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Biocatalysts and Enzyme Technology

Biocatalysts and Enzyme Technology
Author: Klaus Buchholz
Publisher: John Wiley & Sons
Total Pages: 609
Release: 2012-12-21
Genre: Science
ISBN: 3527672001

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This second edition of a bestselling textbook offers an instructive and comprehensive overview of our current knowledge of biocatalysis and enzyme technology. The book now contains about 40% more printed content. Three chapters are completely new, while the others have been thoroughly updated, and a section with problems and solutions as well as new case studies have been added. Following an introduction to the history of enzyme applications, the text goes on to cover in depth enzyme mechanisms and kinetics, production, recovery, characterization and design by protein engineering. The authors treat a broad range of applications of soluble and immobilized biocatalysts, including wholecell systems, the use of non-aqueous reaction systems, applications in organic synthesis, bioreactor design and reaction engineering. Methods to estimate the sustainability, important internet resources and their evaluation, and legislation concerning the use of biocatalysts are also covered.


Biocatalysis and Biocatalytic Technologies

Biocatalysis and Biocatalytic Technologies
Author: Gennadiĭ Efremovich Zaikov
Publisher: Nova Publishers
Total Pages: 98
Release: 2006
Genre: Science
ISBN: 9781600210419

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This book covers the application, both actual and potential, of biological catalysts (including whole cells or isolated components thereof, natural and modified enzymes and catalytic antibodies) for the synthesis, interconversion or degradation of chemical species.


Biocatalysis for Practitioners

Biocatalysis for Practitioners
Author: Gonzalo de Gonzalo
Publisher: John Wiley & Sons
Total Pages: 54
Release: 2021-07-19
Genre: Science
ISBN: 352734683X

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This reference book originates from the interdisciplinary research cooperation between academia and industry. In three distinct parts, latest results from basic research on stable enzymes are explained and brought into context with possible industrial applications. Downstream processing technology as well as biocatalytic and biotechnological production processes from global players display the enormous potential of biocatalysts. Application of "extreme" reaction conditions (i.e. unconventional, such as high temperature, pressure, and pH value) - biocatalysts are normally used within a well defined process window - leads to novel synthetic effects. Both novel enzyme systems and the synthetic routes in which they can be applied are made accessible to the reader. In addition, the complementary innovative process technology under unconventional conditions is highlighted by latest examples from biotech industry.


Biocatalysis

Biocatalysis
Author: Andreas S. Bommarius
Publisher: John Wiley & Sons
Total Pages: 634
Release: 2007-02-27
Genre: Science
ISBN: 352760605X

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The whole range of biocatalysis, from a firm grounding in theoretical concepts to in-depth coverage of practical applications and future perspectives. The book not only covers reactions, products and processes with and from biological catalysts, but also the process of designing and improving such biocatalysts. One unique feature is that the fields of chemistry, biology and bioengineering receive equal attention, thus addressing practitioners and students from all three areas.


Nanomaterials for Biocatalysis

Nanomaterials for Biocatalysis
Author: Guillermo R. Castro
Publisher: Elsevier
Total Pages: 754
Release: 2021-10-14
Genre: Technology & Engineering
ISBN: 0128244364

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Nanomaterials for Biocatalysis explains the fundamental design concepts and emerging applications of nanoscale biocatalysts, such as bioconversions, bioelectronics, biosensors, biocomputing and therapeutic applications. Nano-biocatalysts refers to the incorporation of enzymes into nanomaterials. These enzyme-enhanced nanocarriers have many advantages, including low mass transfer limitation, high enzyme capacity, better stabilization, and the formation of single-enzyme nanoparticles. Smart nanocontainers have been developed for the smart release of their embedded active substances. These smart releases can be obtained by using smart coatings as their outer nanoshells. In addition, these nanocontainers could protect the enzymes from chemical or metabolic alterations on their delivering pathways towards the target. This is an important reference source for materials scientists and chemical engineers who want to know more about how nanomaterials are being used for biocatalysis applications. Explains the major fabrication techniques and applications of nanobiocatalysts Shows how nanobiocatalysts are used in a variety of environmental and biomedical sectors Assesses the major challenges associated with the widespread manufacture of nanobiocatalysts


Applied Biocatalysis

Applied Biocatalysis
Author: Lutz Hilterhaus
Publisher: John Wiley & Sons
Total Pages: 464
Release: 2016-09-13
Genre: Science
ISBN: 3527336699

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This reference book originates from the interdisciplinary research cooperation between academia and industry. In three distinct parts, latest results from basic research on stable enzymes are explained and brought into context with possible industrial applications. Downstream processing technology as well as biocatalytic and biotechnological production processes from global players display the enormous potential of biocatalysts. Application of "extreme" reaction conditions (i.e. unconventional, such as high temperature, pressure, and pH value) - biocatalysts are normally used within a well defined process window - leads to novel synthetic effects. Both novel enzyme systems and the synthetic routes in which they can be applied are made accessible to the reader. In addition, the complementary innovative process technology under unconventional conditions is highlighted by latest examples from biotech industry.


