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Cochrane Handbook for Systematic Reviews of Interventions

Cochrane Handbook for Systematic Reviews of Interventions
Author: Julian P. T. Higgins
Publisher: Wiley
Total Pages: 672
Release: 2008-11-24
Genre: Medical
ISBN: 9780470699515

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Healthcare providers, consumers, researchers and policy makers are inundated with unmanageable amounts of information, including evidence from healthcare research. It has become impossible for all to have the time and resources to find, appraise and interpret this evidence and incorporate it into healthcare decisions. Cochrane Reviews respond to this challenge by identifying, appraising and synthesizing research-based evidence and presenting it in a standardized format, published in The Cochrane Library (www.thecochranelibrary.com). The Cochrane Handbook for Systematic Reviews of Interventions contains methodological guidance for the preparation and maintenance of Cochrane intervention reviews. Written in a clear and accessible format, it is the essential manual for all those preparing, maintaining and reading Cochrane reviews. Many of the principles and methods described here are appropriate for systematic reviews applied to other types of research and to systematic reviews of interventions undertaken by others. It is hoped therefore that this book will be invaluable to all those who want to understand the role of systematic reviews, critically appraise published reviews or perform reviews themselves.


Selection Bias and Covariate Imbalances in Randomized Clinical Trials

Selection Bias and Covariate Imbalances in Randomized Clinical Trials
Author: Vance Berger
Publisher: John Wiley & Sons
Total Pages: 218
Release: 2007-10-22
Genre: Mathematics
ISBN: 0470863633

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Selection bias can, and does, occur, even in randomized clinical trials. Steps need to be taken in order to ensure that this does not compromise the integrity of clinical trials; hence “Selection Bias and Covariate Imbalances in Randomized Clinical Trials” offers a comprehensive treatment of the subject and the methodology involved. This book: Provides an overview of the hierarchy of study designs, and justifies the position of randomised trials at the top of this hierarchy. Discusses the strengths and defects of randomisation, and provides real evidence to justify concern regarding its defects. Outlays the damaging consequences that selection bias causes when it does occur. Considers courses of action that can be taken to manage/ contain the problem. Presents methods that can be used to detect selection bias in randomised trials, and methods to correct for selection bias. Concludes by providing a comprehensive plan for managing baseline imbalances and selection bias in randomised trials, and proposing open problems for future research. Illustrated with case studies, this book introduces groundbreaking ideas and research that will be invaluable to researchers and practitioners who design and analyse clinical trials. It will also be of interest to graduate students within the field of biostatistics.


Biased Trials

Biased Trials
Author: Goran Dominioni
Publisher: Springer Nature
Total Pages: 171
Release: 2020-05-01
Genre: Law
ISBN: 3658300809

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Goran Dominioni argues that research in behavioral economics, psychology, and neurosciences can offer novel insights on whether court decisions are accurate, non-discriminatory, and maximize social welfare. The author also shows that insights from these areas of research can help to improve trial outcomes if carefully applied to craft trial rules and practices. He covers central themes in behavioral law and economics, such as implicit racial biases, the fundamental attribution error, and gender-related biases.


Race and the Jury

Race and the Jury
Author: Hiroshi Fukurai
Publisher: Springer Science & Business Media
Total Pages: 270
Release: 2013-06-29
Genre: Psychology
ISBN: 1489911278

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In this timely volume, the authors provide a penetrating analysis of the institutional mechanisms perpetuating the related problems of minorities' disenfranchisement and their underrepresentation on juries.


