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3D Printing for Implantable Medical Devices: From Surgical Reconstruction to Tissue/Organ Regeneration

3D Printing for Implantable Medical Devices: From Surgical Reconstruction to Tissue/Organ Regeneration
Author: Julien Georges Didier Barthès
Publisher: Frontiers Media SA
Total Pages: 186
Release: 2021-03-01
Genre: Science
ISBN: 2889665097

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Dr. Julien Barthes is Collaborative Project Manager at PROTiP MEDICAL SAS. All other Topic Editors declare no competing interests with regards to the Research Topic subject.


Focal Controlled Drug Delivery

Focal Controlled Drug Delivery
Author: Abraham J. Domb
Publisher: Springer Science & Business Media
Total Pages: 700
Release: 2014-02-17
Genre: Medical
ISBN: 1461494346

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The concept of focal controlled drug delivery has been applied for treating illnesses that are localized to a certain tissue or organ. These delivery systems are applied directly to the diseased site and deliver a desired dose for an extended time period while minimizing systemic distribution of toxic drug. Controlled drug delivery systems have been focused on oral extended release formulations and on systemic delivery of small drugs and peptides. Despite the upsurge of interest in focal targeted drug delivery, there is currently no single reference text on the subject. By comparison, there are numerous authored and edited books on oral, systemic and transdermal drug delivery or books on biodegradable polymers as drug carriers. Thus, the aim of Focal Drug Delivery is to bring together leading experts and researchers in the field to provide an authoritative account of the essential pharmaceutical, technological, physiological and biological sciences underpinning the topic. In addition, the book will review advances in treatment options for diseases localized at a certain tissue or organ.


Organ Manufacturing

Organ Manufacturing
Author: Xiaohong Wang
Publisher: Nova Science Publishers
Total Pages: 0
Release: 2015
Genre: Artificial organs
ISBN: 9781634829571

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This is the first time that human organs, such as the heart, liver, kidney, stomach, uterus, skin, lung, pancreas and breast can be manufactured automatically and precisely for clinical transplantation, drug screening and metabolism model establishment. Headed by Professor Xiaohong Wang (also the founder and director) in the Center of Organ Manufacturing, Department of Mechanical Engineering, Tsinghua University, this group has focused on organ manufacturing for over ten years. A series of technical bottleneck problems, such as vascular and nerve system establishment in a construct, multiple cell types and material system incorporation, and stem cell sequential engagement, have been overcome one by one. Two technical approaches have been exploited extensively. One is multiple nozzle rapid prototyping (RP), additive manufacturing (AM), or three-dimension (3D) printing. The other is combined mold systems. More than 110 articles and 40 patents with a series of theories and practices have been published consequently. In the future, all the failed organs (including the brain) in the human body can be substituted easily like a small accessory part in a car. Everyone can get benefit from these techniques, which ultimately means that the lifespan of humans, therefore, can be greatly prolonged from this time point. This book examines the progress made in the field and the developments made by these researchers (and authors) in the field.


3D Printing in Medicine

3D Printing in Medicine
Author: Deepak M. Kalaskar
Publisher: Woodhead Publishing
Total Pages: 424
Release: 2022-10-18
Genre: Technology & Engineering
ISBN: 0323902200

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3D Printing in Medicine, Second Edition examines the rapidly growing market of 3D-printed biomaterials and their clinical applications. With a particular focus on both commercial and premarket tools, the book looks at their applications within medicine and the future outlook for the field. The chapters are written by field experts actively engaged in educational and research activities at the top universities in the world. The earlier chapters cover the fundamentals of 3D printing, including topics such as materials and hardware. The later chapters go on to cover innovative applications within medicine such as computational analysis of 3D printed constructs, personalized 3D printing - including 3D cell and organ printing and the role of AI - with a subsequent look at the applications of high-resolution printing, 3D printing in diagnostics, drug development, 4D printing, and much more. This updated new edition features completely revised content, with additional new chapters covering organs-on-chips, bioprinting regulations and standards, intellectual properties, and socio-ethical implications of organs-on-demand. Reviews a broad range of biomedical applications of 3D printing biomaterials and technologies Provides an interdisciplinary look at 3D printing in medicine, bridging the gap between engineering and clinical fields Includes completely updated content with additional new chapters, covering topics such as organs-on-chips, bioprinting regulations, intellectual properties, medical standards in 3D printing, and more


