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Handbook of Biologics for Rheumatological Disorders

Handbook of Biologics for Rheumatological Disorders
Author: Neeraj Jain
Publisher: Springer Nature
Total Pages: 286
Release: 2022-03-06
Genre: Medical
ISBN: 9811672008
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Biologics have revolutionized the treatment of autoimmune diseases due to their efficacy, speed of onset, and tolerability. The development of new agents and expanded use of existing agents continues to be a highly active area of investigation among rheumatic diseases, with a multitude of innovative therapeutic strategies in various stages of development. Although the story of treatments continues rapidly, therapeutic research in some conditions is hindered by the rarity of the disease, variation in phenotype, and concerns about toxicity. This fast-paced development of therapeutics,necessitates immediate evaluation of individual biologic agents and their best use in the new treatment regimens./div This book provides an inclusive approach with the existing evidence concerning effectiveness and implications on the usage of biologics in treating various rheumatologic disorders. It also covers the evidence behind the rational use of these agents in varied autoimmune diseases. This manual also offers a complete overview of the existing & futuristic biologic treatments, and draws recommendations on how to standardize the most suitable regimen for a specific patient in the context of current guidelines. The handbook of Biologics in Rheumatology serves as a present and concise compendium to the modern therapeutic developments in the field./div This book is likely to benefit clinicians, residents, fellow and other healthcare workers dealing with rheumatological disorders, and also hard-core Rheumatologists, who are looking for a quick recap of Biologics of their interest. /div

Biologics for the Treatment of Rheumatoid Arthritis

Biologics for the Treatment of Rheumatoid Arthritis
Author: Ronald van Vollenhoven
Publisher: Springer
Total Pages: 139
Release: 2015-12-22
Genre: Medical
ISBN: 3319131087
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This book provides a comprehensive overview of the available biologic therapies whilst comparing them to standard disease modifying anti-rheumatic drugs, and discusses how best to determine which therapy is most appropriate for an individual patient in the framework of current guidelines. Biologics for the Treatment of Rheumatoid Arthritis is an up-to-date and concise practical guide to the latest therapeutic developments in this field. This book is an invaluable source of topical information for all rheumatologists and health care professionals treating patients with rheumatoid arthritis.

Biologics in Rheumatology

Biologics in Rheumatology
Author: Coziana Ciurtin
Publisher:
Total Pages: 539
Release: 2016
Genre: HEALTH & FITNESS
ISBN: 9781634853026
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Significant progress has been acquired in the treatment of rheumatic conditions with the introduction of biologic therapies, which has enabled better control of disease activity and improved patients' long-term outcome. Apart from several biologic treatments already licensed for use in autoimmune rheumatic conditions, numerous other agents are currently under investigation. This rapid expansion of the therapeutic armamentarium requires a critical analysis of individual biologic options and their clinical indications, in order to facilitate the optimal use of these new therapies. The authors felt that a comprehensive book revisiting all the evidence available regarding the efficacy, cost-effectiveness and health implications of the use of biologics in rheumatology was needed in order to integrate the clinical, ethical and socio-economic aspects related to their use. This book is aimed at specialist doctors, trainees, nurses and health professionals working in the field of rheumatology. It critically appraises the level of evidence behind the use of biologic agents in diverse autoimmune diseases, comprising separate chapters which focus on rheumatoid arthritis, systemic lupus erythematosus, myositis, systemic sclerosis, Sjogren's syndrome, seronegative spondyloarthropathies, psoriatic arthritis and psoriasis, small, medium and large vessel vasculitis, osteoporosis, and interstitial lung disease associated with rheumatic conditions. In addition, the book explores aspects related to the use of biologic agents, such as ethical considerations of consenting patients to take part in clinical trials with biologics, and adolescent and adult rheumatology nurse perspectives related to patients' benefits of biologic therapies. Particular interest is given to the use of biologics during pregnancy and assessment of their infectious risks. A separate chapter explores the off-target benefits associated with the use of anti-TNF therapies. Several chapters include data about cost-effectiveness, and national and international guidelines for the use of biologic agents in different rheumatic conditions.

Biologics in General Medicine

Biologics in General Medicine
Author: W.-H. Boehncke
Publisher: Springer Science & Business Media
Total Pages: 202
Release: 2007-05-08
Genre: Medical
ISBN: 3540290176
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This is the first book to cover every angle in the clinical application of biologics. Readers will not only find that all of the biologics currently approved for clinical use are delineated in a standardized way, but also the "differential therapy" with biologics in fields including dermatology and neurology is described in detail and summarized in treatment algorithms. Shorter sections on biologic biotechnology as well as safety and regulatory issues complement the more clinically-oriented central chapters.

