Applications Of Heterocycles In The Design Of Drugs And Agricultural Products PDF Download
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| Author | : |
| Publisher | : Academic Press |
| Total Pages | : 332 |
| Release | : 2021-06-09 |
| Genre | : Science |
| ISBN | : 0128201827 |
Download Applications of Heterocycles in the Design of Drugs and Agricultural Products Book in PDF, ePub and Kindle
Applications of Heterocycles in the Design of Drugs and Agricultural Products, Volume 134 in the Advances in Heterocyclic Chemistry series represents the most definitive series in the field - one of great importance to organic chemists, polymer chemists, and many biological scientists. Chapters in this updated volume cover Hydroxy azoles as carboxylic acid bioisosteres, Cyclic sulfoxides and sulfones in drug design, Thiazoles and topological control in drug design, Applications of fused pyrrolidine [3.3.0] heterocycles in drug design, 1,4 Disubstituted and 1,4,5 trisubstituted-1,2,3-triazoles in drug discovery and development: from the flask to the clinic, and Conformationally restricted [3.2.2]- and [3.2.1]-3-azabicyclic diamines. Because biology and organic chemistry increasingly intersect, the associated nomenclature is being used more frequently in explanations. Written by established authorities in the field from around the world, this comprehensive review combines descriptive synthetic chemistry and mechanistic insight to yield an understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds. Considered the definitive serial in the field of heterocyclic chemistry Serves as the go-to reference for organic chemists, polymer chemists and biological scientists Provides the latest, comprehensive reviews written by established authorities in the field Combines descriptive synthetic chemistry and mechanistic insight to enhance understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds
| Author | : Navjeet Kaur |
| Publisher | : Elsevier |
| Total Pages | : 526 |
| Release | : 2020-04-25 |
| Genre | : Science |
| ISBN | : 0128202831 |
Download Metal and Nonmetal Assisted Synthesis of Six-Membered Heterocycles Book in PDF, ePub and Kindle
Metal and Nonmetal Assisted Synthesis of Six-Membered Heterocycles provides a useful guide to key approaches being explored in this area. The volume highlights synthetic approaches and catalytic options that facilitate the construction of multiple substituted molecules under mild conditions from easily available starting substrates. Drawing on the experience of its expert author, the book is a useful guide on the key approaches being explored in this area. Following a user-friendly structure based on specific six-membered heterocycle ring groups, this volume highlights synthetic approaches and catalytic options that facilitate the construction of multiple substituted molecules under mild conditions from easily available starting substrates. Highlights new methodologies for the synthesis of different six-membered heterocycles Provides an up-to-date overview of this fast-moving field with an easy-to-use structure Includes novel approaches used in the study and application of catalysts in synthetic organic reactions
| Author | : Goutam Brahmachari |
| Publisher | : Elsevier |
| Total Pages | : 642 |
| Release | : 2021-02-26 |
| Genre | : Science |
| ISBN | : 0128205865 |
Download Green Synthetic Approaches for Biologically Relevant Heterocycles Book in PDF, ePub and Kindle
Green Synthetic Approaches for Biologically Relevant Heterocycles, Second Edition, Volume One: Advanced Synthetic Techniques reviews this significant group of organic compounds within the context of sustainable methods and processes, expanding on the first edition with fully updated coverage and a whole range of new chapters. Volume One explores advanced synthetic techniques, with each chapter presenting in-depth coverage of various green protocols for the synthesis of a wide variety of bioactive heterocycles that are classified on the basis of ring-size and/or the presence of heteroatoms. Techniques covered range from high pressure cycloaddition reactions and microwave irradiation to sustainable one-pot domino reactions. This updated edition is an essential resource on sustainable approaches for academic researchers, R&D professionals, and students working across medicinal, organic, natural product and green chemistry. Provides fully updated coverage of the field of greener heterocycle synthesis Includes new chapters on varied multicomponent reactions, alongside both traditional and novel approaches Presents information in an accessible style with an emphasis on sustainability
| Author | : Clemens Lamberth |
| Publisher | : John Wiley & Sons |
| Total Pages | : 367 |
| Release | : 2012-08-16 |
| Genre | : Science |
| ISBN | : 3527664475 |
Download Bioactive Heterocyclic Compound Classes Book in PDF, ePub and Kindle
The chemistry of heterocycles is an important branch of organic chemistry. This is due to the fact that a large number of natural products, e. g. hormones, antibiotics, vitamins, etc. are composed of heterocyclic structures. Often, these compounds show beneficial properties and are therefore applied as pharmaceuticals to treat diseases or as insecticides, herbicides or fungicides in crop protection. This volume presents important pharmaceuticals. Each of the 20 chapters covers in a concise manner one class of heterocycles, clearly structuredas follows: * Structural formulas of most important examples (market products) * Short background of history or discovery * Typical syntheses of important examples * Mode of action * Characteristic biological activity * Structure-activity relationship * Additional chemistry information (e.g. further transformations, alternative syntheses, metabolic pathways, etc.) * References. A valuable one-stop reference source for researchers in academia and industry as well as for graduate students with career aspirations in the pharmaceutical chemistry.
| Author | : Jonathan L. Sessler |
| Publisher | : |
| Total Pages | : 480 |
| Release | : 2005 |
| Genre | : Medical |
| ISBN | : |
Download Medicinal Inorganic Chemistry Book in PDF, ePub and Kindle
This book reviews the current diagnostic and therapeutic uses of metal-containing compounds in medicine, as well as the role of metals in disease.
