex data sets. Combines fundamentals / basics with experimental applications that can help those involved in preclinical drug studies and translational research Includes detailed presentations of study methodology and data collection, analysis, and interpretation Discusses tools like experimental design, sample handling, analytical measurement techniques
Author | : ljsbrand M. Kramer |
Publisher | : Academic Press |
Total Pages | : 1126 |
Release | : 2015-10-23 |
Genre | : Science |
ISBN | : 0123948193 |
Download Signal Transduction Book in PDF, ePub and Kindle
A reference on cellular signaling processes, the third edition of Signal Transduction continues in the tradition of previous editions, in providing a historical overview of how the concept of stimulus-response coupling arose in the early twentieth century and shaped our current understanding of the action of hormones, cytokines, neurotransmitters, growth factors and adhesion molecules. In a new chapter, an introduction to signal transduction, the book provides a concise overview of receptor mechanisms, from receptor – ligand interactions to post-translational modifications operational in the process of bringing about cellular changes. The phosphorylation process, from bacteria to men, is discussed in detail. Signal transduction third edition further elaborates on diverse signaling cascades within particular contexts such as muscle contraction, innate and adaptive immunity, glucose metabolism, regulation of appetite, oncogenic transformation and cell fate decision during development or in stem cell niches. The subjects have been enriched with descriptions of the relevant anatomical, histological, physiological or pathological condition. In-depth insight into a subject central to cell biology and fundamental to biomedicine, including the search for novel therapeutic interventions Essential signaling events embedded in rich physiological and pathological contexts Extensive conceptual colour artwork to assist with comprehension of key topics Special emphasis on how molecular structure determines protein function and subcellular localization Employment of unambiguous protein names (symbols) in agreement with leading protein- and gene databases, allowing the learner to extend his/her exploration on the web
Author | : Elliott M. Ross |
Publisher | : Springer Science & Business Media |
Total Pages | : 534 |
Release | : 2013-06-29 |
Genre | : Science |
ISBN | : 3642751369 |
Download Biological Signal Transduction Book in PDF, ePub and Kindle
Proceedings of the NATO Advanced Research Institute on Biological Signal Transduction held on the Island of Spetsai (Greece), August 6 - 17, 1990
Author | : Edward A. Dennis |
Publisher | : Academic Press |
Total Pages | : 603 |
Release | : 2011-04-04 |
Genre | : Science |
ISBN | : 0123838630 |
Download Transduction Mechanisms in Cellular Signaling Book in PDF, ePub and Kindle
Cytosol, the liquid found inside cells, is the site for multiple cell processes, including signaling from the cell membrane to sites within the cell. Cytosolic signaling mechanisms are researched and studied in graduate programs in cell biology, molecular biology, biochemistry, pharmacology, molecular and cellular physiology, pharmacy, and biomedical sciences. Articles written and edited by experts in the field Thematic volume covering material needed for young professionals joining the field of research and graduate students taking survey courses Up-to-date research on signaling systems and mutations in transcription factors that provide new targets for treating disease
Author | : Carl-Henrik Heldin |
Publisher | : Garland Science |
Total Pages | : 404 |
Release | : 1996 |
Genre | : Cell physiology |
ISBN | : 9780748740741 |
Download Signal Transduction Book in PDF, ePub and Kindle
Signal Transduction was published in association with The International Union of Biochemistry and Molecular Biology. In a series of twenty-three short chapters, leading researchers provide cutting-edge reviews of signal transduction, and form cell membrane receptors through to gene regulation. Written for those with a basic understanding of molecular and cell biology, the book will be of particular interest to graduate students and researchers who need to grasp the principles of signal transduction.