Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Biodegradable Star Shaped Block Copolymer Hydrogels For Drug Delivery PDF full book. Access full book title Biodegradable Star Shaped Block Copolymer Hydrogels For Drug Delivery.
| Author | : Young Kweon Choi |
| Publisher | : |
| Total Pages | : 458 |
| Release | : 1996 |
| Genre | : Block copolymers |
| ISBN | : |
| Author | : Haesun Park |
| Publisher | : CRC Press |
| Total Pages | : 272 |
| Release | : 2011-07-08 |
| Genre | : Medical |
| ISBN | : 9781439892961 |
From the Authors' Preface The advances made in the area of controlled drug delivery during the last two decades are remarkable ....Of the many polymeric materials, biodegradable hydrogels present unique advantages and opportunities in the development of ...delivery devices....We have undertaken the challenge of putting together information relevant to biodegradable hydrogels in one place. This book covers the mechanisms of biodegradation, types of biodegradable hydrogels,chemical and physical gels, chemical and enzymatic degradation, and examples of biodegradable drug delivery systems.
| Author | : Xian Jun Loh |
| Publisher | : Royal Society of Chemistry |
| Total Pages | : 198 |
| Release | : 2018-09-27 |
| Genre | : Science |
| ISBN | : 1782629408 |
Biodegradable thermogels are a promising class of stimuli-responsive polymers. This book summarizes recent developments in thermogel research with a focus on synthesis and self-assembly mechanisms, gel biodegradability, and applications for drug delivery, cell encapsulation and tissue engineering. A closing chapter on commercialisation shows the challenges faced bringing this new material to market. Edited by leading authorities on the subject, this book offers a comprehensive overview for academics and professionals across polymer science, materials science and biomedical and chemical engineering.
| Author | : |
| Publisher | : Academic Press |
| Total Pages | : 810 |
| Release | : 2018-11-30 |
| Genre | : Business & Economics |
| ISBN | : 0128179104 |
Basic Fundamentals of Drug Delivery covers the fundamental principles, advanced methodologies and technologies employed by pharmaceutical scientists, researchers and pharmaceutical industries to transform a drug candidate or new chemical entity into a final administrable drug delivery system. The book also covers various approaches involved in optimizing the therapeutic performance of a biomolecule while designing its appropriate advanced formulation. Provides up-to-date information on translating the physicochemical properties of drugs into drug delivery systems Explores how drugs are administered via various routes, such as orally, parenterally, transdermally or through inhalation Contains extensive references and further reading for course and self-study
| Author | : Raphael M. Ottenbrite |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 438 |
| Release | : 2010-09-05 |
| Genre | : Technology & Engineering |
| ISBN | : 144195919X |
Hydrogels are networks of polymer chains which can produce a colloidal gel containing over 99 per cent water. The superabsorbency and permeability of naturally occurring and synthetic hydrogels give this class of materials an amazing array of uses. These uses range from wound dressings and skin grafts to oxygen-permeable contact lenses to biodegradable delivery systems for drugs or pesticides and scaffolds for tissue engineering and regenerative medicine. Biomedical Applications of Hydrogels Handbook provides a comprehensive description of this diverse class of materials, covering both synthesis and properties and a broad range of research and commercial applications. The Handbook is divided into four sections: Stimuli-Sensitive Hydrogels, Hydrogels for Drug Delivery, Hydrogels for Tissue Engineering, and Hydrogels with Unique Properties. Key Features: Provides comprehensive coverage of the basic science and applications of a diverse class of materials Includes both naturally occurring and synthetic hydrogels Edited and written by world leaders in the field.
