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Biological Feedback

Biological Feedback
Author: Rene Thomas
Publisher: CRC Press
Total Pages: 328
Release: 1990-09-25
Genre: Science
ISBN: 9780849367663
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Clearly explaining the logical analysis of biological control phenomena, Biological Feedback answers questions concerning everything from regulation to logic. This rare monograph presents a formal methodology for analyzing the dynamic behavior of complex systems. The easy-to-read text describes a simple logical formalization called "kinetic logic". The reader discovers how this method is used to predict all possible patterns of behavior of which a system is capable. It includes specific conditions required for each pattern. It also explains how to modify an incorrect model in order to account for the observed behavior. The authors give special attention to the two basic types of simple feedback loops: positive and negative. This volume is filled with easy-to-use tables, providing quick reference throughout the book. The subject matter is of great interest to everyone working in molecular genetics and developmental biology. Researchers, immunologists, physical chemists, physicists, electrical engineers, economists, and mathematicians will find this unique text to be an informative, indispensable resource.

Principles of Biological Regulation

Principles of Biological Regulation
Author: Richard Jones
Publisher: Elsevier
Total Pages: 375
Release: 2012-12-02
Genre: Science
ISBN: 0323153534
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Principles of Biological Regulation: An Introduction to Feedback Systems presents some understanding of control, regulatory, and feedback mechanisms in biological systems. This book discusses concepts related to the dynamic behavior of both individual biological processes and systems of processes that make up an organism. Comprised of 10 chapters, the book also describes the characteristics of biological feedback systems, focusing on the physical concepts. After briefly dealing with involved regulatory processes in biological systems, the book goes on discussing the flow or transport of material through a series of processes in the steady-state. Next chapter uses superposition principle to explain the changes that biological systems undergo following a disturbance or under dynamic behavior. The subsequent chapters cover the fundamental principles of negative biological feedback and to the effects it produces both under steady-state and dynamic behavior. Other chapters describe the effect of sinusoid signals on biological processes and present some stability criteria applied to technological systems and also their value in the study of homeostatic processes. The book also discusses some aspects of homeostats that seem to distinguish them from technological feedback systems. These features include not only the components themselves and their organization, but also the experimental problems involved in their study. The concluding chapters describe nonlinear behavior with great relevance to homeostatic systems and rate processes (production or destruction) for which the roles of stimulus and initial conditions are different. Mathematical relations developed from the conservation of mass and the mass action for chemical reactions are also presented. The book is an invaluable resource for life scientists and researchers.

Biological Clocks, Rhythms, and Oscillations

Biological Clocks, Rhythms, and Oscillations
Author: Daniel B. Forger
Publisher: MIT Press
Total Pages: 369
Release: 2024-08-06
Genre: Science
ISBN: 0262552817
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An introduction to the mathematical, computational, and analytical techniques used for modeling biological rhythms, presenting tools from many disciplines and example applications. All areas of biology and medicine contain rhythms, and these behaviors are best understood through mathematical tools and techniques. This book offers a survey of mathematical, computational, and analytical techniques used for modeling biological rhythms, gathering these methods for the first time in one volume. Drawing on material from such disciplines as mathematical biology, nonlinear dynamics, physics, statistics, and engineering, it presents practical advice and techniques for studying biological rhythms, with a common language. The chapters proceed with increasing mathematical abstraction. Part I, on models, highlights the implicit assumptions and common pitfalls of modeling, and is accessible to readers with basic knowledge of differential equations and linear algebra. Part II, on behaviors, focuses on simpler models, describing common properties of biological rhythms that range from the firing properties of squid giant axon to human circadian rhythms. Part III, on mathematical techniques, guides readers who have specific models or goals in mind. Sections on “frontiers” present the latest research; “theory” sections present interesting mathematical results using more accessible approaches than can be found elsewhere. Each chapter offers exercises. Commented MATLAB code is provided to help readers get practical experience. The book, by an expert in the field, can be used as a textbook for undergraduate courses in mathematical biology or graduate courses in modeling biological rhythms and as a reference for researchers.

