Translational Radiation Oncology PDF Download
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| Author | : Adam Eltorai |
| Publisher | : Elsevier |
| Total Pages | : 736 |
| Release | : 2023-08-01 |
| Genre | : Science |
| ISBN | : 0323884245 |
Download Translational Radiation Oncology Book in PDF, ePub and Kindle
Translational Radiation Oncology covers the principles of evidence-based medicine and applies them to the design of translational research. The book provides valuable discussions on the critical appraisal of published studies and recent developments in radiation oncology, allowing readers to learn how to evaluate the quality of such studies with respect to measuring outcomes and make effective use of all types of evidence. By reading this book, researchers have access to a practical approach to help them navigate challenging considerations in study design and implementation. It is a valuable resource for researchers, oncologists and members of biomedical field who want to understand more about translational research applied to the field of radiation oncology. Translational medicine serves as an indispensable tool in grant writing and funding efforts, so understanding how to apply its principles to research is necessary to guarantee that results will be impactful to patients. Provides a clear process for understanding, designing, executing and analyzing clinical and translational research Presents practical, step-by-step guidance to help readers take ideas from the lab to the bedside Written by a team of oncologists, radiologists and clinical research experts that fully cover translational research in radiation oncology
| Author | : Juliana Denekamp |
| Publisher | : |
| Total Pages | : |
| Release | : 2001 |
| Genre | : |
| ISBN | : |
Download Translational Research in Radiation Oncology Book in PDF, ePub and Kindle
| Author | : Sivapatham Sundaresan |
| Publisher | : |
| Total Pages | : |
| Release | : 2021 |
| Genre | : Cancer |
| ISBN | : 9781838805357 |
Download Translational Research in Cancer Book in PDF, ePub and Kindle
| Author | : Simon S. Lo |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 433 |
| Release | : 2012-08-28 |
| Genre | : Medical |
| ISBN | : 364225604X |
Download Stereotactic Body Radiation Therapy Book in PDF, ePub and Kindle
Stereotactic body radiation therapy (SBRT) has emerged as an important innovative treatment for various primary and metastatic cancers. This book provides a comprehensive and up-to-date account of the physical/technological, biological, and clinical aspects of SBRT. It will serve as a detailed resource for this rapidly developing treatment modality. The organ sites covered include lung, liver, spine, pancreas, prostate, adrenal, head and neck, and female reproductive tract. Retrospective studies and prospective clinical trials on SBRT for various organ sites from around the world are examined, and toxicities and normal tissue constraints are discussed. This book features unique insights from world-renowned experts in SBRT from North America, Asia, and Europe. It will be necessary reading for radiation oncologists, radiation oncology residents and fellows, medical physicists, medical physics residents, medical oncologists, surgical oncologists, and cancer scientists.
| Author | : Eleanor E.R. Harris |
| Publisher | : |
| Total Pages | : 30 |
| Release | : 2006 |
| Genre | : Breast |
| ISBN | : |
Download Investigating the Role of Radiation Therapy Breast Cancer Clinical and Translational Research Book in PDF, ePub and Kindle
| Author | : Sivapatham Sundaresan |
| Publisher | : BoD – Books on Demand |
| Total Pages | : 212 |
| Release | : 2021-02-03 |
| Genre | : Medical |
| ISBN | : 1838805346 |
Download Translational Research in Cancer Book in PDF, ePub and Kindle
Translational research in oncology benefits from an abundance of knowledge resulting from genome-scale studies concerning the molecular pathways involved in tumorigenesis. Translational oncology represents a bridge between basic research and clinical practice in cancer medicine. The vast majority of cancer cases are due to environmental risk factors. Many of these environmental factors are controllable lifestyle choices. Experimental cancer treatments are studied in clinical trials to compare the proposed treatment to the best existing treatment through translational research. The key features of the book include: 1) New screening for the development of radioprotectors: radioprotection and anti-cancer effect of β-Glucan (Enterococcus faecalis) 2) Translational perspective on hepatocellular carcinoma 3) Brachytherapy for endometrial cancer 4) Discovery of small molecule inhibitors for histone methyltransferases in cancer
| Author | : Philip J. Tofilon |
| Publisher | : Springer |
| Total Pages | : 280 |
| Release | : 2016-11-21 |
| Genre | : Medical |
| ISBN | : 3319408542 |
Download Increasing the Therapeutic Ratio of Radiotherapy Book in PDF, ePub and Kindle
Current cancer therapies are focused on three general strategies: modifying intrinsic radiosensitivity via molecular targeting, manipulating microenvironmental factors to enhance tumor susceptibility to radiation, and improving delivery of radiation to critical tumor locations while sparing normal tissues. The goal of this volume is to describe a number of promising approaches corresponding to each strategy. In general, research in radiation oncology tends to be siloed into fundamental biology, physics or treatment delivery. The strategies for improving therapeutic ratio encompassed in this book will involve each of these components of radiation oncology. Thus, they will illustrate the variety of disparate approaches available for potentially improving the efficacy of radiotherapy, which may then stimulate discussion across disciplines and foster further translational investigations. Although a goal of each chapter will be to highlight advances within an approach, of equal importance will be the delineation of barriers to successful clinical application and how to overcome or minimize such impediments. Along these lines, because therapeutic ratio incorporates both tumor and normal tissue radio response, a point of emphasis will be the mechanistic rationale for selectively modifying tumor (sensitization) or normal cells (protection). Finally, whereas the literature is replete with studies describing potential targets/strategies for increasing the therapeutic ratio for radiotherapy, this book will focus on those supported by in vivo data consistent with impending translational application along with those that are already being evaluated in the clinic.
