Vaccine Design PDF Download
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| Author | : Sunil Thomas |
| Publisher | : Humana |
| Total Pages | : 546 |
| Release | : 2021-12-17 |
| Genre | : Science |
| ISBN | : 9781071618912 |
Download Vaccine Design Book in PDF, ePub and Kindle
This volume provides a practical guide providing step-by-step methods and protocols on vaccine development and production. Divided into three volumes, Volume 3: Resources for Vaccine Development guides readers through chapters on vaccine adjuvants, vaccine vectors, production, vaccine delivery systems, vaccine bioinformatics, vaccine regulation, and intellectual property. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and practical, Vaccine Design: Methods and Protocols, Second Edition, Volume 3: Resources for Vaccine Development aims to be a useful practical guide to researchers to help further their study in this field.
| Author | : Michael F. Powell |
| Publisher | : Springer |
| Total Pages | : 977 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 1461518237 |
Download Vaccine Design Book in PDF, ePub and Kindle
When my interest was first drawn to the phenomenon of vaccination for virus diseases in the late 1930s, the state of the art and the science of vaccine design was not far advanced beyond the time of Jenner at the end of the 18th century and of Pasteur a century later. In the 1930s it was still believed that for the induction of immunity to a virus-caused disease the experience of infection was required, but not for a toxin-caused disease such as diphtheria or tetanus, for which a chemically detoxified antigen was effective for immu nization. This prompted the question as to whether it might be possible to produce a similar effect for virus diseases using nonreplicating antigens. When in the 1930s and 1940s it was found possible to propagate influenza viruses in the chick embryo, protective effects could be induced without the need to experience infection by the use of a sufficient dose of a noninfectious influenza virus preparation. Later in the 1940s, it became possible to propagate polio and other viruses in cultures of human and monkey tissue and to immunize against other virus diseases in the same way. Later, with the advent of the era of molecular biology and genetic engineering, antigens and vaccines could be produced in new and creative ways, using either replicating or nonreplicating forms of the appropriate antigens for inducing a dose-related protective state.
| Author | : Joo Chuan Tong |
| Publisher | : Elsevier |
| Total Pages | : 164 |
| Release | : 2013-07-31 |
| Genre | : Medical |
| ISBN | : 1908818417 |
Download Computer-Aided Vaccine Design Book in PDF, ePub and Kindle
Computational pre-screening of antigens is now routinely applied to the discovery of vaccine candidates. Computer-aided vaccine design is a comprehensive introduction to this exciting field of study. The book is intended to be a textbook for researchers and for courses in bioinformatics, as well as a laboratory reference guide. It is written mainly for biologists who want to understand the current methods of computer-aided vaccine design. The contents are designed to help biologists appreciate the underlying concepts and algorithms used, as well as limitations of the methods and strategies for their use. Chapters include: MHC and T cell responses; Immunoglobulins and B cell responses; Scientific publications and databases; Database design; Computational T cell vaccine design; Computational B cell vaccine design; infectious disease informatics; Vaccine safety and quality assessments; and Vaccine adjuvant informatics. Essential reading for any biologist who wants to understand methods of computer-aided vaccine design Description of available data sources and publicly available software, with detailed analysis of strengths and weaknesses Theoretical concepts and practical examples of database design and development for a virtual screening campaign
| Author | : M. Elizabeth Halloran |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 390 |
| Release | : 2009-10-27 |
| Genre | : Medical |
| ISBN | : 0387686363 |
Download Design and Analysis of Vaccine Studies Book in PDF, ePub and Kindle
As well as being a reference for the design, analysis, and interpretation of vaccine studies, the text covers all design and analysis stages, from vaccine development to post-licensure surveillance, presenting likelihood, frequentists, and Bayesian approaches.
