Tumor Micro Environment And Drug Resistance PDF Download
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Author | : Wei Zhao |
Publisher | : Frontiers Media SA |
Total Pages | : 487 |
Release | : 2022-02-16 |
Genre | : Science |
ISBN | : 2889741842 |
Download Tumor Micro-environment and Drug Resistance Book in PDF, ePub and Kindle
Author | : Shaoquan Zheng |
Publisher | : Frontiers Media SA |
Total Pages | : 156 |
Release | : 2023-09-29 |
Genre | : Medical |
ISBN | : 2832534694 |
Download Tumor microenvironment, immunotherapy, and drug resistance in breast and gastrointestinal cancer Book in PDF, ePub and Kindle
Author | : Ji-Young Kim |
Publisher | : |
Total Pages | : 0 |
Release | : 2021 |
Genre | : |
ISBN | : |
Download Mechanisms of Drug Resistance and Metastasis in the Tumor Microenvironment Book in PDF, ePub and Kindle
Author | : Giulia Adriani |
Publisher | : Frontiers Media SA |
Total Pages | : 171 |
Release | : 2023-10-26 |
Genre | : Medical |
ISBN | : 2832537030 |
Download Preclinical Models and Emerging Technologies to Study the Effects of the Tumor Microenvironment on Cancer Heterogeneity and Drug Resistance Book in PDF, ePub and Kindle
Author | : Ahmed Lasfar |
Publisher | : Frontiers Media SA |
Total Pages | : 148 |
Release | : 2020-01-27 |
Genre | : |
ISBN | : 2889632830 |
Download Tumor Microenvironment and Resistance to Current Therapies Book in PDF, ePub and Kindle
Author | : Sujit Kumar Bhutia |
Publisher | : Springer Nature |
Total Pages | : 284 |
Release | : 2020-10-24 |
Genre | : Medical |
ISBN | : 9811569304 |
Download Autophagy in tumor and tumor microenvironment Book in PDF, ePub and Kindle
This book deals with the paradoxical role of autophagy in tumor suppression and tumor promotion in cancer cells. Autophagy plays opposing, context-dependent roles in tumors; accordingly, strategies based on inhibiting or stimulating autophagy could offer as potential cancer therapies. The book elucidates the physiological role of autophagy in modulating cancer metastasis, which is the primary cause of cancer-associated mortality. Further, it reviews its role in the differentiation, development, and activation of multiple immune cells, and its potential applications in tumor immunotherapy. In addition, it examines the effect of epigenetic modifications of autophagy-associated genes in regulating tumor growth and therapeutic response and summarizes autophagy’s role in the development of resistance to a variety of anti-cancer drugs in cancer cells. In closing, it assesses autophagy as a potential therapeutic target for cancer treatment. Given its scope, the book offers a valuable asset for all oncologists and researchers who wish to understand the potential role of autophagy in tumor biology.
Author | : Marta Baiocchi |
Publisher | : Springer Nature |
Total Pages | : 247 |
Release | : 2022-07-22 |
Genre | : Medical |
ISBN | : 1071625136 |
Download Cancer Drug Resistance Book in PDF, ePub and Kindle
This volume discusses the latest techniques used to identify cancer drug resistance determinants at the molecular, cellular, and functional levels. Chapters in this book cover up-to-date topics including tumor-microenvironment cell co-culture methods and microfluidics systems; workflows for functional assessment of drug resistance in vitro and in vivo; quantitative techniques for identifying quiescent blood-flow circulating cells; and single-cell characterization methods, such as mass cytometry. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Cancer Drug Resistance: Methods and Protocols is a valuable resource for all scientists and researchers who are looking to learn more about the latest developments in understanding and overcoming anticancer drug resistance.
Author | : Anne Le |
Publisher | : Springer |
Total Pages | : 186 |
Release | : 2018-06-26 |
Genre | : Medical |
ISBN | : 331977736X |
Download The Heterogeneity of Cancer Metabolism Book in PDF, ePub and Kindle
Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.
Author | : Sameer Ullah Khan |
Publisher | : Springer Nature |
Total Pages | : 392 |
Release | : |
Genre | : |
ISBN | : 9819716667 |
Download Drug Resistance in Cancer: Mechanisms and Strategies Book in PDF, ePub and Kindle
Author | : Yasuhiro Matsumura |
Publisher | : Springer Nature |
Total Pages | : 325 |
Release | : 2020-01-07 |
Genre | : Medical |
ISBN | : 4431568808 |
Download Cancer Drug Delivery Systems Based on the Tumor Microenvironment Book in PDF, ePub and Kindle
This book proposes the importance of new systems of drug design and delivery based on cancer pathophysiology in addition to cancer molecular and cellular biology. The current studies based on molecular and cellular biology while ignoring pathophysiology and pharmacology may be leading the development of antitumor drugs in the wrong direction and wasting a lot of money. Although there have been numerous reports of genetic and phenotypic changes in tumors, a large body of pathological and clinical evidence supports the conclusion that there are no pivotal changes in tumor cells that distinguish them consistently and reliably from normal dividing cells. Unlike using antibiotics against bacterial infection, therefore, anticancer agents (ACAs) need to be delivered selectively to tumor tissues and should be kept there long enough to reproduce the concentrations they reach in the Petri dish, which is a closed space where the cytocidal effects of any anticancer agents (ACAs) including molecular targeting agents are very strong. In the body, however, administered ACAs are cleared with the passage of time. Furthermore, most human cancers possess abundant stroma that hinders the penetration of drugs into the tumor microenvironment. Therefore, to overcome these difficulties, novel drug delivery systems have been designed, such as nanoparticles and ACA conjugated antibodies to stromal components and to cancer cell surface antigens. These advances are described in this book after the first section, which describes core features of the pathophysiology of the cancer microenvironment, on which these new developments are based.