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Axially Chiral Compounds

Axially Chiral Compounds
Author: Bin Tan
Publisher: John Wiley & Sons
Total Pages: 338
Release: 2021-11-22
Genre: Science
ISBN: 3527347127

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Axially Chiral Compounds Explore this comprehensive and current volume summarizing the characteristics, synthesis, and applications of axial chirality Appearing widely in natural products, biologically active molecules, asymmetric chemistry, and material science, axially chiral motifs constitute the core backbones of the majority of chiral ligands and organocatalysts in asymmetric catalysis. In a new work of particular relevance to synthetic chemists, Axially Chiral Compounds: Asymmetric Synthesis and Applications delivers a clearly structured and authoritative volume covering the classification, characteristics, synthesis, and applications of axial chirality. A must read for every synthetic chemist practicing today, the book follows the development history, research status, and applications of axial chirality. An introductory chapter familiarizes the reader with foundational material before the distinguished authors describe the different classes and the synthesis of axial chiral compounds used in asymmetric synthesis. The book concludes with a focus on the applications of chiral ligands, chiral catalysts, and materials. Readers will also benefit from the inclusion of: A thorough introduction to asymmetric synthesis, including biaryls atropisomers, heterobiaryls atropisomers, and non-biaryls atropisomers Explorations of chiral allene, spiro skeletons, and natural products Practical discussions of asymmetric transformation, chiral ligands, and chiral catalysts An examination of miscellaneous applications of axially chiral compounds Perfect for organic chemists, chemists working with or on organometallics, catalytic chemists, and materials scientists, Axially Chiral Compounds: Asymmetric Synthesis and Applications will also earn a place in the libraries of natural products chemists who seek a one-stop reference for compounds exhibiting axial chirality.


Atropisomerism And Axial Chirality

Atropisomerism And Axial Chirality
Author: Lassaletta Jose M
Publisher: World Scientific
Total Pages: 676
Release: 2019-05-23
Genre: Science
ISBN: 1786346478

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Atropisomerism and Axial Chirality provides a global survey of the chemistry of axially chiral compounds including biaryls, heterobiaryls, non-biaryl atropisomers, allenes and spyrocyclic derivatives. From the perspective of a synthetic organic chemist, this book provides a unique compilation of the available methodologies for their synthesis, with emphasis on the most efficient and modern strategies, a review of the huge amount of practical applications in the field of asymmetric catalysis, either as transition metal ligands or as organocatalysts, and an overview of their occurrence as bioactive compounds and natural products.The first of its kind, this book serves as a general introduction and a practical reference to advanced chemistry students and researchers, while also offering creative ideas for further developments in the field.


Dynamic Stereochemistry of Chiral Compounds

Dynamic Stereochemistry of Chiral Compounds
Author: Christian Wolf
Publisher: Royal Society of Chemistry
Total Pages: 534
Release: 2008
Genre: Education
ISBN: 0854042466

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A comprehensive overview of fundamental concepts of asymmetric synthesis along with in-depth discussion. Recent developments that address important synthetic challenges are presented and highlighted with hundreds of examples.


Privileged Chiral Ligands and Catalysts

Privileged Chiral Ligands and Catalysts
Author: Qi-Lin Zhou
Publisher: John Wiley & Sons
Total Pages: 670
Release: 2011-02-10
Genre: Technology & Engineering
ISBN: 3527635211

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Catalytic asymmetric synthesis has been one of the most active research areas in chemistry (Nobel Prize in 2001). The development of efficient chiral catalysts plays a crucial role in asymmetric catalysis. Although many chiral ligands/catalysts have been developed in the past decades, the most efficient catalysts are derived from a few core structures, called "privileged chiral catalysts". This ultimate "must have" and long awaited reference for every chemist working in the field of asymmetric catalysis starts with the core structure of the catalysts, explaining why a certain ligand or catalyst is so successful. It describes in detail the history, the basic structural characteristics, and the applications of these "privileged catalysts". This novel presentation provides readers with a much deeper insight into the topic and makes it a must-have for organic chemists, catalytic chemists, chemists working with/on organometallics, chemists in industry, and libraries. From the contents: * BINAP * Bisphosphacycles - From DuPhos and BPE to a Diverse Set of Broadly Applied Ligands * Josiphos Ligands: From Discovery to Technical Applications * Chiral Spiro Ligands * Chiral Bisoxazoline Ligands * PHOX Ligands * Chiral Salen Complexes * BINOL * TADDOLate Ligands * Cinchona Alkaloids * Proline Derivatives


Rules for the Nomenclature of Organic Chemistry

Rules for the Nomenclature of Organic Chemistry
Author: L. C. Cross
Publisher: Elsevier
Total Pages: 21
Release: 2013-09-17
Genre: Science
ISBN: 1483284506

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Rules for the Nomenclature of Organic Chemistry: Section E: Stereochemistry (Recommendations 1974) deals with the main principles of stereochemistry. The rules discussed in this section have two main objects, namely, to prescribe, for basic views, terms that may provide a common language in all aspects of stereochemistry; and to define the ways in which these terms may be incorporated into the names of individual compounds. This book discusses the steric structure of a compound, which is denoted by an affix or affixes to the name that does not prescribe the stereochemistry. This text explains that isomers are termed stereoisomers when they differ only in the arrangement of the atoms in space. This book explains as well that the terms relative stereochemistry and relative configuration are used to describe the positions of substituents on different atoms in a molecule relative to one another. This book is a valuable resource for organic chemists.


