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Biological Effects of Cholesterol Oxides

Biological Effects of Cholesterol Oxides
Author: Shi-Kaung Peng
Publisher: CRC Press
Total Pages: 222
Release: 1991-11-22
Genre: Medical
ISBN: 9780849367762

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In recent years, researchers have accumulated a growing body of evidence linking cholesterol oxides with human diseases such as atherosclerosis and cancer. This book presents what is presently known about the biological activities of cholesterol oxides and is intended to stimulate thinking in new areas of diet-heart or diet-cancer research. Topics discussed include the oxidation of cholesterol, methods of analysis of cholesterol oxides, cholesterol oxide content in foods, effects of cholesterol oxides on cell membranes, and cytotoxicity of cholesterol oxides. The book will be an essential reference source for researchers working directly with cholesterol and cholesterol oxides, as well as researchers concerned with the wider aspects of chemistry, biology, and medicine.


Cholesterol and Phytosterol Oxidation Products

Cholesterol and Phytosterol Oxidation Products
Author: Francesc Guardiola
Publisher: The American Oil Chemists Society
Total Pages: 408
Release: 2002-07-30
Genre: Medical
ISBN: 9781893997349

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This book comprehensively reviews several aspects of cholesterol oxidation products: cholesterol oxidation mechanisms, analytical determination, origin and content of these compounds in foods and biological samples, and their biological effects, with an emphasis on recent advances in these fields. Information on different aspects of phytosterol oxidation is reviewed. Little research has been conducted on the analysis of mixed sterol oxidation products. Mixed diets containing both cholesterol and phytosterols can contain a complex array of oxidation products generated from these sterols. Research into the problem of analyzing these complex mixtures of compounds is highlighted.


Lipid Oxidation

Lipid Oxidation
Author: Edwin N. Frankel
Publisher: Elsevier
Total Pages: 487
Release: 2014-01-23
Genre: Technology & Engineering
ISBN: 085709792X

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In this second edition, Edwin Frankel has updated and extended his now well-known book Lipid oxidation which has come to be regarded as the standard work on the subject since the publication of the first edition seven years previously. His main objective is to develop the background necessary for a better understanding of what factors should be considered, and what methods and lipid systems should be employed, to achieve suitable evaluation and control of lipid oxidation in complex foods and biological systems. The oxidation of unsaturated fatty acids is one of the most fundamental reactions in lipid chemistry. When unsaturated lipids are exposed to air, the complex, volatile oxidation compounds that are formed cause rancidity. This decreases the quality of foods that contain natural lipid components as well as foods in which oils are used as ingredients. Furthermore, products of lipid oxidation have been implicated in many vital biological reactions, and evidence has accumulated to show that free radicals and reactive oxygen species participate in tissue injuries and in degenerative disease. Although there have been many significant advances in this challenging field, many important problems remain unsolved. This second edition of Lipid oxidation follows the example of the first edition in offering a summary of the many unsolved problems that need further research. The need to understand lipid oxidation is greater than ever with the increased interest in long-chain polyunsaturated fatty acids, the reformulation of oils to avoid hydrogenation and trans fatty acids, and the enormous attention given to natural phenolic antioxidants, including flavonoids and other phytochemicals.


Autoxidation in Food and Biological Systems

Autoxidation in Food and Biological Systems
Author: M.G. Simic
Publisher: Springer Science & Business Media
Total Pages: 652
Release: 2013-06-29
Genre: Technology & Engineering
ISBN: 1475793510

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The material presented in this book deals with basic mechanisms of free radical reactions in autoxidation processes and anitoxidant suppression of autoxidation of foods, biochemical models and biologi cal systems. Autoxidation in foods and corresponding biological effects are usually approached separately although recent mechanistic developments in the biochemistry and free radical chemistry of per oxides and their precursors tend to bring these two fields closer. Apparent ability of antioxidants in diets to reduce the inci dence of cancer has resulted in scrutiny of autoxidized products and their precursors as possibly toxic, mutagenic and carcinogenic agents. Mechanisms of any of these effects have been barely ad dressed. Yet we know now that free radicals, as esoteric as they were only a few decades ago, are being discovered in foods, biochem ical and biological systems and do play a role in the above-mentioned causalities. The purpose of the Workshop and the resulting book was to give a unifying approach towards study of beneficial and deleterious effects of autoxidation, based on rigorous scientific considerations. It is our hope that the material presented in this book will not only provide a review of the "state of the art" of autoxidation and anti oxidants, but also reflect the interaction which occurred during the Workshop between workers using model sytems, and food and biological systems.


Diet and Health

Diet and Health
Author: National Research Council
Publisher: National Academies Press
Total Pages: 765
Release: 1989-01-01
Genre: Medical
ISBN: 0309039940

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Diet and Health examines the many complex issues concerning diet and its role in increasing or decreasing the risk of chronic disease. It proposes dietary recommendations for reducing the risk of the major diseases and causes of death today: atherosclerotic cardiovascular diseases (including heart attack and stroke), cancer, high blood pressure, obesity, osteoporosis, diabetes mellitus, liver disease, and dental caries.


Methods in Membrane Lipids

Methods in Membrane Lipids
Author: Alex M. Dopico
Publisher: Springer Science & Business Media
Total Pages: 1265
Release: 2007-08-30
Genre: Medical
ISBN: 1588296628

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This book presents a compendium of methodologies for the study of membrane lipids, varying from traditional lab bench experimentation to computer simulation and theoretical models. The volume provides a comprehensive set of techniques for studying membrane lipids with a strong biophysical emphasis. It compares the various available techniques including the pros and cons as seen by the experts.


Phytosterols as Functional Food Components and Nutraceuticals

Phytosterols as Functional Food Components and Nutraceuticals
Author: Paresh C. Dutta
Publisher: CRC Press
Total Pages: 460
Release: 2003-12-02
Genre: Technology & Engineering
ISBN: 1135520259

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Analyzes food and biological samples of phytosterols and discusses plant sterol analysis with respect to functional foods. Investigates the safety of phytosterols and phytosterol esters and associated health risks, including potential impact on cancer development and the lowering of cholesterol levels. Details the chemistry, occurrence, and biological effects of phytosterol oxides.