An Investigation Of The Potential Of Multi Modality Imaging In Three Dimensional Thick Tissue Microscopy PDF Download

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Multi-modality Microscopy

Multi-modality Microscopy
Author: Hanry Yu
Publisher: World Scientific Publishing Company
Total Pages: 324
Release: 2006
Genre: Science
ISBN:

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Based around recent lectures given at the prestigious Ritsumeikan conference, the tutorial and expository articles contained in this volume are an essential guide for practitioners and graduates alike who use stochastic calculus in finance. Among the eminent contributors are Paul Malliavin and Shinzo Watanabe, pioneers of Malliavin Calculus. The coverage also includes a valuable review of current research on credit risks in a mathematically sophisticated way contrasting with existing economics-oriented articles.


Three Dimensional Biomedical Imaging

Three Dimensional Biomedical Imaging
Author: Richard A. Robb
Publisher: Wiley-VCH
Total Pages: 344
Release: 1995
Genre: Medical
ISBN:

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Synthesizes for basic scientists and medical practitioners in any discipline the fundamentals, principles, historical evolution, current methods, and practical applications of three-dimensional imaging in medicine and biology. Compares all the major approaches and their benefits and limitations, and discusses such elements as multimodal imaging, computers, processing and visualization, measurement, and interpretation. Highly illustrated, including over 50 color plates. Annotation copyright by Book News, Inc., Portland, OR


Principles of Three Dimensional Imaging in Confocal Microscopes

Principles of Three Dimensional Imaging in Confocal Microscopes
Author: Min Gu
Publisher: World Scientific
Total Pages: 360
Release: 1996
Genre: Science
ISBN: 9789810225506

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This book discusses the various principles in confocal scanning microscopy which has become a useful tool in many practical fields including biological studies and industrial inspection. The methodology presented in this book is unique and is based on the concept of the three-dimensional transfer functions which have been developed by the author and his colleagues over the last five years. With the 3-D transfer functions, resolving power in 3-D confocal imaging can be defined in a unified way, different optical arrangements can be compared with an insight into their inter-relationship, and images of thick objects can be modeled in terms of the Fourier transform which makes the analysis easy. The aim of this book is to provide a systematic introduction to the concept of the 3-D transfer functions in various confocal microscopes, to describe the methods for the derivation of different 3-D transfer functions, and to explain the principles of 3-D confocal imaging in terms of these functions.


Multi-Modality Imaging

Multi-Modality Imaging
Author: Mauren Abreu de Souza
Publisher: Springer
Total Pages: 256
Release: 2018-11-29
Genre: Medical
ISBN: 331998974X

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This book presents different approaches on multi-modality imaging with a focus on biomedical applications. Medical imaging can be divided into two categories: functional (related to physiological body measurements) and anatomical (structural) imaging modalities. In particular, this book covers imaging combinations coming from the usual popular modalities (such as the anatomical modalities, e.g. X-ray, CT and MRI), and it also includes some promising and new imaging modalities that are still being developed and improved (such as infrared thermography (IRT) and photoplethysmography imaging (PPGI)), implying potential approaches for innovative biomedical applications. Moreover, this book includes a variety of tools on computer vision, imaging processing, and computer graphics, which led to the generation and visualization of 3D models, making the most recent advances in this area possible. This is an ideal book for students and biomedical engineering researchers covering the biomedical imaging field.


Contribution to Three-dimensional Fluorescence Microscopy Imaging Using Wavefront Encoding and Structured Illumination

Contribution to Three-dimensional Fluorescence Microscopy Imaging Using Wavefront Encoding and Structured Illumination
Author: Nurmohammed Patwary
Publisher:
Total Pages:
Release: 2017
Genre:
ISBN:

