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Biomechanics of the Gastrointestinal Tract

Biomechanics of the Gastrointestinal Tract
Author: Hans Gregersen
Publisher: Springer Science & Business Media
Total Pages: 294
Release: 2013-04-18
Genre: Medical
ISBN: 1447137426

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Biomechanics of the Gastrointestinal Tract is an up-to-date book for researchers on the study of the mechanical properties and the motor system of the gastrointestinal tract. A well-illustrated book, it provides a comprehensive overview to relevant tissue geometry, morphology and biomechanical theory. Separate chapters cover smooth muscle and nerve function including the application to animal and human studies of motility, symptoms and pain, determination of the true resting state, history-dependent properties, and tissue remodelling in disease. Several methods and diagnostic applications such as determination of in vivo length-tension diagrams and multimodal pain testing are completely new but will undoubtedly be used by many in the future. New non-invasive imaging techniques based on ultrasound, MR- and CT-scanning in combination with balloon distension are emerging as the techniques for future in vivo studies.


Mathematical Foundations and Biomechanics of the Digestive System

Mathematical Foundations and Biomechanics of the Digestive System
Author: Roustem N. Miftahof
Publisher: Cambridge University Press
Total Pages: 241
Release: 2010-05-06
Genre: Technology & Engineering
ISBN: 1139485776

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Mathematical modelling of physiological systems promises to advance our understanding of complex biological phenomena and pathophysiology of diseases. In this book, the authors adopt a mathematical approach to characterize and explain the functioning of the gastrointestinal system. Using the mathematical foundations of thin shell theory, the authors patiently and comprehensively guide the reader through the fundamental theoretical concepts, via step-by-step derivations and mathematical exercises, from basic theory to complex physiological models. Applications to nonlinear problems related to the biomechanics of abdominal viscera and the theoretical limitations are discussed. Special attention is given to questions of complex geometry of organs, effects of boundary conditions on pellet propulsion, as well as to clinical conditions, e.g. functional dyspepsia, intestinal dysrhythmias and the effect of drugs to treat motility disorders. With end of chapter problems, this book is ideal for bioengineers and applied mathematicians.


New Advances in Gastrointestinal Motility Research

New Advances in Gastrointestinal Motility Research
Author: L. K. Cheng
Publisher: Springer Science & Business Media
Total Pages: 266
Release: 2013-06-01
Genre: Medical
ISBN: 9400765614

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Research into gastrointestinal motility has received renewed interest in part due to recent advances in the techniques for measuring the structure and function of gastrointestinal cells, tissue and organs. The integration of this wealth of data into biophysically based computation models can aid in interpretation of experimental and clinical measurements and the refinement of measurement techniques. The contents of this book span multiple scales - from cell, tissue, organ, to whole body and is divided into four broad sections covering: i) gastrointestinal cellular activity and tissue structure; (ii) techniques for measuring, analyzing and visualizing high-resolution extra-cellular recordings; (iii) methods for sensing gastroelectrical activity using non-invasive bio-electro-magnetic fields and for modulating the underlying gastric electrical activity and finally (iv) methods for assessing manometric and videographic motility patterns and the application of these data for predicting the flow and mixing behavior of luminal contents by using computational fluid dynamic techniques. This book aims to provide both an overview of historical and existing research techniques as well as to highlight future directions and challenges for the community as a whole. It will be suitable for clinicians to understand the cellular and biophysical underpinnings of gastric emptying, gastroenterologists, surgeons, bioengineers and all scientists with interests in gastrointestinal motility research.


