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| Author | : Rhett Landen Martineau |
| Publisher | : |
| Total Pages | : 488 |
| Release | : 2008 |
| Genre | : Biological assay |
| ISBN | : |
| Author | : |
| Publisher | : |
| Total Pages | : 850 |
| Release | : 2008 |
| Genre | : Dissertations, Academic |
| ISBN | : |
| Author | : Robert M. Clark |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 529 |
| Release | : 2011-09-01 |
| Genre | : Political Science |
| ISBN | : 1461401895 |
Following the events of 9/11, the Administrator of the US Environmental Protection Agency created the Water Protection Task Force (WPTF), which identified water and wastewater systems as a major area of vulnerability to deliberate attack. The WPTF suggested that there are steps that can be taken to reduce these vulnerabilities and to make it as difficult as possible for potential saboteurs to succeed. The WPTF recommended that be scrutinized with renewed vigor to secure water and wastewater systems against these possible threats. It also recommended that water and wastewater systems have a response plan in place in the event an act of terrorism occurs. The WPTF identified water distribution networks as an area of special vulnerability and highlighted the need for rapid on-line detection methods that are accurate and have a wide detection range. As a result of these recommendations novel technologies from various fields of science and engineering are now addressing water security issues and water and wastewater utilities are looking for innovative solutions. Once such technologies are available, there will be a rapid implementation process that will present many business opportunities for the private sector. However, in addition to terrorist threats water and wastewater systems are inherently vulnerable to natural disasters such as earthquakes and floods. This volume will address the problems associated with both intended terrorist attacks and natural disasters affecting water or wastewater systems. The book is divided into parts based on the kinds of threats facing water and wastewater systems: (1) a direct attack on water and wastewater infrastructure storage reservoirs, and distribution and collection networks; (2) a cyber attack disabling the functionality of the water and wastewater systems or taking over control of key components which might result in system failures; and (3) a deliberate chemical or biological contaminant injection at one of the water distribution system’s nodes. It will examine unique plans, technological and managerial innovations for protecting such systems, and includes descriptions of projects that were implemented to respond to natural disasters. Case studies are presented that discuss existing projects and evaluate their performance, with an emphasis on providing guidelines and techniques that can be implemented by water and wastewater planners and managers to deal with natural and manmade disasters should they occur.
| Author | : Jan Roelof van der Meer |
| Publisher | : Springer Nature |
| Total Pages | : 153 |
| Release | : 2022-05-31 |
| Genre | : Mathematics |
| ISBN | : 3031025709 |
Bacterial reporters are live, genetically engineered cells with promising application in bioanalytics. They contain genetic circuitry to produce a cellular sensing element, which detects the target compound and relays the detection to specific synthesis of so-called reporter proteins (the presence or activity of which is easy to quantify). Bioassays with bacterial reporters are a useful complement to chemical analytics because they measure biological responses rather than total chemical concentrations. Simple bacterial reporter assays may also replace more costly chemical methods as a first line sample analysis technique. Recent promising developments integrate bacterial reporter cells with microsystems to produce bacterial biosensors. This lecture presents an in-depth treatment of the synthetic biological design principles of bacterial reporters, the engineering of which started as simple recombinant DNA puzzles, but has now become a more rational approach of choosing and combining sensing, controlling and reporting DNA 'parts'. Several examples of existing bacterial reporter designs and their genetic circuitry will be illustrated. Besides the design principles, the lecture also focuses on the application principles of bacterial reporter assays. A variety of assay formats will be illustrated, and principles of quantification will be dealt with. In addition to this discussion, substantial reference material is supplied in various Annexes. Table of Contents: Short History of the use of Bacteria for Biosensing and Bioreporting / Genetic Engineering Concepts / Measuring with Bioreporters / Epilogue
| Author | : Raju Khan |
| Publisher | : Academic Press |
| Total Pages | : 439 |
| Release | : 2021-08-25 |
| Genre | : Technology & Engineering |
| ISBN | : 0128236515 |
Early diagnosis of cancer and other non-oncological disorders gives a significant advantage for curing the disease and improving patient’s life expectancy. Recent advances in biosensor-based techniques which are designed for specific biomarkers can be exploited for early diagnosis of diseases. Biosensor Based Advanced Cancer Diagnostics covers all available biosensor-based approaches and comprehensive technologies; along with their application in diagnosis, prognosis and therapeutic management of various oncological disorders. Besides this, current challenges and future aspects of these diagnostic approaches have also been discussed. This book offers a view of recent advances and is also helpful for designing new biosensor-based technologies in the field of medical science, engineering and biomedical technology. Biosensor Based Advanced Cancer Diagnostics helps biomedical engineers, researchers, molecular biologists, oncologists and clinicians with the development of point of care devices for disease diagnostics and prognostics. It also provides information on developing user friendly, sensitive, stable, accurate, low cost and minimally invasive modalities which can be adopted from lab to clinics. This book covers in-depth knowledge of disease biomarkers that can be exploited for designing and development of a range of biosensors. The editors have summarized the potential cancer biomarkers and methodology for their detection, plus transferring the developed system to clinical application by miniaturization and required integration with microfluidic systems. Covers design and development of advanced platforms for rapid diagnosis of cancerous biomarkers Takes a multidisciplinary approach to sensitive transducers development, nano-enabled advanced imaging, miniaturized analytical systems, and device packaging for point-of-care applications Offers an insight into how to develop cost-effective diagnostics for early detection of cancer
