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Analysis of Repeated Measures Data

Analysis of Repeated Measures Data
Author: M. Ataharul Islam
Publisher: Springer
Total Pages: 257
Release: 2017-07-06
Genre: Business & Economics
ISBN: 9811037949

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This book presents a broad range of statistical techniques to address emerging needs in the field of repeated measures. It also provides a comprehensive overview of extensions of generalized linear models for the bivariate exponential family of distributions, which represent a new development in analysing repeated measures data. The demand for statistical models for correlated outcomes has grown rapidly recently, mainly due to presence of two types of underlying associations: associations between outcomes, and associations between explanatory variables and outcomes. The book systematically addresses key problems arising in the modelling of repeated measures data, bearing in mind those factors that play a major role in estimating the underlying relationships between covariates and outcome variables for correlated outcome data. In addition, it presents new approaches to addressing current challenges in the field of repeated measures and models based on conditional and joint probabilities. Markov models of first and higher orders are used for conditional models in addition to conditional probabilities as a function of covariates. Similarly, joint models are developed using both marginal-conditional probabilities as well as joint probabilities as a function of covariates. In addition to generalized linear models for bivariate outcomes, it highlights extended semi-parametric models for continuous failure time data and their applications in order to include models for a broader range of outcome variables that researchers encounter in various fields. The book further discusses the problem of analysing repeated measures data for failure time in the competing risk framework, which is now taking on an increasingly important role in the field of survival analysis, reliability and actuarial science. Details on how to perform the analyses are included in each chapter and supplemented with newly developed R packages and functions along with SAS codes and macro/IML. It is a valuable resource for researchers, graduate students and other users of statistical techniques for analysing repeated measures data.


Statistical Methods for the Analysis of Repeated Measurements

Statistical Methods for the Analysis of Repeated Measurements
Author: Charles S. Davis
Publisher: Springer Science & Business Media
Total Pages: 416
Release: 2008-01-10
Genre: Mathematics
ISBN: 0387215735

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A comprehensive introduction to a wide variety of statistical methods for the analysis of repeated measurements. It is designed to be both a useful reference for practitioners and a textbook for a graduate-level course focused on methods for the analysis of repeated measurements. The important features of this book include a comprehensive coverage of classical and recent methods for continuous and categorical outcome variables; numerous homework problems at the end of each chapter; and the extensive use of real data sets in examples and homework problems.


Longitudinal Data Analysis

Longitudinal Data Analysis
Author: Garrett Fitzmaurice
Publisher: CRC Press
Total Pages: 633
Release: 2008-08-11
Genre: Mathematics
ISBN: 142001157X

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Although many books currently available describe statistical models and methods for analyzing longitudinal data, they do not highlight connections between various research threads in the statistical literature. Responding to this void, Longitudinal Data Analysis provides a clear, comprehensive, and unified overview of state-of-the-art theory


Analysis of Repeated Measures

Analysis of Repeated Measures
Author: Martin J. Crowder
Publisher: Routledge
Total Pages: 190
Release: 2017-10-24
Genre: Mathematics
ISBN: 1351466631

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Repeated measures data arise when the same characteristic is measured on each case or subject at several times or under several conditions. There is a multitude of techniques available for analysing such data and in the past this has led to some confusion. This book describes the whole spectrum of approaches, beginning with very simple and crude methods, working through intermediate techniques commonly used by consultant statisticians, and concluding with more recent and advanced methods. Those covered include multiple testing, response feature analysis, univariate analysis of variance approaches, multivariate analysis of variance approaches, regression models, two-stage line models, approaches to categorical data and techniques for analysing crossover designs. The theory is illustrated with examples, using real data brought to the authors during their work as statistical consultants.


Categorical Data Analysis by Example

Categorical Data Analysis by Example
Author: Graham J. G. Upton
Publisher: John Wiley & Sons
Total Pages: 212
Release: 2016-11-14
Genre: Mathematics
ISBN: 1119307864

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Introduces the key concepts in the analysis of categoricaldata with illustrative examples and accompanying R code This book is aimed at all those who wish to discover how to analyze categorical data without getting immersed in complicated mathematics and without needing to wade through a large amount of prose. It is aimed at researchers with their own data ready to be analyzed and at students who would like an approachable alternative view of the subject. Each new topic in categorical data analysis is illustrated with an example that readers can apply to their own sets of data. In many cases, R code is given and excerpts from the resulting output are presented. In the context of log-linear models for cross-tabulations, two specialties of the house have been included: the use of cobweb diagrams to get visual information concerning significant interactions, and a procedure for detecting outlier category combinations. The R code used for these is available and may be freely adapted. In addition, this book: Uses an example to illustrate each new topic in categorical data Provides a clear explanation of an important subject Is understandable to most readers with minimal statistical and mathematical backgrounds Contains examples that are accompanied by R code and resulting output Includes starred sections that provide more background details for interested readers Categorical Data Analysis by Example is a reference for students in statistics and researchers in other disciplines, especially the social sciences, who use categorical data. This book is also a reference for practitioners in market research, medicine, and other fields.