Clinical Mechanics in the Gut: An Introduction

Clinical Mechanics in the Gut: An Introduction
Author: Hans Gregersen
Publisher: Bentham Science Publishers
Total Pages: 252
Release: 2016-01-25
Genre: Medical
ISBN: 1681081180

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The gastrointestinal tract is a series of organs each with distinct mechanical functions. Each organ within the system brings food contents in the gut lumen to the site of absorption through separate mechanical functions. These mechanical functions are generated by a fine-tuned interaction between neuronal networks and active muscle layers. The passive components of the gastrointestinal wall such as the collagen-rich submucosa also play an important role in these mechanical actions. Clinical Mechanics in The Gut provides a thorough understanding of the anatomy and biomechanics of the physiological function and pathophysiology of the gastrointestinal tract. The book first gives an introduction to readers about the physical geometry of the gastrointestinal tract followed by a detailed explanation of biomechanical theory and its application to approximating and modeling gut mechanics. This is expanded further by detailed explanations of gut muscle and motor nerve functions in proceeding chapters. A biomechanical evaluation of disorders of regulatory mechanisms such as achalasia and Hirschsprung disease and disorders of effector mechanisms such as reflux disease, systemic sclerosis of the gastrointestinal tract and colonic diverticular disease are also included. Readers will, therefore, gain an understanding about clinical problems in gastroenterology from a bioengineering and modeling perspective. Clinical Mechanics in The Gut is a useful reference for gastroenterology researchers, biomedical engineers and systems biologists seeking to understand the physiology of the gut and applying this knowledge to surgical procedures, computer-based modeling systems and robotics.


Basic and New Aspects of Gastrointestinal Ultrasonography

Basic and New Aspects of Gastrointestinal Ultrasonography
Author: Svein ?degaard
Publisher: World Scientific
Total Pages: 519
Release: 2005
Genre: Medical
ISBN: 9812388451

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- Covers both basic and advanced ultrasonography as well as state-of-the-art research topics in gastroenterology - Has a wide range of authors with expertise in medicine, physiology, GI motility, engineering, computer graphics, imaging, and ultrasound technology - Highlights very original methods of GI ultrasound scanning using many different ultrasound modalities - Uses a unique, combined approach of ultrasonography and biomechanics to GI physiology and pathophysiology - Contains a variety of ultrasound images and illustrations, in color


Biomechanics

Biomechanics
Author: Jerrod H. Levy
Publisher: Nova Science Publishers
Total Pages: 0
Release: 2010
Genre: Biomechanics
ISBN: 9781607413943

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Biomechanics is the application of mechanical principles (statics, strength of materials and stress analysis to the solution of biological problems of living organisms. This includes bioengineering, the research and analysis of the mechanics of living organisms and the application of engineering principles to and from biological systems. This research and analysis can be carried forth on multiple levels, from the molecular, wherein biomaterials such as collagen and elastin are considered, all the way up to the tissue and organ level. This new and important book gathers the latest research from around the globe in the study of this dynamic field with a focus on issues such as; art biomechanics, understanding corneal biomechanics, biomechanical remodelling of the diabetic gastrointestinal tract, biomechanics in children with cerebral palsy, cell biomechanics for orthopaedic implants, and others.


Biomechanics of the Small Intestinal Contractions

Biomechanics of the Small Intestinal Contractions
Author: Ravi Kant Avvari
Publisher:
Total Pages: 0
Release: 2019
Genre: Electronic books
ISBN:

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The small intestine is a part of the gastrointestinal segment comprising of the duodenum, jejunum, and ileum. They help to process the gastric contents for further digestion, which involves mixing with duodeno-biliary-pancreatic (DBP) secretions to facilitate the chemical digestion, and homogenization of the luminal contents through contractions of the circular and longitudinal smooth muscle fibers of the intestine. The contractions of these smooth muscle fibers develops the mechanical forces at the mucosal wall, which as a consequence, transfers its momentum to the underlying fluid to develop the fluid flows, suggesting relevance of mechanics in physiology. The resulting flows are what drive the digestion. Changes in contractility of wave shapes of circular and longitudinal smooth muscle contractions and fluid rheology are known to affect the digestive process through generation of various flow patterns that differ in luminal pressure, peak velocity, extent of shearing/ mixing, volume of mixing, and flow rate. Recent studies indicate that the digestive process can be very specific such as to cause lipid digestion through segmental contractions and transport by eliciting propagating contractions, suggesting that the intestine manages to digest a variety of food in an efficient manner by eliciting appropriate contractions.