3D Printing of Pharmaceuticals

3D Printing of Pharmaceuticals
Author: Abdul W. Basit
Publisher: Springer
Total Pages: 240
Release: 2018-08-06
Genre: Medical
ISBN: 3319907557

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3D printing is forecast to revolutionise the pharmaceutical sector, changing the face of medicine development, manufacture and use. Potential applications range from pre-clinical drug development and dosage form design through to the fabrication of functionalised implants and regenerative medicine. Within clinical pharmacy practice, printing technologies may finally lead to the concept of personalised medicines becoming a reality. This volume aims to be the definitive resource for anyone thinking of developing or using 3D printing technologies in the pharmaceutical sector, with a strong focus on the translation of printing technologies to a clinical setting. This text brings together leading experts to provide extensive information on an array of 3D printing techniques, reviewing the current printing technologies in the pharmaceutical manufacturing supply chain, in particular, highlighting the state-of-the-art applications in medicine and discussing modern drug product manufacture from a regulatory perspective. This book is a highly valuable resource for a range of demographics, including academic researchers and the pharmaceutical industry, providing a comprehensive inventory detailing the current and future applications of 3D printing in pharmaceuticals. Abdul W. Basit is Professor of Pharmaceutics at the UCL School of Pharmacy, University College London. Abdul’s research sits at the interface between pharmaceutical science and gastroenterology, forging links between basic science and clinical outcomes. He leads a large and multidisciplinary research group, and the goal of his work is to further the understanding of gastrointestinal physiology by fundamental research. So far, this knowledge has been translated into the design of new technologies and improved disease treatments, many of which are currently in late-stage clinical trials. He has published over 350 papers, book chapters and abstracts and delivered more than 250 invited research presentations. Abdul is also a serial entrepreneur and has filed 25 patents and founded 3 pharmaceutical companies (Kuecept, Intract Pharma, FabRx). Abdul is a frequent speaker at international conferences, serves as a consultant to many pharmaceutical companies and is on the advisory boards of scientific journals, healthcare organisations and charitable bodies. He is the European Editor of the International Journal of Pharmaceutics. Abdul was the recipient of the Young Investigator Award in Pharmaceutics and Pharmaceutical Technology from the American Association of Pharmaceutical Scientists (AAPS) and is the only non-North American scientist to receive this award. He was also the recipient of the Academy of Pharmaceutical Sciences (APS) award. Simon Gaisford holds a Chair in Pharmaceutics and is Head of the Department of Pharmaceutics at the UCL School of Pharmacy, University College London. He has published 110 papers, 8 book chapters and 4 authored books. His research is focused on novel technologies for manufacturing medicines, particularly using ink-jet printing and 3D printing, and he is an expert in the physico-chemical characterisation of compounds and formulations with thermal methods and calorimetry.


3D Printing in Biomedical Engineering

3D Printing in Biomedical Engineering
Author: Sunpreet Singh
Publisher: Springer Nature
Total Pages: 346
Release: 2020-07-16
Genre: Technology & Engineering
ISBN: 9811554242

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This book gives a comprehensive overview of the rapidly evolving field of three-dimensional (3D) printing, and its increasing applications in the biomedical domain. 3D printing has distinct advantages like improved quality, cost-effectiveness, and higher efficiency compared to traditional manufacturing processes. Besides these advantages, current challenges and opportunities regarding choice of material, design, and efficiency are addressed in the book. Individual chapters also focus on select areas of applications such as surgical guides, tissue regeneration, artificial scaffolds and implants, and drug delivery and release. This book will be a valuable source of information for researchers and professionals interested in the expanding biomedical applications of 3D printing.