| Author | : Mousumi Sen |
| Publisher | : John Wiley & Sons |
| Total Pages | : 564 |
| Release | : 2024-10-01 |
| Genre | : Science |
| ISBN | : 1394212550 |
Download Sustainable Green Catalytic Processes Book in PDF, ePub and Kindle
Did you know that 95% of chemicals in industry are synthesized using catalysts? Sustainable Green Catalytic Processes offer concise descriptions of the application of catalysts in orchestrating eco-friendly transformation. These catalysts have enhanced selectivity for desired products while minimizing the creation of unwanted products. The book aims to present a collection of chapters related to green synthesis and methodologies and their applications in catalysis. These approaches have garnered attention from scientists in developing sustainable catalyst protocols that are environmentally greener and eco-friendly. This book aims to present a collection of chapters related to green synthesis and methodologies to motivate biochemists and engineers to provide a more sustainable environmental process. The first chapter focuses on the creation of ecologically friendly chemical processes. Another chapter frames the recent advances in heterogeneous photocatalysis and its applications. The book gives insights into the mechanisms underlying the total synthesis and functionalization of natural products through light-driven reactions. It reflects the new challenges as the chemical industry transitions to environmentally friendly and sustainable chemistry.
| Author | : Montserrat Diéguez |
| Publisher | : John Wiley & Sons |
| Total Pages | : 431 |
| Release | : 2018-02-21 |
| Genre | : Technology & Engineering |
| ISBN | : 3527804072 |
Download Artificial Metalloenzymes and MetalloDNAzymes in Catalysis Book in PDF, ePub and Kindle
An important reference for researchers in the field of metal-enzyme hybrid catalysis Artificial Metalloenzymes and MetalloDNAzymes in Catalysis offers a comprehensive review of the most current strategies, developed over recent decades, for the design, synthesis, and optimization of these hybrid catalysts as well as material about their application. The contributors—noted experts in the field—present information on the preparation, characterization, and optimization of artificial metalloenzymes in a timely and authoritative manner. The authors present a thorough examination of this interesting new platform for catalysis that combines the excellent selective recognition/binding properties of enzymes with transition metal catalysts. The text includes information on the various applications of metal-enzyme hybrid catalysts for novel reactions, offers insights into the latest advances in the field, and contains an informative perspective on the future: Explores the development of artificial metalloenzymes, the modern and strongly evolving research field on the verge of industrial application Contains a comprehensive reference to the research area of metal-enzyme hybrid catalysis that has experienced tremendous growth in recent years Includes contributions from leading researchers in the field Shows how this new catalysis combines the selective recognition/binding properties of enzymes with transition metal catalysts Written for catalytic chemists, bioinorganic chemists, biochemists, and organic chemists, Artificial Metalloenzymes and MetalloDNAzymes in Catalysis offers a unique reference to the fundamentals, concepts, applications, and the most recent developments for more efficient and sustainable synthesis.
| Author | : Oleg V. Larionov |
| Publisher | : Springer |
| Total Pages | : 163 |
| Release | : 2017-07-12 |
| Genre | : Science |
| ISBN | : 3319606875 |
Download Heterocyclic N-Oxides Book in PDF, ePub and Kindle
The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field. All chapters from Topics in Heterocyclic Chemistry are published Online First with an individual DOI. In references, Topics in Heterocyclic Chemistry is abbreviated as Top Heterocycl Chem and cited as a journal.
| Author | : Nathan Brown |
| Publisher | : John Wiley & Sons |
| Total Pages | : 249 |
| Release | : 2012-06-18 |
| Genre | : Medical |
| ISBN | : 3527654321 |
Download Bioisosteres in Medicinal Chemistry Book in PDF, ePub and Kindle
Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism. As such, it provides a ready reference on the principles and methods of bioisosteric replacement as a key tool in preclinical drug development. The first part provides an overview of bioisosterism, classical bioisosteres and typical molecular interactions that need to be considered, while the second part describes a number of molecular databases as sources of bioisosteric identification and rationalization. The third part covers the four key methodologies for bioisostere identification and replacement: physicochemical properties, topology, shape, and overlays of protein-ligand crystal structures. In the final part, several real-world examples of bioisosterism in drug discovery projects are discussed. With its detailed descriptions of databases, methods and real-life case studies, this is tailor-made for busy industrial researchers with little time for reading, while remaining easily accessible to novice drug developers due to its systematic structure and introductory section.
| Author | : Serban C. Moldoveanu |
| Publisher | : Elsevier |
| Total Pages | : 737 |
| Release | : 2009-09-16 |
| Genre | : Science |
| ISBN | : 0080932150 |
Download Pyrolysis of Organic Molecules Book in PDF, ePub and Kindle
Pyrolysis of Organic Molecules with Applications to Health and Environmental Issues, the 28th volume in the Techniques and Instrumentation in Analytical Chemistry series, gives a systematic and comprehensive description of pyrolysis of non-polymeric organic molecules. Pyrolysis is involved in many practical applications as well as in many common human activities, but harmful compounds can be generated in the process. The study of pyrolysis and of the formation of undesirable compounds as a result of pyrolytic processes is of considerable interest to chemists, chemical engineers, and toxicologists. Pyrolysis results for compounds not previously studied or reported Updated information from a large body of results published on pyrolysis of individual compounds or classes of compounds Information on mechanisms and kinetics of numerous pyrolytic processes