Integrated Nano-Biomechanics

Integrated Nano-Biomechanics
Author: Takami Yamaguchi
Publisher: William Andrew
Total Pages: 314
Release: 2018-06-27
Genre: Medical
ISBN: 0323389597

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Integrated Nano-Biomechanics provides an integrated look into the rapidly evolving field of nanobiomechanics. The book demystifies the processes in living organisms at the micro- and nano-scale through mechanics, using theoretical, computational and experimental means. The book develops the concept of integrating different technologies along the hierarchical structure of biological systems and clarifies biomechanical interactions among different levels for the analysis of multi-scale pathophysiological phenomena. With a focus on nano-scale processes and biomedical applications, it is shown how knowledge obtained can be utilized in a range of areas, including diagnosis and treatment of various human diseases and alternative energy production. This book is based on collaboration of researchers from a unique combination of fields, including biomechanics, computational mechanics, GPU application, electron microscopy, biology of motile micro-organisms, entomological mechanics and clinical medicine. The book will be of great interest to scientists and researchers involved in disciplines, such as micro- and nano-engineering, bionanotechnology, biomedical engineering, micro- and nano-scale fluid-mechanics (such as in MEMS devices), nanomedicine and microbiology, as well as industries such as optical devices, computer simulation, plant based energy sources and clinical diagnosis of the gastric diseases. Provides knowledge of integrated biomechanics, focusing on nano-scale, in this rapidly growing research field Explains how the different technologies can be integrated and applied in a variety of biomedical application fields, as well as for alternative energy sources Uses a collaborative, multidisciplinary approach to provide a comprehensive coverage of nano-biomechanics


The Physical Processes of Digestion

The Physical Processes of Digestion
Author: Roger G. Lentle
Publisher: Springer Science & Business Media
Total Pages: 280
Release: 2011-06-03
Genre: Technology & Engineering
ISBN: 1441994491

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Food research (and funding) is becoming more and more focused on health. While researchers and product developers have made great strides in food engineering, there needs to be increased focus on what happens when the food is actually digested. How is the food absorbed? Do the benefits remain? Digestion is a complex topic, and this will be the first book aimed at food researchers. Authored by a physiologist and a food engineer, the book will be a welcome addition to the literature.


The Impact of Food Bioactives on Health

The Impact of Food Bioactives on Health
Author: Kitty Verhoeckx
Publisher: Springer
Total Pages: 341
Release: 2015-04-29
Genre: Technology & Engineering
ISBN: 3319161040

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“Infogest” (Improving Health Properties of Food by Sharing our Knowledge on the Digestive Process) is an EU COST action/network in the domain of Food and Agriculture that will last for 4 years from April 4, 2011. Infogest aims at building an open international network of institutes undertaking multidisciplinary basic research on food digestion gathering scientists from different origins (food scientists, gut physiologists, nutritionists...). The network gathers 70 partners from academia, corresponding to a total of 29 countries. The three main scientific goals are: Identify the beneficial food components released in the gut during digestion; Support the effect of beneficial food components on human health; Promote harmonization of currently used digestion models Infogest meetings highlighted the need for a publication that would provide researchers with an insight into the advantages and disadvantages associated with the use of respective in vitro and ex vivo assays to evaluate the effects of foods and food bioactives on health. Such assays are particularly important in situations where a large number of foods/bioactives need to be screened rapidly and in a cost effective manner in order to ultimately identify lead foods/bioactives that can be the subject of in vivo assays. The book is an asset to researchers wishing to study the health benefits of their foods and food bioactives of interest and highlights which in vitro/ex vivo assays are of greatest relevance to their goals, what sort of outputs/data can be generated and, as noted above, highlight the strengths and weaknesses of the various assays. It is also an important resource for undergraduate students in the ‘food and health’ arena.