Adenosine Receptors In Neurodegenerative Diseases PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Adenosine Receptors In Neurodegenerative Diseases PDF full book. Access full book title Adenosine Receptors In Neurodegenerative Diseases.
Author | : David Blum |
Publisher | : Academic Press |
Total Pages | : 281 |
Release | : 2017-03-10 |
Genre | : Medical |
ISBN | : 0128037458 |
Download Adenosine Receptors in Neurodegenerative Diseases Book in PDF, ePub and Kindle
Adenosine Receptors in Neurodegenerative Diseases covers the role of adenosine receptors in brain function, also focusing on related methodologies and perspectives in therapeutics. The book provides an up-to-date overview by the best specialists in the field, helping readers consider the importance of adenosine and expand the global impact and visibility of adenosine research in the CNS field. Chapters include adenosine biology and signaling, gene regulation, control of motor function, and novel adenosine-based therapies in the CNS. It is an ideal resource for researchers, advanced graduate students, clinicians, and industry scientists working in the fields of clinical neuroscience and molecular and cellular neuroscience. Comprehensive reference that details adenosine receptors in neurodegenerative disorders, with details on brain function and possible therapeutics Gives insights on how these receptors modulate the neurodegenerative outcomes in different disorders Edited by two of the leading researchers in the field regarding adenosine role in the brain in aging and neurodegenerative conditions
Author | : Pier Andrea Borea |
Publisher | : Humana Press |
Total Pages | : 593 |
Release | : 2018-07-28 |
Genre | : Medical |
ISBN | : 3319908081 |
Download The Adenosine Receptors Book in PDF, ePub and Kindle
This book traces the history of adenosine receptor research from molecular biology to medicinal chemistry to behavior, including their implications in disease and potential strategies as therapeutic targets. It provides the reader with a comprehensive overview of the adenosine receptors that includes information on all subtypes - A1, A2A, A2B and A3. Aspects addressed include the most up to date information on their functional distribution in the nervous and peripheral systems, behavioral roles in inflammation, cancer, pain and neurological diseases such as Huntington’s disease, Epilepsy, Parkinson’s disease and Alzheimer’s disease.
Author | : Hiroshi Kase |
Publisher | : Elsevier |
Total Pages | : 297 |
Release | : 1999-10-27 |
Genre | : Medical |
ISBN | : 0080525954 |
Download Adenosine Receptors and Parkinson's Disease Book in PDF, ePub and Kindle
This book is the first definitive overview on adenosine receptor antagonists and their application to the treatment of Parkinson's Disease. The effect of these novel non-dopamine drugs on vitro and in vivo systems clearly shows their potential for the treatment of this debilitating disease. This book covers how the Parkinson's disease antagonist drug, A2A, has been researched, developed, and tested. It is an essential book for researchers interested in the basal ganglia, purine biology, and Parkinson's Disease. Discusses the discovery and development of a novel non-dopaminomimetic agent for Parkinson's disease Provides the first definitive overview of adenosine antagonists and their role in the treatment of Parkinson's disease Presents a new mechanism of action of adenosine A2A receptor antagonists in motor function Proposes a hypothesis of adenosine A2A receptor function in the striatum Comprehensive overview of adenosine, its receptor subtypes, their antagonists/agonists from biochemistry, molecular biology, medicinal chemistry, physiology, pharmacology, and neurochemistry viewpoints
Author | : Constance N. Wilson |
Publisher | : Springer Science & Business Media |
Total Pages | : 656 |
Release | : 2009-07-28 |
Genre | : Medical |
ISBN | : 3540896155 |
Download Adenosine Receptors in Health and Disease Book in PDF, ePub and Kindle
Since their discovery approximately 25 years ago, adenosine receptors have now emerged as important novel molecular targets in disease and drug discovery. These proteins play important roles in the entire spectrum of disease from inflammation to immune suppression. Because of their expression on a number of different cell types and in a number of different organ systems they play important roles in specific diseases, including asthma, rheumatoid arthritis, Parkinson’s disease, multiple sclerosis, Alzheimer’s disease, heart disease, stroke, cancer, sepsis, and obesity. As a result of intense investigations into understanding the molecular structures and pharmacology of these proteins, new molecules have been synthesized that have high specificity for these proteins and are now entering clinical trials. These molecules will define the next new classes of drugs for a number of diseases with unmet medical needs.
Author | : J. A. Ribeiro |
Publisher | : Taylor & Francis Group |
Total Pages | : 252 |
Release | : 1989 |
Genre | : Medical |
ISBN | : |
Download Adenosine Receptors in the Nervous System Book in PDF, ePub and Kindle
A satellite Symposium on Adenosine Receptors in the Nervous System was held in April 1989 in Portugal. This book contains the manuscripts of the papers presented by the participants, who were from Europe, America and Asia.
