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Biological Oscillators: Their Mathematical Analysis

Biological Oscillators: Their Mathematical Analysis
Author: Theodosios Pavlidis
Publisher: Elsevier
Total Pages: 222
Release: 2012-12-02
Genre: Science
ISBN: 0323159826
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Biological Oscillators: Their Mathematical Analysis introduces the main features of the dynamic properties of biological oscillators and the mathematical techniques necessary for their investigation. It is not a comprehensive description of all known biological oscillators, since this would require a much bigger volume as well as a different type of expertise. Instead certain classes of biological oscillators are described, and then only in as much detail as required for the study of their dynamics. The opening chapter reviews fundamental mathematical concepts and techniques which will be used in the remainder of the book. These include phase plane techniques; asymptotic techniques of Krylov, Bogoliubov, and Mitopolski; and the describing function. Subsequent chapters discuss examples of biological oscillators; phase shifts and phase response curves; the entrainment of oscillators by external inputs; the dynamics of circadian oscillators; effects of changing environment on the dynamics of biological oscillators; the features peculiar to populations of interacting oscillators; and biological phenomena attributable to populations of oscillators.

Biological Oscillators

Biological Oscillators
Author: Theodosios Pavlidis
Publisher:
Total Pages:
Release: 2012
Genre:
ISBN: 9780125473507
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Biological Oscillators: Their Mathematical Analysis ...

Physics of Biological Oscillators

Physics of Biological Oscillators
Author: Aneta Stefanovska
Publisher: Springer Nature
Total Pages: 431
Release: 2021-05-05
Genre: Science
ISBN: 3030598055
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This book, based on a selection of invited presentations from a topical workshop, focusses on time-variable oscillations and their interactions. The problem is challenging, because the origin of the time variability is usually unknown. In mathematical terms, the oscillations are non-autonomous, reflecting the physics of open systems where the function of each oscillator is affected by its environment. Time-frequency analysis being essential, recent advances in this area, including wavelet phase coherence analysis and nonlinear mode decomposition, are discussed. Some applications to biology and physiology are described. Although the most important manifestation of time-variable oscillations is arguably in biology, they also crop up in, e.g. astrophysics, or for electrons on superfluid helium. The book brings together the research of the best international experts in seemingly very different disciplinary areas.

Oscillations in Mathematical Biology

Oscillations in Mathematical Biology
Author: J.P.E. Hodgson
Publisher: Springer Science & Business Media
Total Pages: 205
Release: 2013-03-13
Genre: Mathematics
ISBN: 3642464807
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The papers in this volume are based on talks given at a one day conference held on the campus of Adelphi University in April 1982. The conference was organized with the title "Oscillations in Mathematical Biology;" however the speakers were allowed considerable latitutde in their choice of topics. In the event, the talks all concerned the dynamics of non-linear systems arising in biology so that the conference achieved a good measure of cohesion. Some of the speakers cho~e not to submit a manuscript for these proceedings, feeling that their material was too conjectural to be committed to print. Also the paper of Rinzel and Troy is a distillation of the two separate talks that the authors gave. Otherwise the material reproduces the conference proceedings. The conference was made possible by the generous support of the Office of the Dean of the College of Arts and Sciences at Adelphi. The bulk of the organization of the conference was carried out by Dr. Ronald Grisell whose energy was in large measure responsible for the success of the conference.

Biological Clocks, Rhythms, and Oscillations

Biological Clocks, Rhythms, and Oscillations
Author: Daniel B. Forger
Publisher: MIT Press
Total Pages: 369
Release: 2024-08-06
Genre: Science
ISBN: 0262552817
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An introduction to the mathematical, computational, and analytical techniques used for modeling biological rhythms, presenting tools from many disciplines and example applications. All areas of biology and medicine contain rhythms, and these behaviors are best understood through mathematical tools and techniques. This book offers a survey of mathematical, computational, and analytical techniques used for modeling biological rhythms, gathering these methods for the first time in one volume. Drawing on material from such disciplines as mathematical biology, nonlinear dynamics, physics, statistics, and engineering, it presents practical advice and techniques for studying biological rhythms, with a common language. The chapters proceed with increasing mathematical abstraction. Part I, on models, highlights the implicit assumptions and common pitfalls of modeling, and is accessible to readers with basic knowledge of differential equations and linear algebra. Part II, on behaviors, focuses on simpler models, describing common properties of biological rhythms that range from the firing properties of squid giant axon to human circadian rhythms. Part III, on mathematical techniques, guides readers who have specific models or goals in mind. Sections on “frontiers” present the latest research; “theory” sections present interesting mathematical results using more accessible approaches than can be found elsewhere. Each chapter offers exercises. Commented MATLAB code is provided to help readers get practical experience. The book, by an expert in the field, can be used as a textbook for undergraduate courses in mathematical biology or graduate courses in modeling biological rhythms and as a reference for researchers.