Fundamentals of Asymmetric Catalysis

Fundamentals of Asymmetric Catalysis
Author: Patrick J. Walsh
Publisher: University Science Books
Total Pages: 692
Release: 2009-01-02
Genre: Science
ISBN: 9781891389542

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This work describes the essential aspects of enantioselective catalysis, with chapters organised by concept rather than by reaction type. Each concept is supported by examples to give the reader broad exposure to a wide range of catalysts, reactions and reaction mechanisms.


Iodine Catalysis in Organic Synthesis

Iodine Catalysis in Organic Synthesis
Author: Kazuaki Ishihara
Publisher: John Wiley & Sons
Total Pages: 452
Release: 2022-05-16
Genre: Technology & Engineering
ISBN: 3527348298

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Iodine Catalysis in Organic Synthesis The first book of its kind to highlight iodine as a sustainable alternative to conventional transition metal catalysis Iodine Catalysis in Organic Synthesis provides detailed coverage of recent advances in iodine chemistry and catalysis, focusing on the utilization of various iodine-containing compounds as oxidative catalysts. Featuring contributions by an international panel of leading research chemists, this authoritative volume explores the development of environmentally benign organic reactions and summarizes catalytic transformations of molecular iodine and iodine compounds such as hypervalent organoiodine and inorganic iodine salts. Readers are first introduced to the history of iodine chemistry, the conceptual background of homogeneous catalysis, and the benefits of iodine catalysis in comparison with transition metals. Next, chapters organized by reaction type examine enantioselective transformations, catalytic reactions involving iodine, catalyst states, oxidation in iodine and iodine catalyses, and catalytic reactions based on halogen bonding. Practical case studies and real-world examples of different applications in organic synthesis and industry are incorporated throughout the text. An invaluable guide for synthetic chemists in both academic and industrial laboratories, Iodine Catalysis in Organic Synthesis: Provides a thorough overview of typical iodine-catalyzed reactions, catalyst systems, structures, and reactivity Explores promising industrial applications of iodine-based reagents for organic synthesis Highlights the advantages iodine catalysis has over classical metal-catalyzed reactions Discusses sustainable and eco-friendly methods in hypervalent iodine chemistry Edited by two world authorities on the catalytic applications of organoiodine compounds, Iodine Catalysis in Organic Synthesis is required reading for catalytic, organic, and organometallic chemists, medicinal and pharmaceutical chemists, industrial chemists, and academic researchers and advanced students in relevant fields.


Circularly Polarized Luminescence of Isolated Small Organic Molecules

Circularly Polarized Luminescence of Isolated Small Organic Molecules
Author: Tadashi Mori
Publisher: Springer Nature
Total Pages: 342
Release: 2020-04-13
Genre: Science
ISBN: 9811523096

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This book collects all the latest advances in the leading research of the circularly polarized luminescence (CPL) of small organic molecules. Compared with that of lanthanide-based fluorophores, the research into the CPL of small organic molecules is still at the developmental stage for their relatively smaller dissymmetric factors, but has been a source of widespread attention recently. The book includes the state of the art of the discoveries in CPL organic molecules, such as helicenes, biaryls, cyclophanes, boron dipyrromethene dyes, and other chiral molecules, mostly in their isolated states, covering all possible chiral substances for future applications. This book also highlights the recent development of CPL instruments as well as time-resolved circular dichroism spectroscopy, to facilitate the further development and future design of CPL molecules.


Introduction to Stereochemistry

Introduction to Stereochemistry
Author: Andrew Clark
Publisher: Royal Society of Chemistry
Total Pages: 201
Release: 2020-10-23
Genre: Science
ISBN: 1788013158

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Stereochemistry is an important concept that often causes confusion amongst students when they learn it for the first time. In this book we deal with tricky concepts like conformation and configuration, how to represent them accurately and how to use the correct terms to describe them in both organic and inorganic chemistry.


Transition-Metal-Mediated Aromatic Ring Construction

Transition-Metal-Mediated Aromatic Ring Construction
Author: Ken Tanaka
Publisher: John Wiley & Sons
Total Pages: 785
Release: 2013-07-09
Genre: Science
ISBN: 111862999X

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State-of-the-science methods, synthetic routes, and strategies to construct aromatic rings The development of new reactions for the synthesis of aromatic compounds is a highly active research area in organic synthesis, providing new functional organic materials, functional reagents, and biologically active compounds. Recently, significant advances in transition-metal-mediated reactions have enabled the efficient and practical construction of new aromatic rings with useful properties and applications. This book draws together and reviews all the latest discoveries and methods in transition-metal-mediated reactions, offering readers promising new routes to design and construct complex aromatic compounds. Integrating metal catalysis with aromatic compound synthesis, Transition-Metal-Mediated Aromatic Ring Construction offers a practical guide to the methods, synthetic routes, and strategies for constructing aromatic compounds. The book's five parts examine: [2+2+2], [2+2+1], and related cycloaddition reactions [4+2], [3+2], and related cycloaddition reactions Electrocyclization reactions Coupling and addition reactions Other important transformations, including methathesis reactions and skeletal rearrangement reactions Edited by Ken Tanaka, an internationally recognized expert in the field of transition-metal catalysis, the book features authors who are leading pioneers and researchers in synthetic reactions. Their contributions reflect a thorough review and analysis of the literature as well as their own firsthand laboratory experience developing new aromatic compounds. All chapters end with a summary and outlook, setting forth new avenues of research and forecasting new discoveries. There are also references at the end of each chapter, guiding readers to important original research reports and reviews. In summary, Transition-Metal-Mediated Aromatic Ring Construction offers synthetic chemists a promising new avenue for the development of important new aromatic compounds with a broad range of applications.