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Biomarkers in Periodontal Health and Disease

Biomarkers in Periodontal Health and Disease
Author: Nurcan Buduneli
Publisher: Springer Nature
Total Pages: 90
Release: 2019-12-31
Genre: Medical
ISBN: 3030373177

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This book examines all aspects of the progress being made towards the development of highly specific and sensitive biomarkers that will overcome the shortcomings of clinical assessments in periodontics. The opening chapters present the basic anatomic features of periodontal tissues, outline the nature and pathogenic mechanisms of periodontal diseases, and discuss both conventional and novel methods of diagnosis with reference to their specificity and sensitivity. The potential role of biomarkers in periodontal diagnosis is then presented in the light of the published data. The biological samples in which potential biomarkers are sought are evaluated comparatively, drawing attention to their strengths and weaknesses, and the available technologies for biomarker studies are reviewed. The potential benefits of biomarkers are also discussed with regard to the possible bidirectional interactions between periodontal diseases and systemic health. Finally, the past, present, and future of periodontics are examined from a broader perspective. Readers will find the book to be an ideal summary of the state of the art in the field as biomarkers emerge that promise to facilitate periodontal diagnostics and permit timely, personally tailored interventions.


Periodontal Disease

Periodontal Disease
Author:
Publisher: BoD – Books on Demand
Total Pages: 100
Release: 2020-02-05
Genre: Medical
ISBN: 1789844606

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This book aims to provide readers with the latest updates and an informative overview of the most successful diagnostic aids for periodontal diseases. This book is divided into three sections. Section 1 discusses the periodontal disease pathogenesis and how the disease develops and the contributing factors in disease development. Section 2 includes three chapters that focus mainly on the most common and recent biomarkers that aid in diagnosis of periodontal diseases. Section 3 includes one chapter and discusses a non-surgical treatment modality that could provide definite improvement in the mild to moderate conditions in periodontal diseases.


Salivary Biomakers in Periodontal Health and Disease

Salivary Biomakers in Periodontal Health and Disease
Author: Priyanka N.
Publisher: LAP Lambert Academic Publishing
Total Pages: 76
Release: 2014-11-21
Genre:
ISBN: 9783659625749

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This book provides information on biomarkers found in oral fluids relevant to oral and systemic diseases, with emphasis on salivary molecules and their potential to provide screening diagnosis for periodontal disease. The book will provide greater impact on clinician education in diagnostics, disease-risk and disease prevention through the public health sector before diagnostics will be integrated into routine clinical periodontal practice. Although challenges remain ahead, the use of saliva based oral fluid diagnostics appear promising for future application to diagnose periodontal diseases and to prognosticate periodontal treatment outcomes.


Salivary Diagnostics

Salivary Diagnostics
Author: David T. Wong
Publisher: John Wiley & Sons
Total Pages: 321
Release: 2009-03-16
Genre: Medical
ISBN: 081380664X

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Salivary Diagnostics surveys one of the most exciting areas of research in oral biology. Regarded as the mirror of the body, saliva has immense potential to yield real clinical improvements in our ability to diagnose, and hence treat, oral and systemic conditions. The composition of saliva and other oral fluids reflects the tissue fluid levels of therapeutic, hormonal, and immunological molecules, as well as the presence of markers for systemic and oral disease.


Use of Saliva in Diagnosis of Periodontitis: Cumulative Use of Bacterial and Host-Derived Biomarkers

Use of Saliva in Diagnosis of Periodontitis: Cumulative Use of Bacterial and Host-Derived Biomarkers
Author: Ulvi Kahraman Gürsoy
Publisher: Frontiers Media SA
Total Pages: 107
Release: 2017-03-15
Genre:
ISBN: 2889451240

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Periodontitis is an infection-induced inflammatory disease of the tooth supporting tissues. Treatment of periodontal diseases and regeneration of the effected tissues can be possible only in the early diagnosis of the disease. If left undiagnosed or untreated, periodontitis leads to irreversible soft and hard tissue destruction and finally to tooth loss. Saliva is known to contain inflammatory mediators, host tissue and cell degradation products as well as microbial metabolites and enzymes, reflecting the health status of the oral cavity. In this topic, in collaboration with the well-known scientists working on the field of salivary diagnostics, we demonstrate evidence on monitoring periodontitis by salivary analysis.