| Author | : Séamus Higson |
| Publisher | : Elsevier |
| Total Pages | : 356 |
| Release | : 2012-08-21 |
| Genre | : Medical |
| ISBN | : 0857097180 |
Biomedical sensors are an essential tool in the detection and monitoring of a wide range of medical conditions from cancer to Parkinson’s disease. Biosensors for medical applications provides a comprehensive review of established, cutting edge and future trends in biomedical sensors and their applications. Part one focuses on key principles and transduction approaches, reviewing electrochemical, piezoelectric and nano-sized biosensors. Impedence interrogated affinity biosensors for medical applications and practical applications of enzyme biosensors are explored, before part two goes on to review specific medical applications. Biosensors for DNA and RNA detection and characterization, disease biomarker detection, and the use of affibodies as an alternative to antibodies in cancer marker biosensors are investigated, along with biosensors for drug testing and discovery, non-invasive measurements, and wearable biosensors for medical applications. With its distinguished editor and international team of expert contributors, Biosensors for medical applications is an essential guide for all those involved in the research, design, production and use of medical biosensors. Provides a comprehensive review of established, cutting edge and future trends in biomedical sensors and their applications Examines key principles and transduction approaches, reviewing electrochemical, piezoelectric and nano-sized biosensors Reviews biosensors for DNA and RNA detection and characterisation, disease biomarker detection, and the use of affibodies as an alternative to antibodies in cancer marker biosensors
| Author | : Paolo Bollella |
| Publisher | : MDPI |
| Total Pages | : 504 |
| Release | : 2021-01-27 |
| Genre | : Science |
| ISBN | : 3039438875 |
The present book is devoted to all aspects of biosensing in a very broad definition, including, but not limited to, biomolecular composition used in biosensors (e.g., biocatalytic enzymes, DNAzymes, abiotic nanospecies with biocatalytic features, bioreceptors, DNA/RNA, aptasensors, etc.), physical signal transduction mechanisms (e.g., electrochemical, optical, magnetic, etc.), engineering of different biosensing platforms, operation of biosensors in vitro and in vivo (implantable or wearable devices), self-powered biosensors, etc. The biosensors can be represented with analogue devices measuring concentrations of analytes and binary devices operating in the YES/NO format, possibly with logical processing of input signals. Furthermore, the book is aimed at attracting young scientists and introducing them to the field, while providing newcomers with an enormous collection of literature references.
| Author | : Tai Hyun Park |
| Publisher | : Springer Science & Business |
| Total Pages | : 294 |
| Release | : 2014-04-25 |
| Genre | : Medical |
| ISBN | : 9401786135 |
The “bioelectronic nose”, the device which has a similar function to the human smell sensing system, can be realized by combining the olfactory cells or receptors with nanotechnology. In the last two decades, much has been learned about the smell sensing mechanism in biological systems. With knowledge about the biological olfactory system and the techniques for the expression of biological receptor proteins, we are able to utilize biological materials and systems to mimic the biological olfactory system. In addition to the advances in biological and biotechnological area, nanotechnology has progressed to a great degree. The bioelectronic nose is a good example of the integration of biotechnology and nanotechnology. This book describes basic biological sciences of the olfactory system, biotechnology for the production of olfactory biological elements, and nanotechnology for the development of various sensing devices. The purpose of this book is to provide the reader with a concept, basic sciences, fundamental technologies, applications, and perspectives of the bioelectronic nose.
| Author | : Jin-Ming Lin |
| Publisher | : Springer |
| Total Pages | : 435 |
| Release | : 2017-10-25 |
| Genre | : Science |
| ISBN | : 9811053944 |
This book presents a detailed overview of the design, formatting, application, and development of microfluidic chips in the context of cell biology research, enumerating each element involved in microfluidics-based cell analysis, discussing its history, status quo, and future prospects, It also offers an extensive review of the research completed in the past decade, including numerous color figures. The individual chapters are based on the respective authors' studies and experiences, providing tips from the frontline to help researchers overcome bottlenecks in their own work. It highlights a number of cutting-edge techniques, such as 3D cell culture, microfluidic droplet technique, and microfluidic chip-mass spectrometry interfaces, offering a first-hand impression of the latest trends in the field and suggesting new research directions. Serving as both an elementary introduction and advanced guidebook, the book interests and inspires scholars and students who are currently studying microfluidics-based cell analysis methods as well as those who wish to do so.
| Author | : Alexandru Grumezescu |
| Publisher | : Academic Press |
| Total Pages | : 928 |
| Release | : 2016-09-28 |
| Genre | : Science |
| ISBN | : 0128043725 |
Nanobiosensors: Nanotechnology in the Agri-Food Industry, Volume 8, provides the latest information on the increasing demand for robust, rapid, inexpensive, and safe alternative technologies that monitor, test, and detect harmful or potentially dangerous foods. Due to their high sensitivity and selectivity, nanobiosensors have attracted attention for their use in monitoring not only biological contaminants in food, but also potential chemical and physical hazards. This book offers a broad overview regarding the current progress made in the field of nanosensors, including cutting-edge technological progress and the impact of these devices on the food industry. Special attention is given to the detection of microbial contaminants and harmful metabolotes, such as toxins and hormones, which have a great impact on both humans and animal health and feed. Includes the most up-to-date information on nanoparticles based biosensors and quantum dots for biological detection Provides application methods and techniques for research analysis for bacteriological detection and food testing Presents studies using analytical tools to improve food safety and quality analysis