| Author | : Mahdi Karimi |
| Publisher | : Morgan & Claypool Publishers |
| Total Pages | : 112 |
| Release | : 2015-12-01 |
| Genre | : Science |
| ISBN | : 1681742578 |
The concept of smart drug delivery vehicles involves designing and preparing a nanostructure (or microstructure) that can be loaded with a cargo. This can be a therapeutic drug, a contrast agent for imaging, or a nucleic acid for gene therapy. The nanocarrier serves to protect the cargo from degradation by enzymes in the body, to enhance the solubility of insoluble drugs, to extend the circulation half-life, and to enhance its penetration and accumulation at the target site. Importantly, smart nanocarriers can be designed to be responsive to a specific stimulus, so that the cargo is only released or activated when desired. In this volume we cover smart nanocarriers that respond to internal stimuli that are intrinsic to the target site. These stimuli are specific to the cell type, tissue or organ type, or to the disease state (cancer, infection, inflammation etc). pH-responsive nanostructures can be used for cargo release in acidic endosomal compartments, in the lower pH of tumors, and for specific oral delivery either to the stomach or intestine. Nanocarriers can be designed to be substrates of a wide-range of enzymes that are over-expressed at disease sites. Oxidation and reduction reactions can be taken advantage of in smart nanocarriers by judicious molecular design. Likewise, nanocarriers can be designed to respond to a range of specific biomolecules that may occur at the target site. In this volume we also cover dual and multi-responsive systems that combine stimuli that could be either internal or external.
| Author | : Timothy T. Nguyen |
| Publisher | : |
| Total Pages | : 105 |
| Release | : 2012 |
| Genre | : Drug delivery systems |
| ISBN | : |
Polymeric delivery vehicles of increasing complexity and design have been envisioned for use in medical applications that involve in vivo delivery of exogenous material. Nanogel star polymers are monodispersed molecules that possess a high number of end groups and tunability. Therefore, customizable star polymers are potential candidates for biomedical applications. This thesis describes the first use of organocatalytic ring-opening polymerization (ROP) as a general route by which to synthesize nanogel star polymers that have a controlled size, biodegradability, polyvalency, dense poly(ethylene glycol) (PEG) surface coverage, and hydrophobic core. Two synthetic methods were used to determine the most effective means of synthesizing the star polymers. These polymers underwent characteration experiments with a focus on functionality, uptake and release of hydrophobic material under physiological conditions, and particle size. Star polymers have achieved targeted hydrodynamic radius of 10 nm with polydispersity of 1.2. By utilizing degradable star polymers as a carrier molecule, other useful agents, such as pharmaceutical drugs or probes, can be embedded into the star polymer via self-assembled occlusion complex formation. The amount of material that were shown to be embedded into these polymers were between 20 and 40 Nile Red particles per star polymer particle. This ability, in conjunction with peptide peripheral functionality, provided star polymers with a means for targeting specific sites and allowed these particles future usage as nanoscale delivery vehicles.
| Author | : Nikolaos A. Peppas |
| Publisher | : CRC Press |
| Total Pages | : 191 |
| Release | : 2019-08-15 |
| Genre | : Medical |
| ISBN | : 1000693864 |
First Published in 1986, this book offers a full, comprehensive guide to the application of hydrogels in medicine. Carefully compiled and filled with a vast repertoire of notes, diagrams, and references this book serves as a useful reference for students of medicine and other practitioners in their respective fields.
| Author | : Umile Gianfranco Spizzirri |
| Publisher | : CRC Press |
| Total Pages | : 362 |
| Release | : 2017-08-10 |
| Genre | : Medical |
| ISBN | : 149874902X |
The book deals with the synthesis and characterization of hydrogels specifically used as drug delivery systems. Each chapter includes the most recent updates about the different starting materials employed and the improvement of their physicochemical and biological properties to synthetize high performing carriers for specific uses.
| Author | : Jun Li |
| Publisher | : Springer |
| Total Pages | : 163 |
| Release | : 2018-07-17 |
| Genre | : Technology & Engineering |
| ISBN | : 3662575116 |
This book introduces readers to the latest advances in hydrogel biomaterials, mainly focusing on the emerging areas of synthetic and biopolymer hydrogels formed through specially designed chemical or physical crosslinking, and the cyclodextrin-based host-guest supramolecular self-assembly, for cell encapsulation, cell expansion, cell differentiation and tissue repair, stem cell culture, and cellular therapy and drug delivery applications. The book was written by experts at the forefront of these interdisciplinary areas and is intended for all researchers working in the fields of biomaterials and biomedical engineering, as well as medical professions. Jun Li is a Professor at the Department of Biomedical Engineering, National University of Singapore, Singapore. Yoshihito Osada is a Professor at RIKEN Advanced Science Institute, Japan. Justin Cooper-White is a Professor at the Australian Institute for Bioengineering and Nanotechnology, University of Queensland, Australia.
