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Molecular Protocols in Transfusion Medicine

Molecular Protocols in Transfusion Medicine
Author: Gregory A. Denomme
Publisher: Elsevier
Total Pages: 197
Release: 2000-04-27
Genre: Medical
ISBN: 0080536905

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This essential methods manual for immunohematologists (or hematologists and immunohematologists) provides information on genes that encode antigens on red blood cells, platelets and neutrophils. The book begins by covering general concepts in molecular biology and specific protocols such as DNA preparation, PCR-RFLP and allele-specific PCR. Information on the erythrocyte, platelet and neutrophil antigen systems and the molecular basis of polymorphisms are presented clearly in a gene facts sheet format. Database accession numbers and useful adjuncts such as Request forms, worksheets for PCR/enzyme digests also serve to benefit the user. The information is clearly presented and easily accessible and is complemented by the excellent diagrams and tabular material. This book is invaluable for both new and experienced researchers in the field and other related disciplines. Essential for hematologists and those involoved in tissue typing and the study of human genetic polymorphisms Presents clearly and concisely the information on a particular variant and the technique used to detect it Organized by antigen and provides sequences of polymorphisms and primers Details the general concepts and critical information on genes, their products, and sources of relevant nucleic acids Includes protocols that allow investigators to set up assays with minimal effort (protocols include primers, reagents, reaction conditions, sizes of amplified products, restriction fragment digests, and the relevant safety information) Provides information that helps interpret results in clinical settings Contains additional sources of information (e.g., key references, web site addresses, glossary, Database accession numbers, request forms, and worksheets for PCR/enzyme digests)


Molecular Biology in Blood Transfusion

Molecular Biology in Blood Transfusion
Author: Cees Smit Sibinga
Publisher: Springer Science & Business Media
Total Pages: 304
Release: 2000-09-30
Genre: Medical
ISBN: 9780792365341

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The international symposia on blood transfusion in Groningen have taken place without interruption since 1976. Each year Dr. Smit-Sibinga and his team have not only organized a meeting on timely topics in blood transfusion, but also succeeded in attracting prominent chairmen and speakers. The subject of the 24th Symposium was Molecular Biology in Blood Transfusion and it was chaired by Dr. Harvey G. Klein, National Institutes of Health, USA. In this book of proceedings an extraordinary range of subjects is covered, including diagnostic aspects, virology, quality control, cell and protein processing as well as a section on new horizons in clinical medicine.


Blood Banking and Transfusion Medicine

Blood Banking and Transfusion Medicine
Author: Christopher D. Hillyer
Publisher: Elsevier Health Sciences
Total Pages: 910
Release: 2006-10-18
Genre: Medical
ISBN: 0443069816

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Ever since the discovery of blood types early in the last century, transfusion medicine has evolved at a breakneck pace. This second edition of Blood Banking and Transfusion Medicine is exactly what you need to keep up. It combines scientific foundations with today's most practical approaches to the specialty. From blood collection and storage to testing and transfusing blood components, and finally cellular engineering, you'll find coverage here that's second to none. New advances in molecular genetics and the scientific mechanisms underlying the field are also covered, with an emphasis on the clinical implications for treatment. Whether you're new to the field or an old pro, this book belongs in your reference library. Integrates scientific foundations with clinical relevance to more clearly explain the science and its application to clinical practice. Highlights advances in the use of blood products and new methods of disease treatment while providing the most up-to-date information on these fast-moving topics Discusses current clinical controversies, providing an arena for the discussion of sensitive topics. Covers the constantly changing approaches to stem cell transplantation and brings you the latest information on this controversial topic.


BeadChip Molecular Immunohematology

BeadChip Molecular Immunohematology
Author: JoAnn M. Moulds
Publisher: Springer Science & Business Media
Total Pages: 170
Release: 2010-11-25
Genre: Medical
ISBN: 1441975128

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This text is a review of molecular immunohematology (MI). It draws from analyses and case studies around the world and details many techniques used in many labs. It is aimed at anyone interested in how MI is changing blood bank and transfusion medicine.


