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Treatment Response and Resistance in Schizophrenia

Treatment Response and Resistance in Schizophrenia
Author: Oliver Howes
Publisher: Oxford University Press
Total Pages: 240
Release: 2018-09-13
Genre: Medical
ISBN: 0192563912

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Treatment resistant schizophrenia (TRS) is common, affecting approximately a third of patients diagnosed. Despite the prevalence of TRS, the best approach to practical management is often unclear to clinicians and patients. Treatment Response and Resistance in Schizophrenia offers a practical, clinically focused guide to TRS and the real-world challenges faced by those impacted. Over 14 chapters this resource covers the principles and practice of TRS, from the definition, epidemiology, and clinical assessment, to the pharmacological, physical, and psychological management of treatment resistance. All chapters have been written by internationally leading experts in the field to ensure busy clinicians have high-quality, applicable content that is rooted in real clinical experiences. A chapter of case studies is included to link real-life scenarios to each of the instructive chapters, illustrating approaches to practical management and application. Part of the Oxford Psychiatry Library, this useful pocket book is an invaluable resource and quick reference for psychiatrists, psychiatry trainees, and other mental health practitioners, as well as clinical psychologists, primary care physicians, and specialist nurses.


Management of Complex Treatment-resistant Psychotic Disorders

Management of Complex Treatment-resistant Psychotic Disorders
Author: Michael Cummings
Publisher: Cambridge University Press
Total Pages: 545
Release: 2021-07-22
Genre: Medical
ISBN: 1108965687

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An essential handbook providing practical guidance and medication advice on the effective management and treatment of psychotic disorders.


Treatment–Refractory Schizophrenia

Treatment–Refractory Schizophrenia
Author: Peter F. Buckley
Publisher: Springer Science & Business Media
Total Pages: 231
Release: 2014-03-18
Genre: Medical
ISBN: 3642452574

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Schizophrenia is often associated with an inadequate response to pharmacological and non-pharmacological treatments. How to treat patients who have an unsatisfactory response to anti-psychotics, including clozapine - which is unequivocally the most powerful antipsychotic medication for this recalcitrant population - remains a clinical conundrum. A range of adjunctive medications have been tried with mixed results; there has also been renewed interest in the role of neuromodulatory strategies, electroconvulsive therapy, and cognitive and vocational approaches. Perhaps a bright spot for the future lies in the evolution of pharmacogenetic approaches for individualized care. In this book, leading experts from Europe, Australia and the Americas provide a timely appraisal of treatments for the most severely ill schizophrenia patients. This clinically focused book is informed by the latest research on the neurobiology and treatment of schizophrenia. It is comprehensive in scope, covering current treatment options, various add-on approaches, and a range of psychosocial treatments. The contributors are respected experts who have combined their clinical experience with cutting-edge research to provide readers with authoritative information on fundamental aspects of clinical care for schizophrenia.


Neurobiology, Clinical Course, and Therapeutic Approaches of Treatment Resistant Schizophrenia: Toward an Integrated View

Neurobiology, Clinical Course, and Therapeutic Approaches of Treatment Resistant Schizophrenia: Toward an Integrated View
Author: Felice Iasevoli
Publisher:
Total Pages: 0
Release: 2020
Genre:
ISBN:

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.


The Recognition and Management of Early Psychosis

The Recognition and Management of Early Psychosis
Author: Patrick D. McGorry
Publisher: Cambridge University Press
Total Pages: 527
Release: 1999-07-28
Genre: Psychology
ISBN: 1139429140

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The treatment of early psychosis has been bedevilled by an entrenched pessimism, stemming from the asylum era and the Kraepelinian model of schizophrenia. More recently, however, there has been a surge of interest in preventively oriented treatment of patients showing the first signs of psychotic illness, with the realization that these illnesses are frequently highly responsive to early treatment. This is the first text to focus on the potential of early detection of psychosis, and the practicalities of treatment. Based on the pioneering experience and research of a now well-established prevention and intervention centre, and with contributions from international authorities, the book outlines a framework for intervention, reviews the evidence available to guide clinical practice, and describes models of treatment. Incorporating many personal narratives and case histories, it is strong on theory, sensitive on practical issues, and will challenge, inform and guide clinicians.