Technological Applications of Biocatalysts

Technological Applications of Biocatalysts
Author:
Publisher:
Total Pages: 434
Release: 1993
Genre: Medical
ISBN:

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This book builds upon a knowledge of the properties of enzymes and shows how these important catalysts can be used in industry. The central theme demonstrates how proteins, especially enzymes and immunoglobins can be isolated, characterised and produced on a large scale. Specific examples are given and both practical and theoretical aspects are examined. Applications for a wide range of metabolites are described with particular emphasis on the design, performance and production of biosensors. * Step-by-step logical development * Student centered learning style * Texts planned by both industry and academia The need for a cost effective training scheme for new and existing staff at all levels has been met by the University of Greenwich (formerly Thames Polytechnic) and the Open University of the Netherlands. As part of the European Community Education and Technology Training initiative (COMETT) and in conjunction with a number of other leading UK and European universities, they are developing BIOTOL, a training scheme in biotechnology using open learning materials, which will provide tailor-made courses, flexible in content, pace and place. 'This is a particularly useful learning resource for people wanting to broaden their knowledge in biotechnology either informally or by extending their formal education in MScs and similar courses.' - Journal of Chemical Tech & Biotechnology, July 1995


Practical Methods for Biocatalysis and Biotransformations 2

Practical Methods for Biocatalysis and Biotransformations 2
Author: John Whittall
Publisher: John Wiley & Sons
Total Pages: 392
Release: 2012-04-16
Genre: Technology & Engineering
ISBN: 1119943418

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Biocatalysts are increasingly used by chemists engaged in fine chemical synthesis within both industry and academia. Today, there exists a huge choice of high-tech enzymes and whole cell biocatalysts, which add enormously to the repertoire of synthetic possibilities. Practical Methods for Biocatalysis and Biotransformations 2 is a "how-to" guide that focuses on the practical applications of enzymes and strains of microorganisms that are readily obtained or derived from culture collections. The sources of starting materials and reagents, hints, tips and safety advice (where appropriate) are given to ensure, as far as possible, that the procedures are reproducible. Comparisons to alternative methodology are given and relevant references to the primary literature are cited. This second volume – which can be used on its own or in combination with the first volume - concentrates on new applications and new enzyme families reported since the first volume. Contents include: introduction to recent developments and future needs in biocatalysts and synthetic biology in industry reductive amination enoate reductases for reduction of electron deficient alkenes industrial carbonyl reduction regio- and stereo- selective hydroxylation oxidation of alcohols selective oxidation industrial hydrolases and related enzymes transferases for alkylation, glycosylation and phosphorylation C-C bond formation and decarboxylation halogenation/dehalogenation/heteroatom oxidation tandem and sequential multi-enzymatic syntheses Practical Methods for Biocatalysis and Biotransformations 2 is an essential collection of biocatalytic methods for chemical synthesis which will find a place on the bookshelves of synthetic organic chemists, pharmaceutical chemists, and process R&D chemists in industry and academia.


Practical Methods for Biocatalysis and Biotransformations 3

Practical Methods for Biocatalysis and Biotransformations 3
Author: John Whittall
Publisher: John Wiley & Sons
Total Pages: 320
Release: 2016-02-16
Genre: Technology & Engineering
ISBN: 1118696298

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Biocatalysts are increasingly used by chemists engaged in fine chemical synthesis within both industry and academia. Today, there exists a huge choice of high-tech enzymes and whole cell biocatalysts, which add enormously to the repertoire of synthetic possibilities. Practical Methods for Biocatalysis and Biotransformations 3 will be a companion book to Practical Methods for Biocatalysis and Biotransformations (2009) and Practical Methods for Biocatalysis and Biotransformations 2 (2012). Following the successful format of the two volumes, it will be a “how-to” guide focusing on commercially available enzymes and strains of microorganisms that are readily obtained from culture collections. The source of starting materials and reagents, hints, tips and safety advice (where appropriate) will be given to ensure, as far as possible, that the procedures are reproducible. Comparisons to alternative methodology will be given and relevant references to the primary literature will be cited. Contents include: Biotransformation Process Technology Industrial Biooxidation Hydrolase catalysed hydrolysis/synthesis Reduction Oxidation Halogenation Transferase catalysed glycosylation, methylation, etc C-C bond formation Tandem Biocatalytic Reactions Practical Methods for Biocatalysis and Biotransformations, Volume 3 is an essential collection of validated biocatalytic methods which will find a place on the bookshelves of synthetic organic chemists, pharmaceutical chemists, and process R&D chemists in industry and academia.


Enzyme Technologies

Enzyme Technologies
Author: Wu-Kuang Yeh
Publisher: John Wiley & Sons
Total Pages: 388
Release: 2011-09-28
Genre: Science
ISBN: 0470627298

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An authoritative review of the latest developments in the chemical biology of enzymes In the first decade of the twenty-first century, enzymes and their multiple applications have played a critical role in the discovery and development of many new therapeutic agents.This book is a coordinated compilation of research expertise and current opinion uniquely focused on enzymes and their properties and applications. Compiled by editors with a combined pharmaceutical experience of over sixty years, the text provides in-depth reviews of recent developments in selective topics on biosynthesis, biocatalysis, and chemical biology of enzymes as it applies to drug discovery, development, and manufacture. The first in a multi-part series on enzymes, this volume features three sections: New Approaches to Find and Modify Enzymes describes the emerging field of metagenomics, presents the practical applications of directed evolution to enzymes and pathways, and explores approaches for the discovery and design of biocatalysts Biocatalytic Applications reviews specific applications of different reactions in producing active pharmaceutical ingredients and surveys recent developments employing enzymes in organic synthesis Biosynthetic Applications goes over successful drug discoveries and developments by combinatorial biosynthesis and reviews the application of combinatorial biosynthesis among multiple compatible hosts These timely discussions, which cover everything from chemical biology of enzymes, to the redesign of binding and catalytic specificities of enzymes, make this volume a valuable tool for keeping up to date. As such, it is an important read for researchers, students, and professors in the study of biotechnology, life sciences, biochemistry, enzymology, medicinal chemistry, and natural products.