Introduction to Molecular Immunohematology

Introduction to Molecular Immunohematology
Author: Tony S. Casina
Publisher:
Total Pages:
Release: 2020
Genre:
ISBN: 9781563953668

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"The book will be an approachable guide to learning about molecular testing as it relates to blood banking and Immunohematology. Methods will be discussed, allele tables explained, and nuances taught, so that the reader will feel comfortable understanding and using the resources that are available. It will be a useful tool to the SBB student or pathology resident studying for exams"--Provided by publisher.


Biotechnology in blood transfusion

Biotechnology in blood transfusion
Author: Cees Smit Sibinga
Publisher: Springer
Total Pages: 258
Release: 2011-10-06
Genre: Medical
ISBN: 9781461289883

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This symposium is devoted to Biotechnology in Blood Transfusion; there are 22 experts discussing the state of the art in the application of monoclonal anti bodies, recombinant DNA technologies and heterologous expression systems to the improvement and sometimes replacement of blood products, charac terization of blood constituents, and the effect of these developments on blood transfusion procedures. Ten and maybe five years ago the title of a symposium such as this would have been Biosciences in blood transfusion, informing what basic developments in molecular biology, biochemistry and human physiology might pertain to blood transfusion in the distant future. That future is getting closer, and not only one is interested in basic developments in immunology, recognition and identification of viral and bacterial components and products, tissue and blood bloodgroup blood group typing, typing, but also in the potential application of these developments and their economic perspectives. That is what biotechnology is all alI about: basic science telIs tells us where and how we might look for new technologies, and the development of such tech nologies is only possible if there is a perspective for improvement in quality, safety, acceptance or performance to cost ratio.


Textbook of Blood Banking and Transfusion Medicine

Textbook of Blood Banking and Transfusion Medicine
Author: Sally V. Rudmann
Publisher: Elsevier Health Sciences
Total Pages: 704
Release: 2005-02-18
Genre: Medical
ISBN: 072160384X

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This comprehensive book on transfusion practices and immunohematology offers concise, thorough guidelines on the best ways to screen donors, store blood components, ensure safety, anticipate the potentially adverse affects of blood transfusion, and more. It begins with the basics of genetics and immunology, and then progresses to the technical aspects of blood banking and transfusion. Chapters are divided into sections on: Basic Science Review; Blood Group Serology; Donation, Preparation, and Storage; Pretransfusion Testing; Transfusion Therapy; Clinical Considerations; and Safety, Quality Assurance, and Data Management. Developed specifically for medical technologists, blood bank specialists, and residents, the new edition conforms to the most current standards of the American Association of Blood Banks (AABB). Expert Opinion essays, written by well-known, frequently published experts, discuss interesting topics of research or new advances in the field. Important terms are defined in the margins of the pages on which they appear, enabling readers to easily check the meaning of an unfamiliar term where it appears in context. Margin notes highlight important concepts and points, remind readers of previously discussed topics, offer an alternative perspective, or refer readers to other sources for further information. Material conforms to the most recent AABB standards for the most accurate, up-to-date information on immunohematology. Advanced concepts, beyond what is required for entry-level practice, are set apart from the rest of the text so readers can easily differentiate between basic and advanced information. A new chapter on Hematopoietic Stem Cells and Cellular Therapy (chapter 19) provides cutting-edge coverage of cellular therapy and its relevance to blood-banking. New content has been added on molecular genetics, component therapy, and International Society of Blood Transfusion (ISBT) nomenclature, as well as the latest information on HIV, hepatitis, quality assurance, and information systems. Coverage of new technologies, such as nucleic acid technology and gel technology, keeps readers current with advances in the field.


Molecular Medicine for Clinicians

Molecular Medicine for Clinicians
Author: Barry Mendelow
Publisher: Wits University Press
Total Pages: 526
Release: 2008-01-01
Genre: Science
ISBN: 1868144658

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The insights following the wake of the Human Genome project are radically influencing our understanding of the molecular basis of life, health and disease. The improved accuracy and precision of clinical diagnostics is also beginning to have an impact on therapeutics in a fundamental way. This book is suitable for undergraduate medical students, as part of their basic sciences training, but is also relevant to interested under- and postgraduate science and engineering students. It serves as an introductory text for medical registrars in virtually all specialties, and is also of value to the General Practitioner wishing to keep up to date, especially in view of the growing, internet-assisted public knowledge of the field. There is a special focus on the application of molecular medicine in Africa and in developing countries elsewhere.