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Altered Inheritance

Altered Inheritance
Author: Françoise Baylis
Publisher: Harvard University Press
Total Pages: 305
Release: 2019-09-17
Genre: Science
ISBN: 0674976711

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With the advent of CRISPR gene-editing technology, designer babies have become a reality. Françoise Baylis insists that scientists alone cannot decide the terms of this new era in human evolution. Members of the public, with diverse interests and perspectives, must have a role in determining our future as a species.


Altered Inheritance

Altered Inheritance
Author: Françoise Baylis
Publisher: Harvard University Press
Total Pages: 240
Release: 2019-09-17
Genre: Science
ISBN: 0674241967

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With the advent of CRISPR gene-editing technology, designer babies have become a reality. Françoise Baylis insists that scientists alone cannot decide the terms of this new era in human evolution. Members of the public, with diverse interests and perspectives, must have a role in determining our future as a species.


Heritable Human Genome Editing

Heritable Human Genome Editing
Author: The Royal Society
Publisher: National Academies Press
Total Pages: 239
Release: 2021-01-16
Genre: Medical
ISBN: 0309671132

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Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.


The Gene

The Gene
Author: Siddhartha Mukherjee
Publisher: Simon and Schuster
Total Pages: 624
Release: 2016-05-17
Genre: Medical
ISBN: 1476733538

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The #1 NEW YORK TIMES Bestseller The basis for the PBS Ken Burns Documentary The Gene: An Intimate History Now includes an excerpt from Siddhartha Mukherjee’s new book Song of the Cell! From the Pulitzer Prize–winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). “Sid Mukherjee has the uncanny ability to bring together science, history, and the future in a way that is understandable and riveting, guiding us through both time and the mystery of life itself.” —Ken Burns “Dr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for his virtuoso performance in The Gene: An Intimate History, in which he braids science, history, and memoir into an epic with all the range and biblical thunder of Paradise Lost” (The New York Times). In this biography Mukherjee brings to life the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. “Mukherjee expresses abstract intellectual ideas through emotional stories…[and] swaddles his medical rigor with rhapsodic tenderness, surprising vulnerability, and occasional flashes of pure poetry” (The Washington Post). Throughout, the story of Mukherjee’s own family—with its tragic and bewildering history of mental illness—reminds us of the questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In riveting and dramatic prose, he describes the centuries of research and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. “A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we are—and what our manipulation of those genes might mean for our future” (Milwaukee Journal-Sentinel), The Gene is the revelatory and magisterial history of a scientific idea coming to life, the most crucial science of our time, intimately explained by a master. “The Gene is a book we all should read” (USA TODAY).


DC Universe: Inheritance

DC Universe: Inheritance
Author: Devin Grayson
Publisher: Grand Central Publishing
Total Pages: 194
Release: 2009-11-29
Genre: Fiction
ISBN: 0446571083

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The award-winning author of the "Batman: Gotham Knights" comic pens this second book in an explosive four-book series featuring the greatest comic book heroes from the DC universe. Original.


A Daughter's Inheritance (The Broadmoor Legacy Book #1)

A Daughter's Inheritance (The Broadmoor Legacy Book #1)
Author: Tracie Peterson
Publisher: Bethany House
Total Pages: 384
Release: 2008-01-01
Genre: Fiction
ISBN: 144120220X

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From two bestselling authors comes intrigue and romance set in the opulent Thousand Islands resort area at the turn of the century.


A Troublesome Inheritance

A Troublesome Inheritance
Author: Nicholas Wade
Publisher: Penguin
Total Pages: 288
Release: 2014-05-06
Genre: Science
ISBN: 0698163796

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Drawing on startling new evidence from the mapping of the genome, an explosive new account of the genetic basis of race and its role in the human story Fewer ideas have been more toxic or harmful than the idea of the biological reality of race, and with it the idea that humans of different races are biologically different from one another. For this understandable reason, the idea has been banished from polite academic conversation. Arguing that race is more than just a social construct can get a scholar run out of town, or at least off campus, on a rail. Human evolution, the consensus view insists, ended in prehistory. Inconveniently, as Nicholas Wade argues in A Troublesome Inheritance, the consensus view cannot be right. And in fact, we know that populations have changed in the past few thousand years—to be lactose tolerant, for example, and to survive at high altitudes. Race is not a bright-line distinction; by definition it means that the more human populations are kept apart, the more they evolve their own distinct traits under the selective pressure known as Darwinian evolution. For many thousands of years, most human populations stayed where they were and grew distinct, not just in outward appearance but in deeper senses as well. Wade, the longtime journalist covering genetic advances for The New York Times, draws widely on the work of scientists who have made crucial breakthroughs in establishing the reality of recent human evolution. The most provocative claims in this book involve the genetic basis of human social habits. What we might call middle-class social traits—thrift, docility, nonviolence—have been slowly but surely inculcated genetically within agrarian societies, Wade argues. These “values” obviously had a strong cultural component, but Wade points to evidence that agrarian societies evolved away from hunter-gatherer societies in some crucial respects. Also controversial are his findings regarding the genetic basis of traits we associate with intelligence, such as literacy and numeracy, in certain ethnic populations, including the Chinese and Ashkenazi Jews. Wade believes deeply in the fundamental equality of all human peoples. He also believes that science is best served by pursuing the truth without fear, and if his mission to arrive at a coherent summa of what the new genetic science does and does not tell us about race and human history leads straight into a minefield, then so be it. This will not be the last word on the subject, but it will begin a powerful and overdue conversation.


