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Biomaterials for Cancer Therapeutics

Biomaterials for Cancer Therapeutics
Author: Kinam Park
Publisher: Woodhead Publishing
Total Pages: 783
Release: 2020-03-05
Genre: Technology & Engineering
ISBN: 0081029845

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Biomaterials for Cancer Therapeutics: Evolution and Innovation, Second Edition, discusses the role and potential of biomaterials in treating this prevalent disease. The first part of the book discusses the fundamentals of biomaterials for cancer therapeutics. Part Two discusses synthetic vaccines, proteins and polymers for cancer therapeutics. Part Three focuses on theranosis and drug delivery systems, while the final set of chapters look at biomaterial therapies and cancer cell interaction. Cancer affects people of all ages, and approximately one in three people are estimated to be diagnosed with cancer during their lifetime. Extensive research is being undertaken by many different institutions to explore potential new therapeutics, and biomaterials technology is being developed to target, treat and prevent cancer. Hence, this book is a welcomed resource to the discussion. Provides a complete overview of the latest research into the potential of biomaterials for the diagnosis, treatment and prevention of cancer Discusses how the properties of specific biomaterials make them important in cancer treatment Covers synthetic vaccines, proteins and polymers for cancer therapeutics


Biomaterials for Cancer Therapeutics

Biomaterials for Cancer Therapeutics
Author: Kinam Park
Publisher: Elsevier
Total Pages: 543
Release: 2013-11-23
Genre: Technology & Engineering
ISBN: 0857096761

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Cancer can affect people of all ages, and approximately one in three people are estimated to be diagnosed with cancer during their lifetime. Extensive research is being undertaken by many different institutions to explore potential new therapeutics, and biomaterials technology is now being developed to target, treat and prevent cancer. This unique book discusses the role and potential of biomaterials in treating this prevalent disease.The first part of the book discusses the fundamentals of biomaterials for cancer therapeutics. Chapters in part two discuss synthetic vaccines, proteins and polymers for cancer therapeutics. Part three focusses on theranosis and drug delivery systems, whilst the final set of chapters look at biomaterial therapies and cancer cell interaction.This extensive book provides a complete overview of the latest research into the potential of biomaterials for the diagnosis, therapy and prevention of cancer. Biomaterials for cancer therapeutics is an essential text for academics, scientists and researchers within the biomedical industry, and will also be of interest to clinicians with a research interest in cancer therapies and biomaterials. A complete overview of the latest research into the potential of biomaterials for the diagnosis, therapy and prevention of cancer Discusses the fundamentals of biomaterials for cancer therapeutics Discusses synthetic vaccines, proteins and polymers for cancer therapeutics


Bio-Nanomedicine for Cancer Therapy

Bio-Nanomedicine for Cancer Therapy
Author: Flavia Fontana
Publisher: Springer Nature
Total Pages: 358
Release: 2021-02-04
Genre: Medical
ISBN: 3030581748

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The book covers the latest developments in biologically-inspired and derived nanomedicine for cancer therapy. The purpose of the book is to illustrate the significance of naturally-mimicking systems for enhancing the dose delivered to the tumor, to improve stability, and prolong the circulation time. Moreover, readers are presented with advanced materials such as adjuvants for immunostimulation in cancer vaccines. The book also provides a comprehensive overview of the current status of academic research. This is an ideal book for students, researchers, and professors working in nanotechnology, cancer, targeted drug delivery, controlled drug release, materials science, and biomaterials as well as companies developing cancer immunotherapy.


Engineering PH-responsive Biomaterials for Cancer Immunotherapy

Engineering PH-responsive Biomaterials for Cancer Immunotherapy
Author: Meilyn Sylvestre
Publisher:
Total Pages: 252
Release: 2021
Genre:
ISBN:

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Recent advances in immunotherapy have transformed cancer treatment, while highlighting the complex interactions between the immune system and tumors. For delivery of unstable molecules or immunogenic agents, these therapies often employ nanoformulations to deliver therapeutics to diseased tissue while minimizing off-target toxicity. However, delivery of these carriers is severely limited by numerous biological barriers, preventing therapies from reaching sufficient therapeutic concentrations. Carrier accumulation can be enhanced by incorporation of passive and active targeting, and/or stimuli-responsive elements to help steer the carrier to the appropriate diseased tissues, cells, and intracellular compartments. In this work, we seek to engineer new therapies to enhance targeting and delivery of cancer therapeutics by combining both active and passive targeting strategies. Part I motivates tumor-associated macrophages as immunotherapy targets (Chapter 1), leading into our first approach in which we identified a novel targeting ligand that binds to human tumor-associated macrophages and monocytes (Chapter 2). Part II discusses the challenges of peptide delivery in oncology applications (Chapter 3), prefacing our designed peptide-polymer conjugates that passively accumulate in tumors and respond to external pH to facilitate intracellular peptide delivery upon cellular internalization. Using this strategy, we designed a polymeric delivery system to safely deliver (Chapter 4) a variety of immunogenic peptides (Chapters 5, 6, and 7). Part III outlines the challenges in delivering therapeutics past the blood-brain barrier (Chapter 8), and reports the progress on the development of targeted nanoparticles for brain cancer treatment (Chapter 9).


