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A Q&A Approach to Organic Chemistry

A Q&A Approach to Organic Chemistry
Author: Michael B. Smith
Publisher: CRC Press
Total Pages: 593
Release: 2020-05-17
Genre: Medical
ISBN: 1000060950

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A Q&A Approach to Organic Chemistry is a book of leading questions that begins with atomic orbitals and bonding. All critical topics are covered, including bonding, nomenclature, stereochemistry, conformations, acids and bases, oxidations, reductions, substitution, elimination, acyl addition, acyl substitution, enolate anion reactions, the Diels–Alder reaction and sigmatropic rearrangements, aromatic chemistry, spectroscopy, amino acids and proteins, and carbohydrates and nucleosides. All major reactions are covered. Each chapter includes end-of-chapter homework questions with the answer keys in an Appendix at the end of the book. This book is envisioned to be a supplementary guide to be used with virtually any available undergraduate organic chemistry textbook. This book allows for a "self-guided" approach that is useful as one studies for a coursework exam or as one reviews organic chemistry for postgraduate exams. Key Features: Allows a "self-guided tour" of organic chemistry Discusses all important areas and fundamental reactions of organic chemistry Classroom tested Useful as a study guide that will supplement most organic chemistry textbooks Assists one in study for coursework exams or allows one to review organic chemistry for postgraduate exams Includes 21 chapters of leading questions that covers all major topics and major reactions of organic chemistry


Novel Chemical Tools to Study Ion Channel Biology

Novel Chemical Tools to Study Ion Channel Biology
Author: Christopher Ahern
Publisher: Springer
Total Pages: 154
Release: 2015-09-17
Genre: Medical
ISBN: 1493928457

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This volume describes chemical approaches to assess ion channel structure, function and pharmacology. Topics discussed include the use of engineered ionizable side chains to obtain information on permeation pathways and the local environment; the modification of engineered cysteine side chains, including cysteine scanning mutagenesis and the attachment of fluorescent probes and bio-reactive tethers; and the nascent use of genetic code expansion, evaluating its applications to ion channel and membrane proteins. This comprehensive text provides multifaceted perspectives on the great diversity of state-of-the-art methods which take advantage of the ever-expanding chemical toolbox to study ion channel biology. Capturing the contributions and innovations of renowned laboratory researchers in transmembrane protein study for the first time, this book is comprehensive in scope. It covers a wide array of experimental approaches: photochemistry, novel biological tools, and innovative spectroscopy, all combined with traditional techniques of electrophysiology and molecular biology. Novel Chemical Tools to Study Ion Channel Biology, part of the bestselling Advances in Experimental Medicine and Biology series is ideal for researchers and advanced students interested in biochemistry, biophysics, fluorometry, electrophysiology, and chemical biology. .​


Quality Assurance and Quality Control in the Analytical Chemical Laboratory

Quality Assurance and Quality Control in the Analytical Chemical Laboratory
Author:
Publisher: CRC Press
Total Pages: 250
Release: 2016-04-19
Genre: Science
ISBN: 142008271X

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A Practical Tool for Learning New Methods Quality assurance and measurement uncertainty in analytical laboratories has become increasingly important. To meet increased scrutiny and keep up with new methods, practitioners very often have to rely on self-study. A practical textbook for students and a self-study tool for analytical laboratory employees, Quality Assurance and Quality Control in the Analytical Chemical Laboratory: A Practical Approach defines the tools used in QA/QC, especially the application of statistical tools during analytical data treatment. Unified Coverage of QA in Analytical Chemistry Clearly written and logically organized, this book delineates the concepts of practical QA/QC, taking a generic approach that can be applied to any field of analysis. Using an approach grounded in hands-on experience, the book begins with the theory behind quality control systems and then moves on to discuss examples of tools such as validation parameter measurements, the use of statistical tests, counting the margin of error, and estimating uncertainty. The authors draw on their experience in uncertainty estimation, traceability, reference materials, statistics, proficiency tests, and method validation to provide practical guidance on each step of the process. Extended Coverage of QC/QA in Analytical and Testing Laboratories Presenting guidance on all aspects of QA and measurement results, the book covers QC/QA in a more complex and extended manner than other books on this topic. This range of coverage supplies an integrated view on measures like the use of reference materials and method validation. With worked-out examples and Excel spreadsheets that users can use to try the concepts themselves, the book provides not only know-what but know-how.


Quality Assurance and Quality Control in the Analytical Chemical Laboratory

Quality Assurance and Quality Control in the Analytical Chemical Laboratory
Author: Piotr Konieczka
Publisher: CRC Press
Total Pages: 325
Release: 2018-03-26
Genre: Science
ISBN: 1315294990

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The second edition defines the tools used in QA/QC, especially the application of statistical tools during analytical data treatment. Clearly written and logically organized, it takes a generic approach applicable to any field of analysis. The authors begin with the theory behind quality control systems, then detail validation parameter measurements, the use of statistical tests, counting the margin of error, uncertainty estimation, traceability, reference materials, proficiency tests, and method validation. New chapters cover internal quality control and equivalence method, changes in the regulatory environment are reflected throughout, and many new examples have been added to the second edition.


