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ARF Family GTPases

ARF Family GTPases
Author: Richard A. Kahn
Publisher: Springer Science & Business Media
Total Pages: 368
Release: 2006-04-11
Genre: Science
ISBN: 1402025939

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For the first time experts in the area of signalling research with a focus on the ARF family have contributed to the production of a title devoted to ARF biology. A comprehensive phylogenetic analysis of the ARF family, tables of the ARF GEFs and ARF GAPs, and more than a dozen chapters describing them in detail are provided. The impact of the ARF proteins on widely diverse aspects of cell biology and cell signalling can be clearly seen from the activities described; including membrane traffic, lipid metabolism, receptor desensitization, mouse development, microtubule dynamics, and bacterial pathogenesis. Anyone interested in understanding the complexities of cell signalling and the integration of signalling networks will benefit from this volume.


Ras Superfamily Small G Proteins: Biology and Mechanisms 2

Ras Superfamily Small G Proteins: Biology and Mechanisms 2
Author: Alfred Wittinghofer
Publisher: Springer
Total Pages: 299
Release: 2014-09-26
Genre: Science
ISBN: 3319077619

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This second of two volumes discusses subfamily proteins which function in molecular and vesicular transport mechanisms inside the cell. In this volume the focus lies on the Rab, Ran and Arf subfamily members. As in Volume 1, the book is written by international renowned scientists in the field of small G-proteins. In elaborate reviews, biochemistry, structure, function and G-protein - effector interactions are described. Together with Volume 1 this book provides an comprehensive state-of-the-art work on small G-proteins (GTPases). It is written for Graduates and Professors in Biochemistry and Cell Biology interested in the mechanism and function of small G-proteins but are extremely valuable for those who want to move into the field.


Encyclopedia of Signaling Molecules

Encyclopedia of Signaling Molecules
Author: Sangdun Choi
Publisher: Springer
Total Pages: 6330
Release: 2017-12-15
Genre: Medical
ISBN: 9781493968008

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The second edition of this encyclopedia presents over 400 biologically important signaling molecules and the content is built on the core concepts of their functions along with early findings written by some of the world’s foremost experts. The molecules are described by recognized leaders in each molecule. The interactions of these single molecules in signal transduction networks will also be explored. This encyclopedia marks a new era in overview of current cellular signaling molecules for the specialist and the interested non-specialist alike. Currently, there are more than 30,000 genes in human genome. However, not all the proteins encoded by these genes work equally in order to maintain homeostasis. Understanding the important signaling molecules as completely as possible will significantly improve our research-based teaching and scientific capabilities.


G Protein Pathways, Part A: Receptors

G Protein Pathways, Part A: Receptors
Author:
Publisher: Academic Press
Total Pages: 719
Release: 2001-10-09
Genre: Science
ISBN: 0080884229

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G Protein Pathways is the first of three volumes examining the nature of heterotrimeric G proteins. The text takes an integrated approach to studying common experimental questions at many different levels related to G proteins. Methods related to G proteins using molecular modeling, systems biology, protein engineering, protein biochemistry, cell biology, and physiology are all accessible in the same volume. The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today truly an essential publication for researchers in all fields of life sciences.


Bacterial Virulence Factors and Rho GTPases

Bacterial Virulence Factors and Rho GTPases
Author: Patrice Boquet
Publisher: Springer Science & Business Media
Total Pages: 216
Release: 2005-04-01
Genre: Medical
ISBN: 9783540238652

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Pathogenic bacteria for human and animals have developed sophisticated weapons, termed virulence factors, to ensure their replication and persistence into their hosts. The authors in this volume show a synthesis on how the various host cellular Rho GTPases activities are manipulated by bacteria to fulfil their virulence.


Trafficking Inside Cells

Trafficking Inside Cells
Author: Nava Segev
Publisher: Springer Science & Business Media
Total Pages: 459
Release: 2010-05-30
Genre: Science
ISBN: 038793877X

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This book covers the past, present and future of the intra-cellular trafficking field, which has made a quantum leap in the last few decades. It details how the field has developed and evolved as well as examines future directions.


RAS Family GTPases

RAS Family GTPases
Author: Channing Der
Publisher: Springer
Total Pages: 0
Release: 2006-09-13
Genre: Medical
ISBN: 9781402043284

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Since 1982, Ras proteins have been the subject of intense research investigation by the biomedical research community. The wide interest in Ras has been stimulated for three key reasons. This book features chapters contributed by leading investigators in the field that highlight the current state-of-the art in Ras biochemistry, structure and biology. This book is an excellent reference for students in the biomedical sciences and for investigators in the field.


The Golgi Apparatus and the Plant Secretory Pathway

The Golgi Apparatus and the Plant Secretory Pathway
Author: David G. Robinson
Publisher: CRC Press
Total Pages: 280
Release: 2003
Genre: Medical
ISBN: 9780849328121

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The Golgi apparatus is a key component of plant and animal cells. Its primary role is to orchestrate the targeting of proteins and lipids to specific cellular destinations. With advances in our understanding of how the Golgi apparatus operates in plants, it will become possible to manipulate both the timing and the site of delivery of macromolecules, thus influencing plant growth and development. This volume concentrates on the major developments of the last few years, drawing attention to the distinct differences between the plant and non-plant Golgi apparatus and highlighting unsolved problems. A chapter is included on the yeast Golgi apparatus.


The Amphipathic Helix

The Amphipathic Helix
Author: Richard M. Epand
Publisher: CRC Press
Total Pages: 422
Release: 1993-07-09
Genre: Medical
ISBN: 9780849349263

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The Amphipathic Helix is a comprehensive volume discussing amphipathic helices in systems as diverse as serum lipoproteins, lung surfactant, cytotoxic peptides, ion channels, mitochondrial targeting, peptide hormones, G proteins, T-cell recognition, DNA binding proteins, and antifreeze proteins. The book also includes general introductory material that defines amphipathic helices, discusses methods to identify amphipathic helical segments from the amino acid sequence of a protein, illustrates how amphipathic helices can be used in the de novo design of peptide and protein structures, and describes how these helices stabilize protein structures. There is also a section on techniques to determine helix orientation in a membrane environment using polarized attenuated total reflection infrared spectroscopy or solid state NMR spectroscopy. Recent developments on all these topics have been discussed by leading experts in this reference for researchers and students in biochemistry, biophysics, and pharmacology.