Nanobiomaterials in Cancer Therapy

Nanobiomaterials in Cancer Therapy
Author: Alexandru Grumezescu
Publisher: William Andrew
Total Pages: 0
Release: 2016-05-30
Genre: Technology & Engineering
ISBN: 0323428630

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Nanobiomaterials in Cancer Therapy


Nanobiomaterials in Cancer Therapy

Nanobiomaterials in Cancer Therapy
Author: Alexandru Grumezescu
Publisher: William Andrew
Total Pages: 589
Release: 2016-03-22
Genre: Medical
ISBN: 032342886X

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Nanobiomaterials in Cancer Therapy presents the major applications of nanobiomaterials in oncology, offering an up-to-date overview of the latest research in this field. Utilizing nanobiomaterials, novel therapeutic approaches enable significant improvements in drug-loading capacity, formulation stability and drug efficiency. In this book, leading researchers from around the world share their expertise and unique insights. The book covers the fabrication methods of platforms for multimodal and combinatorial therapeutic options, along with simultaneous and real-time cancer imaging, and innovative approaches for oncology by passive or active pathways of multifunctional nanocarriers. The work also classifies and discusses engineered nanobiosystems for cancer therapy, prevention, and low cancer recurrence or relapse. This book will be of interest to postdoctoral researchers, professors and students engaged in the fields of materials science, biotechnology and applied chemistry. It will also be highly valuable to those working in industry, including pharmaceutics and biotechnology companies, medical researchers, biomedical engineers and advanced clinicians. A comprehensive resource for researchers, practitioners and students working in biomedical, biotechnological and engineering fields A valuable guide to recent scientific progress and the latest application methods Discusses novel opportunities and ideas for developing or improving technologies in nanomedicine and nanobiology


Nanoengineering of Biomaterials

Nanoengineering of Biomaterials
Author: Sougata Jana
Publisher: John Wiley & Sons
Total Pages: 1063
Release: 2022-04-18
Genre: Science
ISBN: 3527349049

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A comprehensive discussion of various types of nanoengineered biomaterials and their applications In Nanoengineering of Biomaterials: Drug Delivery & Biomedical Applications, an expert team of chemists delivers a succinct exploration of the synthesis, characterization, in-vitro and in-vivo drug molecule release, pharmacokinetic activity, pharmacodynamic activity, and the biomedical applications of several types of nanoengineered biomaterials. The editors have also included resources to highlight the most current developments in the field. The book is a collection of valuable and accessible reference sources for researchers in materials chemistry and related disciplines. It uses a functions-directed approach to using organic and inorganic source compounds that translate into biological systems as scaffolds, micelles, dendrimers, and other delivery systems. Nanoengineering of Biomaterials offers readers up-to-date chemistry and material science insights that are readily transferrable to biomedical systems. The book also includes: Thorough introductions to alginate nanoparticle delivery of therapeutics and chitosan-based nanomaterials in biological applications Comprehensive explorations of nanostructured carrageenan as a drug carrier, gellan gum nanoparticles in drug delivery, and guar-gum nanoparticles in the delivery of bioactive molecules Practical discussions of protein-based nanoparticles for drug delivery, solid lipid nanoparticles as drug carriers, and pH-responsive nanoparticles in therapy In-depth examinations of stimuli-responsive nano carriers in drug targeting Perfect for pharmaceutical chemists, materials scientists, polymer chemists, life scientists, and medicinal chemists, Nanoengineering of Biomaterials: Drug Delivery and Biomedical Applications is also an indispensable resource for biologists and bioengineers seeking a one-stop reference on the transferability of materials chemistry and nanotechnology to biomedicine.


Biomaterials in Translational Medicine

Biomaterials in Translational Medicine
Author: Lei Yang
Publisher: Academic Press
Total Pages: 358
Release: 2018-11-30
Genre: Technology & Engineering
ISBN: 012813478X

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Biomaterials in Translational Medicine delivers timely and detailed information on the latest advances in biomaterials and their role and impact in translational medicine. Key topics addressed include the properties and functions of these materials and how they might be applied for clinical diagnosis and treatment. Particular emphasis is placed on basic fundamentals, biomaterial formulations, design principles, fabrication techniques and transitioning bench-to-bed clinical applications. The book is an essential reference resource for researchers, clinicians, materials scientists, engineers and anyone involved in the future development of innovative biomaterials that drive advancement in translational medicine. Systematically introduces the fundamental principles, rationales and methodologies of creating or improving biomaterials in the context of translational medicine Includes the translational or commercialization status of these new biomaterials Provides the reader with enough background knowledge for a fundamental grip of the difficulties and technicalities of using biomaterial translational medicine Directs the reader on how to find other up-to-date sources (i.e. peer reviewed journals) in the field of translational medicine and biomaterials


Nanooncology

Nanooncology
Author: Gil Gonçalves
Publisher: Springer
Total Pages: 455
Release: 2018-06-01
Genre: Technology & Engineering
ISBN: 3319898787

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This book presents a systematic overview of the most relevant nanomaterials and their respective intrinsic properties that have been highly explored by the scientific community and pharmaceutical companies in several different modalities for cancer therapy and bioimaging. The chapters explore the synergistic effects provided by the different nanostructured materials and highlight the main in vitro and in vivo therapeutic achievements on cancer. This work also provides relevant discussion about the recent progresses and future challenges that nanotechnology faces on the conception of more efficient nanoformulations against primary tumors, circulating cancer cells and metastases.