Biology And Treatment Of Leukemia And Bone Marrow Neoplasms PDF Download
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| Author | : Vinod Pullarkat |
| Publisher | : Springer Nature |
| Total Pages | : 200 |
| Release | : 2021-10-09 |
| Genre | : Medical |
| ISBN | : 3030783111 |
Download Biology and Treatment of Leukemia and Bone Marrow Neoplasms Book in PDF, ePub and Kindle
This book provides a concise update on current understanding of the biology of acute and chronic leukemias and other bone marrow neoplasms, including myelodysplastic and myeloproliferative disorders, and explores new and emerging treatments. There is a particular focus on the molecular abnormalities that are drivers of leukemia and on their detection by modern molecular techniques. Knowledge of the ways in which genomic and metabolic abnormalities in the hematologic neoplasms affect prognosis and treatment decision making is reviewed. Detailed attention is devoted to targeted therapies, including novel drugs, and to potential targets for future drug development. In addition, readers find in-depth discussion of cellular and antibody-based immunotherapies as well as the role of hematopoietic stem cell transplantation in the treatment of leukemias and bone marrow malignancies. The book is of special interest for hematologists, oncologists, and cancer researchers; it is also of value for hematology trainees and medical students.
| Author | : Geoffrey Brown |
| Publisher | : MDPI |
| Total Pages | : 199 |
| Release | : 2018-04-17 |
| Genre | : Science |
| ISBN | : 3038427950 |
Download The Biology and Treatment of Myeloid Leukaemias Book in PDF, ePub and Kindle
This book is a printed edition of the Special Issue "The Biology and Treatment of Myeloid Leukaemias" that was published in IJMS
| Author | : James R. Berenson |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 375 |
| Release | : 2004-05-14 |
| Genre | : Medical |
| ISBN | : 159259817X |
Download Biology and Management of Multiple Myeloma Book in PDF, ePub and Kindle
Expert physicians and clinical researchers summarize and explain all the recent advances in the biology and treatment of bone marrow-based malignancy. On the biological side, the authors show the characteristics of the malignant cell and describe the significant roles played by oncogenic changes, chromosomal anomalies, Kaposi's sarcoma herpes virus, and cytokines. New epidemiological findings and prognostic factors are also analyzed. On the clinical side, the authors provide a comprehensive review of conventional treatment regimens, as well as a discussion of newer experimental approaches involving immunologic targeting, inhibitors of drug resistance, and antitumor agents.
| Author | : Anjali S. Advani |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 396 |
| Release | : 2010-11-18 |
| Genre | : Medical |
| ISBN | : 1607617072 |
Download Adult Acute Lymphocytic Leukemia Book in PDF, ePub and Kindle
The current explosion of new areas of controversy in the treatment of acute lymphocytic leukemia in adults and young adults makes this comprehensive book a much needed reference for hematologists and oncologists. This book assembles leading authorities from around the globe to cover the full spectrum of ALL subtypes and their treatments. Specific topics of discussion include indications for allogeneic bone marrow transplant in first complete remission, the role of minimal residual disease in making treatment decisions, the treatment of young adults, and the treatment of Philadelphia chromosome positive ALL with the advent of the tyrosine kinase inhibitors. This is the first book to focus exclusively on the adult ALL patient. It provides a complete overview of diagnosis, molecular pathogenesis, evaluation, and treatment for this important patient population.
| Author | : Srdan Verstovsek |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 233 |
| Release | : 2010-10-17 |
| Genre | : Medical |
| ISBN | : 1607612666 |
Download Myeloproliferative Neoplasms Book in PDF, ePub and Kindle
This succinct resource provides an ideal balance of the biology and practical therapeutic strategies for classic and non-classic BCR-ABL-negative myeloproliferative neoplasms. Utilizing current World Health Organization nomenclature, classification, and diagnostic criteria, international experts have assembled to convey the most up-to-date knowledge in this rapidly evolving field. The opening chapters cover the diagnosis and classification, genetics, cytogenetic findings, and prognostic factors of MPNs. Further chapters explore therapies specific to the different disease entities, including polycythemia vera, essential thrombocytopenia, myelofibrosis, and eosinophilic disorders, and mastocytosis. Unique areas of discussion include JAK2 inhibitor therapy, hematopoietic stem cell transplantation, and blastic transformation. A valuable reference for practicing hematologists, this forefront book enriches our understanding of recent discoveries and their impact on conventional and investigational treatments.