Organic Chemistry

Organic Chemistry
Author: John McMurry
Publisher:
Total Pages: 1097
Release: 2007
Genre: Chemistry, Organic
ISBN: 9780495111283

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Quality Assurance in the Analytical Chemistry Laboratory

Quality Assurance in the Analytical Chemistry Laboratory
Author: D. Brynn Hibbert
Publisher: Oxford University Press
Total Pages: 320
Release: 2007-03-29
Genre: Science
ISBN: 9780198036722

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Analytical chemical results touch everyones lives can we eat the food? do I have a disease? did the defendant leave his DNA at the crime scene? should I invest in that gold mine? When a chemist measures something how do we know that the result is appropriate? What is fit for purpose in the context of analytical chemistry? Many manufacturing and service companies have embraced traditional statistical approaches to quality assurance, and these have been adopted by analytical chemistry laboratories. However the right chemical answer is never known, so there is not a direct parallel with the manufacture of ball bearings which can be measured and assessed. The customer of the analytical services relies on the quality assurance and quality control procedures adopted by the laboratory. It is the totality of the QA effort, perhaps first brought together in this text, that gives the customer confidence in the result. QA in the Analytical Chemistry Laboratory takes the reader through all aspects of QA, from the statistical basics and quality control tools to becoming accredited to international standards. The latest understanding of concepts such as measurement uncertainty and metrological traceability are explained for a working chemist or her client. How to design experiments to optimize an analytical process is included, together with the necessary statistics to analyze the results. All numerical manipulation and examples are given as Microsoft Excel spreadsheets that can be implemented on any personal computer. Different kinds of interlaboratory studies are explained, and how a laboratory is judged in proficiency testing schemes is described. Accreditation to ISO 17025 or OECD GLP is nearly obligatory for laboratories of any pretension to quality. Here the reader will find an introduction to the requirements and philosophy of accreditation. Whether completing a degree course in chemistry or working in a busy analytical laboratory, this book is a single source for an introduction into quality assurance.


Introductory Organic Chemistry and Hydrocarbons

Introductory Organic Chemistry and Hydrocarbons
Author: Caio Lima Firme
Publisher: CRC Press
Total Pages: 419
Release: 2019-08-28
Genre: Science
ISBN: 1351205773

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A novel proposal for teaching organic chemistry based on a broader and simplified use of quantum chemistry theories and notions of some statistical thermodynamic concepts aiming to enrich the learning process of the organic molecular properties and organic reactions. A detailed physical chemistry approach to teach organic chemistry for undergraduate students is the main aim of this book. A secondary objective is to familiarize undergraduate students with computational chemistry since most of illustrations of optimized geometries (plus some topological graphs) and information is from quantum chemistry outputs which will also enable students to obtain a deeper understanding of organic chemistry.


Quality Assurance for Environmental Analysis

Quality Assurance for Environmental Analysis
Author: E.A. Maier
Publisher: Elsevier
Total Pages: 648
Release: 1995-01-13
Genre: Science
ISBN: 9780080540078

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Quality assurance (QA) for environmental analysis is a growing feature of the nineties as is illustrated by the number of QA guidelines and systems which are being implemented nowadays. There is, however, often a huge gap between the implementation and respect of QA guidelines and the technical approach undertaken to improve and validate new analytical methods. This is particularly true for complex determinations involving multi-step methodologies such as those used in speciation and organic analyses. Quality assurance may also be considered from the technical point of view, which is the focus of this book. The techniques used in different analytical fields (inorganic, speciation and organic analysis) are critically reviewed (i.e. discussion of advantages and limitations) and existing tools for evaluating their performance are described (e.g. interlaboratory studies, use of certified reference materials). Particular reference is made to the activities of the Measurements and Testing Programme (BCR) of the European Commission towards the improvement of quality control of environmental analysis. The book has been written by experienced practitioners. By its nature, it serves as a practical reference for postgraduate students and environmental chemists who need a wide overview of the techniques used in environmental analysis and existing ways of evaluating the performance of relevant analytical methods. The critical discussions of the methods described, as well as the development of quality assurance aspects, makes it unique.


Theoretical Organic Chemistry

Theoretical Organic Chemistry
Author: C. Párkányi
Publisher: Elsevier
Total Pages: 621
Release: 1997-12-09
Genre: Science
ISBN: 9780080542720

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This volume is devoted to the various aspects of theoretical organic chemistry. In the nineteenth century, organic chemistry was primarily an experimental, empirical science. Throughout the twentieth century, the emphasis has been continually shifting to a more theoretical approach. Today, theoretical organic chemistry is a distinct area of research, with strong links to theoretical physical chemistry, quantum chemistry, computational chemistry, and physical organic chemistry. The objective in this volume has been to provide a cross-section of a number of interesting topics in theoretical organic chemistry, starting with a detailed account of the historical development of this discipline and including topics devoted to quantum chemistry, physical properties of organic compounds, their reactivity, their biological activity, and their excited-state properties.