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Fundamentals of Asymmetric Catalysis

Fundamentals of Asymmetric Catalysis
Author: Patrick J. Walsh
Publisher: University Science Books
Total Pages: 692
Release: 2009-01-02
Genre: Science
ISBN: 9781891389542

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This work describes the essential aspects of enantioselective catalysis, with chapters organised by concept rather than by reaction type. Each concept is supported by examples to give the reader broad exposure to a wide range of catalysts, reactions and reaction mechanisms.


Catalysis in Asymmetric Synthesis

Catalysis in Asymmetric Synthesis
Author: Vittorio Caprio
Publisher: John Wiley & Sons
Total Pages: 409
Release: 2009-03-09
Genre: Science
ISBN: 1405190914

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Asymmetric synthesis has become a major aspect of modern organic chemistry. The stereochemical properties of an organic compound are often essential to its bioactivity, and the need for stereochemically pure pharmaceutical products is a key example of the importance of stereochemical control in organic synthesis. However, achieving high levels of stereoselectivity in the synthesis of complex natural products represents a considerable intellectual and practical challenge for chemists. Written from a synthetic organic chemistry perspective, this text provides a practical overview of the field, illustrating a wide range of transformations that can be achieved. The book captures the latest advances in asymmetric catalysis with emphasis placed on non-enzymatic methods. Topics covered include: Reduction of alkenes, ketones and imines Nucleophilic addition to carbonyl compounds Catalytic carbon-carbon bond forming reactions Catalytic reactions involving metal carbenoids Conjugate addition reactions Catalysis in Asymmetric Synthesis bridges the gap between undergraduate and advanced level textbooks and provides a convenient point of entry to the primary literature for the experienced synthetic organic chemist.


Asymmetric Catalysis In Organic Synthesis

Asymmetric Catalysis In Organic Synthesis
Author: Ryoji Noyori
Publisher: Wiley-Interscience
Total Pages: 404
Release: 1994-02-03
Genre: Science
ISBN:

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Deals with basic principles of asymmetric catalysis focusing on its synthetic significance. Covers homogeneous asymmetric hydrogenation, asymmetric catalysis via chiral metal complexes, heterogeneous catalysis and non-organometallic catalysis. The collection of a range of stereoselective reactions illustrate various strategies and methodologies as well as their general utility.


Comprehensive Asymmetric Catalysis

Comprehensive Asymmetric Catalysis
Author: Eric N. Jacobsen
Publisher:
Total Pages: 520
Release: 1999
Genre: Asymmetric synthesis
ISBN:

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Accompanying CD-ROM contains the full-text search and a state-of-the-art graphic substructure search routine.


Organocatalysis

Organocatalysis
Author: Maurizio Benaglia
Publisher: Walter de Gruyter GmbH & Co KG
Total Pages: 606
Release: 2021-07-19
Genre: Science
ISBN: 3110588722

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Organocatalysis is considered today one of the three pillars in asymmetric catalysis, along with biocatalysis and organometallic catalysis. The current book gives an overview of the new reactions, the catalysts and their activation strategies reported in recent years. In addition, the applications of organocatalysis in total synthesis, radical reactions, flow chemistry and industrial practice are discussed.


New Frontiers in Asymmetric Catalysis

New Frontiers in Asymmetric Catalysis
Author: Koichi Mikami
Publisher: John Wiley & Sons
Total Pages: 436
Release: 2007-02-16
Genre: Science
ISBN: 047009799X

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A compilation of recent advances and applications in asymmetric catalysis The field of asymmetric catalysis has grown rapidly and plays a key role in drug discovery and pharmaceuticals. New Frontiers in Asymmetric Catalysis gives readers a fundamental understanding of the concepts and applications of asymmetric catalysis reactions and discusses the latest developments and findings. With contributions from preeminent scientists in their respective fields, it covers: * "Rational" ligand design, which is critically dependent on the reaction type (reduction, oxidation, and C-C bond formation) * Recent findings on activation of C-H bonds, C-C bonds, and small molecules (C=O, HCN, RN=C, and CO2) and the latest developments on C-C bond reorganization, such as metathesis * Advances in "chirally economical" non-linear phenomena, racemic catalysis, and autocatalysis * Some of the recent discoveries that have led to a renaissance in the field of organocatalysis, including the development of chiral Brönstead acids and Lewis acidic metals bearing the conjugate base of the Brönstead acids as the ligands and the chiral bi-functional acid/base catalysts The book ends with a thought-provoking perspective on the future of asymmetric catalysis that addresses both the challenges and the unlimited potential in this burgeoning field. This is an authoritative, up-to-date reference for organic chemists in academia, government, and industries, including pharmaceuticals, biotech, fine chemicals, polymers, and agriculture. It is also an excellent textbook for graduate students studying advanced organic chemistry or chemical synthesis.