Bias in Clinical Intervention Research

Bias in Clinical Intervention Research
Author: Lise Lotte Gluud
Publisher:
Total Pages: 32
Release: 2005
Genre: Clinical trials
ISBN: 9788799092406

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Big Data and Social Science

Big Data and Social Science
Author: Ian Foster
Publisher: CRC Press
Total Pages: 493
Release: 2016-08-10
Genre: Mathematics
ISBN: 1498751431

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Both Traditional Students and Working Professionals Acquire the Skills to Analyze Social Problems. Big Data and Social Science: A Practical Guide to Methods and Tools shows how to apply data science to real-world problems in both research and the practice. The book provides practical guidance on combining methods and tools from computer science, statistics, and social science. This concrete approach is illustrated throughout using an important national problem, the quantitative study of innovation. The text draws on the expertise of prominent leaders in statistics, the social sciences, data science, and computer science to teach students how to use modern social science research principles as well as the best analytical and computational tools. It uses a real-world challenge to introduce how these tools are used to identify and capture appropriate data, apply data science models and tools to that data, and recognize and respond to data errors and limitations. For more information, including sample chapters and news, please visit the author's website.


Randomized Controlled Trials

Randomized Controlled Trials
Author: Alehandro R. Jadad
Publisher: John Wiley & Sons
Total Pages: 170
Release: 2007-07-23
Genre: Medical
ISBN: 1405132663

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Randomized controlled trials are one of the most powerful and revolutionary tools of research. This book is a convenient and accessible description of the underlying principles and practice of randomized controlled trials and their role in clinical decision-making. Structured in a jargon-free question-and-answer format, each chapter provides concise and understandable information on a different aspect of randomized controlled trials, from the basics of trial design and terminology to the interpretation of results and their use in driving evidence-based medicine. The authors end each chapter with their musings, going beyond the evidence or citations, and sometimes even beyond orthodox correctness to share their thoughts and concerns about different aspects of randomized controlled trials, and their role within the health system. Updated to include insights from the last decade, this second edition challenges over-reliance on randomized controlled trials by debating their strengths and limitations and discussing their optimal use in modern healthcare. It also includes a new and increasingly relevant chapter on the ethics of randomized trials. World renowned writers and thinkers Drs Jadad and Enkin bring you this invaluable book for busy health professionals who wish to understand the theory of randomized controlled trials and their influence on clinical, research or policy decisions.


Proactive Policing

Proactive Policing
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
Total Pages: 409
Release: 2018-03-23
Genre: Law
ISBN: 0309467136

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Proactive policing, as a strategic approach used by police agencies to prevent crime, is a relatively new phenomenon in the United States. It developed from a crisis in confidence in policing that began to emerge in the 1960s because of social unrest, rising crime rates, and growing skepticism regarding the effectiveness of standard approaches to policing. In response, beginning in the 1980s and 1990s, innovative police practices and policies that took a more proactive approach began to develop. This report uses the term "proactive policing" to refer to all policing strategies that have as one of their goals the prevention or reduction of crime and disorder and that are not reactive in terms of focusing primarily on uncovering ongoing crime or on investigating or responding to crimes once they have occurred. Proactive policing is distinguished from the everyday decisions of police officers to be proactive in specific situations and instead refers to a strategic decision by police agencies to use proactive police responses in a programmatic way to reduce crime. Today, proactive policing strategies are used widely in the United States. They are not isolated programs used by a select group of agencies but rather a set of ideas that have spread across the landscape of policing. Proactive Policing reviews the evidence and discusses the data and methodological gaps on: (1) the effects of different forms of proactive policing on crime; (2) whether they are applied in a discriminatory manner; (3) whether they are being used in a legal fashion; and (4) community reaction. This report offers a comprehensive evaluation of proactive policing that includes not only its crime prevention impacts but also its broader implications for justice and U.S. communities.


Systematic Reviews in Health Care

Systematic Reviews in Health Care
Author: Matthias Egger
Publisher: John Wiley & Sons
Total Pages: 512
Release: 2008-04-15
Genre: Medical
ISBN: 0470693142

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The second edition of this best-selling book has been thoroughly revised and expanded to reflect the significant changes and advances made in systematic reviewing. New features include discussion on the rationale, meta-analyses of prognostic and diagnostic studies and software, and the use of systematic reviews in practice.