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| Author | : Jean-Marc Sabatier |
| Publisher | : Frontiers Media SA |
| Total Pages | : 271 |
| Release | : 2022-09-29 |
| Genre | : Science |
| ISBN | : 2832501141 |
| Author | : Jean-Marc Sabatier |
| Publisher | : Frontiers Media SA |
| Total Pages | : 252 |
| Release | : 2021-07-09 |
| Genre | : Science |
| ISBN | : 2889669912 |
| Author | : Akira Ohsaka |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 568 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 1468408895 |
During the past two decades, research on animal, plant, and microbial toxins has expanded rapidly, and new and exciting information has appeared to clarify both the clinical and therapeutic aspects of intoxication and, even more impor tant, to help us understand more exactly the structure and the mode of action of toxins on a molecular basis. Because of the interdisciplinary nature of toxin research, it is of vital impor tance that workers specializing in its different aspects should make a particular effort to exchange and keep up with new developments in this rapidly-expanding field. This has been one of the main purposes of the series of international meetings that have been held over the past ten years. The increasing interest in the results of toxin research can be explained partly by the growing general preoccupation with pollution and its toxic effects, which means that more anq more specialists in other fields are finding it necessary to keep in touch with current research into naturally occurring toxins. The papers in these volumes were presented at the Fourth International Symposium on Animal, Plant and Microbial Toxins, organized by the Inter national Society on Toxicology, held in Tokyo in September, 1974. The editors have decided to include both original reports and review articles, arranged according to disciplines. Editing has been kept to the minimum necessary for adequate comprehension of the materials.
| Author | : Jan-Peter Hildebrandt |
| Publisher | : Walter de Gruyter GmbH & Co KG |
| Total Pages | : 547 |
| Release | : 2023-07-04 |
| Genre | : Science |
| ISBN | : 3110728621 |
This book series is based on the book "Biogene Gifte", 3. Edition, published 2010 by Wissenschaftliche Verlagsgesellschaft Stuttgart in German language. Because of the enormous increase in knowledge in the field of natural poisons and venoms the topic is now covered in 5 volumes in English language. The focus of this volume is on the toxic ingredients of animal poisons and venoms, their chemical structures, their effects and modes of actions in target organisms, and on the biology of poisonous or venomous animals. It highlights the symptoms of poisoning or envenoming in humans or animals, cite case reports were available, and gives hints on poisoning prevention and on potential treatments.
| Author | : 3Island Press |
| Publisher | : |
| Total Pages | : 592 |
| Release | : 1976-08-01 |
| Genre | : |
| ISBN | : 9781468408904 |
| Author | : Em. Pozzi-Escot |
| Publisher | : JOHN WILEY & SONS |
| Total Pages | : 41 |
| Release | : 2015-11-16 |
| Genre | : |
| ISBN | : |
Our knowledge of the toxins is of quite recent date. It is hardly twenty years since we began to acquire a knowledge of the facts that are detailed in this volume, and to which modern medicine owes its most recent and marvelous progress, particularly in serotherapy. In this volume we have studied, besides the true toxins—substances of cellular origin and of albuminoid nature and unknown composition—other toxic substances, the nitrogenized alkaloidal bases introduced into science through the researches of Selmi, Armand Gautier, and von Behring, and which are highly hydrogenized nitrogenous crystallizable principles of definite chemical composition—the products of the more or less advanced breaking down of albuminoids. Although these principles differ widely, by reason of their physiological properties as a whole, from the toxic albuminoids, or true toxins, it appears proper to consider them as products of the advanced decomposition of these toxins—and in this respect their study becomes imperative, the more so as they are very frequently encountered together with the toxins, particularly in serpent-venoms, where their action is exerted in addition to that of the true toxins. In the first volume of this collection we dwelt on the essentially reducing nature of the cellular functionation. To this functionation—causing the splitting up or decomposition by hydrolysis of nitrogenized albuminoid foods—is due the formation of these toxic basic products within the organism, whether normally, or because of certain pathological conditions. This alone suffices to show that, during physiological life, oxygen plays an essentially antitoxic rôle within the organism. It is hoped that this succinct résumé, which it has been sought to make as clear as possible, will be of service to those who, while not scientists actively engaged in scientific progress, desire to be abreast of the knowledge of modern evolution, but yet are not in a position to consult original papers or large treatises.