Role of Salivary Biomarkers in Periodontal Diseases

Role of Salivary Biomarkers in Periodontal Diseases
Author: Mona Dagar
Publisher: LAP Lambert Academic Publishing
Total Pages: 88
Release: 2014-02-25
Genre:
ISBN: 9783659193149

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Periodontitis is an inflammatory condition of the supporting tissues of the teeth. Intracellular enzymes are increasingly released from the damaged cells of periodontal tissues into the gingival crevicular fluid and saliva. It has been a great challenge to determine biomarkers for screening and predicting the early onset of disease (prognostic tests) or evaluating the disease activity and the efficacy of therapy.Various enzymes evaluated for the early diagnosis of periodontal disease are aspartate and alanine aminotransferases ( AST, ALT ), lactate dehydrogenase ( LDH ), creatine kinase ( CK ), alkaline and acid phosphatase ( ALP, ACP ) and gamma glutamiltransferase ( GGT ), myeloperoxidase ( MPO ). The activities of CK, LDH, AST, ALT, GGT, ALP, ACP, MPO, enzymes are found to be increased in periodontal diseases. Thus, an attempt has been made to review the diagnostic value of salivary enzymes in the diagnosis and progression of periodontal disease.


Interleukin-18 in Periodontal Health and Disease

Interleukin-18 in Periodontal Health and Disease
Author: Parag Hadge
Publisher: LAP Lambert Academic Publishing
Total Pages: 124
Release: 2012
Genre:
ISBN: 9783659175770

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Interleukin (IL) - 18 may be one of the cytokines responsible for initiation and progression of periodontal destruction. IL-18 concentration in gingival crevicular fluid (GCF) and serum increases proportionally with the progression of periodontal disease. Periodontal inflammation may not successfully resolve because of accumulation of IL-18.Periodontal inflammation may not successfully resolve because of accumulation of IL-18. Further, the treatment aimed at arresting periodontal disease progression resulted in statistically significant reduction in the levels of IL-18 both in GCF and serum proportionally. It is very probable that the relatively high levels of IL-18 in GCF in periodontal disease signify it as an important factor in periodontal destruction. Thus, it can be considered as an inflammatory biomarker for periodontal disease and deserves further considerations in the development of preventive and therapeutic methods for treating periodontal disease.


Biomarkers in Periodontal Disease

Biomarkers in Periodontal Disease
Author: Pavan Kumar Addanki
Publisher:
Total Pages: 124
Release: 2018-01-09
Genre:
ISBN: 9783659741975

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Biomarkers of Periodontal Disease and Its Link to Systemic Disease

Biomarkers of Periodontal Disease and Its Link to Systemic Disease
Author: Balwant Rai
Publisher: LAP Lambert Academic Publishing
Total Pages: 296
Release: 2010-08
Genre:
ISBN: 9783838387246

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The first edition of Biomarkers of periodontal disease and its link to systemic disease: BR study group brings to its readers iteration of the unrivalled, supreme work on the specialty of biomarkers and periodontal disease. The authors have written together contributions from own experience to provide the reader with a comprehensive, cohesive text that fuses scholarship and science with clinical and research instruction and practicality. This monograph provided a forum for leading researchers from dental medicine and dental science to present cutting edge research on the linkage between periodontal infections and cardiovascular disease, adverse pregnancy outcomes and diabetes.


Periodontal Diseases: New Insights for the Healthcare Professional: 2011 Edition

Periodontal Diseases: New Insights for the Healthcare Professional: 2011 Edition
Author:
Publisher: ScholarlyEditions
Total Pages: 32
Release: 2012-01-09
Genre: Medical
ISBN: 1464912262

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Periodontal Diseases: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Periodontal Diseases in a compact format. The editors have built Periodontal Diseases: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Periodontal Diseases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Periodontal Diseases: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.