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Activation of Viruses by Host Proteases

Activation of Viruses by Host Proteases
Author: Eva Böttcher-Friebertshäuser
Publisher: Springer
Total Pages: 335
Release: 2018-05-22
Genre: Medical
ISBN: 3319754742

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This book will give an overview on viruses undergoing proteolytic activation through host proteases. The chapters will be organized in three themed parts, the first part describing respective viruses and their characteristics in detail. In the second part the molecular and cellular biology of the proteases involved as well as their physiological functions will be further explored. The third part will contain a chapter on protease inhibitors that are promising tools for antiviral therapy. This book will engage scholars in virology and medical microbiology as well as researchers with an interest in enzymology and protein structure and function relationship.


Activation of Viruses by Host Proteases

Activation of Viruses by Host Proteases
Author: Eva Böttcher-Friebertshäuser
Publisher: Springer
Total Pages: 0
Release: 2018-05-31
Genre: Medical
ISBN: 9783319754734

Download Activation of Viruses by Host Proteases Book in PDF, ePub and Kindle

This book will give an overview on viruses undergoing proteolytic activation through host proteases. The chapters will be organized in three themed parts, the first part describing respective viruses and their characteristics in detail. In the second part the molecular and cellular biology of the proteases involved as well as their physiological functions will be further explored. The third part will contain a chapter on protease inhibitors that are promising tools for antiviral therapy. This book will engage scholars in virology and medical microbiology as well as researchers with an interest in enzymology and protein structure and function relationship.


Activation of Viruses by Host Proteases

Activation of Viruses by Host Proteases
Author: Eva Böttcher-Friebertshäuser
Publisher: Springer
Total Pages: 0
Release: 2018-12-14
Genre: Medical
ISBN: 9783030092429

Download Activation of Viruses by Host Proteases Book in PDF, ePub and Kindle

This book will give an overview on viruses undergoing proteolytic activation through host proteases. The chapters will be organized in three themed parts, the first part describing respective viruses and their characteristics in detail. In the second part the molecular and cellular biology of the proteases involved as well as their physiological functions will be further explored. The third part will contain a chapter on protease inhibitors that are promising tools for antiviral therapy. This book will engage scholars in virology and medical microbiology as well as researchers with an interest in enzymology and protein structure and function relationship.


Viral Proteases and Their Inhibitors

Viral Proteases and Their Inhibitors
Author: Satya Prakash Gupta
Publisher: Academic Press
Total Pages: 516
Release: 2017-07-03
Genre: Science
ISBN: 0128096829

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Viral Proteases and Their Inhibitors provides a thorough examination of viral proteases from their molecular components, to therapeutic applications. As information on three dimensional structures and biological functions of these viral proteases become known, unexpected protein folds and unique mechanisms of proteolysis are realized. This book investigates how this facilitates the design and development of potent antiviral agents used against life-threatening viruses. Users will find descriptions of each virus that detail the structure and function of viral proteases, discuss the design and development of inhibitors, and analyze the structure-activity relationships of inhibitors. This book is ideal biochemists, virologists and those working on antiviral agents. Provides comprehensive, state-of-the-art coverage of virus infections, the virus lifecycle, and mechanisms of protease inhibition Analyzes structure-activity relationships of inhibitors of each viral protease Presents an in-depth view of the structure and function of viral proteases


Textbook of Influenza

Textbook of Influenza
Author: Robert G. Webster
Publisher: John Wiley & Sons
Total Pages: 684
Release: 2014-01-06
Genre: Medical
ISBN: 111863683X