| Author | : Akira Ohsaka |
| Publisher | : |
| Total Pages | : 562 |
| Release | : 1976 |
| Genre | : Poisons |
| ISBN | : |
| Author | : P. Gopalakrishnakone |
| Publisher | : Springer |
| Total Pages | : 502 |
| Release | : 2018-03-14 |
| Genre | : Medical |
| ISBN | : 9789400764484 |
In recent years, the field of Toxinology has expanded substantially. On the one hand it studies venomous animals, plants and micro organisms in detail to understand their mode of action on targets. While on the other, it explores the biochemical composition, genomics and proteomics of toxins and venoms to understand their three interaction with life forms (especially humans), development of antidotes and exploring their pharmacological potential. Therefore, Toxinology has deep linkages with biochemistry, molecular biology, anatomy and pharmacology. In addition, there is a fast developing applied subfield, clinical toxinology, which deals with understanding and managing medical effects of toxins on human body. Given the huge impact of toxin-based deaths globally, and the potential of venom in generation of drugs for so-far incurable diseases (for example, Diabetes, Chronic Pain), the continued research and growth of the field is imminent. This has led to the growth of research in the area and the consequent scholarly output by way of publications in journals and books. Despite this ever growing body of literature within biomedical sciences, there is still no all-inclusive reference work available that collects all of the important biochemical, biomedical and clinical insights relating to Toxinology. The Handbook of Toxinology aims to address this gap and cover the field of Toxinology comprehensively.
| Author | : Osmo Otto Paivio Hanninen; Mustafa Atalay; B.P. Mansourian; A. Wojtezak; S.M. Mahfouz; Harry Majewski; Elaine Elisabetsky; Nina L. Etkin; Ralph Kirby; T.G. Downing and M.I. El Gohary |
| Publisher | : EOLSS Publications |
| Total Pages | : 468 |
| Release | : 2010-10-12 |
| Genre | : |
| ISBN | : 1848263813 |
Medical and Health Sciences is a component of Encyclopedia of Biological, Physiological and Health Sciences in the global Encyclopedia of Life Support Systems (EOLSS), which is an integrated compendium of twenty one Encyclopedias. These volume set contains several chapters, each of size 5000-30000 words, with perspectives, applications and extensive illustrations. It carries state-of-the-art knowledge in the fields of Medical and Health Sciences and is aimed, by virtue of the several applications, at the following five major target audiences: University and College Students, Educators, Professional Practitioners, Research Personnel and Policy Analysts, Managers, and Decision Makers and NGOs.
| Author | : C.-Y. Lee |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 1162 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 3642669131 |
The past decade has been a period of explosion of knowledge on the chemistry and pharmacology of snake toxins. Thanks to the development of protein chemistry, nearly a hundred snake toxins have been purified and sequenced, representing one of the largest families of sequenced proteins. Moreover, the mode of action of these toxins has been largely elucidated by the concerted efforts of pharmacologists, electro physiologists, and biochemists. As a result of these studies, some of the snake toxins, e.g., a-bungarotoxin and cobra neurotoxins, have been extensively used as specific markers in the study of the acetylcholine receptors. Indeed, without the discovery of these snake toxins, our knowledge of the structure and function of nicotinic acetylcholine receptors would not have advanced so rapidly. The contribution of snake venom research to the biomedical sciences is not limited to the study of cholinergic receptors. Being one of the most concentrated enzyme sources in nature, snake venoms are also valuable tools in biochemical research. Venom phosphodiesterase, for example, has been widely used for structural studies of nucleic acids; proteinase, for the sequence studies of proteins and pep tides ; phospholipase A , for lipid research; and L-amino acid oxidase for identifying optical z isomers of amino acids. Furthermore, snake venoms have proven to be useful agents for clarifying some basic concepts on blood coagulation and some venom enzymes, e.g., thrombin-like enzymes and pro coagulants have been used as therapeutic agents.