Positive Feedback in Natural Systems

Positive Feedback in Natural Systems
Author: Donald Lee DeAngelis
Publisher: Springer Verlag
Total Pages: 0
Release: 1986
Genre: Science
ISBN: 9780387159423
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The Biological Foundations of Action

The Biological Foundations of Action
Author: Derek M Jones
Publisher: Routledge
Total Pages: 181
Release: 2016-07-01
Genre: Philosophy
ISBN: 1317196023
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Philosophers have traditionally assumed that the difference between active and passive movement could be explained by the presence or absence of an intention in the mind of the agent. This assumption has led to the neglect of many interesting active behaviors that do not depend on intentions, including the "mindless" actions of humans and the activities of non-human animals. In this book Jones offers a broad account of agency that unifies these cases. The book addresses a range of questions, including: When are movements properly attributed to whole agents, rather than to their parts? What does it mean for an agent to guide its action? What distinguishes agents from other complex systems? What is the relationship between action and adaptive behavior? And why might the study of living systems be the key to understanding agency? This book makes an important contribution to current philosophical debate on the nature and origins of agency. It defines action as a uniquely biological process and recasts human intentional action as a specialized case of a broader and more common phenomenon than has been previously assumed. Uniting findings from philosophy, cognitive science, psychology, biology, computer science, complexity theory and ethology, this book will be of interest to students and scholars working in these areas.

Positive Feedback in Natural Systems

Positive Feedback in Natural Systems
Author: Donald L. DeAngelis
Publisher: Springer Science & Business Media
Total Pages: 292
Release: 2012-12-06
Genre: Mathematics
ISBN: 3642826253
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Cybernetics, a science concerned with understanding how systems are regulated, has reflected the preoccupations of the century in which it was born. Regulation is important in twentieth century society, where both machines and social organizations are complex. Cybernetics focused on and became primarily associated with the homeostasis or stability of system behavior and with the negative feedbacks that stabilize systems. It paid less attention to the processes opposite to negative feedback, the positive feedback processes that act to change systems. We attempt to redress the balance here by illustrating the enormous importance of positive feedbacks in natural systems. In an article in the American Scientist in 1963, Maruyama called for increased attention to this topic, noting that processes of change could occur when a "deviation in anyone component of the system caused deviations in other components that acted back on the first component to reinforce of amplify the initial deviation." The deviation amplification is the result of positive feedback among system components. Maruyama demonstrated by numerous examples that the neglect of such processes was unjustified and suggested that a new branch of cybernetics, "the second cybernetics," be devoted to their study.

Population Homeostasis

Population Homeostasis
Author: Christopher J. Paradise
Publisher: Momentum Press
Total Pages: 55
Release: 2016-04-27
Genre: Science
ISBN: 1606509764
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This book will synthesize the concepts of selection against individuals in response to environmental change to illustrate how selection against individuals results in homeostasis at the population level. For instance, selection against the light phenotype of the peppered moth during the early part of the industrial revolution led to an increase of the dark phenotype, which was better camouflaged against the soot that accumulated on tree bark as a result of burning coal. Populations are shown to be regulated by feedback mechanisms, several of which are discussed here. Populations are regulated by extrinsic factors, such as competition and predation, and that lead to changes in intrinsic factors, such as reproduction. Changes in population density often lead to initiation of feedback mechanisms, such as changes in birth or death rates. In a final example, pollutants are shown to be a factor that can disrupt homeostasis of populations. In particular, populations of top predators, such as raptors, have suffered due to bio­magnification of toxins.

Biological Robustness

Biological Robustness
Author: Marta Bertolaso
Publisher: Springer
Total Pages: 258
Release: 2019-01-04
Genre: Philosophy
ISBN: 3030011984
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This volume reviews examples and notions of robustness at several levels of biological organization. It tackles many philosophical and conceptual issues and casts an outlook on the future challenges of robustness studies in the context of a practice-oriented philosophy of science. The focus of discussion is on concrete case studies. These highlight the necessity of a level-dependent description of robust biological behaviors.Experts from the neurosciences, biochemistry, ecology, biology, and the history and the philosophy of life sciences provide a multiplex perspective on the topic. Contributions span from protein folding, to cell-level robustness, to organismal and developmental robustness, to sensorimotor systems, up to the robustness of ecological systems.Several chapters detail neurobiological case-studies. The brain, the poster child of plasticity in biology, offers multiple examples of robustness. Neurobiology explores the importance of temporal organization and multiscalarity in making this robustness-with-plasticity possible. The discussion also includes structures well beyond the brain, such as muscles and the complex feedback loops involved in the peculiar robustness of music perception. Overall, the volume grounds general reflections upon concrete case studies, opening to all the life sciences but also to non-biological and bio-inspired fields such as post-modern engineering. It will appeal to researchers, students, as well as non-expert readers.

Biological Determinants of Reinforcement

Biological Determinants of Reinforcement
Author: Michael L. Commons
Publisher: Psychology Press
Total Pages: 314
Release: 1988
Genre: Art
ISBN: 9780898595512
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First Published in 1988. Routledge is an imprint of Taylor & Francis, an informa company.