Animal Models In Medicine And Biology PDF Download
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Author | : P. Michael Conn |
Publisher | : Academic Press |
Total Pages | : 1109 |
Release | : 2013-05-29 |
Genre | : Science |
ISBN | : 0124159125 |
Download Animal Models for the Study of Human Disease Book in PDF, ePub and Kindle
Animal Models for the Study of Human Disease identifies important animal models and assesses the advantages and disadvantages of each model for the study of human disease. The first section addresses how to locate resources, animal alternatives, animal ethics and related issues, much needed information for researchers across the biological sciences and biomedicine.The next sections of the work offers models for disease-oriented topics, including cardiac and pulmonary diseases, aging, infectious diseases, obesity, diabetes, neurological diseases, joint diseases, visual disorders, cancer, hypertension, genetic diseases, and diseases of abuse. Organized by disease orientation for ease of searchability Provides information on locating resources, animal alternatives and animal ethics Covers a broad range of animal models used in research for human disease
Author | : Eva Tvrdá |
Publisher | : BoD – Books on Demand |
Total Pages | : 248 |
Release | : 2020-04-08 |
Genre | : Science |
ISBN | : 1838800115 |
Download Animal Models in Medicine and Biology Book in PDF, ePub and Kindle
Thanks to animal models, our knowledge of biology and medicine has increased enormously over the past decades, leading to significant breakthroughs that have had a direct impact on the prevention, management and treatment of a wide array of diseases.This book presents a comprehensive reference that reflects the latest scientific research being done in a variety of medical and biological fields utilizing animal models. Chapters on Drosophila, rat, pig, rabbit, and other animal models reflect frontier research in neurology, psychiatry, cardiology, musculoskeletal disorders, reproduction, chronic diseases, epidemiology, and pain and inflammation management. Animal Models in Medicine and Biology offers scientists, clinicians, researchers and students invaluable insights into a wide range of issues at the forefront of medical and biological progress.
Author | : P. Michael Conn |
Publisher | : Springer Science & Business Media |
Total Pages | : 756 |
Release | : 2008 |
Genre | : Medical |
ISBN | : 1588299333 |
Download Sourcebook of Models for Biomedical Research Book in PDF, ePub and Kindle
The collection of systems represented in Sourcebook of genomic programs, although this work is certainly well Models for Biomedical Research is an effort to re?ect the represented and indexed. diversity and utility of models that are used in biomedicine. Some models have been omitted due to page limitations That utility is based on the consideration that observations and we have encouraged the authors to use tables and made in particular organisms will provide insight into the ? gures to make comparisons of models so that observations workings of other, more complex, systems. Even the cell not available in primary publications can become useful to cycle in the simple yeast cell has similarities to that in the reader. humans and regulation with similar proteins occurs. We thank Richard Lansing and the staff at Humana for Some models have the advantage that the reproductive, guidance through the publication process. mitotic, development or aging cycles are rapid compared As this book was entering production, we learned of the with those in humans; others are utilized because individual loss of Tom Lanigan, Sr. Tom was a leader and innovator proteins may be studied in an advantageous way and that in scienti?c publishing and a good friend and colleague to have human homologs. Other organisms are facile to grow all in the exploratory enterprise. We dedicate this book to in laboratory settings or lend themselves to convenient analy- his memory. We will miss him greatly.
Author | : National Research Council |
Publisher | : National Academies Press |
Total Pages | : 113 |
Release | : 1988-02-01 |
Genre | : Science |
ISBN | : 0309038391 |
Download Use of Laboratory Animals in Biomedical and Behavioral Research Book in PDF, ePub and Kindle
Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.