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The Textbook of Influenza is a comprehensive resource covering all aspects of influenza, from the genetic and molecular biology of the virus through to clinical aspects of the disease and the latest drug developments and treatments. This new edition has been completely revised and reflects the integration of disciplines concerning the emergence, evolution, pathogenesis and control of influenza viruses in the field of human and veterinary public health. Textbook of Influenza examines the lessons learnt from the latest pandemic and provides the current state of knowledge for many yet unresolved issues related to virus origin, spread, pathogenesis and disease severity to better prepare for future pandemics. It covers the background to recent advances in influenza genomics and reverse genetics which have allowed the identification of virus virulence factors and the analysis and reconstruction of influenza viruses such as the 1918 Spanish flu strain. This new edition is divided into eight key sections, containing chapters co-written by international experts from both the clinical and scientific communities, covering: • Influenza Perspectives • Structure and Replication • Evolution and Ecology • Epidemiology and Surveillance • Immunology • Vaccines and Vaccine Development • Clinical Aspects and Antivirals • Public Health Textbook of Influenza is for all those working in the area of influenza including clinical and basic scientists, immunologists, molecular and structural virologists, public health officials and global pandemic control planners.


Concepts in Viral Pathogenesis

Concepts in Viral Pathogenesis
Author: A. L. Notkins
Publisher: Springer Science & Business Media
Total Pages: 418
Release: 2012-12-06
Genre: Science
ISBN: 1461252504

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The current proliferation of scientific information makes it difficult for even the most diligent reader to keep up with the latest developments in his/her own field, let alone other areas of interest. Review articles are one solution, but they too have become so voluminous and detailed that they often defeat the purpose for which they were intended. We have attempted to ease this problem by using a different format. In this volume on Concepts in Viral Pathogenesis, we have assembled a series of mini-reviews/editorials, 1,000 to 2,000 words in length. Each is a pithy distil lation of the state-of-the-art with emphasis on current thinking and unifying concepts rather than a compendium of the literature. The 53 articles, all written by active workers in their respective fields, are organized systemati cally so that the book will provide busy investigators, teachers and students of up-to-date information in a very brief and easily read a conceptual core able form. In addition, the authors have attempted to identify unresolved problems and point to future directions.


The HIV-1 Envelope Glycoproteins

The HIV-1 Envelope Glycoproteins
Author: Rogier Willem Sanders
Publisher: Amsterdam University Press
Total Pages: 342
Release: 2003-12-01
Genre: Medical
ISBN: 9789053566671

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The need for a vaccine against HIV is obvious, but the development of an effective vaccine has met with frustrations. The HIV envelope glycoproteins, residing in the viral membrane, are the sole viral proteins exposed on the outside of virus particles and.


Coronaviruses

Coronaviruses
Author: Helena J. Maier
Publisher: Humana
Total Pages: 278
Release: 2021-09-08
Genre: Medical
ISBN: 9781071609026

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This detailed new edition provides a comprehensive collection of protocols applicable to all members of the Coronavirinae sub-family currently and that are also transferrable to other fields of virology. Beginning with a section on detection, discovery, and evolution, the volume continues with coverage of propagation and titration of coronaviruses, genome manipulation, study of virus-host interactions, as well as imaging coronavirus infections. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Coronaviruses: Methods and Protocols, Second Edition serves as a valuable guide to researchers working to identify and control viruses with increased potential to cross the species barrier and to develop the diagnostics, vaccines, and antiviral therapeutics that are required to manage future outbreaks in both humans and animals.


Handbook of Antimicrobial Resistance

Handbook of Antimicrobial Resistance
Author: Matthias Gotte
Publisher: Springer
Total Pages: 0
Release: 2018-02-12
Genre: Medical
ISBN: 9781493906932

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While many volumes have been written about various aspects of antimicrobial resistance, this book is a comprehensive reference work. All manifestations of resistance are addressed: viral; bacterial, parasitical and fungal are given dedicated sections. The underlining molecular mechanisms, which depend not only on the microbe but on the specific drug (target), are highly diverse. This work discusses and compares the biological, biochemical and structural aspects of resistance and its evolution.


Proteases as Targets for Therapy

Proteases as Targets for Therapy
Author: Klaus, von der Helm
Publisher: Springer
Total Pages: 410
Release: 2012-10-10
Genre: Medical
ISBN: 9783642630231

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With contributions by numerous experts