Drug Safety: Managing Innovation in Rheumatology, An Issue of Rheumatic Disease Clinics

Drug Safety: Managing Innovation in Rheumatology, An Issue of Rheumatic Disease Clinics
Author: John J Cush
Publisher: Elsevier Health Sciences
Total Pages: 183
Release: 2012-11-28
Genre: Medical
ISBN: 145575059X
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Edited by Drs. Jack Cush and Kathryn Dao, this issue of Rheumatic Disease Clinics of North America addresses one of the most significant issues facing the rheumatologist today––drug safety in a changing world where rheumatoid arthritis (RA) severity is less, patients are being identified and treated at a very early stage, and prevention is on the horizon. Topics covered include: communicating the risk of side effects, urate-lowering therapies, biphosphonates, biologics, malignancy risks, and administering therapies to patients with co-morbidities.

Early Rheumatoid Arthritis

Early Rheumatoid Arthritis
Author: Paul Emery
Publisher:
Total Pages: 0
Release: 2005
Genre: Rheumatoid arthritis
ISBN: 9781416027676
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This issue covers the latest developments in the understanding of rheumatoid arthritis at the early stage. Treatments such as with newer biologic agents and conventional disease-modifying antirheumatic drugs are reviewed. Also included are articles on imaging modalities as a means of identifying those in the early stages and monitoring response to treatment.

Biologics, Biosimilars, and Biobetters

Biologics, Biosimilars, and Biobetters
Author: Iqbal Ramzan
Publisher: John Wiley & Sons
Total Pages: 328
Release: 2021-02-03
Genre: Medical
ISBN: 1119564654
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A comprehensive primer and reference, this book provides pharmacists and health practitioners the relevant science and policy concepts behind biologics, biosimilars, and biobetters from a practical and clinical perspective. Explains what pharmacists need to discuss the equivalence, efficacy, safety, and risks of biosimilars with physicians, health practitioners, and patients about Guides regulators on pragmatic approaches to dealing with these drugs in the context of rapidly evolving scientific and clinical evidence Balances scientific information on complex drugs with practical information, such as a checklist for pharmacists

Introduction to Basics of Pharmacology and Toxicology

Introduction to Basics of Pharmacology and Toxicology
Author: Abialbon Paul
Publisher: Springer Nature
Total Pages: 1156
Release: 2021-03-13
Genre: Medical
ISBN: 9813360097
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This book explains the pharmacological relationships between the various systems in the human body. It offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems. Presenting up-to-date information on chemical mediators and their significance, it highlights the therapeutic aspects of several diseases affecting the cardiovascular, renal, respiratory, gastrointestinal, endocrinal, and hematopoietic systems. The book also includes drug therapy for microbial and neoplastic diseases. It also comprises sections on immunopharmacology, dermatological, and ocular pharmacology providing valuable insights into these emerging and recent topics. Covering the diverse groups of drugs acting on different systems, the book reviews their actions, clinical uses, adverse effects, interactions, and subcellular mechanisms of action. It is divided into 11 parts, subdivided into several chapters that evaluate the basic pharmacological principles that govern the different types of body systems. This book is intended for academicians, researchers, and clinicians in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry, molecular biology and other allied health sciences.

Skills in Rheumatology

Skills in Rheumatology
Author: Hani Almoallim
Publisher: Springer Nature
Total Pages: 562
Release: 2021-01-05
Genre: Medical
ISBN: 9811583234
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This Open Access book presents practical approaches to managing patients affected by various rheumatological diseases, allowing readers to gain a better understanding of the various clinical expressions and problems experienced by these patients. Discussing rheumatology from an organ systems perspective, it highlights the importance ofdetailed musculoskeletal examinations when treating patients affected by rheumatological diseases. The book first explores the latest diagnostic approaches and offers key tips for accurate musculoskeletal examinations before addressing the various treatment modalities, with a particular focus on the most common joints involved in rheumatoid arthritis: the wrists and the metacarpophalangeal joints (2nd and 3rd). Featuring easy-to-understand flow diagrams and explaining the common medical problems associated with rheumatic disease, such as shortness of breath and anemia, it is not only a valuable resource to rheumatologists, but will also appeal to medical students, junior residents, and primary healthcare physicians.