B Cell Receptor Signaling PDF Download
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| Author | : Tomohiro Kurosaki |
| Publisher | : Springer |
| Total Pages | : 231 |
| Release | : 2015-12-26 |
| Genre | : Medical |
| ISBN | : 3319261339 |
Download B Cell Receptor Signaling Book in PDF, ePub and Kindle
This volume details our current understanding of the architecture and signaling capabilities of the B cell antigen receptor (BCR) in health and disease. The first chapters review new insights into the assembly of BCR components and their organization on the cell surface. Subsequent contributions focus on the molecular interactions that connect the BCR with major intracellular signaling pathways such as Ca2+ mobilization, membrane phospholipid metabolism, nuclear translocation of NF-kB or the activation of Bruton’s Tyrosine Kinase and MAP kinases. These elements orchestrate cytoplasmic and nuclear responses as well as cytoskeleton dynamics for antigen internalization. Furthermore, a key mechanism of how B cells remember their cognate antigen is discussed in detail. Altogether, the discoveries presented provide a better understanding of B cell biology and help to explain some B cell-mediated pathogenicities, like autoimmune phenomena or the formation of B cell tumors, while also paving the way for eventually combating these diseases.
| Author | : Tasuku Honjo |
| Publisher | : Academic Press |
| Total Pages | : 0 |
| Release | : 2014-12-22 |
| Genre | : Science |
| ISBN | : 9780123979339 |
Download Molecular Biology of B Cells Book in PDF, ePub and Kindle
Molecular Biology of B Cells, Second Edition is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All of these developmental and stimulatory processes are described in molecular, immunological, and genetic terms to give a clear understanding of complex phenotypes. Molecular Biology of B Cells, Second Edition offers an integrated view of all aspects of B cells to produce a normal immune response as a constant, and the molecular basis of numerous diseases due to B cell abnormality. The new edition continues its success with updated research on microRNAs in B cell development and immunity, new developments in understanding lymphoma biology, and therapeutic targeting of B cells for clinical application. With updated research and continued comprehensive coverage of all aspects of B cell biology, Molecular Biology of B Cells, Second Edition is the definitive resource, vital for researchers across molecular biology, immunology and genetics.
| Author | : Ji-Yang Wang |
| Publisher | : Springer |
| Total Pages | : 181 |
| Release | : 2021-05-07 |
| Genre | : Medical |
| ISBN | : 9789811535345 |
Download B Cells in Immunity and Tolerance Book in PDF, ePub and Kindle
This book contains twelve chapters contributed by prestigious international experts who are at the forefront of B cell research, and aims to provide a cutting-edge and comprehensive overview of all aspects of B cells, including B cell development, maturation and activation, germinal center reaction, memory and plasma cell differentiation, and antibody-mediated positive and negative regulation of humoral immune responses. There are also three chapters describing human diseases caused by B cell abnormalities, including primary antibody deficiencies, autoimmune diseases, and B cell malignancies. We hope that this book will become a standard and routine reference for both basic researchers and clinicians.
| Author | : Chaohong Liu |
| Publisher | : |
| Total Pages | : 262 |
| Release | : 2018 |
| Genre | : B cells |
| ISBN | : 9781493974740 |
Download B Cell Receptor Signaling Book in PDF, ePub and Kindle
| Author | : Jonathan Soboloff |
| Publisher | : CRC Press |
| Total Pages | : 258 |
| Release | : 2017-03-27 |
| Genre | : Medical |
| ISBN | : 149870509X |
Download Signaling Mechanisms Regulating T Cell Diversity and Function Book in PDF, ePub and Kindle
T cells play a vital role mediating adaptive immunity, a specific acquired resistance to an infectious agent produced by the introduction of an antigen. There are a variety of T cell types with different functions. They are called T cells, because they are derived from the thymus gland. This volume discusses how T cells are regulated through the operation of signaling mechanisms. Topics covered include positive and negative selection, early events in T cell receptor engagement, and various T cell subsets.
| Author | : Wanli Liu |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2020 |
| Genre | : |
| ISBN | : |
Download BCR Signaling and B Cell Activation Book in PDF, ePub and Kindle
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
| Author | : Mourad Aribi |
| Publisher | : BoD – Books on Demand |
| Total Pages | : 163 |
| Release | : 2020-02-26 |
| Genre | : Medical |
| ISBN | : 178985430X |
Download Normal and Malignant B-Cell Book in PDF, ePub and Kindle
Normal and Malignant B-Cell is a collection of harmonious chapters contributed by different authors. This book sets out to describe the B-cell during different stages of ontogeny and the molecular mechanisms of its antigen receptor diversity. It also discusses the main clinical and etiopathogenic aspects when it is transformed into a malignant cell. The book will be interesting and useful for clinicians, biologists, researchers, teachers, and graduate students of both doctoral and master's degrees in the field of immunology.
| Author | : Hidde Ploegh |
| Publisher | : Academic Press |
| Total Pages | : 175 |
| Release | : 2014-05-16 |
| Genre | : Medical |
| ISBN | : 0128003634 |
Download Cell Biology of the B Cell Receptor Book in PDF, ePub and Kindle
Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future. Contributions from leading authorities Informs and updates on all the latest developments in the field
| Author | : Ayse Basak Engin |
| Publisher | : Springer Nature |
| Total Pages | : 415 |
| Release | : 2021-02-04 |
| Genre | : Medical |
| ISBN | : 3030498441 |
Download Protein Kinase-mediated Decisions Between Life and Death Book in PDF, ePub and Kindle
Protein phosphorylation via protein kinases is an inevitable process that alters physiological and pathological functions of the cells. Thus, protein kinases play key roles in the regulation of cell life or death decisions. Protein kinases are frequently a driving factor in a variety of human diseases including aging and cellular senescence, immune system and endothelial dysfunctions, cancers, insulin resistance, cholestasis and neurodegenerative diseases, as well as bacterial resistance in persistent infections. Recent developments in quantitative proteomics provide important opinions on kinase inhibitor selectivity and their modes of action in the biological context. Protein Kinase-mediated Decisions Between Life and Death aims to have the reader catch insights about up-to-date opinions on “Protein Kinases” related pathways that threaten human health and life. As “Protein Kinases” are related to many health problems, clinicians, basic science researchers and students need this information. Chapter “Signal Transduction in Immune Cells and Protein Kinases” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
| Author | : Wanli Liu |
| Publisher | : Frontiers Media SA |
| Total Pages | : 159 |
| Release | : 2020-02-24 |
| Genre | : |
| ISBN | : 2889635376 |
Download BCR Signaling and B Cell Activation Book in PDF, ePub and Kindle
