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Modeling in Computational Biology and Biomedicine

Modeling in Computational Biology and Biomedicine
Author: Frédéric Cazals
Publisher: Springer Science & Business Media
Total Pages: 333
Release: 2012-11-06
Genre: Mathematics
ISBN: 364231208X

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Computational biology, mathematical biology, biology and biomedicine are currently undergoing spectacular progresses due to a synergy between technological advances and inputs from physics, chemistry, mathematics, statistics and computer science. The goal of this book is to evidence this synergy by describing selected developments in the following fields: bioinformatics, biomedicine and neuroscience. This work is unique in two respects - first, by the variety and scales of systems studied and second, by its presentation: Each chapter provides the biological or medical context, follows up with mathematical or algorithmic developments triggered by a specific problem and concludes with one or two success stories, namely new insights gained thanks to these methodological developments. It also highlights some unsolved and outstanding theoretical questions, with a potentially high impact on these disciplines. Two communities will be particularly interested in this book. The first one is the vast community of applied mathematicians and computer scientists, whose interests should be captured by the added value generated by the application of advanced concepts and algorithms to challenging biological or medical problems. The second is the equally vast community of biologists. Whether scientists or engineers, they will find in this book a clear and self-contained account of concepts and techniques from mathematics and computer science, together with success stories on their favorite systems. The variety of systems described represents a panoply of complementary conceptual tools. On a practical level, the resources listed at the end of each chapter (databases, software) offer invaluable support for getting started on a specific topic in the fields of biomedicine, bioinformatics and neuroscience.


Encyclopedia of Bioinformatics and Computational Biology

Encyclopedia of Bioinformatics and Computational Biology
Author:
Publisher: Elsevier
Total Pages: 3421
Release: 2018-08-21
Genre: Medical
ISBN: 0128114320

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Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics, Three Volume Set combines elements of computer science, information technology, mathematics, statistics and biotechnology, providing the methodology and in silico solutions to mine biological data and processes. The book covers Theory, Topics and Applications, with a special focus on Integrative –omics and Systems Biology. The theoretical, methodological underpinnings of BCB, including phylogeny are covered, as are more current areas of focus, such as translational bioinformatics, cheminformatics, and environmental informatics. Finally, Applications provide guidance for commonly asked questions. This major reference work spans basic and cutting-edge methodologies authored by leaders in the field, providing an invaluable resource for students, scientists, professionals in research institutes, and a broad swath of researchers in biotechnology and the biomedical and pharmaceutical industries. Brings together information from computer science, information technology, mathematics, statistics and biotechnology Written and reviewed by leading experts in the field, providing a unique and authoritative resource Focuses on the main theoretical and methodological concepts before expanding on specific topics and applications Includes interactive images, multimedia tools and crosslinking to further resources and databases


Bioinformatics and Biomedical Engineering

Bioinformatics and Biomedical Engineering
Author: Ignacio Rojas
Publisher: Springer
Total Pages: 571
Release: 2018-04-19
Genre: Computers
ISBN: 3319787233

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This two-volume set LNBI 10813 and LNBI 10814 constitutes the proceedings of the 6th International Work-Conference on Bioinformatics and Biomedical Engineering, IWBBIO 2018, held in Granada, Spain, in April 2018.The 88 regular papers presented were carefully reviewed and selected from 273 submissions. The scope of the conference spans the following areas: bioinformatics for healthcare and diseases; bioinformatics tools to integrate omics dataset and address biological question; challenges and advances in measurement and self-parametrization of complex biological systems; computational genomics; computational proteomics; computational systems for modelling biological processes; drug delivery system design aided by mathematical modelling and experiments; generation, management and biological insights from big data; high-throughput bioinformatic tools for medical genomics; next generation sequencing and sequence analysis; interpretable models in biomedicine and bioinformatics; little-big data. Reducing the complexity and facing uncertainty of highly underdetermined phenotype prediction problems; biomedical engineering; biomedical image analysis; biomedical signal analysis; challenges in smart and wearable sensor design for mobile health; and healthcare and diseases.


Computational Bioengineering and Bioinformatics

Computational Bioengineering and Bioinformatics
Author: Nenad Filipovic
Publisher: Springer
Total Pages: 169
Release: 2021-03-12
Genre: Technology & Engineering
ISBN: 9783030436605

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This book explores the latest and most relevant topics in the field of computational bioengineering and bioinformatics, with a particular focus on patient-specific, disease-progression modeling. It covers computational methods for cardiovascular disease prediction, with an emphasis on biomechanics, biomedical decision support systems, data mining, personalized diagnostics, bio-signal processing, protein structure prediction, biomedical image processing, analysis and visualization, and high-performance computing. It also discusses state-of-the-art tools for disease characterization, and recent advances in areas such as biomechanics, cardiovascular engineering, patient-specific modeling, population-based modeling, multiscale modeling, image processing, data mining, biomedical decision-support systems, signal processing, biomaterials and dental biomechanics, tissue and cell engineering, computational chemistry and high-performance computing. As such, it is a valuable resource for researchers, medical and bioengineering students, and medical device and software experts