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Three-dimensional (3D) fluorescence microscopy (FM) is an integral part of biomedical research as it provides the necessary tool to investigate the interaction between the biomolecules in multiple dimensions (i.e. spatial, spectral, and temporal). This dissertation contributes toward two special types of FM: (i) computational optical sectioning microscopy (COSM), in which computational methods are used to improve the performance of the conventional imaging system, and (ii) structured illumination microscopy (SIM), which is used to increase the resolution of the optical microscope beyond the diffraction limit. A simplifying assumption of COSM is that the point spread function (PSF) does not change throughout the imaging volume; however, this assumption is not valid for optically thick samples (>5 µm), if the refractive index (RI) between the sample-mounting medium and the microscope objective (MO) lens’ immersion medium is different. Such cases require the use of computationally intensive depth-variant (DV) image restoration methods to avoid artifacts. To overcome this challenge, a wavefront encoded imaging system is developed, where we have demonstrated through simulation and experiment that a PSF does not change significantly up to a 60-µm imaging depth, which consequently improves the computational efficiency while restoring optically thick samples. Another contribution of this dissertation is investigating the impact of SA on SIM and the use of wavefront encoding to reduce the effect of SA on the SIM system. Data from the proof-of-concept setup was acquired and compared to the simulation to validate the implementations. Preliminary results demonstrate challenges that need to overcome, in order to be able to assess the impact of this approach on addressing SA satisfactorily. As an alternative approach, an image restoration method is developed and evaluated to improve the performance of SIM when the fringe visibility of the structured light is low, a condition that occurs when the sample is optically thick and/or the modulation frequency is high. Restoration results from simulated and experimental SIM raw images show improved signal to noise ratio (SNR) and adequate optical sectioning in 3D images, in which more details of fine structures are evident compared to results obtained with two existing computational methods.


Three-dimensional Microscopy

Three-dimensional Microscopy
Author:
Publisher:
Total Pages: 256
Release: 1995
Genre: Confocal microscopy
ISBN:

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Fluorescent Nanodiamonds

Fluorescent Nanodiamonds
Author: Huan-Cheng Chang
Publisher: John Wiley & Sons
Total Pages: 294
Release: 2018-11-12
Genre: Science
ISBN: 1119477085

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The most comprehensive reference on fluorescent nanodiamond physical and chemical properties and contemporary applications Fluorescent nanodiamonds (FNDs) have drawn a great deal of attention over the past several years, and their applications and development potential are proving to be manifold and vast. The first and only book of its kind, Fluorescent Nanodiamonds is a comprehensive guide to the basic science and technical information needed to fully understand the fundamentals of FNDs and their potential applications across an array of domains. In demonstrating the importance of FNDs in biological applications, the authors bring together all relevant chemistry, physics, materials science and biology. Nanodiamonds are produced by powerful cataclysmic events such as explosions, volcanic eruptions and meteorite impacts. They also can be created in the lab by high-pressure high-temperature treatment of graphite or detonating an explosive in a reactor vessel. A single imperfection can give a nanodiamond a specific, isolated color center which allows it to function as a single, trapped atom. Much smaller than the thickness of a human hair, a nanodiamond can have a huge surface area that allows it to bond with a variety of other materials. Because of their non-toxicity, nanodiamonds may be useful in biomedical applications, such as drug delivery and gene therapy. The most comprehensive reference on a topic of rapidly increasing interest among academic and industrial researchers across an array of fields Includes numerous case studies and practical examples from many areas of research and industrial applications, as well as fascinating and instructive historical perspectives Each chapter addresses, in-depth, a single integral topic including the fundamental properties, synthesis, mechanisms and functionalisation of FNDs The first book published by the key patent holder with his research group in the field of FNDs Fluorescent Nanodiamonds is an important working resource for a broad range of scientists and engineers in industry and academia. It will also be a welcome reference for instructors in chemistry, physics, materials science, biology and related fields.


Multi-modality Microscopy

Multi-modality Microscopy
Author: Hanry Yu
Publisher: World Scientific
Total Pages: 317
Release: 2006-05-08
Genre: Technology & Engineering
ISBN: 9814479128

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This book covers important aspects of modern optical microscopy and image restoration technologies. Instead of pure optical treatment, the book is delivered with the consideration of the scientists who utilize optical microscopy in their daily research. However, enough details are provided in basic imaging principles, optics and instrumentation in microscopy, spherical aberrations, deconvolution and image restoration. A number of microscopic technologies such as polarization, confocal and multi-photon microscopy are highlighted with their applications in biological and materials sciences/engineering.