Yeast Genetic Networks PDF Download
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Author | : Attila Becskei |
Publisher | : Springer |
Total Pages | : 358 |
Release | : 2011-08-06 |
Genre | : |
ISBN | : 9781617790874 |
Download Yeast Genetic Networks Book in PDF, ePub and Kindle
Yeast Genetic Networks presents an analysis of small-scale gene networks in yeast. The text discusses different methods to analyze gene expression quantitatively, and describes a collection of mathematical and computational tools.
Author | : Trey Ideker |
Publisher | : |
Total Pages | : 156 |
Release | : 2001 |
Genre | : |
ISBN | : |
Download Validation and Refinement of Genetic Networks in Yeast Book in PDF, ePub and Kindle
Author | : Jeffrey S. Smith |
Publisher | : Humana |
Total Pages | : 0 |
Release | : 2016-09-17 |
Genre | : Science |
ISBN | : 9781493951826 |
Download Yeast Genetics Book in PDF, ePub and Kindle
Yeast Genetics: Methods and Protocols is a collection of methods to best study and manipulate Saccharomyces cerevisiae, a truly genetic powerhouse. The simple nature of a single cell eukaryotic organism, the relative ease of manipulating its genome and the ability to interchangeably exist in both haploid and diploid states have always made it an attractive model organism. Genes can be deleted, mutated, engineered and tagged at will. Saccharomyces cerevisiae has played a major role in the elucidation of multiple conserved cellular processes including MAP kinase signaling, splicing, transcription and many others. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Yeast Genetics: Methods and Protocols will provide a balanced blend of classic and more modern genetic methods relevant to a wide range of research areas and should be widely used as a reference in yeast labs.
Author | : Paul L. Bartel |
Publisher | : Oxford University Press, USA |
Total Pages | : 362 |
Release | : 1997 |
Genre | : Carrier proteins |
ISBN | : 9780195109382 |
Download The Yeast Two-hybrid System Book in PDF, ePub and Kindle
This volume, part of the Advances in Molecular Biology series, presents work by pioneers in the field and is the first publication devoted solely to the yeast two-hybrid system. It includes detailed protocols, practical advice on troubleshooting, and suggestions for future development. In addition, it illustrates how to construct an activation domain hybrid library, how to identify mutations that disrupt an interaction, and how to use the system in mammalian cells. Many of the contributors have developed new applications and variations of the technique.
Author | : Hiten D. Madhani |
Publisher | : CSHL Press |
Total Pages | : 124 |
Release | : 2007 |
Genre | : Biological models |
ISBN | : 0879697385 |
Download From a to [alpha] Book in PDF, ePub and Kindle
From a to&alphais a short supplemental textbook that uses control of yeast mating type as a model for many aspects of cell determination in general. Topics covered include gene silencing; genetic recombination; differentiation; combinatorial gene regulation; mRNA transport to establish asymmetric cell division; signal transduction; evolution of genetic networks; and various aspects of cell biology, including action of cytoskeleton and bud site selection. The book includes a foreword by Mark Ptashne, author of A Genetic Switch.
Author | : Anastasija Baryshnikova |
Publisher | : |
Total Pages | : |
Release | : 2013 |
Genre | : |
ISBN | : |
Download Mapping Genetic Interaction Networks in Yeast Book in PDF, ePub and Kindle
Author | : Jeremy Roop Roop |
Publisher | : |
Total Pages | : 120 |
Release | : 2016 |
Genre | : |
ISBN | : |
Download Genetic Determinants of Phenotypic Evolution in Saccharomyces Yeast Book in PDF, ePub and Kindle
Years of trait mapping studies have uncovered the genetic determinants underlying phenotypic evolution over both short and long timescales in a variety of organisms. A more general understanding of the mechanisms through which evolution produces phenotypic novelty, however, still remains out of reach. Many outstanding questions remain, among them how coding sequence divergence and gene expression divergence respectively contribute to trait evolution, as well as what role rare and large effect genetic variants play in the genetic networks underlying evolving phenotypes. Using Saccharomyces yeast as a genetically tractable model system in which to probe these questions, we identify and dissect several examples of trait divergence within and between yeast species. We first investigate an instance of intraspecific variation among yeasts isolated from a single population, finding that large effect rare variants at hypermutable loci are drivers of many common morphological and growth phenotypes. Next, in a comparison of both recently-diverged and long-diverged species, we investigate the role that gene expression variation plays in phenotypic evolution. We find evidence in multiple gene networks for complex and coherent regulatory evolution, and in one instance we succeed in identifying the loci that effect this change, as well as several phenotypic novelties they produce. Collectively, these investigations will contribute to the growing body of literature that describe the genetic mechanisms that underlie phenotypic change and seek, eventually, to achieve a greater understanding of basic evolutionary principles.
Author | : Johannes H. de Winde |
Publisher | : Springer Science & Business Media |
Total Pages | : 375 |
Release | : 2008-01-26 |
Genre | : Science |
ISBN | : 354037003X |
Download Functional Genetics of Industrial Yeasts Book in PDF, ePub and Kindle
In recent years, new yeast species have proven their value and novel biotechnological applications have emerged. This book compiles the multi-faceted genetic repertoire of several yeasts relevant to modern biotechnology, and describes their utilization in research and application in the light of their genetic make-up and physiological characteristics. Moreover, the book presents a thorough overview of a wide array of methodologies from classical genetics to modern genomics technologies that have been and are being used in functional analysis of yeasts.
Author | : Gerald R. Fink |
Publisher | : Gulf Professional Publishing |
Total Pages | : 786 |
Release | : 2002 |
Genre | : Science |
ISBN | : 9780121822545 |
Download Guide to Yeast Genetics and Molecular and Cell Biology, Part C Book in PDF, ePub and Kindle
This volume and its companion, Volume 350, are specifically designed to meet the needs of graduate students and postdoctoral students as well as researchers, by providing all the up-to-date methods necessary to study genes in yeast. Procedures are included that enable newcomers to set up a yeast laboratory and to master basic manipulations. Relevant background and reference information given for procedures can be used as a guide to developing protocols in a number of disciplines. Specific topics addressed in this book include cytology, biochemistry, cell fractionation, and cell biology.
Author | : Jason B. Wolf |
Publisher | : Oxford University Press, USA |
Total Pages | : 348 |
Release | : 2000 |
Genre | : Science |
ISBN | : 9780195128062 |
Download Epistasis and the Evolutionary Process Book in PDF, ePub and Kindle
Over the last two decades, research into epistasis has seen explosive growth and has moved the focus of research in evolutionary genetics from a traditional additive approach. We now know the effects of genes are rarely independent, and to reach a fuller understanding of the process of evolution we need to look at gene interactions as well as gene-environment interactions. This book is an overview of non-additive evolutionary genetics, integrating all work to date on all levels of evolutionary investigation of the importance of epistasis in the evolutionary process in general. It includes a historical perspective on this emerging field, in-depth discussion of terminology, discussions of the effects of epistasis at several different levels of biological organization and combinations of theoretical and experimental approaches to analysis.