| Author | : Tejinder Kataria |
| Publisher | : BoD – Books on Demand |
| Total Pages | : 230 |
| Release | : 2013-07-03 |
| Genre | : Science |
| ISBN | : 9535111639 |
Download Frontiers in Radiation Oncology Book in PDF, ePub and Kindle
The mode of action by radiation is postulated to be the production of double strand breaks of DNA. The repair of double strand breaks occurs through non homologous end joining through acetylation of histone proteins by histone acetyltransferases (HATs). The fixation of double strand breaks through HAT inhibitors is a promising application for radiation sensitization in the clinic. P53 is a tumour suppressor gene and its mutation has been implicated in 60% of human cancers. As one of the pivotal anticancer genes, P53 controls the transcription and translation of a series of genes. The kinetics of DNA double strand break generation and their co relation to P53 status, ATM and ARF activation are computed and modelled for understanding the potential of such research.
| Author | : Laurence J. N. Cooper |
| Publisher | : John Wiley & Sons |
| Total Pages | : 306 |
| Release | : 2018-05-01 |
| Genre | : Medical |
| ISBN | : 1118123220 |
Download Immunotherapy in Translational Cancer Research Book in PDF, ePub and Kindle
A guide to state-of-the-art cancer immunotherapy in translational cancer research A volume in the Translational Oncology series, Immunotherapy in Translational Cancer Research explores the recent developments in the role that immunotherapy plays in the treatment of a wide range of cancers. The editors present key concepts, illustrative examples, and suggest alternative strategies in order to achieve individualized targeted therapy. Comprehensive in scope, Immunotherapy in Translational Cancer Research reviews the relevant history, current state, and the future of burgeoning cancer-fighting therapies. The book also includes critical information on drug development, clinical trials, and governmental resources and regulatory issues. Each chapter is created to feature: development of the immunotherapy; challenges that have been overcome in order to scale up and undertake clinical trials; and clinical experience and application of research. This authoritative volume is edited by a team of noted experts from MD Anderson Cancer Center, the world’s foremost cancer research and care center and: Offers a comprehensive presentation of state-of-the-art cancer immunotherapy research that accelerates the pace of clinical cancer care Filled with the concepts, examples, and approaches for developing individualized therapy Explores the breath of treatments that reflect the complexity of the immune system itself Includes contributions from a panel international experts in the field of immunotherapy Designed for physicians, medical students, scientists, pharmaceutical executives, public health and public policy government leaders and community oncologists, this essential resource offers a guide to the bidirectional interaction between laboratory and clinic immunotherapy cancer research.
| Author | : Kishan J. Pandya |
| Publisher | : CRC Press |
| Total Pages | : 280 |
| Release | : 2016-04-19 |
| Genre | : Health & Fitness |
| ISBN | : 1420020358 |
Download Lung Cancer Book in PDF, ePub and Kindle
Lung cancer is the leading cause of cancer-related deaths in the United States. Filling a gap in the literature, this resource translates recent laboratory findings into practical applications for the prevention and control of lung cancer. Featuring chapters by seasoned researchers in the field, this reference reviews current advances in imaging, d