Computational Biology and Bioinformatics

Computational Biology and Bioinformatics
Author: Ka-Chun Wong
Publisher: CRC Press
Total Pages: 425
Release: 2016-04-27
Genre: Science
ISBN: 1498725007

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The advances in biotechnology such as the next generation sequencing technologies are occurring at breathtaking speed. Advances and breakthroughs give competitive advantages to those who are prepared. However, the driving force behind the positive competition is not only limited to the technological advancement, but also to the companion data analytical skills and computational methods which are collectively called computational biology and bioinformatics. Without them, the biotechnology-output data by itself is raw and perhaps meaningless. To raise such awareness, we have collected the state-of-the-art research works in computational biology and bioinformatics with a thematic focus on gene regulation in this book. This book is designed to be self-contained and comprehensive, targeting senior undergraduates and junior graduate students in the related disciplines such as bioinformatics, computational biology, biostatistics, genome science, computer science, applied data mining, applied machine learning, life science, biomedical science, and genetics. In addition, we believe that this book will serve as a useful reference for both bioinformaticians and computational biologists in the post-genomic era.


Computational Bioengineering

Computational Bioengineering
Author: Guigen Zhang
Publisher: CRC Press
Total Pages: 508
Release: 2015-04-01
Genre: Medical
ISBN: 1466517565

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Arguably the first book of its kind, Computational Bioengineering explores the power of multidisciplinary computer modeling in bioengineering. Written by experts, the book examines the interplay of multiple governing principles underlying common biomedical devices and problems, bolstered by case studies. It shows you how to take advantage of the la


Mining the Biomedical Literature

Mining the Biomedical Literature
Author: Hagit Shatkay
Publisher: MIT Press
Total Pages: 151
Release: 2012
Genre: Computers
ISBN: 0262017695

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The authors offer an accessible introduction to key ideas in biomedical text mining. The chapters cover such topics as the sources of biomedical text; text-analysis methods in natural language processing; the tasks of information extraction, information retrieval, and text categorization; and methods for empirically assessing textmining systems.


Biomedical and Computational Biology

Biomedical and Computational Biology
Author: Shiping Wen
Publisher: Springer Nature
Total Pages: 624
Release: 2023-02-01
Genre: Science
ISBN: 3031251911

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This book constitutes the revised selected proceedings of Second International Symposium on Biomedical and Computational Biology, BECB 2022, held as a virtual event in August 2022. The 58 full papers included in this book were carefully reviewed and selected from 135 submissions. The papers are organized in topical sections as follows: The Charge Transfer Network Model for Arbitrary Proteins Complexes; A Self-Supervised 3D/2D Registration Method for Incomplete DSA Vessels; The Potential Role of RNA "Writer" TRMT61B in the Immune Regulation of Breast Cancer; Extraction, Composition Analysis and Blood Lipid Lowering Activity of Rana chensinensis Ovum Oil.


Computational Modeling of Biological Systems

Computational Modeling of Biological Systems
Author: Nikolay V Dokholyan
Publisher: Springer Science & Business Media
Total Pages: 360
Release: 2012-02-12
Genre: Science
ISBN: 1461421454

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Computational modeling is emerging as a powerful new approach to study and manipulate biological systems. Multiple methods have been developed to model, visualize, and rationally alter systems at various length scales, starting from molecular modeling and design at atomic resolution to cellular pathways modeling and analysis. Higher time and length scale processes, such as molecular evolution, have also greatly benefited from new breeds of computational approaches. This book provides an overview of the established computational methods used for modeling biologically and medically relevant systems.


Computational Systems Bioinformatics - Methods And Biomedical Applications

Computational Systems Bioinformatics - Methods And Biomedical Applications
Author: Wong Stephen Tin Chi
Publisher: World Scientific Publishing Company
Total Pages: 400
Release: 2008-01-02
Genre: Science
ISBN: 9813106999

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Computational systems biology is a new and rapidly developing field of research, concerned with understanding the structure and processes of biological systems at the molecular, cellular, tissue, and organ levels through computational modeling as well as novel information theoretic data and image analysis methods. By focusing on either information processing of biological data or on modeling physical and chemical processes of biosystems, and in combination with the recent breakthrough in deciphering the human genome, computational systems biology is guaranteed to play a central role in disease prediction and preventive medicine, gene technology and pharmaceuticals, and other biotechnology fields.This book begins by introducing the basic mathematical, statistical, and data mining principles of computational systems biology, and then presents bioinformatics technology in microarray and sequence analysis step-by-step. Offering an insightful look into the effectiveness of the systems approach in computational biology, it focuses on recurrent themes in bioinformatics, biomedical applications, and future directions for research.