| Author | : Thomas Dittmar |
| Publisher | : CRC Press |
| Total Pages | : 330 |
| Release | : 2016-04-19 |
| Genre | : Medical |
| ISBN | : 1466577363 |
Download Role of Cancer Stem Cells in Cancer Biology and Therapy Book in PDF, ePub and Kindle
This book summarizes the latest findings about the role of cancer stem cells (CSCs) in cancer biology and how this knowledge could be used for novel anticancer therapies. It provides an overview of CSCs in selected malignancies with particular emphasis on hematopoietic neoplasias. It then reviews the role of CSCs in metastasis formation and initiat
| Author | : Laurence H. Baker |
| Publisher | : Springer |
| Total Pages | : 280 |
| Release | : 1985-05-31 |
| Genre | : Gardening |
| ISBN | : |
Download Biology and Therapy of Acute Leukemia Book in PDF, ePub and Kindle
Proceedings of the Seventeenth Annual Detroit Cancer Symposium, held in Detroit, Michigan, April 12-13, 1984
| Author | : |
| Publisher | : Frontiers Media SA |
| Total Pages | : 124 |
| Release | : 2024-04-10 |
| Genre | : Medical |
| ISBN | : 2832547559 |
Download Myeloproliferative Neoplasms: Biology and Treatment Book in PDF, ePub and Kindle
Philadelphia chromosome-negative myeloproliferative neoplasms (MPNs) - including polycythemia vera (PV), essential thrombocythemia (ET) and primary myelofibrosis (PM) - are clonal stem cell disorders characterized by acquired activating mutations which result in an excessive production of red blood cells, platelets, and neutrophils. Recent advances in the understanding of the molecular biology and genomics of MPNs have led to the development of novel targeted treatment approaches; however, the high rate of life-threatening vascular events and the high risk of disease progression with myelofibrotic and leukemic transformation continue to present challenges in the management of MPNs. Thereby, there remains a need for novel treatment strategies. Recently, research has revealed a role for clonal hematopoiesis, driver mutations and inflammation in thrombosis risk, which may provide a basis for novel thrombosis-prevention strategies.
| Author | : Gary J. Schiller |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 325 |
| Release | : 2002-10-16 |
| Genre | : Medical |
| ISBN | : 1592593089 |
Download Chronic Leukemias and Lymphomas Book in PDF, ePub and Kindle
In Chronic Leukemias and Lymphomas: Clinical Management, a panel of recognized experts in hematological oncology describe the unique biological features of indolent hematologic neoplasms, providing powerful insight into their clinical manifestation, highlighting potential targets for novel therapies, and distinguishing these disorders from aggressive lymphoma and Hodgkin's disease. In their integrated surveys of these chronic myeloproliferative and lymphoproliferative disorders, the authors emphasize such unique entities as prolymphocytic leukemias and cutaneous lymphomas. Special emphasis is given to the mechanisms of disease progression with authoritative insights into the promising new era of antineoplastic pharmacology.
| Author | : Franklin O. Smith |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 362 |
| Release | : 2013-11-26 |
| Genre | : Medical |
| ISBN | : 3642399207 |
Download Hematopoietic Cell Transplantation in Children with Cancer Book in PDF, ePub and Kindle
This book is a comprehensive and up-to-date compendium on all aspects of blood and marrow transplantation in children. After an introductory chapter describing the history of pediatric blood and marrow transplantation, subsequent chapters discuss pediatric-specific aspects of transplantation, including stem cell sources suitable for transplantation, preparative regimens, graft-versus-host disease, complications related to transplantation, and late effects. The role of blood and marrow transplantation in various specific pediatric diseases is then examined, and the closing chapter considers future directions. The authors are all internationally recognized experts and offer a largely evidence-based consensus on etiology, biology, and treatment. This handbook has far-reaching applicability to the clinical diagnosis and management of pediatric diseases that are treatable with blood and marrow transplantation and will prove invaluable to specialists, generalists, and trainees alike.