Physics of Biological Oscillators

Physics of Biological Oscillators
Author: Aneta Stefanovska
Publisher:
Total Pages: 0
Release: 2021
Genre:
ISBN: 9783030598068
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This book, based on a selection of invited presentations from a topical workshop, focusses on time-variable oscillations and their interactions. The problem is challenging, because the origin of the time variability is usually unknown. In mathematical terms, the oscillations are non-autonomous, reflecting the physics of open systems where the function of each oscillator is affected by its environment. Time-frequency analysis being essential, recent advances in this area, including wavelet phase coherence analysis and nonlinear mode decomposition, are discussed. Some applications to biology and physiology are described. Although the most important manifestation of time-variable oscillations is arguably in biology, they also crop up in, e.g. astrophysics, or for electrons on superfluid helium. The book brings together the research of the best international experts in seemingly very different disciplinary areas. .

Mathematical Models in Molecular Cellular Biology

Mathematical Models in Molecular Cellular Biology
Author: Lee A. Segel
Publisher: CUP Archive
Total Pages: 776
Release: 1980
Genre: Mathematics
ISBN: 9780521229258
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Interest in theoretical biology is rapidly growing and this 1981 book attempts to make the theory more accessible to experimentalists. Its primary purpose is to demonstrate to experimental molecular and cellular biologists the possible usefulness of mathematical models. Biologists with a basic command of calculus should be able to learn from the book what assumptions are implied by various types of equations, to understand in broad outline a number of major theoretical concepts, and to be aware of some of the difficulties connected with analytical and numerical solutions of mathematical problems. Thus they should be able to appreciate the significance of theoretical papers in their fields and to communicate usefully with theoreticians in the course of their work.

Mathematical Analysis of Complex Cellular Activity

Mathematical Analysis of Complex Cellular Activity
Author: Richard Bertram
Publisher: Springer
Total Pages: 120
Release: 2015-10-09
Genre: Mathematics
ISBN: 3319181149
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This book contains two review articles on mathematical physiology that deal with closely related topics but were written and can be read independently. The first article reviews the basic theory of calcium oscillations (common to almost all cell types), including spatio-temporal behaviors such as waves. The second article uses, and expands on, much of this basic theory to show how the interaction of cytosolic calcium oscillators with membrane ion channels can result in highly complex patterns of electrical spiking. Through these examples one can see clearly how multiple oscillatory processes interact within a cell, and how mathematical methods can be used to understand such interactions better. The two reviews provide excellent examples of how mathematics and physiology can learn from each other, and work jointly towards a better understanding of complex cellular processes. Review 1: Richard Bertram, Joel Tabak, Wondimu Teka, Theodore Vo, Martin Wechselberger: Geometric Singular Perturbation Analysis of Bursting Oscillations in Pituitary Cells Review 2: Vivien Kirk, James Sneyd: Nonlinear Dynamics of Calcium

Nonlinear Oscillations in Biology and Chemistry

Nonlinear Oscillations in Biology and Chemistry
Author: Hans G. Othmer
Publisher: Springer Science & Business Media
Total Pages: 296
Release: 2013-03-08
Genre: Mathematics
ISBN: 3642933181
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This volume contains the proceedings of a meeting entitled 'Nonlinear Oscillations in Biology and Chemistry', which was held at the University of Utah May 9-11,1985. The papers fall into four major categories: (i) those that deal with biological problems, particularly problems arising in cell biology, (ii) those that deal with chemical systems, (iii) those that treat problems which arise in neurophysiology, and (iv), those whose primary emphasis is on more general models and the mathematical techniques involved in their analysis. Except for the paper by Auchmuty, all are based on talks given at the meeting. The diversity of papers gives some indication of the scope of the meeting, but the printed word conveys neither the degree of interaction between the participants nor the intellectual sparks generated by that interaction. The meeting was made possible by the financial support of the Department of Mathe matics of the University of Utah. I am indebted to Ms. Toni Bunker of the Department of Mathematics for her very able assistance on all manner of details associated with the organization of the meeting. Finally, a word of thanks to all participants for their con tributions to the success of the meeting, and to the contributors to this volume for their efforts in preparing their manuscripts.

Asymptotic Methods for Relaxation Oscillations and Applications

Asymptotic Methods for Relaxation Oscillations and Applications
Author: Johan Grasman
Publisher: Springer Science & Business Media
Total Pages: 229
Release: 2012-12-06
Genre: Science
ISBN: 1461210569
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In various fields of science, notably in physics and biology, one is con fronted with periodic phenomena having a remarkable temporal structure: it is as if certain systems are periodically reset in an initial state. A paper of Van der Pol in the Philosophical Magazine of 1926 started up the investigation of this highly nonlinear type of oscillation for which Van der Pol coined the name "relaxation oscillation". The study of relaxation oscillations requires a mathematical analysis which differs strongly from the well-known theory of almost linear oscillations. In this monograph the method of matched asymptotic expansions is employed to approximate the periodic orbit of a relaxation oscillator. As an introduction, in chapter 2 the asymptotic analysis of Van der Pol's equation is carried out in all detail. The problem exhibits all features characteristic for a relaxation oscillation. From this case study one may learn how to handle other or more generally formulated relaxation oscillations. In the survey special attention is given to biological and chemical relaxation oscillators. In chapter 2 a general definition of a relaxation oscillation is formulated.