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This text critically examines the shortcomings of psychiatry; the flawed development of the diagnostic system, including the DSM-5; and the failure to advance the effectiveness of antipsychotics and antidepressants. Starting with an overview of the evolution of psychiatry, Dean explores the creation, use, and misuse of medications, a process largely driven by drug companies. Other chapters describe the benefits and risks of medications, the problems associated with rational prescribing, and the embrace of so-called novel therapies including hallucinogenic drugs and opioids. Chapters end with a set of clinical notes that provide specific recommendations to clinicians, families, patients, and other providers, emphasizing the risks and benefits of treatment with medications but also stressing alternative approaches. This book will challenge clinicians to think critically about the DSM-5 and the current systems of diagnosis and treatment of mental illnesses in the hopes of ultimately improving the lives of people with mental illnesses.