Therapy-Resistant Schizophrenia

Therapy-Resistant Schizophrenia
Author: H. Elkis
Publisher: Karger Medical and Scientific Publishers
Total Pages: 210
Release: 2010-07-29
Genre: Medical
ISBN: 3805595123

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The psychotic symptoms of up to 30% of schizophrenic patients do not respond adequately to treatment with antipsychotic drugs, other than clozapine. These refractory patients are generally among the most disabled of all people with schizophrenia and require special assessment and treatment. This volume presents the latest research and recommendations on the definition, causes and therapy of treatment-resistant schizophrenia (TRS). Methods for identification and optimal management of TRS are reviewed. Clozapine and other atypical antipsychotic drugs which are the primary treatment for TRS, as well as non-pharmacologic treatments such as transcranial magnetic stimulation, cognitive behavior therapy and ECT are discussed in depth. Potential causative factors and identifying features such as genetic factors, poor premorbid functioning, longer duration of untreated psychosis, and biological measures such as structural and functional brain abnormalities are also reviewed in depth in the present volume.


Treatment Resistance in Psychiatry

Treatment Resistance in Psychiatry
Author: Yong-Ku Kim
Publisher: Springer
Total Pages: 416
Release: 2018-10-29
Genre: Medical
ISBN: 9811043582

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This book reviews all the important aspects of treatment-resistant psychiatric disorders, covering issues such as definitions, clinical aspects, neurobiological correlates, treatment options, and predictors of treatment response. The book is divided into three sections, the first of which examines the most recent thinking on treatment resistance in psychiatry, including definition and epidemiology, paradigm shift in the study of the subjects, individual susceptibility and resilience, abnormal structural or functional connectivity, and insights from animal models. The second section then discusses treatment resistance in each of the major psychiatric disorders, with particular focus on the responsible clinical and biological factors and the available management strategies. Finally, more detailed information is presented on diverse pharmacological and non-pharmacological therapeutic interventions. The book, written by leading experts from across the world, will be of value to all who seek a better understanding of the clinical-neurobiological underpinnings and the development of management for treatment resistance in psychiatric disorders.


Psychotic Disorders

Psychotic Disorders
Author: Oliver Freudenreich
Publisher: Springer Nature
Total Pages: 479
Release: 2019-12-04
Genre: Medical
ISBN: 3030294501

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This book provides clear and concise guidance for clinicians when they encounter a patient with psychosis, starting with the medical work-up to arrive at a diagnosis and ending with the comprehensive care for patients with established schizophrenia. It covers the optimal use of medications (emphasizing safe use) but also addresses other treatment approaches (psychological treatments, rehabilitation) and the larger societal context of care, including how to work effectively in complex systems. It uniquely condenses the literature into teaching points without simplifying too much, effectively serving as a learning tool for trainees and professionals. For this second edition, the book was extensively updated and its content expanded, with new figures as well. Each chapter begins with an initial summary and includes Tips and Key Points in text boxes. Each chapter also includes links to external websites and additional readings. The book contains clinical and practical wisdom for clinicians who are treating real patients at the front lines, setting it apart from all other texts. Psychotic Disorders is an excellent resource for medical students, early career professionals such as trainees and fellows, and related clinicians seeking additional training and resources, including those in psychiatry, psychology, neurology, and all others.


Practice Guideline for the Treatment of Patients with Schizophrenia

Practice Guideline for the Treatment of Patients with Schizophrenia
Author: American Psychiatric Association
Publisher: American Psychiatric Publishing
Total Pages: 164
Release: 1997
Genre: Schizophrenia
ISBN: 9780890423097

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The American Psychiatric Association (APA) is accredited by the Accreditation Council for Continuing Medical Education to sponsor continuing medical education for physicians.