Author | : Michael Alan Singer |
Publisher | : World Scientific |
Total Pages | : 290 |
Release | : 2007-07-27 |
Genre | : Science |
ISBN | : 1908979305 |
Download Comparative Physiology, Natural Animal Models And Clinical Medicine: Insights Into Clinical Medicine From Animal Adaptations Book in PDF, ePub and Kindle
This book describes a novel and unique approach to the treatment of human diseases based on the study of natural animal models. A natural animal model is defined as an animal group or species that possesses a set of biochemical/physiological characteristics which are natural and adaptive for that animal, but are quite abnormal for humans. For example, how is it that birds can tolerate blood glucose concentrations which in humans are associated with diabetes. The natural animal model is living proof that a biological answer to this question is available. By studying natural animal models, we can gain valuable insights into the treatment of various human clinical disorders. Covering a wide range of disorders, this book describes in detail how medical scientists can take advantage of all the “research” that nature has already performed over billions of years in biological problem solving through extensive animal design testing and selection./a
Author | : National Academies of Sciences, Engineering, and Medicine |
Publisher | : National Academies Press |
Total Pages | : 139 |
Release | : 2018-06-29 |
Genre | : Science |
ISBN | : 0309471168 |
Download Advancing Disease Modeling in Animal-Based Research in Support of Precision Medicine Book in PDF, ePub and Kindle
Precision medicine is focused on the individual and will require the rapid and accurate identification and prioritization of causative factors of disease. To move forward and accelerate the delivery of the anticipated benefits of precision medicine, developing predictable, reproducible, and reliable animal models will be essential. In order to explore the topic of animal-based research and its relevance to precision medicine, the National Academies of Sciences, Engineering, and Medicine convened a 2-day workshop on October 5 and 6, 2017. The workshop was designed to focus on the development, implementation, and interpretation of model organisms to advance and accelerate the field of precision medicine. Participants examined the extent to which next-generation animal models, designed using patient data and phenotyping platforms targeted to reveal and inform disease mechanisms, will be essential to the successful implementation of precision medicine. This publication summarizes the presentations and discussions from the workshop.
Author | : Cynthia Petrie Smith |
Publisher | : |
Total Pages | : 66 |
Release | : 1991 |
Genre | : Animal models in research |
ISBN | : |
Download Animal Models in Biomedical Research Book in PDF, ePub and Kindle
Author | : Bartholomew Ibeh |
Publisher | : BoD – Books on Demand |
Total Pages | : 410 |
Release | : 2018-05-23 |
Genre | : Science |
ISBN | : 1789231647 |
Download Experimental Animal Models of Human Diseases Book in PDF, ePub and Kindle
The world has recorded losses in terms of human life as well as extensive time spent in experimentation with development of new drugs, elucidation of disease mechanism(s), and therapeutic agent discovery. Ethical and legal issues cojoin in slowing down scientific discoveries in medicine and biology. The past two (2) decades, therefore, have seen tremendous attempts that largely are successful in developing animal models with the characteristics of mimicking, approximating, or expressing transplanted human organs/tissues. These models or rather approaches seem to be fast, cost-effective, and easy to maintain compared to primates. This book is a collection of expert essays on animal models of human diseases of global interest. A visible objective of the book is to provide real-time experimental approach to scientists, clinicians, ethicists, medicolegal/medical jurisprudence workers, immunologists, postgraduate students, and vaccinologists and informative and multidisciplinary approach for the identification of new therapeutic targets and biomarkers using animal models as well as investigating the pathogenesis and therapeutic strategies of human diseases. An increased understanding of the genetic, molecular, and cellular mechanisms responsible for the development of human diseases has laid out the foundation for the development of rational therapies mainly with animal models.
Author | : National Academies of Sciences, Engineering, and Medicine |
Publisher | : National Academies Press |
Total Pages | : 115 |
Release | : 2018-05-23 |
Genre | : Science |
ISBN | : 0309463882 |
Download Animal Models for Microbiome Research Book in PDF, ePub and Kindle
The surface of the human body and its mucous membranes are heavily colonized by microorganisms. Our understanding of the contributions that complex microbial communities make to health and disease is advancing rapidly. Most microbiome research to date has focused on the mouse as a model organism for delineating the mechanisms that shape the assembly and dynamic operations of microbial communities. However, the mouse is not a perfect surrogate for studying different aspects of the microbiome and how it responds to various environmental and host stimuli, and as a result, researchers have been conducting microbiome studies in other animals. To examine the different animal models researchers employ in microbiome studies and to better understand the strengths and weaknesses of each of these model organisms as they relate to human and nonhuman health and disease, the Roundtable on Science and Welfare in Laboratory Animal Use of the National Academies of Sciences, Engineering, and Medicine convened a workshop in December 2016. The workshop participants explored how to improve the depth and breadth of analysis of microbial communities using various model organisms, the challenges of standardization and biological variability that are inherent in gnotobiotic animal-based research, the predictability and translatability of preclinical studies to humans, and strategies for expanding the infrastructure and tools for conducting studies in these types of models. This publication summarizes the presentations and discussions from the workshop.
Author | : National Research Council |
Publisher | : National Academies Press |
Total Pages | : 85 |
Release | : 1998-02-16 |
Genre | : Science |
ISBN | : 0309060354 |
Download Biomedical Models and Resources Book in PDF, ePub and Kindle
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