Essentials of 3D Biofabrication and Translation

Essentials of 3D Biofabrication and Translation
Author: Anthony Atala
Publisher: Academic Press
Total Pages: 441
Release: 2015-07-17
Genre: Science
ISBN: 0128010150

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Essentials of 3D Biofabrication and Translation discusses the techniques that are making bioprinting a viable alternative in regenerative medicine. The book runs the gamut of topics related to the subject, including hydrogels and polymers, nanotechnology, toxicity testing, and drug screening platforms, also introducing current applications in the cardiac, skeletal, and nervous systems, and organ construction. Leaders in clinical medicine and translational science provide a global perspective of the transformative nature of this field, including the use of cells, biomaterials, and macromolecules to create basic building blocks of tissues and organs, all of which are driving the field of biofabrication to transform regenerative medicine. Provides a new and versatile method to fabricating living tissue Discusses future applications for 3D bioprinting technologies, including use in the cardiac, skeletal, and nervous systems, and organ construction Describes current approaches and future challenges for translational science Runs the gamut of topics related to the subject, from hydrogels and polymers to nanotechnology, toxicity testing, and drug screening platforms


3D Printing for the Radiologist, E-Book

3D Printing for the Radiologist, E-Book
Author: Nicole Wake
Publisher: Elsevier Health Sciences
Total Pages: 242
Release: 2021-05-27
Genre: Medical
ISBN: 0323775748

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Comprehensive, yet concise, 3D Printing for the Radiologist presents an overview of three-dimensional printing at the point of care. Focusing on opportunities and challenges in radiology practice, this up-to-date reference covers computer-aided design principles, quality assurance, training, and guidance for integrating 3D printing across radiology subspecialties. Practicing and trainee radiologists, surgeons, researchers, and imaging specialists will find this an indispensable resource for furthering their understanding of the current state and future outlooks for 3D printing in clinical medicine. Covers a wide range of topics, including basic principles of 3D printing, quality assurance, regulatory perspectives, and practical implementation in medical training and practice. Addresses the challenges associated with 3D printing integration in clinical settings, such as reimbursement, regulatory issues, and training. Features concise chapters from a team of multidisciplinary chapter authors, including practicing radiologists, researchers, and engineers. Consolidates today’s available information on this timely topic into a single, convenient, resource.


3D Printing in Medicine

3D Printing in Medicine
Author: Frank J. Rybicki
Publisher: Springer
Total Pages: 138
Release: 2017-09-27
Genre: Medical
ISBN: 3319619241

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This book describes the fundamentals of three-dimensional (3D) printing, addresses the practical aspects of establishing a 3D printing service in a medical facility, and explains the enormous potential value of rendering images as 3D printed models capable of providing tactile feedback and tangible information on both anatomic and pathologic states. Individual chapters also focus on selected areas of applications for 3D printing, including musculoskeletal, craniomaxillofacial, cardiovascular, and neurosurgery applications. Challenges and opportunities related to training, materials and equipment, and guidelines are addressed, and the overall costs of a 3D printing lab and the balancing of these costs against clinical benefits are discussed. Radiologists, surgeons, and other physicians will find this book to be a rich source of information on the practicalities and expanding medical applications of 3D printing.


Tissue Engineering and Regenerative Medicine

Tissue Engineering and Regenerative Medicine
Author: Phuc Van Pham
Publisher: Springer
Total Pages: 225
Release: 2019-08-14
Genre: Science
ISBN: 303019857X

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This new series, based on a bi-annual conference and its topics, represents a major contribution to the emerging science of cancer research and regenerative medicine. Each volume brings together some of the most pre-eminent scientists working on cancer biology, cancer treatment, cancer diagnosis, cancer prevention and regenerative medicine to share information on currently ongoing work which will help shape future therapies. These volumes are invaluable resources not only for already active researchers or clinicians but also for those entering these fields, plus those in industry. Tissue Engineering and Regenerative Medicine is a proceedings volume which reflects papers presented at the 3rd bi-annual Innovations in Regenerative Medicine and Cancer Research conference; taken with its companion volume Stem Cells: Biology and Engineering it provides a complete overview of the papers from that meeting of international experts.