Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download An In Silico Experimental Device To Study Drug Absorption Across Intestinal Epithelial Cell Barriers PDF full book. Access full book title An In Silico Experimental Device To Study Drug Absorption Across Intestinal Epithelial Cell Barriers.
| Author | : Yu Liu |
| Publisher | : |
| Total Pages | : 326 |
| Release | : 2005 |
| Genre | : |
| ISBN | : |
| Author | : Lan Garmire |
| Publisher | : |
| Total Pages | : 322 |
| Release | : 2007 |
| Genre | : |
| ISBN | : |
| Author | : Jennifer B. Dressman |
| Publisher | : CRC Press |
| Total Pages | : 432 |
| Release | : 2016-04-19 |
| Genre | : Medical |
| ISBN | : 1420077341 |
Oral Drug Absorption, Second Edition thoroughly examines the special equipment and methods used to test whether drugs are released adequately when administered orally. The contributors discuss methods for accurately establishing and validating in vitro/in vivo correlations for both MR and IR formulations, as well as alternative approaches for MR an
| Author | : Emanuel Lebenthal |
| Publisher | : Raven Press (ID) |
| Total Pages | : 854 |
| Release | : 1989 |
| Genre | : Medical |
| ISBN | : |
| Author | : Sarfaraz K. Niazi |
| Publisher | : CRC Press |
| Total Pages | : 585 |
| Release | : 2019-12-06 |
| Genre | : Medical |
| ISBN | : 1351593323 |
The Handbook of Pharmaceutical Manufacturing Formulations, Third Edition: Volume Four, Semisolid Products is an authoritative and practical guide to the art and science of formulating drugs for commercial manufacturing. With thoroughly revised and expanded content, this fourth volume of a six-volume set, compiles data from FDA and EMA new drug applications, patents and patent applications, and other sources of generic and proprietary formulations including author’s own experience, to cover the broad spectrum of cGMP formulations and issues in using these formulations in a commercial setting. A must-have collection for pharmaceutical manufacturers, educational institutions, and regulatory authorities, this is an excellent platform for drug companies to benchmark their products and for generic companies to formulate drugs coming off patent. Features: Largest source of authoritative and practical formulations, cGMP compliance guidance and self-audit suggestions Differs from other publications on formulation science in that it focuses on readily scalable commercial formulations that can be adopted for cGMP manufacturing Tackles common difficulties in formulating drugs and presents details on stability testing, bioequivalence testing, and full compliance with drug product safety elements Written by a well-recognized authority on drug and dosage form development including biological drugs and alternative medicines
| Author | : K. V. F. Jubb |
| Publisher | : Elsevier |
| Total Pages | : 494 |
| Release | : 2013-10-02 |
| Genre | : Technology & Engineering |
| ISBN | : 1483262855 |
Pathology of Domestic Animals, Volume 1 elaborates on the bone structure and diseases, as well as the genital, circulatory, and respiratory systems, of domestic animals. The manuscript first offers information on bones, joints, and synovial structures and diseases of joints, including adaptational deformities of the skeleton, metabolic diseases of bones, necrosis and inflammation of bones, and discontinuities of bone and the healing of fractures. The text then ponders on the circulatory and respiratory systems. Discussions focus on congenital anomalies of the heart and large vessels, myocardium, hypertrophy and dilation of the heart, pharynx and guttural pouches, larynx and trachea, lungs, and pleura and mediastinum. The publication examines the haemopoietic system and endocrine glands. Topics include blood and bone marrow, general reactions of erythrocytes to injury, lymphoreticular tissues, adrenal glands and paraganglia, and polycythaemia. The book then reviews the male and female genital systems. The manuscript is a valuable source of data for readers interested in the pathology of domestic animals.
| Author | : Sarfaraz K. Niazi |
| Publisher | : CRC Press |
| Total Pages | : 369 |
| Release | : 2016-04-19 |
| Genre | : Medical |
| ISBN | : 1420081276 |
The fourth volume in the series covers the techniques and technologies involved in the preparation of semisolid products such as ointments, creams, gels, suppositories, and special topical dosage forms. Drug manufacturers need a thorough understanding of the specific requirements that regulatory agencies impose on the formulation and efficacy deter
| Author | : William N. Charman |
| Publisher | : CRC Press |
| Total Pages | : 348 |
| Release | : 1992-04-22 |
| Genre | : Medical |
| ISBN | : 9780849363948 |
Lymphatic Transport of Drugs provides a thorough review of the determinants that affect the uptake and delivery of drugs and xenobiotics to the lymphatics. Factors affecting the transport and delivery of lipophilic drugs through the lymph after oral administration, lymphatic transport of polar drugs and macromolecules after gastrointestinal dosing, transport of drugs into the lymph after parenteral administration, and particulate drug delivery systems are among the topics examined in this volume. Lymphatic Transport of Drugs is primarily intended for pharmaceutical scientists who are attempting to alter the delivery of current therapeutic agents through formulation of prodrugs, as well as for researchers designing new drugs for lymph delivery.
| Author | : Carsten Ehrhardt |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 711 |
| Release | : 2007-12-22 |
| Genre | : Medical |
| ISBN | : 0387749012 |
This is a well thought-out, highly practical text covering contemporary ‘in vitro’ techniques for drug absorption studies. Starting at the molecular level of investigation, it continues with cell monolayer models (both primary and cell lines) and culminates with in situ techniques as a final testing format. In addition, chapters on high-throughput assays, in vitro-in vivo correlation, bioinformatics and regulatory issues are covered, giving a comprehensive overview of available models and techniques. Moreover, an appendix consisting of a number of practical protocols is available online, updated as needed, and should prove very helpful to apply the techniques directly to the benchside.
| Author | : Bruno Sarmento |
| Publisher | : Woodhead Publishing |
| Total Pages | : 410 |
| Release | : 2015-09-30 |
| Genre | : Science |
| ISBN | : 0081001142 |
This book intends to be an updated compilation of the most important buccal, gastric, intestinal, pulmonary, nasal, vaginal, ocular, skin and blood-brain barrier in vitro models for predicting the permeability of drugs. Concepts and Models for Drug Permeability Studies focuses on different approaches and comprises of various models. Each model describes the protocol of seeding and conservation, the application for specific drugs, and takes into account the maintenance of physiologic characteristics and functionality of epithelium, from the simplest immortalized cell-based monoculture to the most complex engineered-tissue models. Chapters also discuss the equivalence between in vitro cell and tissue models and in vivo conditions, highlighting how each model may provisionally resemble a different drug absorption route. Updated information regarding the most recent in vitro models to study the permeability of drugs Short and concise chapters covering all the biological barriers with interest in drug permeability A combination of bibliographic information related with individual models and footnote instructions of technical procedures for construction of cell and tissue-based models Simple and clear scientific content, adaptable for young scientists and experimented researchers