Applied Statistics in Agricultural, Biological, and Environmental Sciences

Applied Statistics in Agricultural, Biological, and Environmental Sciences
Author: Barry Glaz
Publisher: John Wiley & Sons
Total Pages: 672
Release: 2020-01-22
Genre: Technology & Engineering
ISBN: 0891183590

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Better experimental design and statistical analysis make for more robust science. A thorough understanding of modern statistical methods can mean the difference between discovering and missing crucial results and conclusions in your research, and can shape the course of your entire research career. With Applied Statistics, Barry Glaz and Kathleen M. Yeater have worked with a team of expert authors to create a comprehensive text for graduate students and practicing scientists in the agricultural, biological, and environmental sciences. The contributors cover fundamental concepts and methodologies of experimental design and analysis, and also delve into advanced statistical topics, all explored by analyzing real agronomic data with practical and creative approaches using available software tools. IN PRESS! This book is being published according to the “Just Published” model, with more chapters to be published online as they are completed.


Nonlinear Models for Repeated Measurement Data

Nonlinear Models for Repeated Measurement Data
Author: Marie Davidian
Publisher: Routledge
Total Pages: 360
Release: 2017-11-01
Genre: Mathematics
ISBN: 1351428152

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Nonlinear measurement data arise in a wide variety of biological and biomedical applications, such as longitudinal clinical trials, studies of drug kinetics and growth, and the analysis of assay and laboratory data. Nonlinear Models for Repeated Measurement Data provides the first unified development of methods and models for data of this type, with a detailed treatment of inference for the nonlinear mixed effects and its extensions. A particular strength of the book is the inclusion of several detailed case studies from the areas of population pharmacokinetics and pharmacodynamics, immunoassay and bioassay development and the analysis of growth curves.


Methods and Applications of Longitudinal Data Analysis

Methods and Applications of Longitudinal Data Analysis
Author: Xian Liu
Publisher: Elsevier
Total Pages: 531
Release: 2015-09-01
Genre: Mathematics
ISBN: 0128014822

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Methods and Applications of Longitudinal Data Analysis describes methods for the analysis of longitudinal data in the medical, biological and behavioral sciences. It introduces basic concepts and functions including a variety of regression models, and their practical applications across many areas of research. Statistical procedures featured within the text include: descriptive methods for delineating trends over time linear mixed regression models with both fixed and random effects covariance pattern models on correlated errors generalized estimating equations nonlinear regression models for categorical repeated measurements techniques for analyzing longitudinal data with non-ignorable missing observations Emphasis is given to applications of these methods, using substantial empirical illustrations, designed to help users of statistics better analyze and understand longitudinal data. Methods and Applications of Longitudinal Data Analysis equips both graduate students and professionals to confidently apply longitudinal data analysis to their particular discipline. It also provides a valuable reference source for applied statisticians, demographers and other quantitative methodologists. From novice to professional: this book starts with the introduction of basic models and ends with the description of some of the most advanced models in longitudinal data analysis Enables students to select the correct statistical methods to apply to their longitudinal data and avoid the pitfalls associated with incorrect selection Identifies the limitations of classical repeated measures models and describes newly developed techniques, along with real-world examples.


Repeated Measures Design with Generalized Linear Mixed Models for Randomized Controlled Trials

Repeated Measures Design with Generalized Linear Mixed Models for Randomized Controlled Trials
Author: Toshiro Tango
Publisher: CRC Press
Total Pages: 376
Release: 2017-09-14
Genre: Mathematics
ISBN: 1498747906

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Repeated Measures Design with Generalized Linear Mixed Models for Randomized Controlled Trials is the first book focused on the application of generalized linear mixed models and its related models in the statistical design and analysis of repeated measures from randomized controlled trials. The author introduces a new repeated measures design called S:T design combined with mixed models as a practical and useful framework of parallel group RCT design because of easy handling of missing data and sample size reduction. The book emphasizes practical, rather than theoretical, aspects of statistical analyses and the interpretation of results. It includes chapters in which the author describes some old-fashioned analysis designs that have been in the literature and compares the results with those obtained from the corresponding mixed models. The book will be of interest to biostatisticians, researchers, and graduate students in the medical and health sciences who are involved in clinical trials. Author Website:Data sets and programs used in the book are available at http://www.medstat.jp/downloadrepeatedcrc.html


Statistics Applied to Clinical Trials

Statistics Applied to Clinical Trials
Author: Ton J. Cleophas
Publisher: Springer Science & Business Media
Total Pages: 105
Release: 2013-11-11
Genre: Medical
ISBN: 9401595089

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In 1948 the first randomized controlled trial was published by the English Medical Research Council in the British Medical Journal. Until then, observations had been uncontrolled. Initially, trials frequently did not confirm the hypotheses to be tested. This phenomenon was attributed to low sensitivity due to small samples, as well as inappropriate hypotheses based on biased prior trials. Additional flaws were recognized and, subsequently, were better accounted for: carryover effects due to insufficient washout from previous treatments, time effects due to external factors and the natural history of the condition under study, bias due to asymmetry between treatment groups, lack of sensitivity due to a negative correlation between treatment responses, and so on. Such flaws, mainly of a technical nature, have been largely corrected and led to trials after 1970 being of significantly higher quality. The past decade has focused, in addition to technical aspects, on the need for circumspection in the planning and conducting of clinical trials. As a consequence, prior to approval, clinical trial protocols are now routinely scrutinized by different circumstantial organs, including ethics committees, institutional and federal review boards, national and international scientific organizations, and monitoring committees charged with conducting interim analyses. This book not only explains classical statistical analyses of clinical trials, but also addresses relatively novel issues, including equivalence testing, interim analyses, sequential analyses, and meta-analyses, and provides a framework of the best statistical methods currently available for such purposes. This book is not only useful for investigators involved in the field of clinical trials, but also for all physicians who wish to better understand the data of trials as currently published.