Comprehensive Asymmetric Catalysis

Comprehensive Asymmetric Catalysis
Author: Eric N. Jacobsen
Publisher: Springer Science & Business Media
Total Pages: 258
Release: 2003-09-22
Genre: Science
ISBN: 9783540003335

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The first supplement to the three volume reference work "Comprehensive Asymmetric Catalysis" critically reviews new developments to the hottest topics in the field written by recognised experts. Eleven chapters which are already in the major reference work have been supplemented and additionally five new chapters have been included. Thus the state-of-the art in this area is now re-established. Together with the basic three volume book set this supplement is not only the principal reference source for synthetic organic chemists, but also for all scientific researchers who use chiral compounds in their work (for example, in biochemical investigations and molecular medicine) as well as for pharmaceutical chemists and other industrial researchers who prepare chiral compounds.


Catalytic Methods in Asymmetric Synthesis

Catalytic Methods in Asymmetric Synthesis
Author: Michelangelo Gruttadauria
Publisher: John Wiley & Sons
Total Pages: 721
Release: 2011-07-05
Genre: Science
ISBN: 1118087984

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This book covers advances in the methods of catalytic asymmetric synthesis and their applications. Coverage moves from new materials and technologies to homogeneous metal-free catalysts and homogeneous metal catalysts. The applications of several methodologies for the synthesis of biologically active molecules are discussed. Part I addresses recent advances in new materials and technologies such as supported catalysts, supports, self-supported catalysts, chiral ionic liquids, supercritical fluids, flow reactors and microwaves related to asymmetric catalysis. Part II covers advances and milestones in organocatalytic, enzymatic and metal-based mediated asymmetric synthesis, including applications for the synthesis of biologically active molecules. Written by leading international experts, this book consists of 16 chapters with 2000 References and illustrations of 560 schemes and figures.


Asymmetric Synthesis II

Asymmetric Synthesis II
Author: Mathias Christmann
Publisher: John Wiley & Sons
Total Pages: 406
Release: 2013-04-17
Genre: Science
ISBN: 3527672591

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After the overwhelming success of Asymmetric Synthesis - The Essentials, displaying a broad range of organic asymmetric syntheses, this is the second edition with latest subjects and authors. While the aim of the first edition was mainly to honor the achievements of the pioneers in asymmetric syntheses, the aim of this new edition was bringing the current developments, especially from younger colleagues, to the attention of students. The format of the book remained unchanged, i.e. short conceptual overviews by young leaders in their field including a short biography of the authors. The growing multidisciplinary research within chemistry is reflected in the selection of topics including metal catalysis, organocatalysis, physical organic chemistry, analytical chemistry, and its applications in total synthesis, materials research and industry. The prospective reader of this book is a graduate or undergraduate student of advanced organic chemistry as well as the industrial chemist who wants to get a brief update on the current developments in the field.


Asymmetric Organic Synthesis with Enzymes

Asymmetric Organic Synthesis with Enzymes
Author: Vicente Gotor
Publisher: John Wiley & Sons
Total Pages: 348
Release: 2008-03-31
Genre: Science
ISBN: 9783527318254

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Perfect for biochemists, synthetic and organic chemists, this book covers all important reactions, including C-C coupling reactions, oxidation reactions and many more. Divided into two parts, the first section on methodology presents new innovative methods for enzymatic catalysis optimization, including such new trends as medium engineering, directed evolution and computer-aided prediction of enantioselectivity. The second and main section deals with applications to synthesis, showing important reaction types and their applications. Only those reactions with very high selectivity are presented, allowing readers to improve their own reaction yields.