| Author | : Sunil Thomas |
| Publisher | : |
| Total Pages | : 873 |
| Release | : 2016 |
| Genre | : Vaccines |
| ISBN | : 9781493933877 |
Download Vaccine Design Book in PDF, ePub and Kindle
| Author | : Sunil Thomas |
| Publisher | : Humana |
| Total Pages | : 0 |
| Release | : 2016-04-14 |
| Genre | : Medical |
| ISBN | : 9781493933884 |
Download Vaccine Design Book in PDF, ePub and Kindle
This text provides a practical guide providing step-by-step protocol to design and develop vaccines. Chapters detail protocols for developing novel vaccines against infectious bacteria, viruses, fungi, and parasites for humans and animals. Volume 2: Vaccines for Veterinary Diseases includes vaccines for farm animals and fishes, vaccine vectors and production, vaccine delivery systems, vaccine bioinformatics, vaccine regulation and intellectual property. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Vaccine Design: Methods and Protocols, Volume 2: Vaccines for Veterinary Diseases aims to ensure successful results in the further study of this vital field.
| Author | : Barry R. Bloom |
| Publisher | : Academic Press |
| Total Pages | : 666 |
| Release | : 2016-06-23 |
| Genre | : Medical |
| ISBN | : 012805400X |
Download The Vaccine Book Book in PDF, ePub and Kindle
The Vaccine Book, Second Edition provides comprehensive information on the current and future state of vaccines. It reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, problems encountered when producing vaccines, how clinical vaccine trials are designed, and how to introduce vaccines into widespread use. Although vaccines are now available for many diseases, there are still challenges ahead for major diseases, such as AIDS, tuberculosis, and malaria. This book is designed for students, researchers, public health officials, and all others interested in increasing their understanding of vaccines. It answers common questions regarding the use of vaccines in the context of a rapidly expanding anti-vaccine environment. This new edition is completely updated and revised with new and unique topics, including new vaccines, problems of declining immunization rates, trust in vaccines, the vaccine hesitancy, and the social value of vaccines for the community vs. the individual child’s risk. Provides insights into diseases that could be prevented, along with the challenges facing research scientists in the world of vaccines Gives new ideas about future vaccines and concepts Introduces new vaccines and concepts Gives ideas about challenges facing public and private industrial investors in the vaccine area Discusses the problem of declining immunization rates and vaccine hesitancy
| Author | : Rino Rappuoli |
| Publisher | : Caister Academic Press Limited |
| Total Pages | : 0 |
| Release | : 2011 |
| Genre | : Medical |
| ISBN | : 9781904455745 |
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In this book, expert international authors critically review the current cutting-edge research in vaccine design and development. Particular emphasis is given to new approaches and technologies.
| Author | : W. John W. Morrow |
| Publisher | : John Wiley & Sons |
| Total Pages | : 552 |
| Release | : 2012-06-12 |
| Genre | : Medical |
| ISBN | : 1118345347 |
Download Vaccinology Book in PDF, ePub and Kindle
Covering all aspects of vaccine research and development in one volume, this authoritative resource takes a comprehensive and systematic approach to the science of vaccinology focusing not only on basic science, but also on the many stages required to commercialize and navigate the regulatory requirements for human application, both in the United States and Europe. Reviews in detail the process of designing a vaccine, from the initial stages of antigen discovery to human application Includes evaluation of vaccine efficacy and safety Details clinical trial design, including regulatory requirements Discusses the emerging field of active cellular immunotherapy Vaccinology: Principles and Practice provides an invaluable resource for clinicians, scientific and medical researchers, lecturers and postdoctoral fellows working in the field of vaccines.
| Author | : Sunil Thomas |
| Publisher | : Springer Nature |
| Total Pages | : 702 |
| Release | : 2021-12-16 |
| Genre | : Science |
| ISBN | : 1071618849 |
Download Vaccine Design Book in PDF, ePub and Kindle
This volume provides a practical guide providing step-by-step protocol to design and develop vaccines for human diseases. Divided into three volumes, Volume 1: Vaccines for Human Diseases guides readers through an introductory section on future challenges for vaccinologists and the immunological mechanism of vaccines. Chapters focus on design of human vaccines for viral, bacterial, fungal, and parasitic diseases as well as tumor vaccines. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and practical, Vaccine Design: Methods and Protocols, Second Edition, Volume 1: Vaccines for Human Diseases aims to be a useful practical guide to researchers to help further their study in this field.