Emotional Inheritance

Emotional Inheritance
Author: Galit Atlas
Publisher: Little, Brown Spark
Total Pages: 191
Release: 2022-01-25
Genre: Psychology
ISBN: 0316492116

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Award-winning psychoanalyst Dr. Galit Atlas draws on her patients' stories—and her own life experiences—to shed light on how generational trauma affects our lives in this "intimate, textured, compassionate" book (Jon Kabat-Zinn, author of The Healing Power of Mindfulness). The people we love and those who raised us live inside us; we experience their emotional pain, we dream their memories, and these things shape our lives in ways we don’t always recognize. Emotional Inheritance is about family secrets that keep us from living to our full potential, create gaps between what we want for ourselves and what we are able to have, and haunt us like ghosts. In this transformative book, Galit Atlas entwines the stories of her patients, her own stories, and decades of research to help us identify the links between our life struggles and the “emotional inheritance” we all carry. For it is only by following the traces those ghosts leave that we can truly change our destiny.


The Inheritance of Beauty

The Inheritance of Beauty
Author: Nicole Seitz
Publisher: HarperChristian + ORM
Total Pages: 321
Release: 2011-02-07
Genre: Fiction
ISBN: 1401685463

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Beauty, like truth, is enduring. But only one can set you free. The Inheritance of Beauty is a rich and enchanting story about 92-year-old George, forced to watch his beloved wife Maggie fade from Alzheimer’s—until a stranger arrives at their nursing home to bring the tragic past crashing back. Maggie Black came of age in the lush, fragrant lowcountry of South Carolina—spending her days with her beloved brother and the childhood sweetheart she would grow up to marry. But when a stranger arrived on the train one summer, Maggie couldn’t imagine the evil he would bring with him. And though she escaped with her life, the ramifications of that fateful summer would alter all of their lives forever. Now, some eighty years later, Maggie and her husband George are spending their remaining days in a nursing home, helpless as age slowly robs Maggie of her ability to communicate. When a mysterious package arrives, followed closely by a stranger whose identity haunts them, Maggie and George are hemmed in by a history they’d rather forget. As the truth reveals itself, George knows he must face the past and its lifetime of repercussions. It’s the only way to free himself and his precious wife—if it’s not too late. But George isn't sure how many lives were affected by the stranger in Levy . . . or why life must come full-circle now when he's running out of time Haunting southern fiction told through alternating points of view in the present and 1929 Includes discussion questions for book clubs Also by Nicole Seitz: Saving Cicadas,A Hundred Years of Happiness, and Trouble the Water


CRISPR People

CRISPR People
Author: Henry T. Greely
Publisher: MIT Press
Total Pages: 395
Release: 2022-03-01
Genre: Technology & Engineering
ISBN: 0262543885

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What does the birth of babies whose embryos had gone through genome editing mean--for science and for all of us? In November 2018, the world was shocked to learn that two babies had been born in China with DNA edited while they were embryos—as dramatic a development in genetics as the 1996 cloning of Dolly the sheep. In this book, Hank Greely, a leading authority on law and genetics, tells the fascinating story of this human experiment and its consequences. Greely explains what Chinese scientist He Jiankui did, how he did it, and how the public and other scientists learned about and reacted to this unprecedented genetic intervention. The two babies, nonidentical twin girls, were the first “CRISPR'd” people ever born (CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, is a powerful gene-editing method). Greely not only describes He's experiment and its public rollout (aided by a public relations adviser) but also considers, in a balanced and thoughtful way, the lessons to be drawn both from these CRISPR'd babies and, more broadly, from this kind of human DNA editing—“germline editing” that can be passed on from one generation to the next. Greely doesn't mince words, describing He's experiment as grossly reckless, irresponsible, immoral, and illegal. Although he sees no inherent or unmanageable barriers to human germline editing, he also sees very few good uses for it—other, less risky, technologies can achieve the same benefits. We should consider the implications carefully before we proceed.