Author | : Susan Masino |
Publisher | : Springer Science & Business Media |
Total Pages | : 680 |
Release | : 2012-08-30 |
Genre | : Medical |
ISBN | : 1461439035 |
Download Adenosine Book in PDF, ePub and Kindle
Homeostasis of key metabolites and metabolic health affects all bodily systems. Not surprisingly, altered metabolic function is associated with a wide spectrum of dysfunctions in the central nervous system – including developmental disorders, acute nervous system injury, and neurodegenerative disorders. Accordingly, metabolism-based therapies offer significant promise as new category of treatment options designed to limit, delay or reverse the disease process by reconstructing homeostatic functions. Increasingly it is appreciated that restoring metabolic health could promote normal nervous system activity, and improve behavior and cognition. Adenosine: A Key Link Between Metabolism and Central Nervous System Activity focusses on diverse aspects of adenosine, an evolutionarily conserved homeostatic bioenergetic regulator in the central nervous system. Because of its interrelationship with ATP (adenosine triphosphate), adenosine is integral to cell metabolism. At the same time, adenosine influences neuronal activity directly via receptors, and is involved in biochemical processes related to gene expression. Thus, adenosine is uniquely placed as a reciprocal and rapid link between changes in metabolism and changes in neuronal activity, and, on a longer time scale, to changes in gene expression and long term changes in cell function. Leaders in the field feature basic research on adenosine at the cellular level in the central nervous system, and relate these findings to its recognized potential in diverse acute and chronic disorders. This comprehensive overview of adenosine also highlights emerging adenosine-based treatments and associated opportunities for central nervous system disorders.
Author | : |
Publisher | : Academic Press |
Total Pages | : 523 |
Release | : 2014-08-28 |
Genre | : Science |
ISBN | : 0128013184 |
Download Adenosine Receptors in Neurology and Psychiatry Book in PDF, ePub and Kindle
This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume concentrates on adenosine receptor science, providing insights useful for actual drug discovery/development in neurology and psychiatry areas. Expertise of contributors Subject including practical drug development from basic science, as translational research taste Structure of contents focusing on two CNS areas for diseases (neurology and psychiatry)
Author | : Constance N. Wilson |
Publisher | : Springer |
Total Pages | : 652 |
Release | : 2009-08-29 |
Genre | : Medical |
ISBN | : 9783540896319 |
Download Adenosine Receptors in Health and Disease Book in PDF, ePub and Kindle
Since their discovery approximately 25 years ago, adenosine receptors have now emerged as important novel molecular targets in disease and drug discovery. These proteins play important roles in the entire spectrum of disease from inflammation to immune suppression. Because of their expression on a number of different cell types and in a number of different organ systems they play important roles in specific diseases, including asthma, rheumatoid arthritis, Parkinson’s disease, multiple sclerosis, Alzheimer’s disease, heart disease, stroke, cancer, sepsis, and obesity. As a result of intense investigations into understanding the molecular structures and pharmacology of these proteins, new molecules have been synthesized that have high specificity for these proteins and are now entering clinical trials. These molecules will define the next new classes of drugs for a number of diseases with unmet medical needs.
Author | : Raymond Chuen-Chung Chang |
Publisher | : BoD – Books on Demand |
Total Pages | : 104 |
Release | : 2019-08-28 |
Genre | : Medical |
ISBN | : 1789847362 |
Download Neuroprotection Book in PDF, ePub and Kindle
Neuroprotection is a strategy to prevent or delay the progression of chronic neurodegenerative diseases, acute neurological disorders, or even mental disorders. The major aim of this book is to focus on different approaches to achieve neuroprotection. In this book, there are chapters discussing imidazoline ligands and opioid ligands in Alzheimer's disease, the beneficial effects of adenosine A2A receptor antagonist, adrenergic receptor agonists and antagonists modulating microglial responses, and different approaches to achieve neuroprotection against aging-associated macular degeneration. This book will give insights to scientists in the field to stimulate their research, medical professionals to review their clinical practices, and others who would like to learn more about different neuroprotective approaches.
Author | : Gyorgy Hasko |
Publisher | : CRC Press |
Total Pages | : 377 |
Release | : 2006-07-20 |
Genre | : Medical |
ISBN | : 1420005774 |
Download Adenosine Receptors Book in PDF, ePub and Kindle
After a century of research, several lines of evidence now indicate that the ability of adenosine to directly control inflammatory cells has a major impact on the functions of the inflammatory and immune systems. Consequently, many promising therapeutic approaches are beginning to emerge that focus on the modulation of adenosine, including the deve